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Abstract
To examine the integrity of sleep-promoting neurons of the ventrolateral preoptic nucleus (VLPO) in postmortem brains of narcolepsy type 1 patients.Postmortem examination of five narcolepsy and eight control brains.VLPO galanin neuron count did not differ between narcolepsy patients (11,151 ± 3,656) and controls (13,526 ± 9,544).A normal number of galanin-immunoreactive VLPO neurons in narcolepsy type 1 brains at autopsy suggests that VLPO cell loss is an unlikely explanation for the sleep fragmentation that often accompanies the disease.
View details for DOI 10.5665/sleep.5754
View details for Web of Science ID 000375188400013
View details for PubMedID 26951397
View details for PubMedCentralID PMC4835304