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Neuromodulatory Focused Ultrasound for Epilepsy: Are Animal Models Useful? ACS chemical neuroscience Chu, P., Yu, H., Fisher, R. S., Liu, H. 2024

Abstract

Ultrasound neuromodulation is a potential alternative therapy for suppressing epileptic discharges. Recently, several human clinical trials have reported promising results from repeated focused ultrasound (FUS) treatments for temporal lobe epilepsy. In this Viewpoint, we highlight the valuable guidance of preclinical validation methods for choosing the optimal FUS parameters, thus ensuring consistency with the outcomes of clinical trials and leading human trials to the safest and most effective approaches.

View details for DOI 10.1021/acschemneuro.4c00198

View details for PubMedID 38634833