Publications

• CD44+ cells in head and neck squamous cell carcinoma suppress T cell-mediated immunity by selective constitutive and inducible expression of PD-L1.
  Lee, Y., Shin, J. H., Longmire, M., Wang, H., Kohrt, H. E., & Sunwoo, J. B. (2016). CD44+ cells in head and neck squamous cell carcinoma suppress T cell-mediated immunity by selective constitutive and inducible expression of PD-L1. Clinical cancer research : an official journal of the American Association for Cancer Research.
• The Aryl Hydrocarbon Receptor Is Required for The Maintenance of Liver-Resident Natural Killer Cells
  Zhang, L. H., Shin, J. H., Haggadone, M. D., & Sunwoo, J. B. (2016). The Aryl Hydrocarbon Receptor Is Required for The Maintenance of Liver-Resident Natural Killer Cells. The Journal of Experimental Medicine, In Press.
• Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor
  Shin, J. H., Zhang, L., Murillo-Sauca, O., Kim, J., Kohrt, H. Ek., & Sunwoo, J. B. (2013). Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(30), 12391-12396.
• Ameloblastoma: a clinical review and trends in management McClary, A. C., West, R. B., McClary, A. C., Pollack, J. R., Fischbein, N. J., & Sirjani, D. (2016). Ameloblastoma: a clinical review and trends in management. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 273(7), 1649-1661.
  
• Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men Kaveh, A. H., Seminara, N. M., Barnes, M. A., Berger, A. J., Chen, F. W., & Sunwoo, J. B. (2016). Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 38, E754-E760.
  
• Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches. Uppaluri, R., Bell, R. B., & Sunwoo, J. B. (2016). Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches. Oral oncology, 58, 49-51.
  
• Development of prognostic signatures for intermediate-risk papillary thyroid cancer. Brennan, K., Holsinger, C., Dosiou, C., Sunwoo, J. B., Akatsu, H., & Gevaert, O. (2016). Development of prognostic signatures for intermediate-risk papillary thyroid cancer. BMC cancer, 16(1), 736.
  
• Flexible radioluminescence imaging for FDG-guided surgery King, M. T., Jenkins, C. H., Sun, C., Carpenter, C. M., Ma, X., & Xing, L. (2016). Flexible radioluminescence imaging for FDG-guided surgery. Medical Physics, In Press.
  
• ESM1 Mediates NGFR-Induced Invasion and Metastasis in Murine Oral Squamous Cell Carcinoma Chen, C., Shin, J. H., Eggold, J. T., Chung, M. K., Zhang, L. H., & Sunwoo, J. B. (2016). ESM1 Mediates NGFR-Induced Invasion and Metastasis in Murine Oral Squamous Cell Carcinoma. Oncotarget, In Press.
  
• Loss of expression of AZGP1 is associated with worse clinical outcomes in a multi-institutional radical prostatectomy cohort. Brooks, J. D., Wei, W., Pollack, J. R., West, R. B., Shin, J. H., & Fazli, L. (2016). Loss of expression of AZGP1 is associated with worse clinical outcomes in a multi-institutional radical prostatectomy cohort. The Prostate.
  
• Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity Shin, J. H., Haggadone, M. D., & Sunwoo, J. B. (2016). Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity. Biochemistry and Biophysics Reports, 7.
  
• Tumor Ulceration does not Fully Explain Sex Disparities in Melanoma Survival among Adolescents and Young Adults. Keegan, T. H., Swetter, S. M., Tao, L., Sunwoo, J. B., & Clarke, C. A. (2015). Tumor Ulceration does not Fully Explain Sex Disparities in Melanoma Survival among Adolescents and Young Adults. The Journal of investigative dermatology.
  
• A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers Pollom, E. L., Wang, E., Bui, T. T., Ognibene, G., von Eyben, R., & Hara, W. Y. (2015). A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers. ORAL ONCOLOGY, 51(12), 1132-1137.
  
