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EVALUATION OF ACUTE-RENAL-FAILURE WITH MAGNETIC-RESONANCE-IMAGING USING GRADIENT-ECHO AND GD-DTPA

EVALUATION OF ACUTE-RENAL-FAILURE WITH MAGNETIC-RESONANCE-IMAGING USING GRADIENT-ECHO AND GD-DTPA INVESTIGATIVE RADIOLOGY Munechika, H., SULLIVAN, D. C., Hedlund, L. W., Beam, C. A., Sostman, H. D., Herfkens, R. J., Pelc, N. J. 1991; 26 (1): 22-27

Abstract

Detection of acute renal failure (ARF) using fast-scan magnetic resonance imaging (MRI) with Gd-DTPA was studied in a dog model. ARF was produced in five dogs by infusion of norepinephrine (0.75 micrograms/kg/min) into the renal arteries for 40 minutes. MRI was performed 1 hour later and compared with baseline (pre-ARF) MRI. There was no significant difference in the ratios of signal intensity-vs.-time curves from 0 to 35 seconds after injection of Gd-DTPA. However, a difference between the outer and inner medulla was significant in the time period of 5 to 20 minutes after Gd-DTPA injection. These later signal intensity differences by fast-scan (gradient-echo) technique may be useful in the evaluation of ARF.

View details for Web of Science ID A1991ER52500005

View details for PubMedID 2022449