Professional Summary
Education & Certifications
- Board Certification: American Board of Internal Medicine, Pulmonary Disease (2008)
- Board Certification: American Board of Internal Medicine, Critical Care Medicine (2009)
- Medical Education: Tufts University School of Medicine (2002) MA
- Fellowship: Stanford University Pulmonary and Critical Care Fellowship (2009) CA
- Residency: Stanford University Internal Medicine Residency (2005) CA
- Internship: Stanford University Internal Medicine Residency (2003) CA
- Residency, Stanford University, Internal Medicine (2005)
- MPH, Boston University, Epidemiology (1996)
Honors & Awards
- K08 Awardee, NIH-NHLBI (8/2015)
- Parker B. Francis Fellow 2014, Parker B. Francis Foundation (2014-2017)
Publications
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Epstein-Barr virus-associated malignancies: epidemiologic patterns and etiologic implications
Hsu, J. L., & Glaser, S. L. (2000). Epstein-Barr virus-associated malignancies: epidemiologic patterns and etiologic implications. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 34(1), 27–53. -
Hodgkin's disease in Asians: incidence patterns and risk factors in population-based data
Glaser, S. L., & Hsu, J. L. (2002). Hodgkin's disease in Asians: incidence patterns and risk factors in population-based data. LEUKEMIA RESEARCH, 26(3), 261–269. -
Epstein-Barr virus and breast cancer: State of the evidence for viral carcinogenesis
Glaser, S. L., Hsu, J. L., & Gulley, M. L. (2004). Epstein-Barr virus and breast cancer: State of the evidence for viral carcinogenesis. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 13(5), 688–697. -
Understanding and Identifying Bias and Confounding in the Medical Literature
Hsu, J. L., Banerjee, D., & Kuschner, W. G. (2008). Understanding and Identifying Bias and Confounding in the Medical Literature. SOUTHERN MEDICAL JOURNAL, 101(12), 1240–45. -
One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System
Hsu, J. L., Siroka, A. M., Smith, M. W., Holodniy, M., & Meduri, G. U. (2011). One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 15(6), E382–E387. -
Diagnosing invasive fungal disease in critically ill patients
Hsu, J. L., Ruoss, S. J., Bower, N. D., Lin, M., Holodniy, M., & Stevens, D. A. (2011). Diagnosing invasive fungal disease in critically ill patients. CRITICAL REVIEWS IN MICROBIOLOGY, 37(4), 277–312. -
The diagnostic yield of CT-guided percutaneous lung biopsy in solid organ transplant recipients
Hsu, J. L., Kuschner, W. G., Paik, J., Bower, N., Guillamet, M. C. V., & Kothary, N. (2012). The diagnostic yield of CT-guided percutaneous lung biopsy in solid organ transplant recipients. CLINICAL TRANSPLANTATION, 26(4), 615–21. -
Potential for overuse of corticosteroids and vasopressin in septic shock.
Hsu, J. L., Liu, V., Patterson, A. J., Martin, G. S., Nicolls, M. R., & Russell, J. A. (2012). Potential for overuse of corticosteroids and vasopressin in septic shock. Critical Care (London, England), 16(5), 447. -
Racial/ethnic differences in breast cancer survival among San Francisco Bay Area women
Hsu, J. L., Glaser, S. L., & West, D. W. (1997). Racial/ethnic differences in breast cancer survival among San Francisco Bay Area women. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 89(17), 1311–1312. -
Absence of Epstein-Barr virus EBER-1 transcripts in an epidemiologically diverse group of breast cancers
Glaser, S. L., Ambinder, R. F., DiGiuseppe, J. A., Horn-Ross, P. L., & Hsu, J. L. (1998). Absence of Epstein-Barr virus EBER-1 transcripts in an epidemiologically diverse group of breast cancers. INTERNATIONAL JOURNAL OF CANCER, 75(4), 555–558. -
Vasopressin Compared with Norepinephrine Augments the Decline of Plasma Cytokine Levels in Septic Shock
Russell, J. A., Fjell, C., Hsu, J. L., Lee, T., Boyd, J., Thair, S., … Walley, K. R. (2013). Vasopressin Compared with Norepinephrine Augments the Decline of Plasma Cytokine Levels in Septic Shock. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 188(3), 356–64. -
Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus
Jiang, X., Hsu, J. L., Tian, W., Yuan, K., Olcholski, M., Perez, V. D. J., … Nicolls, M. R. (2013). Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. JOURNAL OF MOLECULAR MEDICINE-JMM, 91(9), 1081–93. -
Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia
Hsu, J. L., Khan, M. A., Sobel, R. A., Jiang, X., Clemons, K. V., Nguyen, T. T., … Nicolls, M. R. (2013). Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia. PLOS ONE, 8(10). -
Propofol infusion syndrome resuscitation with extracorporeal life support: a case report and review of the literature.
