Biography
Dr. Sun received her medical degree from McMaster University. She completed her anesthesiology residency at the University of Ottawa and her Masters of Science in Epidemiology at the Harvard School of Public Health, followed by a clinical and research fellowship in cardiac anesthesia at the University of Toronto. She then joined the Division of Cardiac Anesthesiology at the University of Ottawa Heart Institute and was cross appointed as an ICES faculty member.
Dr. Sun’s areas of clinical focus are hemodynamic monitoring and heart failure. Her methodologic areas of focus are the conduct of population-based cohort studies using large healthcare databases; predictive analytics; sex and gender epidemiology; patient engagement; innovative methods for data processing and warehousing; and software and applications development. Her research leverages big data and digital technology to bridge key gaps in the delivery of care and outcomes for patients with heart failure and/or undergoing cardiovascular interventions, zooming in on sex/gender and personalized care. She holds several patents and collaborates with health authorities and policy makers to evaluate and report on models of cardiac healthcare delivery.
Dr. Sun is active in the scientific community. She sits on a number of US, Canadian and international editorial boards and scientific and grant review committees, and collaborates nationally and internationally on a variety of population health and data science initiatives. Her patient-centered research program aims to improve access to care and outcomes, focusing on personalized risk stratification and long-term, patient-defined outcomes. She has authored over 100 peer-reviewed papers and published in leading clinical journals including JAMA, JAMA Cardiology, JAMA Internal Medicine, Circulation, JACC, Diabetes Care, and Anesthesiology. Her research program has been well funded by the Canadian Institutes of Health Research (CIHR), the Heart and Stroke Foundation of Canada, and the Ontario Ministry of Health.
Professional Summary
Education & Certifications
- Board Certification: National Board of Echocardiography, Advanced Perioperative Transesophageal Echocardiography (2016)
- Fellowship: University of Toronto (2014) Canada
- Board Certification: Royal College of Physicians and Surgeons of Canada, Anesthesia (2013)
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- Masters of Science, Harvard University, Clinical Epidemiology (2013)
- Residency: University of Ottawa (2013) Canada
- Medical Education: McMaster University Michael G. DeGroote School of Medicine (2008) Canada
Administrative Appointments
- Chief, Division of Cardiothoracic Anesthesiology, Stanford University School of Medicine (2022 - Present)
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Publications
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Sex-based differences in referral of heart failure patients to outpatient clinics: a scoping review.
Chan, E., Rooprai, J., Rodger, J., Visintini, S., Rodger, N., Philip, S., … Sun, L. Y. (2022). Sex-based differences in referral of heart failure patients to outpatient clinics: a scoping review. ESC Heart Failure. -
The association between cancer diagnosis, care, and outcomes in 1 million patients hospitalized for acute pulmonary embolism.
Mai, A. S., Matetic, A., Elgendy, I. Y., Lopez-Mattei, J., Kotronias, R. A., Sun, L. Y., … Mamas, M. A. (2022). The association between cancer diagnosis, care, and outcomes in 1 million patients hospitalized for acute pulmonary embolism. International Journal of Cardiology. -
Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients With Incident Diabetes.
Sun, L. Y., Zghebi, S. S., Eddeen, A. B., Liu, P. P., Lee, D. S., Tu, K., … Mamas, M. A. (2022). Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients With Incident Diabetes. Diabetes Care. -
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Outcomes From Intraoperative Handovers of Anesthesia Care.
Jones, P. M., Sun, L. Y., & Brenner, M. J. (2022). Outcomes From Intraoperative Handovers of Anesthesia Care. JAMA, 328(18), 1869. -
Palliative Care Use in Patients With Acute Myocardial Infarction and Do-Not-Resuscitate Status From a Nationwide Inpatient Cohort.
Kobo, O., Moledina, S. M., Mohamed, M. O., Sinnarajah, A., Simon, J., Sun, L. Y., … Mamas, M. A. (2022). Palliative Care Use in Patients With Acute Myocardial Infarction and Do-Not-Resuscitate Status From a Nationwide Inpatient Cohort. Mayo Clinic Proceedings. -
Comparison of Multidimensional Frailty Instruments for Estimation of Long-term Patient-Centered Outcomes After Cardiac Surgery.
Sun, L. Y., Jabagi, H., Fang, J., & Lee, D. S. (2022). Comparison of Multidimensional Frailty Instruments for Estimation of Long-term Patient-Centered Outcomes After Cardiac Surgery. JAMA Network Open, 5(9), e2230959. -
Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States.
Raisi-Estabragh, Z., Kobo, O., Elbadawi, A., Velagapudi, P., Sharma, G., Bullock-Palmer, R. P., … Mamas, M. A. (2022). Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States. Journal of the American Heart Association, 11(19), e026432. -
Trends in glucose testing among individuals without diabetes in Ontario between 2010 and 2017: a population-based cohort study.
Chu, A., Shah, B. R., Rashid, M., Booth, G. L., Fazli, G. S., Tu, K., … Lee, D. S. (2022). Trends in glucose testing among individuals without diabetes in Ontario between 2010 and 2017: a population-based cohort study. CMAJ Open, 10(3), E772–E780. -
Relationship of frailty with excess mortality during the COVID-19 pandemic: a population-level study in Ontario, Canada.
Wijeysundera, H. C., Abdel-Qadir, H., Qiu, F., Manoragavan, R., Austin, P. C., Kapral, M. K., … Lee, D. S. (2022). Relationship of frailty with excess mortality during the COVID-19 pandemic: a population-level study in Ontario, Canada. Aging Clinical and Experimental Research, 34(10), 2557–2565. -
IGFBP7 as a preoperative predictor of congestive acute kidney injury after cardiac surgery.
