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Reverse Transcribing the Code for Chromosome Stability MOLECULAR CELL Artandi, S. E., Cooper, J. P. 2009; 36 (5): 715-719

Abstract

The linearity of eukaryotic chromosomes presents challenges to cells, as the presence of DNA "ends" poses problems for the DNA replication machinery and the cell's damage response systems. This year's Nobel Prize in Physiology or Medicine recognized groundbreaking studies establishing the telomere field as a crucial area of biomedical research.

View details for DOI 10.1016/j.molcel.2009.11.030

View details for Web of Science ID 000272965400001

View details for PubMedID 20005831