Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

COVID-19 Updates:      COVID-19 Resources »      Vaccine Update »      Updated Visitor Policy »      What We're Doing to Keep You Safe »

CLINICAL TRIALS
About Clinical Trials Find a Clinical Trial
CLINICAL TRIALS
About Clinical Trials Find a Clinical Trial

Cetuximab IRDye800 Study as an Optical Imaging Agent to Detect Cancer During Surgical Procedures

Trial ID or NCT#

NCT01987375

Status

not recruiting iconNOT RECRUITING

Purpose

This study is an open label, single institution, Phase 1 dose-escalation study to determine the safety profile of cetuximab-IRDye800 used in subjects with head and neck squamous cell carcinoma (HNSCC) that undergo surgery with curative intent. Participants will be given a dose of an approved head and neck cancer drug (Cetuximab) along with an investigational study drug called Cetuximab-IRDye800. Cetuximab-IRDye800 is a drug that is given prior to surgery that attaches to cancer cells and appears to make them visible to the doctor when he uses a special camera during the operation. The investigators are evaluating whether or not the use of the study drug along with the special camera will better identify the cancer while patients are in the operating room.

Official Title

Phase I, Open-label Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Cetuximab-IRDye800 as an Optical Imaging Agent to Detect Cancer During Surgical Procedures

Eligibility Criteria

Ages Eligible for Study: Older than 19 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
View All Criteria

Investigator(s)

Eben Rosenthal
Eben Rosenthal
Otolaryngologist, Head and neck surgeon
Professor of Otolaryngology - Head & Neck Surgery (OHNS) and of Radiology (Molecular Imaging Program at Stanford)
John B. Sunwoo
John B. Sunwoo
Thyroid and parathyroid surgeon, Cutaneous oncology specialist, Head and neck surgical oncologist, Head and neck surgeon, Endocrine surgeon, Surgical oncologist, Dermato-oncology specialist
Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor, by courtesy, of Dermatology
Vasu Divi, MD
Vasu Divi, MD
Otolaryngologist, Head and neck surgical oncologist, Surgical oncologist, Head and neck surgeon, Facial plastic surgeon
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) at the Stanford University Medical Center
Davud Sirjani, MD
Davud Sirjani, MD
Otolaryngologist, Head and neck surgeon, Head and neck surgical oncologist
Clinical Associate Professor, Otolaryngology (Head and Neck Surgery)
Michael J. Kaplan, MD
Michael J. Kaplan, MD
Head and neck surgical oncologist, Surgical oncologist, Head and neck surgeon, Otolaryngologist
Professor of Otolaryngology - Head and Neck Surgery at the Stanford University Medical Center, Emeritus

Contact us to find out if this trial is right for you.

CONTACT

CCTO
(650) 498-7061

SEND MESSAGE

View on ClinicalTrials.gov