MacMillan, Y. S., Mamas, M. A., & Sun, L. Y. (2022). IGFBP7 as a preoperative predictor of congestive acute kidney injury after cardiac surgery. Open Heart, 9(1). -
Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality.
Stickels, C. P., Nadarajah, R., Gale, C. P., Jiang, H., Sharkey, K. J., Gibbison, B., … Erhun, F. (2022). Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality. BMJ Open, 12(6), e059309. -
Prediction of acute kidney injury risk after cardiac surgery: using a hybrid machine learning algorithm.
Petrosyan, Y., Mesana, T. G., & Sun, L. Y. (2022). Prediction of acute kidney injury risk after cardiac surgery: using a hybrid machine learning algorithm. BMC Medical Informatics and Decision Making, 22(1), 137. -
Representation of patient diversity in anesthesia curricular materials.
Leir, S. A., Sun, L., & Fraser, A. (2022). Representation of patient diversity in anesthesia curricular materials. Canadian Journal of Anaesthesia = Journal Canadien d'Anesthesie. -
Establishing an interdisciplinary research team for cardio-oncology artificial intelligence informatics precision and health equity.
Brown, S.-A. A., Sparapani, R., Osinski, K., Zhang, J., Blessing, J., Cheng, F., … Olson, J. (2022). Establishing an interdisciplinary research team for cardio-oncology artificial intelligence informatics precision and health equity. American Heart Journal plus : Cardiology Research and Practice, 13. -
Missing the Goal With the 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization.
Ruel, M., Williams, A., Ouzounian, M., Sun, L., Légaré, J.-F. F., Poirier, P., … Arora, R. C. (2022). Missing the Goal With the 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. The Canadian Journal of Cardiology, 38(6), 705–708. -
A standardized definition for right ventricular failure in cardiac surgery patients.
Jabagi, H., Nantsios, A., Ruel, M., Mielniczuk, L. M., Denault, A. Y., & Sun, L. Y. (2022). A standardized definition for right ventricular failure in cardiac surgery patients. ESC Heart Failure, 9(3), 1542–1552. -
Derivation and validation of a clinical risk score to predict death among patients awaiting cardiac surgery in Ontario, Canada: a population-based study.
Sun, L. Y., Wijeysundera, H. C., Lee, D. S., van Diepen, S., Ruel, M., Eddeen, A. B., & Mesana, T. G. (2022). Derivation and validation of a clinical risk score to predict death among patients awaiting cardiac surgery in Ontario, Canada: a population-based study. CMAJ Open, 10(1), E173–E182. -
Patient Sex and Postoperative Outcomes after Inpatient Intraabdominal Surgery: A Population-based Retrospective Cohort Study.
He, J. W., Sun, L. Y., Wijeysundera, D., Vogt, K., & Jones, P. M. (2022). Patient Sex and Postoperative Outcomes after Inpatient Intraabdominal Surgery: A Population-based Retrospective Cohort Study. Anesthesiology, 136(4), 577–587. -
Association Between Handover of Anesthesiology Care and 1-Year Mortality Among Adults Undergoing Cardiac Surgery.
Sun, L. Y., Jones, P. M., Wijeysundera, D. N., Mamas, M. A., Bader Eddeen, A., & O'Connor, J. (2022). Association Between Handover of Anesthesiology Care and 1-Year Mortality Among Adults Undergoing Cardiac Surgery. JAMA Network Open, 5(2), e2148161. -
Drivers and outcomes of variation in surgical versus transcatheter aortic valve replacement in Ontario, Canada: a population-based study.
Miranda, R. N., Qiu, F., Manoragavan, R., Fremes, S., Lauck, S., Sun, L., … Wijeysundera, H. C. (2022). Drivers and outcomes of variation in surgical versus transcatheter aortic valve replacement in Ontario, Canada: a population-based study. Open Heart, 9(1). -
Addressing disparities of care in non-ST-segment elevation myocardial infarction patients without standard modifiable risk factors: insights from a nationwide cohort study.
Moledina, S. M., Rashid, M., Nolan, J., Nakao, K., Sun, L. Y., Velagapudi, P., … Mamas, M. A. (2022). Addressing disparities of care in non-ST-segment elevation myocardial infarction patients without standard modifiable risk factors: insights from a nationwide cohort study. European Journal of Preventive Cardiology, 29(7), 1084–1092. -
Derivation and validation of predictive indices for 30-day mortality after coronary and valvular surgery in Ontario, Canada.
Sun, L. Y., Chu, A., Tam, D. Y., Wang, X., Fang, J., Austin, P. C., … Lee, D. S. (2021). Derivation and validation of predictive indices for 30-day mortality after coronary and valvular surgery in Ontario, Canada. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 193(46), E1757–E1765. -
Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest.
Dafaalla, M., Rashid, M., Sun, L., Quinn, T., Timmis, A., Wijeysundera, H., … Mamas, M. A. (2022). Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. Resuscitation, 170, 327–334. -
Predictors, Treatments, and Outcomes of Do-Not-Resuscitate Status in Acute Myocardial Infarction Patients (from a Nationwide Inpatient Cohort Study).
Kobo, O., Moledina, S. M., Slawnych, M., Sinnarajah, A., Simon, J., Van Spall, H. G., … Mamas, M. A. (2021). Predictors, Treatments, and Outcomes of Do-Not-Resuscitate Status in Acute Myocardial Infarction Patients (from a Nationwide Inpatient Cohort Study). The American Journal of Cardiology, 159, 8–18. -
The Impact of the COVID-19 Pandemic on Cardiac Procedure Wait List Mortality in Ontario, Canada.
