The Serpentine Sign: A Reliable Endoscopic and Radiographic Finding in Empty Nose Syndrome. The Laryngoscope Dholakia, S. S., Grimm, D., Daum, R., Bravo, D. T., Salvi, N., Zarabanda, D., Overdevest, J. B., Thamboo, A., Nakayama, T., Nayak, J. V. 2023


Empty nose syndrome (ENS) is a relatively uncommon disease that greatly impacts the quality of life and presents diagnostic challenges. We sought to identify objective clinical findings unique to patients with ENS, and in doing so identified compensatory mucosal hypertrophy in an alternating, undulating swelling on endoscopy and coronal computerized tomography (CT) that we have termed the "Serpentine Sign." Here, we investigated whether this radiographic finding is a reliable manifestation in ENS patients.Retrospective review was undertaken to identify ENS patients with past turbinoplasty, an ENS6Q score of at least 11/30, and symptomatic improvement with the cotton placement test. Control patients without complaints of ENS symptoms (ENS6Q?

View details for DOI 10.1002/lary.30938

View details for PubMedID 37702458