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One-year objective and functional outcomes of a randomized clinical trial of vaginal mesh for prolapse 31st Annual Scientific Meeting of the American-Urogynecologic-Society Sokol, A. I., Iglesia, C. B., Kudish, B. I., Gutman, R. E., Shveiky, D., Bercik, R., Sokol, E. R. MOSBY-ELSEVIER. 2012

Abstract

The purpose of this study was to show 12-month outcomes of a randomized trial that compared vaginal prolapse repair with and without mesh.Women with stage =2 prolapse were assigned randomly to vaginal repair with or without mesh. The primary outcome was prolapse stage =1 at 12 months. Secondary outcomes included quality of life and complications.All 65 evaluable participants were followed for 12 months after trial stoppage for mesh exposures. Thirty-two women had mesh repair; 33 women had traditional repair. At 12 months, both groups had improvement of pelvic organ prolapse-quantification test points to similar recurrence rates. The quality of life improved and did not differ between groups: 96.2% mesh vs 90.9% no-mesh subjects reported a cure of bulge symptoms; 15.6% had mesh exposures, and reoperation rates were higher with mesh.Objective and subjective improvement is seen after vaginal prolapse repair with or without mesh. However, mesh resulted in a higher reoperation rate and did not improve 1-year cure.

View details for DOI 10.1016/j.ajog.2011.08.003

View details for Web of Science ID 000298369200037

View details for PubMedID 21974992