Tam, D. Y., Qiu, F., Manoragavan, R., Fremes, S. E., Hassan, A., Ko, D. T., … Wijeysundera, H. C. (2021). The Impact of the COVID-19 Pandemic on Cardiac Procedure Wait List Mortality in Ontario, Canada. The Canadian Journal of Cardiology, 37(10), 1547–1554. -
Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019.
Kobo, O., Khattak, S., Lopez-Mattei, J., Van Spall, H. G., Graham, M., Cheng, R. K., … Mamas, M. A. (2021). Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019. International Journal of Clinical Practice, 75(11), e14841. -
Impact of the admitting ward on care quality and outcomes in non-ST-segment elevation myocardial infarction: insights from a national registry.
Moledina, S. M., Shoaib, A., Sun, L. Y., Myint, P. K., Kotronias, R. A., Shah, B. N., … Mamas, M. A. (2022). Impact of the admitting ward on care quality and outcomes in non-ST-segment elevation myocardial infarction: insights from a national registry. European Heart Journal. Quality of Care & Clinical Outcomes, 8(6), 681–691. -
Derivation and validation of a clinical model to predict death or cardiac hospitalizations while on the cardiac surgery waitlist.
Sun, L. Y., Eddeen, A. B., Wijeysundera, H. C., Mamas, M. A., Tam, D. Y., & Mesana, T. G. (2021). Derivation and validation of a clinical model to predict death or cardiac hospitalizations while on the cardiac surgery waitlist. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 193(34), E1333–E1340. -
Impact of surgeon and anaesthesiologist sex on patient outcomes after cardiac surgery: a population-based study.
Sun, L. Y., Boet, S., Chan, V., Lee, D. S., Mesana, T. G., Bader Eddeen, A., & Etherington, C. (2021). Impact of surgeon and anaesthesiologist sex on patient outcomes after cardiac surgery: a population-based study. BMJ Open, 11(8), e051192. -
The association between cardiac intensive care unit mechanical ventilation volumes and in-hospital mortality.
Nandiwada, S., Islam, S., Jentzer, J. C., Miller, P. E., Fordyce, C. B., Lawler, P., … van Diepen, S. (2021). The association between cardiac intensive care unit mechanical ventilation volumes and in-hospital mortality. European Heart Journal. Acute Cardiovascular Care, 10(7), 797–805. -
Disability-free survival after major cardiac surgery: a population-based retrospective cohort study.
Sun, L. Y., Eddeen, A. B., & Mesana, T. G. (2021). Disability-free survival after major cardiac surgery: a population-based retrospective cohort study. CMAJ Open, 9(2), E384–E393. -
Derivation of Patient-Defined Adverse Cardiovascular and Noncardiovascular Events Through a Modified Delphi Process.
Sun, L. Y., Rodger, J., Duffett, L., Tulloch, H., Crean, A. M., Chong, A.-Y. Y., … Bilodeau, J. (2021). Derivation of Patient-Defined Adverse Cardiovascular and Noncardiovascular Events Through a Modified Delphi Process. JAMA Network Open, 4(1), e2032095. -
Predictors of cumulative cost for patients with severe aortic stenosis referred for surgical or transcatheter aortic valve replacement: a population-based study in Ontario, Canada.
Sunner, M., Qiu, F., Manoragavan, R., Roifman, I., Tam, D. Y., Fremes, S. C., … Wijeysundera, H. C. (2021). Predictors of cumulative cost for patients with severe aortic stenosis referred for surgical or transcatheter aortic valve replacement: a population-based study in Ontario, Canada. European Heart Journal. Quality of Care & Clinical Outcomes, 7(3), 265–272. -
Sex-specific temporal trends in ambulatory heart failure incidence, mortality and hospitalisation in Ontario, Canada from 1994 to 2013: a population-based cohort study.
Sun, L. Y., Mielniczuk, L. M., Liu, P. P., Beanlands, R. S., Chih, S., Davies, R., … Tu, J. V. (2020). Sex-specific temporal trends in ambulatory heart failure incidence, mortality and hospitalisation in Ontario, Canada from 1994 to 2013: a population-based cohort study. BMJ Open, 10(11), e044126. -
Response to the Comment on "Single Versus Multiple Arterial Revascularization in Patients With Reduced Renal Function Long-Term Outcome Comparisons in 23,406 CABG Patients From Ontario, Canada".
Hayatsu, Y., Ruel, M., & Sun, L. Y. (2021). Response to the Comment on "Single Versus Multiple Arterial Revascularization in Patients With Reduced Renal Function Long-Term Outcome Comparisons in 23,406 CABG Patients From Ontario, Canada". Annals of Surgery, 274(6), e824–e825. -
Implications of the ISCHEMIA trial on the practice of surgical myocardial revascularization.
Ruel, M., Sun, L. Y., Farkouh, M. E., & Gaudino, M. F. (2021). Implications of the ISCHEMIA trial on the practice of surgical myocardial revascularization. The Journal of Thoracic and Cardiovascular Surgery, 162(1), 90–99. -
Patients With Severely Reduced Ejection Fraction Undergoing Revascularization-Is Something Missing?-Reply.
Sun, L. Y., Gaudino, M., & Ruel, M. (2021). Patients With Severely Reduced Ejection Fraction Undergoing Revascularization-Is Something Missing?-Reply. JAMA Cardiology, 6(2), 242. -
Impact of physician's sex/gender on processes of care, and clinical outcomes in cardiac operative care: a systematic review.
Etherington, N., Deng, M., Boet, S., Johnston, A., Mansour, F., Said, H., … Sun, L. Y. (2020). Impact of physician's sex/gender on processes of care, and clinical outcomes in cardiac operative care: a systematic review. BMJ Open, 10(9), e037139. -
Derivation and Validation of a Clinical Model to Predict Intensive Care Unit Length of Stay After Cardiac Surgery.
