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Pretreatment CTP Collateral Parameters Predict Good Outcomes in Successfully Recanalized Middle Cerebral Artery Distal Medium Vessel Occlusions. Clinical neuroradiology Yedavalli, V., Koneru, M., Hamam, O., Hoseinyazdi, M., Marsh, E. B., Llinas, R., Urrutia, V., Leigh, R., Gonzalez, F., Xu, R., Caplan, J., Huang, J., Lu, H., Wintermark, M., Heit, J., Guenego, A., Albers, G., Nael, K., Hillis, A. 2023

Abstract

Distal medium vessel occlusions (DMVOs) account for a large percentage of vessel occlusions resulting in acute ischemic stroke (AIS) with disabling symptoms. We aim to assess whether pretreatment quantitative CTP collateral status (CS) parameters can serve as imaging biomarkers for good clinical outcomes prediction in successfully recanalized middle cerebral artery (MCA) DMVOs.We performed a retrospective analysis of consecutive patients with AIS secondary to primary MCA-DMVOs who were successfully recanalized by mechanical thrombectomy (MT) defined as modified thrombolysis in cerebral infarction (mTICI) 2b, 2c, or 3. We evaluated the association between the CBV index and HIR independently with good clinical outcomes (modified Rankin score 0-2) using Spearman rank correlation, logistic regression, and ROC analyses.From 22 August 2018 to 18 October 2022 8/22/2018 to 10/18/2022, 60 consecutive patients met our inclusion criteria (mean age 71.2?±?13.9 years old [mean?±?SD], 35 female). The CBV index (r?=?-0.693, p?

View details for DOI 10.1007/s00062-023-01371-2

View details for PubMedID 38155255

View details for PubMedCentralID 7668337