Mayette, M., Gonda, J., Hsu, J. L., & Mihm, F. G. (2013). Propofol infusion syndrome resuscitation with extracorporeal life support: a case report and review of the literature. Annals of Intensive Care, 3(1), 32-? -
Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles.
Jiang, X., Malkovskiy, A. V., Tian, W., Sung, Y. K., Sun, W., Hsu, J. L., … Nicolls, M. R. (2014). Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles. Biomaterials, 35(2), 803–13. -
Application of a non-amplification-based technology to detect invasive fungal pathogens
Hsu, J. L., Binkley, J., Clemons, K. V., Stevens, D. A., Nicolls, M. R., & Holodniy, M. (2014). Application of a non-amplification-based technology to detect invasive fungal pathogens. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 78(2), 137–40. -
Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock
Beraud, A.-S., Guillamet, C. V., Hammes, J. L., Meng, L., Nicolls, M. R., & Hsu, J. L. (2014). Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 347(4), 295–98. -
Effects of Iron Chelators on the Formation and Development of Aspergillus fumigatus Biofilm
Nazik, H., Penner, J. C., Ferreira, J. A., Haagensen, J. A. J., Cohen, K., Spormann, A. M., … Stevens, D. A. (2015). Effects of Iron Chelators on the Formation and Development of Aspergillus fumigatus Biofilm. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59(10), 6514–20. -
Targeted complement inhibition and microvasculature in transplants: a therapeutic perspective.
Khan, M. A., Hsu, J. L., Assiri, A. M., & Broering, D. C. (2015). Targeted complement inhibition and microvasculature in transplants: a therapeutic perspective. Clinical and Experimental Immunology. -
Microvascular injury after lung transplantation
Nicolls, M. R., Hsu, J. L., & Jiang, X. (2016). Microvascular injury after lung transplantation. CURRENT OPINION IN ORGAN TRANSPLANTATION, 21(3), 279–84. -
Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip.
Jothimuthu, P., Hsu, J. L., Chen, R., Inayathullah, M., Pothineni, V. R., Jan, A., … Nicolls, M. R. (2016). Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip. ChemNanoMat : Chemistry of Nanomaterials for Energy, Biology and More, 2(9), 904–910. -
Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip
Jothimuthu, P., Hsu, J. L., Chen, R., Inayathullah, M., Pothineni, V. R., Jan, A., … Nicolls, M. R. (2016). Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip. CHEMNANOMAT, 2(9), 904–10. -
Aspergillus-related pulmonary diseases in lung transplantation
Pasupneti, S., Manouvakhova, O., Nicolls, M. R., & Hsu, J. L. (2017). Aspergillus-related pulmonary diseases in lung transplantation. MEDICAL MYCOLOGY, 55(1), 96–102. -
Microhemorrhage-associated tissue iron enhances the risk forAspergillus fumigatusinvasion in a mouse model of airway transplantation.
Hsu, J. L., Manouvakhova, O. V., Clemons, K. V., Inayathullah, M., Tu, A. B., Sobel, R. A., … Nicolls, M. R. (2018). Microhemorrhage-associated tissue iron enhances the risk forAspergillus fumigatusinvasion in a mouse model of airway transplantation. Science Translational Medicine, 10(429). -
Pulmonary Infections in Immunocompromised Hosts: Clinical.
Vazquez Guillamet, C., Hsu, J. L., Dhillon, G., & Vazquez Guillamet, R. (2018). Pulmonary Infections in Immunocompromised Hosts: Clinical. Journal of Thoracic Imaging. -
Iron: an essential nutrient for Aspergillus fumigatus and a fulcrum for pathogenesis.
