Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing

Trial ID or NCT#

NCT01556828

Status

not recruiting iconNOT RECRUITING

Purpose

The goal of this study is to identify genetic changes associated with the initiation, progression, and treatment response of response of cutaneous and hematologic disorders using recently developed high-throughput sequencing technologies. The improved understanding of the genetic changes associated with cutaneous and hematologic disorders may lead to improved diagnostic, prognostic and therapeutic options for these disorders.

Official Title

Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - 18 years of age or older - Patient meets the clinical and/or pathologic criteria for the cutaneous or hematologic disorder being examined. - Patient is willing to provide skin biopsies and five 10 mL tubes of peripheral blood.
Exclusion Criteria:
  1. - Less than 18 years of age

Investigator(s)

Paul A. Khavari, MD, PhD
Paul A. Khavari, MD, PhD
Dermatologist, Cutaneous oncology specialist, Medical oncologist
Carl J. Herzog Professor of Dermatology in the School of Medicine
Carolyn Lee MD PhD
Carolyn Lee MD PhD
Dermatologist, General dermatologist, Dermatologic oncologist, Cutaneous oncology specialist
Assistant Professor of Dermatology
Sumaira Z. Aasi, MD
Sumaira Z. Aasi, MD
Dermatologist, Mohs surgeon, Cutaneous oncology specialist, Dermatologic surgeon
Clinical Professor, Dermatology
Susan M. Swetter, MD
Susan M. Swetter, MD
Dermatologist, Dermatologic oncologist, Cutaneous oncology specialist, Melanoma specialist
Professor of Dermatology
Youn H Kim, MD
Youn H Kim, MD
Dermatologic oncologist, Cutaneous oncology specialist, Dermatologist
The Joanne and Peter Haas, Jr., Professor for Cutaneous Lymphoma Research and Professor, by courtesy, of Medicine (Oncology)