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Modulating T-cell homeostasis with IL-7: preclinical and clinical studies JOURNAL OF INTERNAL MEDICINE Capitini, C. M., CHISTI, A. A., Mackall, C. L. 2009; 266 (2): 141-153
Abstract
Interleukin-7 (IL-7) is required for the development and survival of T cells and plays a critical role in modulating T-cell homeostasis. This review will address current understanding of IL-7 biology, review recent clinical experiences and discuss potential future clinical applications of IL-7, or IL-7 blockade, in the setting of disease.
View details for DOI 10.1111/j.1365-2796.2009.02085.x
View details for Web of Science ID 000267883100001
View details for PubMedID 19623690