Matthaiou, E. I., Sass, G., Stevens, D. A., & Hsu, J. L. (2018). Iron: an essential nutrient for Aspergillus fumigatus and a fulcrum for pathogenesis. Current Opinion in Infectious Diseases, 31(6), 506–11. -
Erratum for Nazik et al., effects of iron chelators on the formation and development of Aspergillus fumigatus biofilm.
Nazik, H., Penner, J. C., Ferreira, J. A., Haagensen, J. A., Cohen, K., Spormann, A. M., … Stevens, D. A. (2015). Erratum for Nazik et al., effects of iron chelators on the formation and development of Aspergillus fumigatus biofilm. Antimicrobial Agents and Chemotherapy, 59(11), 7160. -
Effects of Iron Chelators on the Formation and Development of Aspergillus fumigatus Biofilm.
Nazik, H., Penner, J. C., Ferreira, J. A., Haagensen, J. A., Cohen, K., Spormann, A. M., … Stevens, D. A. (2015). Effects of Iron Chelators on the Formation and Development of Aspergillus fumigatus Biofilm. Antimicrobial Agents and Chemotherapy, 59(10), 6514–20. -
Differences in prevalence of ICU protocols between neurologic and non-neurologic patient populations
Billington, M. E., Seethala, R. R., Hou, P. C., Takhar, S. S., Askari, R., Aisiku, I. P., … Ondrush, J. (2019). Differences in prevalence of ICU protocols between neurologic and non-neurologic patient populations. JOURNAL OF CRITICAL CARE, 52, 63–67. -
Physiology of the Assisted Circulation in Cardiogenic Shock: A State-of-the-Art Perspective.
Guihaire, J., Haddad, F., Hoppenfeld, M., Amsallem, M., Christle, J. W., Owyang, C., … Hsu, J. L. (2020). Physiology of the Assisted Circulation in Cardiogenic Shock: A State-of-the-Art Perspective. The Canadian Journal of Cardiology, 36(2), 170–83. -
Machine learning algorithms to differentiate among pulmonary complications after hematopoietic cell transplant.
Sharifi, H., Lai, Y. K., Guo, H., Hoppenfeld, M., Guenther, Z. D., Johnston, L., … Hsu, J. L. (2020). Machine learning algorithms to differentiate among pulmonary complications after hematopoietic cell transplant. Chest. -
Hematopoietic Cell Transplantation Version 2.2020
Saad, A., de Lima, M., Anand, S., Bhatt, V. R., Bookout, R., Chen, G., … Pluchino, L. A. (2020). Hematopoietic Cell Transplantation Version 2.2020. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 18(5), 599–634. -
Thoracic epidural analgesia in a lung transplant patient with an activated partial thromboplastin time falsely elevated by C-reactive protein.
Simon, E. R., Hsu, J., Nwokeabia, D., Leong, M., & Keeyapaj, W. (2021). Thoracic epidural analgesia in a lung transplant patient with an activated partial thromboplastin time falsely elevated by C-reactive protein. Canadian Journal of Anaesthesia = Journal Canadien d'Anesthesie. -
Head-to-head Comparison of Qualitative Radiologist Assessment With Automated Quantitative Computed Tomography Analysis for Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplantation.
Sharifi, H., Guenther, Z. D., Leung, A. N., Johnston, L., Lai, Y. K., Hsu, J. L., & Guo, H. H. (2021). Head-to-head Comparison of Qualitative Radiologist Assessment With Automated Quantitative Computed Tomography Analysis for Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplantation. Journal of Thoracic Imaging. -
The Use of Factor Eight Inhibitor Bypass Activity (FEIBA) for the Treatment of Perioperative Hemorrhage in Left Ventricular Assist Device Implantation.
O'Donnell, C., Rodriguez, A. J., Madhok, J., Sharifi, H., Wang, H., O'Brien, C. G., … Hill, C. C. (2021). The Use of Factor Eight Inhibitor Bypass Activity (FEIBA) for the Treatment of Perioperative Hemorrhage in Left Ventricular Assist Device Implantation. Journal of Cardiothoracic and Vascular Anesthesia. -
THE SAFETY AND EFFICACY OF PERIOPERATIVE FEIBA AFTER LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION
ODonnell, C., Rodriguez, A., Madhok, J., Wang, H., Shad, R., Sharifi, H., … Hill, C. (2021). THE SAFETY AND EFFICACY OF PERIOPERATIVE FEIBA AFTER LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION. CRITICAL CARE MEDICINE. LIPPINCOTT WILLIAMS & WILKINS. -
From Mass to Flow: Emerging Sepsis Diagnostics Based on Flow Cytometry Analysis of Neutrophils.
