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Treatments for Peyronie's Disease
How is Peyronie's disease treated?
Peyronie's disease rarely gets better on its own. For men who have a slight curve that isn't getting worse and who have good erectile function, treatment usually is not needed. But if pain is a problem, or if the curve is getting worse and interfering with your sexual activity, then getting treatment may help. And early treatment during the acute phase may also work better than waiting until you're in the chronic phase.
If your doctor is a primary care doctor, he or she may refer you to a urologist.
Most men are able to remain sexually active. Counseling can help couples maintain an active sexual life.
Medicines may help treat pain and reduce how much the penis curves. They include:
- NSAIDS such as ibuprofen (Advil) or naproxen (Aleve) for pain.
- Pentoxifylline, a combination of vitamin E and colchicine, or carnitine to reduce scarring. These are oral medicines (pills).
- Collagenase, interferon, and verapamil to reduce scarring. These are given as shots into the scar tissue.
There is not much evidence from studies showing how well any of these medicines work to heal the scarring and reduce the curve.
Surgery is only considered for men who have severe pain, a severely curved penis, or sexual dysfunction related to Peyronie's disease. Surgical options include removing the scar tissue or shortening the unaffected side of the penis (plication).
In some cases, a penile prosthesis may be used to help keep an erection during intercourse.
Male Reproductive Medicine and Surgery Program
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