Sun, L. Y., Bader Eddeen, A., Ruel, M., MacPhee, E., & Mesana, T. G. (2020). Derivation and Validation of a Clinical Model to Predict Intensive Care Unit Length of Stay After Cardiac Surgery. Journal of the American Heart Association, 9(21), e017847. -
Long-Term Survival After Surgical or Percutaneous Revascularization in Patients With Diabetes and Multivessel Coronary Disease.
Tam, D. Y., Dharma, C., Rocha, R., Farkouh, M. E., Abdel-Qadir, H., Sun, L. Y., … Lee, D. S. (2020). Long-Term Survival After Surgical or Percutaneous Revascularization in Patients With Diabetes and Multivessel Coronary Disease. Journal of the American College of Cardiology, 76(10), 1153–1164. -
Coronary Artery Disease in Patients With Cancer: It's Always the Small Pieces That Make the Bigger Picture.
Mamas, M. A., Brown, S.-A. A., & Sun, L. Y. (2020). Coronary Artery Disease in Patients With Cancer: It's Always the Small Pieces That Make the Bigger Picture. Mayo Clinic Proceedings, 95(9), 1819–1821. -
Trends in sex-based differences in outcomes following coronary artery bypass grafting in the United States between 2004 and 2015.
Mohamed, W., Mohamed, M. O., Hirji, S., Ouzounian, M., Sun, L. Y., Coutinho, T., … Mamas, M. A. (2020). Trends in sex-based differences in outcomes following coronary artery bypass grafting in the United States between 2004 and 2015. International Journal of Cardiology, 320, 42–48. -
Direct Implant of a Transcatheter Aortic Valve Prosthesis for Prosthetic Mitral Valve Endocarditis.
Hayatsu, Y., Dryden, A., Messika-Zeitoun, D., Sun, L. Y., Mesana, T., & Ruel, M. (2020). Direct Implant of a Transcatheter Aortic Valve Prosthesis for Prosthetic Mitral Valve Endocarditis. CJC Open, 2(4), 303–305. -
The Impact of Preoperative Risk on the Association between Hypotension and Mortality after Cardiac Surgery: An Observational Study.
Ristovic, V., de Roock, S., Mesana, T. G., van Diepen, S., & Sun, L. Y. (2020). The Impact of Preoperative Risk on the Association between Hypotension and Mortality after Cardiac Surgery: An Observational Study. Journal of Clinical Medicine, 9(7). -
Single Versus Multiple Arterial Revascularization in Patients With Reduced Renal Function: Long-term Outcome Comparisons in 23,406 CABG Patients From Ontario, Canada.
Hayatsu, Y., Ruel, M., Bader Eddeen, A., & Sun, L. (2022). Single Versus Multiple Arterial Revascularization in Patients With Reduced Renal Function: Long-term Outcome Comparisons in 23,406 CABG Patients From Ontario, Canada. Annals of Surgery, 275(3), 602–608. -
Age, Not Sex, Modifies the Effect of Frailty on Long-term Outcomes After Cardiac Surgery.
Sun, L. Y., Spence, S. D., Benton, S., Beanlands, R. S., Austin, P. C., Bader Eddeen, A., & Lee, D. S. (2022). Age, Not Sex, Modifies the Effect of Frailty on Long-term Outcomes After Cardiac Surgery. Annals of Surgery, 275(4), 800–806. -
Sex differences after coronary artery bypass grafting with a second arterial conduit.
Rubens, F. D., Wells, G. A., Coutinho, T., Eddeen, A. B., & Sun, L. Y. (2022). Sex differences after coronary artery bypass grafting with a second arterial conduit. The Journal of Thoracic and Cardiovascular Surgery, 163(2), 686–695.e10. -
Readmission rates following heart failure: a scoping review of sex and gender based considerations.
Hoang-Kim, A., Parpia, C., Freitas, C., Austin, P. C., Ross, H. J., Wijeysundera, H. C., … Rochon, P. A. (2020). Readmission rates following heart failure: a scoping review of sex and gender based considerations. BMC Cardiovascular Disorders, 20(1), 223. -
Incorporation of renal function in mortality risk assessment for pulmonary arterial hypertension.
Zelt, J. G., Hossain, A., Sun, L. Y., Mehta, S., Chandy, G., Davies, R. A., … Mielniczuk, L. M. (2020). Incorporation of renal function in mortality risk assessment for pulmonary arterial hypertension. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation, 39(7), 675–685. -
Long-term Outcomes in Patients With Severely Reduced Left Ventricular Ejection Fraction Undergoing Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting.
Sun, L. Y., Gaudino, M., Chen, R. J., Bader Eddeen, A., & Ruel, M. (2020). Long-term Outcomes in Patients With Severely Reduced Left Ventricular Ejection Fraction Undergoing Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting. JAMA Cardiology, 5(6), 631–641. -
Defining an Intraoperative Hypotension Threshold in Association with De Novo Renal Replacement Therapy after Cardiac Surgery.
Ngu, J. M., Jabagi, H., Chung, A. M., Boodhwani, M., Ruel, M., Bourke, M., & Sun, L. Y. (2020). Defining an Intraoperative Hypotension Threshold in Association with De Novo Renal Replacement Therapy after Cardiac Surgery. Anesthesiology, 132(6), 1447–1457. -
Preoperative Risk, Blood Pressure, and Acute Kidney Injury.
Sun, L. Y. (2020). Preoperative Risk, Blood Pressure, and Acute Kidney Injury. Anesthesiology, 132(3), 416–417. -
Renal insufficiency and severe coronary artery disease: should coronary artery bypass grafting, off-pump coronary artery bypass grafting or percutaneous coronary intervention be performed?
