Marion S. Buckwalter, MD, PhD

Neurocritical care specialist

Stroke Center

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-6469
Learn More About the Clinic Getting Here Make An Appointment

Neurocritical Care Program

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 866-742-4811
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Internship: Univ of California San Francisco (1997) CA

Fellowship: UCSF Medical Center (2002) CA

Residency: UCSF Medical Center (2000) CA

Board Certification, United Council for Neurologic Subspecialties, Neurocritical Care (2008)

Board Certification: Neurology, American Board of Psychiatry and Neurology (2001)

Medical Education: University of Michigan School of Medicine (1996) MI

MD PhD, University of Michigan, Human Genetics (1996)

Internship, UCSF, Medicine (1997)

Residency, UCSF, Neurology (2000)

Fellowship, UCSF, Neurological Critical Care (2002)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

A mouse model of permanent focal ischemia: distal middle cerebral artery occlusion.
Doyle, K. P., & Buckwalter, M. S. (2014). A mouse model of permanent focal ischemia: distal middle cerebral artery occlusion. Methods in molecular biology (Clifton, N.J.), 1135, 103-110.

Chronic Over-Expression of TGF beta 1 Alters Hippocampal Structure and Causes Learning Deficits
Martinez-Canabal, A., Wheeler, A. L., Sarkis, D., Lerch, J. P., Lu, W.-Y., & Frankland, P. W. (2013). Chronic Over-Expression of TGF beta 1 Alters Hippocampal Structure and Causes Learning Deficits. HIPPOCAMPUS, 23(12), 1198-1211.

Suppression of Inflammation with Conditional Deletion of the Prostaglandin E-2 EP2 Receptor in Macrophages and Brain Microglia
Johansson, J. U., Pradhan, S., Lokteva, L. A., Woodling, N. S., Ko, N., & Andreasson, K. I. (2013). Suppression of Inflammation with Conditional Deletion of the Prostaglandin E-2 EP2 Receptor in Macrophages and Brain Microglia. JOURNAL OF NEUROSCIENCE, 33(40), 16016-16032.

Serum Neuron-Specific Enolase Levels from the Same Patients Differ Between Laboratories: Assessment of a Prospective Post-cardiac Arrest Cohort.
Mlynash, M., Buckwalter, M. S., Okada, A., Caulfield, A. F., Venkatasubramanian, C., & Wijman, C. Ac. (2013). Serum Neuron-Specific Enolase Levels from the Same Patients Differ Between Laboratories: Assessment of a Prospective Post-cardiac Arrest Cohort. Neurocritical care, 19(2), 161-166.

A small molecule p75(NTR) ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model.
Knowles, J. K., Simmons, D. A., Nguyen, T.-V. V., Vander Griend, L., Xie, Y., & Longo, F. M. (2013). A small molecule p75(NTR) ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiology of aging, 34(8), 2052-2063.

Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis
Kim, S. Y., Buckwalter, M., Soreq, H., Vezzani, A., & Kaufer, D. (2012). Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. EPILEPSIA, 53, 37-44.

Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model.
Pollak, J., Doyle, K. P., Mamer, L., Shamloo, M., & Buckwalter, M. S. (2012). Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model. Brain and behavior, 2(5), 698-706.

Delayed Administration of a Small Molecule Tropomyosin-Related Kinase B Ligand Promotes Recovery After Hypoxic-Ischemic Stroke
Han, J., Pollak, J., Yang, T., Siddiqui, M. R., Doyle, K. P., & Buckwalter, M. S. (2012). Delayed Administration of a Small Molecule Tropomyosin-Related Kinase B Ligand Promotes Recovery After Hypoxic-Ischemic Stroke. STROKE, 43(7), 1918-1924.

The double-edged sword of inflammation after stroke: What sharpens each edge?
Doyle, K. P., & Buckwalter, M. S. (2012). The double-edged sword of inflammation after stroke: What sharpens each edge?. ANNALS OF NEUROLOGY, 71(6), 729-731.

Distal hypoxic stroke: A new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit
Doyle, K. P., Fathali, N., Siddiqui, M. R., & Buckwalter, M. S. (2012). Distal hypoxic stroke: A new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit. JOURNAL OF NEUROSCIENCE METHODS, 207(1), 31-40.

