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Performance of RAPID noncontrast CT stroke platform in large vessel occlusion and intracranial hemorrhage detection. Frontiers in neurology Yedavalli, V., Heit, J. J., Dehkharghani, S., Haerian, H., Mcmenamy, J., Honce, J., Timpone, V. M., Harnain, C., Kesselman, A., Filly, A., Beardsley, A., Sakamoto, B., Song, C., Montuori, J., Navot, B., Mena, F. V., Giurgiutiu, D. V., Kitamura, F., Lima, F. O., Silva, H., Mont'Alverne, F. J., Albers, G. 2023; 14: 1324088

Abstract

Noncontrast CT (NCCT) is used to evaluate for intracerebral hemorrhage (ICH) and ischemia in acute ischemic stroke (AIS). Large vessel occlusions (LVOs) are a major cause of AIS, but challenging to detect on NCCT.The purpose of this study is to evaluate an AI software called RAPID NCCT Stroke (RAPID, iSchemaView, Menlo Park, CA) for ICH and LVO detection compared to expert readers.In this IRB approved retrospective, multicenter study, stand-alone performance of the software was assessed based on the consensus of 3 neuroradiologists and sensitivity and specificity were determined. The platform's performance was then compared to interpretation by readers comprised of eight general radiologists (GR) and three neuroradiologists (NR) in detecting ICH and hyperdense vessel sign (HVS) indicating LVO.A total of 244 cases were included. Of the 244, 115 were LVOs and 26 were ICHs. One hundred three cases did not have LVO nor ICH. Stand-alone performance of the software demonstrated sensitivities and specificities of 96.2 and 99.5% for ICH and 63.5 and 95.1% for LVO detection. Compared to all 11 readers and eight GR readers only respectively, the software demonstrated superiority, achieving significantly higher sensitivities (63.5% versus 43.6%, p?

View details for DOI 10.3389/fneur.2023.1324088

View details for PubMedID 38156093

View details for PubMedCentralID PMC10753184