• Immunotherapy for Head and Neck Squamous Cell Carcinoma Schoppy, D. W., & Sunwoo, J. B. (2015). Immunotherapy for Head and Neck Squamous Cell Carcinoma. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 29(6), 1033-?.
  
• beta-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging King, M. T., Carpenter, C. M., Sun, C., Ma, X., Quynh-Thu Le, Q. T., & Xing, L. (2015). beta-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging. JOURNAL OF NUCLEAR MEDICINE, 56(9), 1458-1464.
  
• Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma Farnebo, L., Shahangian, A., Lee, Y., Shin, J. H., Scheeren, F. A., & Sunwoo, J. B. (2015). Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma. ONCOTARGET, 6(12), 9897-9907.
  
• Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1 Le Xuan Truong Nguyen, L. Xt., Lee, Y., Urbani, L., Utz, P. J., Hamburger, A. W., & Mitchell, B. S. (2015). Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1. BLOOD, 125(16), 2519-2529.
  
• CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer. Allen, C. T., Conley, B., Sunwoo, J. B., & Van Waes, C. (2015). CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer. Clinical cancer research , 21(5), 942-943.
  
• CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma Murillo-Sauca, O., Chung, M. K., Shin, J. H., Karamboulas, C., Kwok, S., & Sunwoo, J. B. (2014). CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma. ONCOTARGET, 5(16), 6854-6866.
  
• Targeting CD137 enhances the efficacy of cetuximab. Kohrt, H. E., Colevas, A. D., Houot, R., Weiskopf, K., Goldstein, M. J., & Levy, R. (2014). Targeting CD137 enhances the efficacy of cetuximab. journal of clinical investigation, 124(6), 2668-2682.
  
• Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Protein Induction of Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma Cells Wang, L., Tian, W.-D., Xu, X., Nie, B., Lu, J., & Li, X.-P. (2014). Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Protein Induction of Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma Cells. CANCER, 120(3), 363-372.
  
• Cancer Immunosurveillance and Immunoediting by Natural Killer Cells Gross, E., Sunwoo, J. B., & Bui, J. D. (2013). Cancer Immunosurveillance and Immunoediting by Natural Killer Cells. CANCER JOURNAL, 19(6), 483-489.
  
• Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., & Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. Cancer, 119(7), 1349-1356.
  
• Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells. Liu, J., Zhang, L., Winterroth, L. C., Garcia, M., Weiman, S., & Nadeau, K. C. (2013). Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells. Journal of toxicology, 2013, 967029-?.
  
• Identification of human NK cells that are deficient for signaling adaptor FcR gamma and specialized for antibody-dependent immune functions Hwang, I., Zhang, T., Scott, J. M., Kim, A. R., Lee, T., & Kim, S. (2012). Identification of human NK cells that are deficient for signaling adaptor FcR gamma and specialized for antibody-dependent immune functions. INTERNATIONAL IMMUNOLOGY, 24(12), 793-802.
  
• CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma Janisiewicz, A. M., Shin, J. H., Murillo-Sauca, O., Kwok, S., Quynh-Thu Le, Q. T., & Sunwoo, J. B. (2012). CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(6), 465-470.
  
• The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles Jang, E.-S., Shin, J.-H., Ren, G., Park, M.-J., Cheng, K., & Cheng, Z. (2012). The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles. BIOMATERIALS, 33(22), 5584-5592.
  
• Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab Kohrt, H. E., Houot, R., Weiskopf, K., Goldstein, M., Lund, P., & Levy, R. (2012). Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab. JOURNAL OF CLINICAL ONCOLOGY, 30(15).
  
• The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors Willingham, S. B., Volkmer, J.-P., Gentles, A. J., Sahoo, D., Dalerba, P., & Weissman, I. L. (2012). The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(17), 6662-6667.
  