Hayatsu, Y., Ruel, M., & Sun, L. Y. (2019). Renal insufficiency and severe coronary artery disease: should coronary artery bypass grafting, off-pump coronary artery bypass grafting or percutaneous coronary intervention be performed? Current Opinion in Cardiology, 34(6), 645–649. -
Can Biomarkers Provide Right Ventricular-Specific Prognostication in the Perioperative Setting?
Jabagi, H., Ruel, M., & Sun, L. Y. (2020). Can Biomarkers Provide Right Ventricular-Specific Prognostication in the Perioperative Setting? Journal of Cardiac Failure, 26(9), 776–780. -
Sex Differences in Long-Term Survival After Major Cardiac Surgery: A Population-Based Cohort Study.
Johnston, A., Mesana, T. G., Lee, D. S., Eddeen, A. B., & Sun, L. Y. (2019). Sex Differences in Long-Term Survival After Major Cardiac Surgery: A Population-Based Cohort Study. Journal of the American Heart Association, 8(17), e013260. -
Prospective validation and refinement of the APPROACH cardiovascular surgical intensive care unit readmission score.
Verma, S., Southern, D. A., Raslan, I. R., Norris, C. M., Graham, M. M., Bagshaw, S. M., … van Diepen, S. (2019). Prospective validation and refinement of the APPROACH cardiovascular surgical intensive care unit readmission score. Journal of Critical Care, 54, 117–121. -
The Current Role of Viability Imaging to Guide Revascularization and Therapy Decisions in Patients With Heart Failure and Reduced Left Ventricular Function.
Kandolin, R. M., Wiefels, C. C., Mesquita, C. T., Chong, A.-Y. Y., Boland, P., Glineur, D., … Mielniczuk, L. M. (2019). The Current Role of Viability Imaging to Guide Revascularization and Therapy Decisions in Patients With Heart Failure and Reduced Left Ventricular Function. The Canadian Journal of Cardiology, 35(8), 1015–1029. -
Hypotension and Stroke in Cardiac Surgery: Reply.
Sun, L. Y., & Ruel, M. (2019). Hypotension and Stroke in Cardiac Surgery: Reply. Anesthesiology, 131(1), 217–218. -
The SYNTAX score according to diabetic status: What does it mean for the patient requiring myocardial revascularization?
Ruel, M., Sun, L. Y., & Gaudino, M. F. (2020). The SYNTAX score according to diabetic status: What does it mean for the patient requiring myocardial revascularization? The Journal of Thoracic and Cardiovascular Surgery, 159(3), 857–860. -
Ethnic differences in acute heart failure outcomes in Ontario.
Sun, L. Y., Kimmoun, A., Takagi, K., Liu, P. P., Bader Eddeen, A., & Mebazaa, A. (2019). Ethnic differences in acute heart failure outcomes in Ontario. International Journal of Cardiology, 291, 177–182. -
Post-Operative Calcium-Channel Blocker Use After Radial Artery Grafting: Do We Now Have a Definitive Answer?
Ruel, M., & Sun, L. Y. (2019). Post-Operative Calcium-Channel Blocker Use After Radial Artery Grafting: Do We Now Have a Definitive Answer? Journal of the American College of Cardiology, 73(18), 2307–2309. -
Biomarkers in the Diagnosis, Management, and Prognostication of Perioperative Right Ventricular Failure in Cardiac Surgery-Are We There Yet?
Jabagi, H., Mielniczuk, L. M., Liu, P. P., Ruel, M., & Sun, L. Y. (2019). Biomarkers in the Diagnosis, Management, and Prognostication of Perioperative Right Ventricular Failure in Cardiac Surgery-Are We There Yet? Journal of Clinical Medicine, 8(4). -
Utility of Novel Cardiorenal Biomarkers in the Prediction and Early Detection of Congestive Kidney Injury Following Cardiac Surgery.
Zelt, J. G., Mielniczuk, L. M., Liu, P. P., Dupuis, J.-Y. Y., Chih, S., Akbari, A., & Sun, L. Y. (2018). Utility of Novel Cardiorenal Biomarkers in the Prediction and Early Detection of Congestive Kidney Injury Following Cardiac Surgery. Journal of Clinical Medicine, 7(12). -
Genetics, coronary artery disease, and myocardial revascularization: will novel genetic risk scores bring new answers?
Hui, S. K., Sun, L., & Ruel, M. (2018). Genetics, coronary artery disease, and myocardial revascularization: will novel genetic risk scores bring new answers? Indian Journal of Thoracic and Cardiovascular Surgery, 34(Suppl 3), 213–221. -
Disability-free survival after coronary artery bypass grafting in women and men with heart failure.
Sun, L. Y., Tu, J. V., Lee, D. S., Beanlands, R. S., Ruel, M., Austin, P. C., … Liu, P. P. (2018). Disability-free survival after coronary artery bypass grafting in women and men with heart failure. Open Heart, 5(2), e000911. -
The Effect of Preoperative Anemia on Patients Undergoing Cardiac Surgery: A Propensity-Matched Analysis.
Jabagi, H., Boodhwani, M., Tran, D. T., Sun, L., Wells, G., & Rubens, F. D. (2019). The Effect of Preoperative Anemia on Patients Undergoing Cardiac Surgery: A Propensity-Matched Analysis. Seminars in Thoracic and Cardiovascular Surgery, 31(2), 157–163. -
Genetics of coronary artery disease: should they impact the choice of revascularization?
Hui, S. K., Lindale, E., Sun, L., & Ruel, M. (2018). Genetics of coronary artery disease: should they impact the choice of revascularization? Current Opinion in Cardiology, 33(6), 605–612. -
Sex-Specific Trends in Incidence and Mortality for Urban and Rural Ambulatory Patients with Heart Failure in Eastern Ontario from 1994 to 2013.
