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There are no specific treatments available for Corticobasal Degeneration (CBD). Drugs such as clonazepam may help with myoclonus, however, and occupational, physical, and speech therapy can help in managing the disabilities associated with this disease. Sometimes Botox® can be helpful for dystonia. The symptoms of the disease often do not respond to Parkinson's medications or other drugs, but may be used if there is a modest benefit.