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Light microscopy mapping of connections in the intact brain TRENDS IN COGNITIVE SCIENCES Kim, S., Chung, K., Deisseroth, K. 2013; 17 (12): 596-599

Abstract

Mapping of neural connectivity across the mammalian brain is a daunting and exciting prospect. Current approaches can be divided into three classes: macroscale, focusing on coarse inter-regional connectivity; mesoscale, involving a finer focus on neurons and projections; and microscale, reconstructing full details of all synaptic contacts. It remains to be determined how to bridge the datasets or insights from the different levels of study. Here we review recent light-microscopy-based approaches that may help in integration across scales.

View details for DOI 10.1016/j.tics.2013.10.005

View details for Web of Science ID 000328719600002

View details for PubMedID 24210964