Ellen Yeh

Professional Education

Residency: Stanford Hospital and Clinics (2011) CA

Medical Education: Harvard Medical School (2008) MA

MD, Harvard Medical School, Medicine (2008)

PhD, Harvard Medical School, Biophysics (2006)

BA, Harvard University, Biochemical Sciences (2001)

Honors & Awards

Early Career Independence Award (DP5), NIH (2012-2017)

Career Award for Medical Scientists, Burroughs-Wellcome Fund (2012-2017)

Medical Scientist Training Program (MSTP), NIH (2001-2008)

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum
Yeh, E., & DeRisi, J. L. (2011). Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum. PLOS BIOLOGY, 9(8).

Immediate Incubation Reduces Indeterminate Results for QuantiFERON-TB Gold In-Tube Assay
Herrera, V., Yeh, E., Murphy, K., Parsonnet, J., & Banaei, N. (2010). Immediate Incubation Reduces Indeterminate Results for QuantiFERON-TB Gold In-Tube Assay. JOURNAL OF CLINICAL MICROBIOLOGY, 48(8), 2672-2676.

Real-Time PCR Testing for mecA Reduces Vancomycin Usage and Length of Hospitalization for Patients Infected with Methicillin-Sensitive Staphylococci
Nguyen, D. T., Yeh, E., Perry, S., Luo, R. F., Pinsky, B. A., & Banaei, N. (2010). Real-Time PCR Testing for mecA Reduces Vancomycin Usage and Length of Hospitalization for Patients Infected with Methicillin-Sensitive Staphylococci. JOURNAL OF CLINICAL MICROBIOLOGY, 48(3), 785-790.

Preferential Lower Respiratory Tract Infection in Swine-Origin 2009 A(H1N1) Influenza
Yeh, E., Luo, R. F., Dyner, Ll., Hong, D. K., Banaei, N., & Pinsky, B. A. (2010). Preferential Lower Respiratory Tract Infection in Swine-Origin 2009 A(H1N1) Influenza. CLINICAL INFECTIOUS DISEASES, 50(3), 391-394.

Hair Sheep Blood, Citrated or Defibrinated, Fulfills All Requirements of Blood Agar for Diagnostic Microbiology Laboratory Tests
Yeh, E., Pinsky, B. A., Banaei, N., & Baron, E. J. (2009). Hair Sheep Blood, Citrated or Defibrinated, Fulfills All Requirements of Blood Agar for Diagnostic Microbiology Laboratory Tests. PLOS ONE, 4(7).

Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases
Yeh, E., Blasiak, L. C., Koglin, A., Drennan, C. L., & Walsh, C. T. (2007). Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases. BIOCHEMISTRY, 46(5), 1284-1292.

Characterization of the aminocarboxycyclopropane-forming enzyme CmaC
Kelly, W. L., Boyne, M. T., Yeh, E., Vosburg, D. A., Galonic, D. P., & Walsh, C. T. (2007). Characterization of the aminocarboxycyclopropane-forming enzyme CmaC. BIOCHEMISTRY, 46(2), 359-368.

Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete
Ueki, M., Galonic, D. P., Vaillancourt, F. H., Garneau-Tsodikova, S., Yeh, E., & Walsh, C. T. (2006). Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. CHEMISTRY & BIOLOGY, 13(11), 1183-1191.

Nature's inventory of halogenation catalysts: Oxidative strategies predominate
Vaillancourt, F. H., Yeh, E., Vosburg, D. A., Garneau-Tsodikova, S., & Walsh, C. T. (2006). Nature's inventory of halogenation catalysts: Oxidative strategies predominate. CHEMICAL REVIEWS, 106(8), 3364-3378.

Flavin redox chemistry precedes substrate chlorination during the reaction of the flavin-dependent halogenase RebH
Yeh, E., Cole, L. J., Barr, E. W., Bollinger, J. M., Ballou, D. P., & Walsh, C. T. (2006). Flavin redox chemistry precedes substrate chlorination during the reaction of the flavin-dependent halogenase RebH. BIOCHEMISTRY, 45(25), 7904-7912.

Dichlorination of a pyrrolyl-S-carrier protein by FADH(2)-dependent halogenase PltA during pyoluteorin biosynthesis
Dorrestein, P. C., Yeh, E., Garneau-Tsodikova, S., Kelleher, N. L., & Walsh, C. T. (2005). Dichlorination of a pyrrolyl-S-carrier protein by FADH(2)-dependent halogenase PltA during pyoluteorin biosynthesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(39), 13843-13848.

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis
Vaillancourt, F. H., Yeh, E., Vosburg, D. A., O'Connor, S. E., & Walsh, C. T. (2005). Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis. NATURE, 436(7054), 1191-1194.

Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis
Yeh, E., Garneau, S., & Walsh, C. T. (2005). Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(11), 3960-3965.

Enhanced macrocyclizing activity of the thioesterase from tyrocidine synthetase in presence of nonionic detergent
Yeh, E., Lin, H. N., Clugston, S. L., Kohli, R. M., & Walsh, C. T. (2004). Enhanced macrocyclizing activity of the thioesterase from tyrocidine synthetase in presence of nonionic detergent. CHEMISTRY & BIOLOGY, 11(11), 1573-1582.

Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl-S-enzyme that cannot be elongated
Yeh, E., Kohli, R. M., Bruner, S. D., & Walsh, C. T. (2004). Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl-S-enzyme that cannot be elongated. CHEMBIOCHEM, 5(9), 1290-1293.