• Targeted endoscopic salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma Ho, A. S., Kaplan, M. J., Fee, W. E., Yao, M., Sunwoo, J. B., & Hwang, P. H. (2012). Targeted endoscopic salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(2), 166-173.
  
• ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness Judd, N. P., Winkler, A. E., Murillo-Sauca, O., Brotman, J. J., Law, J. H., & Uppaluri, R. (2012). ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness. CANCER RESEARCH, 72(1), 365-374.
  
• A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma Sunwoo, J. B. (2011). A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma. CELL CYCLE, 10(17), 2834-2835.
  
• Distal-less homeobox transcription factors regulate development and maturation of natural killer cells Sunwoo, J. B., Kim, S., Yang, L., Naik, T., Higuchi, D. A., & Yokoyama, W. M. (2008). Distal-less homeobox transcription factors regulate development and maturation of natural killer cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(31), 10877-10882.
  
• Temporal Relationship Between Antitumor Necrosis Factor-alpha Antibody Therapy and Recrudescence of Head and Neck Squamous Cell Carcinoma Engel, S. H., Hullar, T. E., Adkins, D. R., Thorstad, W. L., & Sunwoo, J. B. (2008). Temporal Relationship Between Antitumor Necrosis Factor-alpha Antibody Therapy and Recrudescence of Head and Neck Squamous Cell Carcinoma. LARYNGOSCOPE, 118(3), 450-452.
  
• HLA alleles determine differences in human natural killer cell responsiveness and potency Kim, S., Sunwoo, J. B., Yang, L., Choi, T., Song, Y.-J., & Yokoyama, W. M. (2008). HLA alleles determine differences in human natural killer cell responsiveness and potency. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(8), 3053-3058.
  
• Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia Dunn, G. P., Lewis, J. S., Sunwoo, J. B., & Uppaluri, R. (2008). Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 30(2), 267-272.
  
• Mycotic pseudoaneurysm of the internal maxillary artery - Case report and review of the literature Dunn, G. P., Uppaluri, R., Hessler, J. L., Layland, M. K., Derdeyn, C. P., & Sunwoo, J. B. (2007). Mycotic pseudoaneurysm of the internal maxillary artery - Case report and review of the literature. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 133(4), 402-406.
  
• Arrested natural killer cell development associated with transgene insertion into the Atf2 locus Kim, S., Song, Y. J., Higuchi, D. A., Kang, H. P., Pratt, J. R., & Yokoyama, W. M. (2006). Arrested natural killer cell development associated with transgene insertion into the Atf2 locus. BLOOD, 107(3), 1024-1030.
  
• Inhibition of nuclear factor-kappa B and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma Van Waes, C., Chang, A. A., Lebowitz, P. F., Druzgal, C. H., Chen, Z., & Conley, B. A. (2005). Inhibition of nuclear factor-kappa B and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(5), 1400-1412.
  
• Licensing of natural killer cells by host major histocompatibility complex class I molecules Kim, S., Poursine-Laurent, J., Truscott, S. M., Lybarger, L., Song, Y. J., & Yokoyama, W. M. (2005). Licensing of natural killer cells by host major histocompatibility complex class I molecules. NATURE, 436(7051), 709-713.
  
• Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma Loercher, A., Lee, T. L., Ricker, J. L., Howard, A., Geoghegen, J., & Van Waes, C. (2004). Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. CANCER RESEARCH, 64(18), 6511-6523.
  
• Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappa B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines Bancroft, C. C., Chen, Z., Yeh, J., Sunwoo, J. B., Yeh, N. T., & Van Waes, C. (2002). Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappa B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. INTERNATIONAL JOURNAL OF CANCER, 99(4), 538-548.
  
• Transcript map of the 8p23 putative tumor suppressor region Sun, P. C., Uppaluri, R., Schmidt, A. P., Pashia, M. E., Quant, E. C., & Scholnick, S. B. (2001). Transcript map of the 8p23 putative tumor suppressor region. GENOMICS, 75(1-3), 17-25.
  