A comparison of cooling techniques to treat cardiac arrest patients with hypothermia.
Finley Caulfield, A., Rachabattula, S., Eyngorn, I., Hamilton, S. A., Kalimuthu, R., & Wijman, C. Ac. (2011). A comparison of cooling techniques to treat cardiac arrest patients with hypothermia. Stroke research and treatment, 2011, 690506-?.

TGF beta signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke
Doyle, K. P., Cekanaviciute, E., Mamer, L. E., & Buckwalter, M. S. (2010). TGF beta signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke. JOURNAL OF NEUROINFLAMMATION, 7.

Outcome prediction in mechanically ventilated neurologic patients by junior neurointensivists
Caulfield, A. F., GABLER, L., Lansberg, M. G., Eyngorn, I., Mlynash, M., & Wijman, C. Ac. (2010). Outcome prediction in mechanically ventilated neurologic patients by junior neurointensivists. NEUROLOGY, 74(14), 1096-1101.

Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis
Luo, J., Ho, P. P., Buckwalter, M. S., Hsu, T., Lee, L. Y., & Wyss-Coray, T. (2007). Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. JOURNAL OF CLINICAL INVESTIGATION, 117(11), 3306-3315.

Increased T cell recruitment to the CNS after amyloid beta(1-42) immunization in Alzheimer's mice overproducing transforming growth factor-beta 1
Buckwalter, M. S., Coleman, B. S., Buttini, M., Barbour, R., Schenk, D., & Wyss-Coray, T. (2006). Increased T cell recruitment to the CNS after amyloid beta(1-42) immunization in Alzheimer's mice overproducing transforming growth factor-beta 1. JOURNAL OF NEUROSCIENCE, 26(44), 11437-11441.

Chronically increased transforming growth factor-beta 1 strongly inhibits hippocampal neurogenesis in aged mice
Buckwalter, M. S., Yamane, M., Coleman, B. S., Ormerod, B. K., Chin, J. T., & Wyss-Coray, T. (2006). Chronically increased transforming growth factor-beta 1 strongly inhibits hippocampal neurogenesis in aged mice. AMERICAN JOURNAL OF PATHOLOGY, 169(1), 154-164.

Modelling neuroinflammatory phenotypes in vivo
Buckwalter, M. S., & Wyss-Coray, T. (2004). Modelling neuroinflammatory phenotypes in vivo. JOURNAL OF NEUROINFLAMMATION, 1.

Modelling neuroinflammatory phenotypes in vivo.
Buckwalter, M. S., & Wyss-Coray, T. (2004). Modelling neuroinflammatory phenotypes in vivo. Journal of neuroinflammation, 1(1), 10.

Molecular and functional dissection of TGF-beta 1-induced cerebrovascular abnormalities in transgenic mice
Buckwalter, M., Pepper, J. P., Gaertner, R. F., Von Euw, D., Lacombe, P., & Wyss-Coray, T. (2002). Molecular and functional dissection of TGF-beta 1-induced cerebrovascular abnormalities in transgenic mice. ALZHEIMER'S DISEASE: VASCULAR ETIOLOGY AND PATHOLOGY, 977, 87-95.

Construction of a 3-Mb contig and partial transcript map of the central region of mouse chromosome 11
WATKINSCHOW, D. E., Douglas, K. R., Buckwalter, M. S., Probst, F. J., & Camper, S. A. (1997). Construction of a 3-Mb contig and partial transcript map of the central region of mouse chromosome 11. GENOMICS, 45(1), 147-157.

Genetic mapping of 21 genes on mouse chromosome 11 reveals disruptions in linkage conservation with human chromosome 5
WATKINSCHOW, D. E., Buckwalter, M. S., Newhouse, M. M., Lossie, A. C., Brinkmeier, M. L., & Camper, S. A. (1997). Genetic mapping of 21 genes on mouse chromosome 11 reveals disruptions in linkage conservation with human chromosome 5. GENOMICS, 40(1), 114-122.

