Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

Trial ID or NCT#



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The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hours total treatment time).

Official Title

Comparative Effectiveness of Online Cognitive Behavioral Therapy vs. An Online Single-Session Pain Relief Skills Class for Chronic Pain - The PROGRESS Study

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. 1. At least 18 years of age or older of either sex (and all genders). 2. Chronic pain (pain that occurs on at least half of the days of 3 months or more). 3. Past-month average pain intensity score of at least 3/10. 4. Ability to adhere to and complete study protocols.
Exclusion Criteria:
  1. 1. Inability to provide informed consent. 2. Cognitive impairment, non-English speaking, or psychological factors that would preclude comprehension of material and/or full participation in the study including group treatment. 3. Active suicidality at screening. 4. Study staff may exclude individuals with a known history of disruptive behavior to minimize contamination of the learning environment for an entire treatment cohort. 5. Receipt of either study treatment in the past 3 months.


Beth Darnall
Beth Darnall
Pain management specialist, Pain psychologist
Professor of Anesthesiology, Perioperative and Pain Medicine (Adult Pain) and, by courtesy, of Psychiatry and Behavioral Sciences (General Psychiatry & Psychology (Adult))

Contact us to find out if this trial is right for you.


Emma A Adair, BS