Sun, L. Y., Tu, J. V., Sherrard, H., Rodger, N., Coutinho, T., Turek, M., … Mielniczuk, L. M. (2018). Sex-Specific Trends in Incidence and Mortality for Urban and Rural Ambulatory Patients with Heart Failure in Eastern Ontario from 1994 to 2013. Journal of Cardiac Failure, 24(9), 568–574. -
Pivotal contemporary trials of percutaneous coronary intervention vs. coronary artery bypass grafting: a surgical perspective.
Ngu, J. M., Sun, L. Y., & Ruel, M. (2018). Pivotal contemporary trials of percutaneous coronary intervention vs. coronary artery bypass grafting: a surgical perspective. Annals of Cardiothoracic Surgery, 7(4), 527–532. -
Association of Frailty and Long-Term Survival in Patients Undergoing Coronary Artery Bypass Grafting.
Tran, D. T., Tu, J. V., Dupuis, J.-Y. Y., Bader Eddeen, A., & Sun, L. Y. (2018). Association of Frailty and Long-Term Survival in Patients Undergoing Coronary Artery Bypass Grafting. Journal of the American Heart Association, 7(15). -
Sex differences in outcomes of heart failure in an ambulatory, population-based cohort from 2009 to 2013.
Sun, L. Y., Tu, J. V., Coutinho, T., Turek, M., Rubens, F. D., McDonnell, L., … Mielniczuk, L. M. (2018). Sex differences in outcomes of heart failure in an ambulatory, population-based cohort from 2009 to 2013. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 190(28), E848–E854. -
Prevalence and Long-Term Survival After Coronary Artery Bypass Grafting in Women and Men With Heart Failure and Preserved Versus Reduced Ejection Fraction.
Sun, L. Y., Tu, J. V., Bader Eddeen, A., & Liu, P. P. (2018). Prevalence and Long-Term Survival After Coronary Artery Bypass Grafting in Women and Men With Heart Failure and Preserved Versus Reduced Ejection Fraction. Journal of the American Heart Association, 7(12). -
Defining an Intraoperative Hypotension Threshold in Association with Stroke in Cardiac Surgery.
Sun, L. Y., Chung, A. M., Farkouh, M. E., van Diepen, S., Weinberger, J., Bourke, M., & Ruel, M. (2018). Defining an Intraoperative Hypotension Threshold in Association with Stroke in Cardiac Surgery. Anesthesiology, 129(3), 440–447. -
The State of Affairs for Cardiovascular Health Research in Indigenous Women in Canada: A Scoping Review.
Prince, S. A., McDonnell, L. A., Turek, M. A., Visintini, S., Nahwegahbow, A., Kandasamy, S., … Coutinho, T. (2018). The State of Affairs for Cardiovascular Health Research in Indigenous Women in Canada: A Scoping Review. The Canadian Journal of Cardiology, 34(4), 437–449. -
Trends in Pulmonary Function Testing Before Noncardiothoracic Surgery.
Sun, L. Y., Gershon, A. S., Ko, D. T., Thilen, S. R., Yun, L., Beattie, W. S., & Wijeysundera, D. N. (2015). Trends in Pulmonary Function Testing Before Noncardiothoracic Surgery. JAMA Internal Medicine, 175(8), 1410–2. -
The association between tracheostomy and sternal wound infection in postoperative cardiac surgery patients.
Sun, L., Boodhwani, M., Baer, H., & McDonald, B. (2013). The association between tracheostomy and sternal wound infection in postoperative cardiac surgery patients. Canadian Journal of Anaesthesia = Journal Canadien d'Anesthesie, 60(7), 684–91. -
Management of Challenging Cardiopulmonary Bypass Separation.
Monaco, F., Di Prima, A. L., Kim, J. H., Plamondon, M.-J. J., Yavorovskiy, A., Likhvantsev, V., … Wang, C. Y. (2020). Management of Challenging Cardiopulmonary Bypass Separation. Journal of Cardiothoracic and Vascular Anesthesia, 34(6), 1622–1635. -
Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery.
Sun, L. Y., Wijeysundera, D. N., Tait, G. A., & Beattie, W. S. (2015). Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery. Anesthesiology, 123(3), 515–23. -
Mean transit time as an index of cerebral perfusion pressure in experimental systemic hypotension.
Murphy, M. J., Tichauer, K. M., Sun, L., Chen, X., & Lee, T.-Y. Y. (2011). Mean transit time as an index of cerebral perfusion pressure in experimental systemic hypotension. Physiological Measurement, 32(4), 395–405. -
Statins and SARS-CoV-2 Infection: Results of a Population-Based Prospective Cohort Study of 469 749 Adults From 2 Canadian Provinces.
McAlister, F. A., Wang, T., Wang, X., Chu, A., Goodman, S. G., van Diepen, S., … Lee, D. S. (2021). Statins and SARS-CoV-2 Infection: Results of a Population-Based Prospective Cohort Study of 469 749 Adults From 2 Canadian Provinces. Journal of the American Heart Association, 10(21), e022330. -
Long-Term Outcomes in Patients With Ischemic Cardiomyopathy: Comparative Effectiveness of Coronary Artery Bypass Grafting versus Percutaneous Coronary Intervention
Sun, L. Y., Chen, R. J., Tu, J., Bader Eddeen, A., & Ruel, M. (2018). Long-Term Outcomes in Patients With Ischemic Cardiomyopathy: Comparative Effectiveness of Coronary Artery Bypass Grafting versus Percutaneous Coronary Intervention. CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. -
CKD-Associated Cardiovascular Mortality in the United States: Temporal Trends From 1999 to 2020.
