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Abstract
To report the finding and management of a case of Leydig cell tumor discovered during the infertility evaluation of a patient with mosaic Klinefelter syndrome.Single case report.Academic hospital.Patient seeking assistance with fertility after a diagnosis of mosaic Klinefelter syndrome.The patient underwent microscopic testicular sperm extraction (mTESE) for sperm identification after the diagnosis of mosaic Klinefelter syndrome. Abnormal testicular tissue was identified during mTESE and histologically confirmed to be a Leydig cell tumor. The patient was informed of this incidental discovery and later underwent orchiectomy for conservative oncologic control.Histologic testicular assessment.Patient was found to have no viable sperm on mTESE, but achieved oncologic control with bilateral orchiectomy.The presented case emphasizes the importance of awareness and expedient appropriate management to achieve oncologic control of a rare tumor with low malignant potential discovered during otherwise routine mTESE. In particular, it highlights the role of the infertility specialist in aiding in diagnosis and treatment of incidental and rare findings.
View details for DOI 10.1016/j.fertnstert.2016.07.1116
View details for Web of Science ID 000386829800018
View details for PubMedID 27523297