• IL (interleukin)-1 alpha promotes nuclear factor-kappa B and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas Wolf, J. S., Chen, Z., Dong, G., Sunwoo, J. B., Bancroft, C. C., & Van Waes, C. (2001). IL (interleukin)-1 alpha promotes nuclear factor-kappa B and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. CLINICAL CANCER RESEARCH, 7(6), 1812-1820.
  
• Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma Sunwoo, J. B., Chen, Z., Dong, G., Yeh, N., Bancroft, C. G., & Van Waes, C. (2001). Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. CLINICAL CANCER RESEARCH, 7(5), 1419-1428.
  
• Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways Bancroft, C. C., Chen, Z., Dong, G., Sunwoo, J. B., Yeh, N., & Van Waes, C. (2001). Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways. CLINICAL CANCER RESEARCH, 7(2), 435-442.
  
• Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer Sunwoo, J. B., Herscher, L. L., Kroog, G. S., Thomas, G. R., Ondrey, F. G., & Van Waes, C. (2001). Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY, 19(3), 800-811.
  
• Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene Sun, P. C., Schmidt, A. P., Pashia, M. E., Sunwoo, J. B., & Scholnick, S. B. (1999). Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene. GENOMICS, 62(2), 184-188.
  
• Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma Gupta, V. K., Schmidt, A. P., Pashia, M. E., Sunwoo, J. B., & Scholnick, S. B. (1999). Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma. INTERNATIONAL JOURNAL OF CANCER, 84(5), 453-457.
  
• Constitutive activation of transcription factors NF-kappa B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines Ondrey, F. G., Dong, G., Sunwoo, J., Chen, Z., Wolf, J. S., & Van Waes, C. (1999). Constitutive activation of transcription factors NF-kappa B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines. MOLECULAR CARCINOGENESIS, 26(2), 119-129.
  
• Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p Sunwoo, J. B., Sun, P. C., Gupta, V. K., Schmidt, A. P., El-Mofty, S., & Scholnick, S. B. (1999). Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p. ONCOGENE, 18(16), 2651-2655.
  
• Clinical correlations with allelotype in supraglottic squamous cancer Scholnick, S. B., El-Mofty, S. K., Shaw, M. E., Sunwoo, J. B., Haughey, B. H., & Zequeira, M. R. (1998). Clinical correlations with allelotype in supraglottic squamous cancer. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 118(3), 363-370.
  
• Chromosome 8 allelic loss and the outcome of patients with squamous cell carcinoma of the supraglottic larynx Scholnick, S. B., Haughey, B. H., Sunwoo, J. B., ELMOFTY, S. K., Baty, J. D., & Zequeira, M. R. (1996). Chromosome 8 allelic loss and the outcome of patients with squamous cell carcinoma of the supraglottic larynx. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 88(22), 1676-1682.
  
• Evidence for multiple tumor suppressor genes on chromosome arm 8p in supraglottic laryngeal cancer Sunwoo, J. B., Holt, M. S., Radford, D. M., Deeker, C., & Scholnick, S. B. (1996). Evidence for multiple tumor suppressor genes on chromosome arm 8p in supraglottic laryngeal cancer. GENES CHROMOSOMES & CANCER, 16(3), 164-169.
  
• CELL-CYCLE OSCILLATION OF PHOSPHATASE INHIBITOR-2 IN RAT FIBROBLASTS COINCIDENT WITH P34CDC2 RESTRICTION Brautigan, D. L., Sunwoo, J., Labbe, J. C., Fernandez, A., & Lamb, N. Jc. (1990). CELL-CYCLE OSCILLATION OF PHOSPHATASE INHIBITOR-2 IN RAT FIBROBLASTS COINCIDENT WITH P34CDC2 RESTRICTION. NATURE, 344(6261), 74-78.