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The Myc Connection: ES Cells and Cancer
The Myc Connection: ES Cells and Cancer CELL Rothenberg, M. E., Clarke, M. F., Diehn, M. 2010; 143 (2): 184-186Abstract
Gene profiling experiments have revealed similarities between cancer and embryonic stem (ES) cells. Kim et al. (2010) dissect the gene expression signature of ES cells into three functional modules and find that the Myc module, including genes targeted by Myc-interacting proteins, accounts for most of the similarity between ES and cancer cells.
View details for DOI 10.1016/j.cell.2010.09.046
View details for Web of Science ID 000283052200007
View details for PubMedID 20946977