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Symptoms of ALS
What are the symptoms of amyotrophic lateral sclerosis (ALS)?
The first sign of ALS is often weakness in one leg, one hand, the face, or the tongue. The weakness slowly spreads to both arms and both legs. This happens because as the motor neurons slowly die, they stop sending signals to the muscles. So the muscles don't have anything telling them to move. Over time, with no signals from the motor neurons telling the muscles to move, the muscles get weaker and smaller.
Over time, ALS also causes:
- Muscle twitching.
- Trouble using your hands and fingers to do tasks.
- Problems with speaking, swallowing, eating, walking, and breathing.
- Problems with memory, thinking, and changes in personality. But these are not common.
ALS doesn't cause numbness, tingling, or loss of feeling.
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.