Publications

• Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p
  Sunwoo, J. B., Sun, P. C., Gupta, V. K., Schmidt, A. P., El-Mofty, S., & Scholnick, S. B. (1999). Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p. ONCOGENE, 18(16), 2651–2655.
• Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma
  Gupta, V. K., Schmidt, A. P., Pashia, M. E., Sunwoo, J. B., & Scholnick, S. B. (1999). Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma. INTERNATIONAL JOURNAL OF CANCER, 84(5), 453–457.
• Constitutive activation of transcription factors NF-kappa B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines
  Ondrey, F. G., Dong, G., Sunwoo, J., Chen, Z., Wolf, J. S., Crowl-Bancroft, C. V., … Van Waes, C. (1999). Constitutive activation of transcription factors NF-kappa B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines. MOLECULAR CARCINOGENESIS, 26(2), 119–129.
• Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene Sun, P. C., Schmidt, A. P., Pashia, M. E., Sunwoo, J. B., & Scholnick, S. B. (1999). Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene. GENOMICS, 62(2), 184–188.
  
• Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer Sunwoo, J. B., Herscher, L. L., Kroog, G. S., Thomas, G. R., Ondrey, F. G., Duffey, D. C., … Van Waes, C. (2001). Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY, 19(3), 800–811.
  
• Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways Bancroft, C. C., Chen, Z., Dong, G., Sunwoo, J. B., Yeh, N., PARK, C., & Van Waes, C. (2001). Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways. CLINICAL CANCER RESEARCH, 7(2), 435–442.
  
• Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma Sunwoo, J. B., Chen, Z., Dong, G., Yeh, N., Bancroft, C. G., Sausville, E., … Van Waes, C. (2001). Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. CLINICAL CANCER RESEARCH, 7(5), 1419–1428.
  
• IL (interleukin)-1 alpha promotes nuclear factor-kappa B and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas Wolf, J. S., Chen, Z., Dong, G., Sunwoo, J. B., Bancroft, C. C., Capo, D. E., … Van Waes, C. (2001). IL (interleukin)-1 alpha promotes nuclear factor-kappa B and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. CLINICAL CANCER RESEARCH, 7(6), 1812–1820.
  
• Transcript map of the 8p23 putative tumor suppressor region Sun, P. C., Uppaluri, R., Schmidt, A. P., Pashia, M. E., Quant, E. C., Sunwoo, J. B., … Scholnick, S. B. (2001). Transcript map of the 8p23 putative tumor suppressor region. GENOMICS, 75(1-3), 17–25.
  
• Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappa B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines Bancroft, C. C., Chen, Z., Yeh, J., Sunwoo, J. B., Yeh, N. T., Jackson, S., … Van Waes, C. (2002). Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappa B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. INTERNATIONAL JOURNAL OF CANCER, 99(4), 538–548.
  
• Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma Loercher, A., Lee, T. L., Ricker, J. L., Howard, A., Geoghegen, J., Chen, Z., … Van Waes, C. (2004). Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. CANCER RESEARCH, 64(18), 6511–6523.
  
• Inhibition of nuclear factor-kappa B and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma Van Waes, C., Chang, A. A., Lebowitz, P. F., Druzgal, C. H., Chen, Z., Elsayed, Y. A., … Conley, B. A. (2005). Inhibition of nuclear factor-kappa B and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(5), 1400–1412.
  
• Licensing of natural killer cells by host major histocompatibility complex class I molecules Kim, S., Poursine-Laurent, J., Truscott, S. M., Lybarger, L., Song, Y. J., Yang, L. P., … Yokoyama, W. M. (2005). Licensing of natural killer cells by host major histocompatibility complex class I molecules. NATURE, 436(7051), 709–713.
  
• Arrested natural killer cell development associated with transgene insertion into the Atf2 locus Kim, S., Song, Y. J., Higuchi, D. A., Kang, H. P., Pratt, J. R., Yang, L. P., … Yokoyama, W. M. (2006). Arrested natural killer cell development associated with transgene insertion into the Atf2 locus. BLOOD, 107(3), 1024–1030.
  
• Mycotic pseudoaneurysm of the internal maxillary artery - Case report and review of the literature Dunn, G. P., Uppaluri, R., Hessler, J. L., Layland, M. K., Derdeyn, C. P., & Sunwoo, J. B. (2007). Mycotic pseudoaneurysm of the internal maxillary artery - Case report and review of the literature. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 133(4), 402–406.
  
• Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia Dunn, G. P., Lewis, J. S., Sunwoo, J. B., & Uppaluri, R. (2008). Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 30(2), 267–272.
  