Kobo, O., Abramov, D., Davies, S., Ahmed, S. B., Sun, L. Y., Mieres, J. H., … Mamas, M. A. (2023). CKD-Associated Cardiovascular Mortality in the United States: Temporal Trends From 1999 to 2020. Kidney Medicine, 5(3), 100597. -
Derivation and validation of pragmatic clinical models to predict hospital length of stay after cardiac surgery in Ontario, Canada: a population-based cohort study.
Fottinger, A., Eddeen, A. B., Lee, D. S., Woodward, G., & Sun, L. Y. (2023). Derivation and validation of pragmatic clinical models to predict hospital length of stay after cardiac surgery in Ontario, Canada: a population-based cohort study. CMAJ Open, 11(1), E180–E190. -
Commentary: "Multimodality advanced cardiovascular and molecular imaging for early detection and monitoring of cancer therapy-associated cardiotoxicity and the role of artificial intelligence and big data".
Sun, L. Y., Echefu, G., Doshi, K., Roberts, M. L., Hamid, A., Cheng, R. K., … Brown, S.-A. A. (2023). Commentary: "Multimodality advanced cardiovascular and molecular imaging for early detection and monitoring of cancer therapy-associated cardiotoxicity and the role of artificial intelligence and big data". Frontiers in Cardiovascular Medicine, 10, 982028. -
Outcomes of ST elevation myocardial infarction in patients with cancer; a nationwide study.
Dafaalla, M., Abdel-Qadir, H., Gale, C. P., Sun, L., López-Fernández, T., Miller, R. J., … Mamas, M. A. (2023). Outcomes of ST elevation myocardial infarction in patients with cancer; a nationwide study. European Heart Journal. Quality of Care & Clinical Outcomes. -
Population Study of Sex-Based Outcomes After Surgical Aortic Valve Replacement.
Rubens, F. D., Clarke, A. E., Lee, D. S., Wells, G. A., & Sun, L. Y. (2023). Population Study of Sex-Based Outcomes After Surgical Aortic Valve Replacement. CJC Open, 5(3), 220–229. -
Ethnic Disparities in ST-Segment Elevation Myocardial Infarction Outcomes and Processes of Care in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: A Nationwide Cohort Study.
Weight, N., Moledina, S., Sun, L., Kragholm, K., Freeman, P., Diaz-Arocutipa, C., … Mamas, M. A. (2023). Ethnic Disparities in ST-Segment Elevation Myocardial Infarction Outcomes and Processes of Care in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: A Nationwide Cohort Study. Angiology, 33197231182555. -
Trends In ST-elevation Myocardial Infarction Hospitalisation Among Young Adults: A Binational Analysis.
Moledina, S. M., Matetic, A., Weight, N., Rashid, M., Sun, L., Fischman, D. L., … Mamas, M. A. (2023). Trends In ST-elevation Myocardial Infarction Hospitalisation Among Young Adults: A Binational Analysis. European Heart Journal. Quality of Care & Clinical Outcomes. -
Impact of the COVID-19 Pandemic on Diabetes-Related Cardiovascular Mortality in the United States.
Bashar, H., Kobo, O., Khunti, K., Sun, L. Y., Rutter, M. K., Chew, N. W., … Mamas, M. A. (2023). Impact of the COVID-19 Pandemic on Diabetes-Related Cardiovascular Mortality in the United States. Journal of the American Heart Association, e028896. -
Socioeconomic disparities in the management and outcomes of acute myocardial infarction.
Weight, N., Moledina, S., Volgman, A. S., Bagur, R., Wijeysundera, H. C., Sun, L. Y., … Mamas, M. A. (2023). Socioeconomic disparities in the management and outcomes of acute myocardial infarction. Heart (British Cardiac Society). -
Outcomes Among Patients Hospitalized With Non-COVID-19 Conditions Before and During the COVID-19 Pandemic in Alberta and Ontario, Canada.
McAlister, F. A., Chu, A., Qiu, F., Dong, Y., van Diepen, S., Youngson, E., … Wijeysundera, H. C. (2023). Outcomes Among Patients Hospitalized With Non-COVID-19 Conditions Before and During the COVID-19 Pandemic in Alberta and Ontario, Canada. JAMA Network Open, 6(7), e2323035. -
STICH3C: Rationale and Study Protocol.
Fremes, S. E., Marquis-Gravel, G., Gaudino, M. F., Jolicoeur, E. M., Bédard, S., Masterson Creber, R., … Rouleau, J.-L. L. (2023). STICH3C: Rationale and Study Protocol. Circulation. Cardiovascular Interventions, 16(8), e012527. -
Association between Surgeon/anesthesiologist Sex Discordance and One-year Mortality Among Adults Undergoing Noncardiac Surgery: A Population-based Retrospective Cohort Study.
Etherington, C., Boet, S., Chen, I., Duffy, M., Mamas, M. A., Eddeen, A. B., … Sun, L. Y. (2023). Association between Surgeon/anesthesiologist Sex Discordance and One-year Mortality Among Adults Undergoing Noncardiac Surgery: A Population-based Retrospective Cohort Study. Annals of Surgery. -
Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study.
Zghebi, S. S., Rutter, M. K., Sun, L. Y., Ullah, W., Rashid, M., Ashcroft, D. M., … Mamas, M. A. (2023). Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study. PloS One, 18(10), e0293314. -
Spontaneous Coronary Artery Dissection Across the Health Care Pathway: A National, Multicenter, Patient-Informed Investigation.
