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Advances in co-opting anti-depressant drugs in glioma therapy. Cell reports. Medicine Pant, A., Lim, M. 2022; 3 (12): 100837
Abstract
A study by Chryplewicz etal. demonstrated the efficacy of combining tricyclic antidepressant imipramine and anti-VEGF therapy in treating genetically engineered glioma models. Dual therapy synergistically improved vascular integrity, increased autophagy, and modulated the myeloid and lymphoid compartments in glioma.
View details for DOI 10.1016/j.xcrm.2022.100837
View details for PubMedID 36543105