Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Trial ID or NCT#

NCT03430206

Status

not recruiting iconNOT RECRUITING

Purpose

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can safely prevent desaturation events in children under anesthesia.

Official Title

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Eligibility Criteria

Ages Eligible for Study: Younger than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - Pediatric patients less than or equal to 18 years old undergoing general anesthesia for procedures or surgeries at Lucile Packard Children's Hospital.
Exclusion Criteria:
  1. - Pregnancy, absence of parent or legal guardian able to provide written consent for study participation, anatomical or surgical contraindications (epistaxis, basilar skull fractures or abnormalities, nasal surgery or obstruction, nasal fractures, nasal vascular abnormalities), papillomatosis, tracheostomy, emergent surgery for which application of HFNC might delay surgery or might result in increased aspiration risk.

Investigator(s)

Thomas Caruso
Anesthesiologist
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Chi-Ho Ban Tsui
Samuel Rodriguez, MD
Anesthesiologist
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Douglas Sidell, MD
Douglas Sidell, MD
Pediatric otolaryngologist, Surgeon
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
Romy Yun
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
Anna H. Messner, MD
Ellen Wang
Ellen Wang
Anesthesiologist
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine

Contact us to find out if this trial is right for you.

Contact

Thomas J Caruso, M.D., M.Ed.
650-723-5728