As a practicing gastroenterologist and researcher specializing in inflammatory bowel disease (IBD), a disease without medical cure and whose pathogenesis is incompletely understood, I am keenly aware of the resultant limitations and risks of existing IBD therapies. It is precisely this need—the need to offer patients improved treatment options by better understanding the underlying causes of IBD and its impact on patients—that motivates me and is a focus of my research. With a unique background with formal training in Biodesign (medical technology assessment and development) and postdoctoral training in translational immunology, I am particularly interested in developing and applying novel solutions to alleviate intestinal inflammatory conditions.

There are two primary and overlapping emphases of my research, both of which are driven and united by needs-based innovation and translational potential:

(1) Understanding the microenvironment of the inflamed versus normal gut in order to identify better therapeutic targets for people with immune-¬mediated GI disorders. Here, our investigations include understanding the influence and interactions of pharmacologic and dietary interventions on gut microbiome/metabolomic changes and the host immune response. In the context of providing patients with new understanding and solutions for their disease, I have led and advised on the design of both pilot and large clinical trials (including new FDA approved therapies) for anti-inflammatory therapies;

(2) Applying novel approaches and technologies (including natural language processing, computer vision, and reinforcement learning) to identify and address unmet clinical needs. In this area we have ongoing and published efforts in my lab to validate and develop solutions to pressing clinical needs. We have developed/led new drug delivery technologies with a multidisciplinary team that have shown strong potential in ongoing human IBD clinical trials. My lab has utilized both supervised and unsupervised approaches to analyze social media discourse and unstructured data sets for identifying patient needs that are rarely addressed in clinical settings. We have gained insights into patient perceptions around preventative health interventions, such as health screening and diet, including the dearth of evidence-based dietary recommendations to treat IBD (despite strong patient desire for solutions in this domain).

Professional Summary

Professional Education
  • Board Certification: American Board of Internal Medicine, Gastroenterology (2014)
  • Board Certification: American Board of Internal Medicine, Internal Medicine (2010)
  • Fellowship: Stanford Hospital and Clinics (2014) CA
  • Fellowship, Mayo Clinic, Rochester, MN (Crohn's & Colitis Foundation Visiting IBD Fellow Program), Inflammatory Bowel Disease (2013)
  • Fellowship: Stanford Biodesign Program (2011) CA
  • Residency: Stanford University School of Medicine (2010) CA
  • Medical Education: University of California San Francisco (2007) CA
  • BA, Harvard University (1997)

Administrative Appointments
  • Director of Digital Health and Innovation, Division of Gastroenterology & Hepatology Stanford University School of Medicine (2019 - Present)


Clinical Trials

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Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Practice Locations

Inflammatory Bowel Disease (IBD) Program Redwood City, CA
Redwood City, CA

420 Broadway Street, Pavilion D, 2nd Floor

Redwood City , CA 94063

(650) 736-5555

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General Gastroenterology Clinic Redwood City, CA
Redwood City, CA

420 Broadway Street, Pavilion D, 2nd Floor

Redwood City , CA 94063

(650) 736-5555

Make An Appointment More Clinic Information » Getting Here »

Digestive Health Center in Redwood City Redwood City, CA
Redwood City, CA

420 Broadway Street, Pavilion D, 2nd Floor

Redwood City , CA 94063

(650) 736-5555

Make An Appointment More Clinic Information » Getting Here »

Patient Ratings

(20 Ratings)

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Patient Reviews

(23 reviews)

Thank you doctors and staffs.
Dr. Sinha is always available to answer questions; I always feel if I have a problem he will work with me to find a solution.
Very excellent -
Dr. Sidhartha Ranjit was very impressive - confident & competent! Best of all he was not one time looking at a screen of ANY type!
Dr. Sinha was very attentive. He took time to answer our questions. He showed patience, care and respect.
Since I've been under treatment for a while, Dr. Sinha went through the visit/check-up quickly. I would have appreciated going over details of my condition regardless of the fact that it is routine.
The best.
Dr. Sinha was absolutely great, provide terrific information and took the time to understand my problem, and developed a positive path forward!
Always very clean & shows concern & expertise on how his plan & rec. fit into the total healthcare plan.
Appreciated the time doctor spend with me in office reviewing my case.
Dr. Sidhartha is a excellent doctor and provider.
More structure for future care is needed.
This was the best part. My doctor was great. But it's hard to reach him now that I'm out of my appointment.
Excellent care provider.
Dr. Sinha is wonderful very caring & thorough.
I love him! He is truly concerned about the direction my care needs to go. Trying an experiment now.
Not only Dr. Sinha but an intern doctor who interviewed me was informative and helpful with new information, to me, to help manage my condition "FODMAP" for a food guide.
Dr. Sinha found answers we have about my husband's health.
Dr. Sinha is one of the most knowledgeable & courteous doctors I've ever seen.
I was very happy with Dr. Sinha. He made me feel totally comfortable & at ease, and he was very easy to talk to.
All info fax was not in chart both times.
Both my husband and I were very impressed with Dr. Sinhas' thoroughness and compassion with my condition.
He did not give any written summary of appointment - Leaving me... only.

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