Verdonk, F., Hsu, J. L., & Gaudilliere, B. (2021). From Mass to Flow: Emerging Sepsis Diagnostics Based on Flow Cytometry Analysis of Neutrophils. American Journal of Respiratory and Critical Care Medicine. -
Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease.
Ward, R. A., Aghaeepour, N., Bhattacharyya, R. P., Clish, C. B., Gaudilliere, B., Hacohen, N., … Vyas, J. M. (2021). Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease. Open Forum Infectious Diseases, 8(11), ofab483. -
The safety and tolerability of pirfenidone for bronchiolitis obliterans syndrome after hematopoietic cell transplant (STOP-BOS) trial.
Matthaiou, E. I., Sharifi, H., O'Donnell, C., Chiu, W., Owyang, C., Chatterjee, P., … Hsu, J. L. (2022). The safety and tolerability of pirfenidone for bronchiolitis obliterans syndrome after hematopoietic cell transplant (STOP-BOS) trial. Bone Marrow Transplantation. -
Graft-versus-host disease may cause pulmonary restriction, but not all restriction is graft-versus-host disease.
Sheshadri, A., Huang, H. J., Bashoura, L., Alousi, A. M., Alkhunaizi, M. A., Sharifi, H., & Hsu, J. L. (2022). Graft-versus-host disease may cause pulmonary restriction, but not all restriction is graft-versus-host disease. Blood Advances. -
Macrophage Lysosomal Alkalinization Drives Invasive Aspergillosis in a Mouse Cystic Fibrosis Model of Airway Transplantation.
Matthaiou, E. I., Chiu, W., Conrad, C., & Hsu, J. (2022). Macrophage Lysosomal Alkalinization Drives Invasive Aspergillosis in a Mouse Cystic Fibrosis Model of Airway Transplantation. Journal of Fungi (Basel, Switzerland), 8(7). -
Epidemiology of lower respiratory tract infections and community-acquired respiratory viruses in patients with bronchiolitis obliterans syndrome after hematopoietic cell transplant: a retrospective cohort study.
Epstein, D. J., Liang, E. C., Sharifi, H., Lai, Y. K., Arai, S., Graber-Naidich, A., … Hsu, J. L. (2022). Epidemiology of lower respiratory tract infections and community-acquired respiratory viruses in patients with bronchiolitis obliterans syndrome after hematopoietic cell transplant: a retrospective cohort study. Transplantation and Cellular Therapy. -
A value-based approach to optimize red blood cell transfusion in patients receiving extracorporeal membrane oxygenation.
Shudo, Y., Cheng, N., He, H., Rosenberg, C., Hiesinger, W., Hadhazy, E., … Woo, Y. J. (2022). A value-based approach to optimize red blood cell transfusion in patients receiving extracorporeal membrane oxygenation. Perfusion, 2676591221128138. -
NCCN Guidelines Insights: Hematopoietic Cell Transplantation, Version 3.2022.
Saad, A., Loren, A., Bolanos-Meade, J., Chen, G., Couriel, D., Di Stasi, A., … Pluchino, L. A. (2023). NCCN Guidelines Insights: Hematopoietic Cell Transplantation, Version 3.2022. Journal of the National Comprehensive Cancer Network : JNCCN, 21(2), 108–115. -
IMPACT OF C-REACTIVE PROTEIN ON ANTICOAGULATION MONITORING IN EXTRACORPOREAL MEMBRANE OXYGENATION
Madhok, J., ODonnell, C., Jin, J., Owyang, C., Weimer, J., Pashun, R., … Hsu, J. (2023). IMPACT OF C-REACTIVE PROTEIN ON ANTICOAGULATION MONITORING IN EXTRACORPOREAL MEMBRANE OXYGENATION. CRITICAL CARE MEDICINE. LIPPINCOTT WILLIAMS & WILKINS. -
Coronavirus Disease-2019 Pneumonia: Clinical Manifestations.
Sharifi, H., & Hsu, J. (2023). Coronavirus Disease-2019 Pneumonia: Clinical Manifestations. Clinics in Chest Medicine, 44(2), 227–237.
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