Bouchard, K., Lalande, K., Coutinho, T., Mulvagh, S., Pacheco, C., Liu, S., … Tulloch, H. (2023). Spontaneous Coronary Artery Dissection Across the Health Care Pathway: A National, Multicenter, Patient-Informed Investigation. Journal of the American Heart Association, e032141. -
Derivation and validation of predictive indices for cardiac readmission after coronary and valvular surgery - A multicenter study
Sun, L. Y., Chu, A., Tam, D. Y., Wang, X., Fang, J., Austin, P. C., … Lee, D. S. (2023). Derivation and validation of predictive indices for cardiac readmission after coronary and valvular surgery - A multicenter study. AMERICAN HEART JOURNAL PLUS: CARDIOLOGY RESEARCH AND PRACTICE, 28. -
Team principles for successful interdisciplinary research teams
Brown, S.-A., Sparapani, R., Osinski, K., Zhang, J., Blessing, J., Cheng, F., … Olson, J. (2023). Team principles for successful interdisciplinary research teams. AMERICAN HEART JOURNAL PLUS: CARDIOLOGY RESEARCH AND PRACTICE, 32. -
Derivation and validation of predictive indices for cardiac readmission after coronary and valvular surgery - A multicenter study.
Sun, L. Y., Chu, A., Tam, D. Y., Wang, X., Fang, J., Austin, P. C., … Lee, D. S. (2023). Derivation and validation of predictive indices for cardiac readmission after coronary and valvular surgery - A multicenter study. American Heart Journal plus : Cardiology Research and Practice, 28, 100285. -
Team principles for successful interdisciplinary research teams.
Brown, S.-A. A., Sparapani, R., Osinski, K., Zhang, J., Blessing, J., Cheng, F., … Olson, J. (2023). Team principles for successful interdisciplinary research teams. American Heart Journal plus : Cardiology Research and Practice, 32, 100306. -
Outcomes and Discriminatory Accuracy of the CHA2DS2VASc Score in Atrial Fibrillation and Cancer.
Ullah, W., DiMeglio, M., Frisch, D. R., Bagur, R., Sun, L. Y., Fischman, D. L., … Mamas, M. A. (2023). Outcomes and Discriminatory Accuracy of the CHA2DS2VASc Score in Atrial Fibrillation and Cancer. JACC. Advances, 2(8), 100609. -
Artificial Intelligence in Perioperative Care: Opportunities and Challenges.
Han, L., Char, D. S., & Aghaeepour, N. (2024). Artificial Intelligence in Perioperative Care: Opportunities and Challenges. Anesthesiology, 141(2), 379–387. -
Like Mother, Like Daughter: A Case of Peripartum Spontaneous Coronary Artery Dissection.
Yu, S., Dhawan, R., Kenny, E. S., Banayan, J. M., Bodmer, N. J., Sun, L. Y., & Oakes, D. (2024). Like Mother, Like Daughter: A Case of Peripartum Spontaneous Coronary Artery Dissection. Journal of Cardiothoracic and Vascular Anesthesia. -
Perioperative handovers-lost in transition.
Bodmer, N. J., Jones, P. M., & Sun, L. Y. (2024). Perioperative handovers-lost in transition. Canadian Journal of Anaesthesia = Journal Canadien d'Anesthesie. -
Through the Center of Cardiovascular Research: My Journey with Big Data and Bioengineering: The 2024 J. Earl Wynands Lecture (Society of Cardiovascular Anesthesiologists).
Sun, L. Y. (2024). Through the Center of Cardiovascular Research: My Journey with Big Data and Bioengineering: The 2024 J. Earl Wynands Lecture (Society of Cardiovascular Anesthesiologists). Anesthesia and Analgesia. -
STRIVE pilot trial: a protocol for a multicentre pragmatic internal pilot randomised controlled trial of Structured TRaining to Improve fitness in a Virtual Environment (STRIVE) before surgery.
McIsaac, D. I., Tandon, P., Kidd, G., Branje, K., Hladkowicz, E., Hallet, J., … Gillis, C. (2024). STRIVE pilot trial: a protocol for a multicentre pragmatic internal pilot randomised controlled trial of Structured TRaining to Improve fitness in a Virtual Environment (STRIVE) before surgery. BMJ Open, 14(11), e093710. -
The Association of Echocardiographically Measured Donor Left Ventricular Mass and 1-Year Outcomes After Heart Transplantation.
O'Donnell, C., Tapaskar, N., Sanchez, P. A., Wayda, B., Santana, E. J., Pulgrossi, R. C., … Khush, K. K. (2024). The Association of Echocardiographically Measured Donor Left Ventricular Mass and 1-Year Outcomes After Heart Transplantation. JACC. Heart Failure. -
Addressing gender disparities in academic anesthesiology through structural change.
Flexman, A. M., Sun, L. Y., & Lorello, G. R. (2024). Addressing gender disparities in academic anesthesiology through structural change. Canadian Journal of Anaesthesia = Journal Canadien d'Anesthesie. -
Long-term Time-specific Sex Differences in Survival and Major Adverse Cardiovascular Events Following Surgical versus Percutaneous Revascularization
O'Donnell, C., Fielding-Singh, V., Rios-Monterrosa, J., & Sun, L. (2024). Long-term Time-specific Sex Differences in Survival and Major Adverse Cardiovascular Events Following Surgical versus Percutaneous Revascularization. ANESTHESIA AND ANALGESIA. LIPPINCOTT WILLIAMS & WILKINS. -
Association of Kidney Function With Inpatient Mortality and Morbidity After Cardiac Surgery.
Fielding-Singh, V., Vanneman, M. W., Hong, T., Sun, L. Y., Morris, A. M., Chertow, G. M., & Lin, E. (2024). Association of Kidney Function With Inpatient Mortality and Morbidity After Cardiac Surgery. Annals of Thoracic Surgery Short Reports, 2(4), 877–883.
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Outcomes From Intraoperative Handovers of Anesthesia Care.
Practice Locations
SHC- Anesthesia (300P) Stanford, CA
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Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
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