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Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Trial ID or NCT#

NCT00946673

Status

NOT RECRUITING

Purpose

The purpose of this study is to determine the maximum tolerated dose (MTD) of vorinostat given concurrently with stereotactic radiosurgery (SRS) to treat non-small cell lung cancer (NSCLCA) brain metastases in patient with 1-4 lesions.

Official Title

A Phase I Trial of Vorinostat Concurrent With Stereotactic Radiotherapy in Treatment of Brain Metastases From Non-Small Cell Lung Cancer

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years

Sexes Eligible for Study: All

Accepts Healthy Volunteers: No

View All Criteria

Investigator(s)

Griffith Harsh, MD

Neurosurgeon

Professor of Neurosurgery and, by courtesy, of Otolaryngology-Head and Neck Surgery at the Stanford University Medical Center

Iris C. Gibbs, MD, FACR

Radiation oncologist, Neuro-oncologist

Professor of Radiation Oncology (Radiation Therapy) at the Stanford University Medical Center

Steven D. Chang, MD

Neurosurgeon, Aneurysm neurosurgeon, Cerebrovascular neurosurgeon, Pituitary tumors neurosurgeon, Stereotactic neurosurgeon, Neuro-oncologist

Robert C. and Jeannette Powell Neurosciences Professor and, by courtesy, of Otolaryngology-Head and Neck Surgery

Scott G. Soltys, MD

Radiation oncologist

Associate Professor of Radiation Oncology (Radiation Therapy) at the Stanford University Medical Center

Heather Wakelee, MD

Medical oncologist, Thoracic specialist

Professor of Medicine (Oncology) at the Stanford University Medical Center

Joel Neal, MD, PhD

Medical oncologist, Thoracic specialist

Assistant Professor of Medicine (Oncology) at the Stanford University Medical Center

CONTACT

Ccto-office@stanford.edu
(650) 498-7061

SEND MESSAGE

View on ClinicalTrials.gov

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