A FRAMESHIFT MUTATION IN THE MOUSE ALPHA(1) GLYCINE RECEPTOR GENE (GLRA1) RESULTS IN PROGRESSIVE NEUROLOGICAL SYMPTOMS AND JUVENILE DEATH
Buckwalter, M. S., Cook, S. A., Davisson, M. T., White, W. F., & Camper, S. A. (1994). A FRAMESHIFT MUTATION IN THE MOUSE ALPHA(1) GLYCINE RECEPTOR GENE (GLRA1) RESULTS IN PROGRESSIVE NEUROLOGICAL SYMPTOMS AND JUVENILE DEATH. HUMAN MOLECULAR GENETICS, 3(11), 2025-2030.

A MISSENSE MUTATION IN THE GENE ENCODING THE ALPHA(1) SUBUNIT OF THE INHIBITORY GLYCINE RECEPTOR IN THE SPASMODIC MOUSE
Ryan, S. G., Buckwalter, M. S., LYNCH, J. W., Handford, C. A., Segura, L., & OCONNELL, P. (1994). A MISSENSE MUTATION IN THE GENE ENCODING THE ALPHA(1) SUBUNIT OF THE INHIBITORY GLYCINE RECEPTOR IN THE SPASMODIC MOUSE. NATURE GENETICS, 7(2), 131-135.

GENETIC-MAPPING AND EVALUATION OF CANDIDATE GENES FOR SPASMODIC, A NEUROLOGICAL MOUSE MUTATION WITH ABNORMAL STARTLE RESPONSE
Buckwalter, M. S., Testa, C. M., Noebels, J. L., & Camper, S. A. (1993). GENETIC-MAPPING AND EVALUATION OF CANDIDATE GENES FOR SPASMODIC, A NEUROLOGICAL MOUSE MUTATION WITH ABNORMAL STARTLE RESPONSE. GENOMICS, 17(2), 279-286.

LYSYL OXIDASE (LOX) MAPS BETWEEN GRL-1 AND ADRB-2 ON MOUSE CHROMOSOME-18
Lossie, A. C., Buckwalter, M. S., & Camper, S. A. (1993). LYSYL OXIDASE (LOX) MAPS BETWEEN GRL-1 AND ADRB-2 ON MOUSE CHROMOSOME-18. MAMMALIAN GENOME, 4(3), 177-178.

LOCALIZATION OF THE HUMAN CHROMOSOME-5Q GENES GABRA-1, GABRG-2, IL-4, IL-5, AND IRF-1 ON MOUSE CHROMOSOME-11
Buckwalter, M. S., Lossie, A. C., SCARLETT, L. M., & Camper, S. A. (1992). LOCALIZATION OF THE HUMAN CHROMOSOME-5Q GENES GABRA-1, GABRG-2, IL-4, IL-5, AND IRF-1 ON MOUSE CHROMOSOME-11. MAMMALIAN GENOME, 3(10), 604-607.

MOUSE CHROMOSOME-11
BUCHBERG, A. M., Buckwalter, M. S., & Camper, S. A. (1992). MOUSE CHROMOSOME-11. MAMMALIAN GENOME, 3, S162-S181.

LOCALIZATION OF THE PANHYPOPITUITARY DWARF MUTATION (DF) ON MOUSE CHROMOSOME-11 IN AN INTERSUBSPECIFIC BACKCROSS
Buckwalter, M. S., Katz, R. W., & Camper, S. A. (1991). LOCALIZATION OF THE PANHYPOPITUITARY DWARF MUTATION (DF) ON MOUSE CHROMOSOME-11 IN AN INTERSUBSPECIFIC BACKCROSS. GENOMICS, 10(3), 515-526.

Mouse chromosome 11.
BUCHBERG, A. M., Moskow, J. J., Buckwalter, M. S., & Camper, S. A. (1991). Mouse chromosome 11. Mammalian genome , 1, S158-91.

BACTERIOPHAGE-MU SITES REQUIRED FOR TRANSPOSITION IMMUNITY
Darzins, A., KENT, N. E., Buckwalter, M. S., & CASADABAN, M. J. (1988). BACTERIOPHAGE-MU SITES REQUIRED FOR TRANSPOSITION IMMUNITY. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 85(18), 6826-6830.