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A personalized approach to lymphoproliferations in patients with inborn errors of immunity. Seminars in diagnostic pathology Naor, S., Adam, E., Schiby, G., Gratzinger, D. 2023

Abstract

Biopsies from patients with inborn error of immunity (IEI) may pose a diagnostic challenge due to the abnormal anatomy of their lymphoid organs and the tendency for the development of lymphoproliferations in various organs, some of which may lead to the wrong impression of malignant lymphoma which may prompt aggressive unnecessary treatment. In this article we will review typical histologic findings in various IEI's described in the literature and discuss the appropriate approach to the diagnosis of lymphoproliferations in these patients by presenting illustrative cases.

View details for DOI 10.1053/j.semdp.2023.07.001

View details for PubMedID 37479638