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Abstract
PURPOSE: To evaluate outcomes of unilateral cataract surgery in children ages 7 to 24 months DESIGN: Retrospective case series at 10 Infant Aphakia Treatment Study (IATS) sites.PARTICIPANTS: The Toddler Aphakia and Pseudophakia Study (TAPS) is a registry of children treated by surgeons who participated in the Infant Aphakia Treatment Study.INTERVENTION: Children underwent unilateral cataract surgery with or without intraocular lens (IOL) placement during the IATS enrollment years of 2004 and 2010.MAIN OUTCOME MEASURES: Intraoperative complications, adverse events, visual acuity, strabismus.RESULTS: 56 children were included with a mean post-operative follow-up of 47.6 months. Median age at cataract surgery was 13.9 months (range 7.2 - 22.9). 92% received a primary IOL. Intraoperative complications occurred in 4 patients (7%). At 5 years of age, visual acuity of treated eyes was very good (>20/40) in 11% and poor (<20/200) in 44%. Adverse events were identified in 24% with a 4% incidence of glaucoma suspect. An additional unplanned intraocular surgery occurred in 14% of children. Neither adverse events (AE) or intraocular reoperations were more common for children with surgery at age 7 to 12 months than those who had surgery at 13 to 24 months (AE 21% vs. 25% (p = 0.60), reoperations 13% verses 16% (p=1.00).CONCLUSIONS: Although most children had IOL implantation concurrent with unilateral cataract removal, the incidence of complications, reoperations, and glaucoma was low when surgery is performed between 7 and 24 months of age, and compared favorably to same-site IATS data for infants operated before 7 months of age. Our study shows that IOL implantation is relatively safe in children over 6 months and less than two years of age.
View details for PubMedID 30880109