• Temporal Relationship Between Antitumor Necrosis Factor-alpha Antibody Therapy and Recrudescence of Head and Neck Squamous Cell Carcinoma Engel, S. H., Hullar, T. E., Adkins, D. R., Thorstad, W. L., & Sunwoo, J. B. (2008). Temporal Relationship Between Antitumor Necrosis Factor-alpha Antibody Therapy and Recrudescence of Head and Neck Squamous Cell Carcinoma. LARYNGOSCOPE, 118(3), 450–452.
  
• HLA alleles determine differences in human natural killer cell responsiveness and potency Kim, S., Sunwoo, J. B., Yang, L., Choi, T., Song, Y.-J., French, A. R., … Yokoyama, W. M. (2008). HLA alleles determine differences in human natural killer cell responsiveness and potency. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(8), 3053–3058.
  
• Distal-less homeobox transcription factors regulate development and maturation of natural killer cells Sunwoo, J. B., Kim, S., Yang, L., Naik, T., Higuchi, D. A., Rubenstein, J. L., & Yokoyama, W. M. (2008). Distal-less homeobox transcription factors regulate development and maturation of natural killer cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(31), 10877–10882.
  
• A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma Sunwoo, J. B. (2011). A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma. CELL CYCLE, 10(17), 2834–35.
  
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• The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors Willingham, S. B., Volkmer, J.-P., Gentles, A. J., Sahoo, D., Dalerba, P., Mitra, S. S., … Weissman, I. L. (2012). The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(17), 6662–67.
  
• The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles Jang, E.-S., Shin, J.-H., Ren, G., Park, M.-J., Cheng, K., Chen, X., … Cheng, Z. (2012). The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles. BIOMATERIALS, 33(22), 5584–92.
  
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• Identification of human NK cells that are deficient for signaling adaptor FcR gamma and specialized for antibody-dependent immune functions Hwang, I., Zhang, T., Scott, J. M., Kim, A. R., Lee, T., Kakarla, T., … Kim, S. (2012). Identification of human NK cells that are deficient for signaling adaptor FcR gamma and specialized for antibody-dependent immune functions. INTERNATIONAL IMMUNOLOGY, 24(12), 793–802.
  
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• Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells. Liu, J., Zhang, L., Winterroth, L. C., Garcia, M., Weiman, S., Wong, J. W., … Nadeau, K. C. (2013). Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells. Journal of Toxicology, 2013, 967029-?
  
• CELL-CYCLE OSCILLATION OF PHOSPHATASE INHIBITOR-2 IN RAT FIBROBLASTS COINCIDENT WITH P34CDC2 RESTRICTION Brautigan, D. L., Sunwoo, J., Labbe, J. C., Fernandez, A., & Lamb, N. J. C. (1990). CELL-CYCLE OSCILLATION OF PHOSPHATASE INHIBITOR-2 IN RAT FIBROBLASTS COINCIDENT WITH P34CDC2 RESTRICTION. NATURE, 344(6261), 74–78.
  
• Evidence for multiple tumor suppressor genes on chromosome arm 8p in supraglottic laryngeal cancer Sunwoo, J. B., Holt, M. S., Radford, D. M., Deeker, C., & Scholnick, S. B. (1996). Evidence for multiple tumor suppressor genes on chromosome arm 8p in supraglottic laryngeal cancer. GENES CHROMOSOMES & CANCER, 16(3), 164–169.
  
• Chromosome 8 allelic loss and the outcome of patients with squamous cell carcinoma of the supraglottic larynx Scholnick, S. B., Haughey, B. H., Sunwoo, J. B., ELMOFTY, S. K., Baty, J. D., Piccirillo, J. F., & Zequeira, M. R. (1996). Chromosome 8 allelic loss and the outcome of patients with squamous cell carcinoma of the supraglottic larynx. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 88(22), 1676–1682.
  
• Clinical correlations with allelotype in supraglottic squamous cancer Scholnick, S. B., El-Mofty, S. K., Shaw, M. E., Sunwoo, J. B., Haughey, B. H., Sun, P. C., … Zequeira, M. R. (1998). Clinical correlations with allelotype in supraglottic squamous cancer. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 118(3), 363–370.
  
• Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab Kohrt, H. E., Houot, R., Weiskopf, K., Goldstein, M., Lund, P., Scheeren, F., … Levy, R. (2012). Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab. JOURNAL OF CLINICAL ONCOLOGY, 30(15).
  
• Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor Shin, J. H., Zhang, L., Murillo-Sauca, O., Kim, J., Kohrt, H. E. K., Bui, J. D., & Sunwoo, J. B. (2013). Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(30), 12391–96.
  
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• Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Protein Induction of Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma Cells Wang, L., Tian, W.-D., Xu, X., Nie, B., Lu, J., Liu, X., … Li, X.-P. (2014). Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Protein Induction of Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma Cells. CANCER, 120(3), 363–72.
  
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• CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer. Allen, C. T., Conley, B., Sunwoo, J. B., & Van Waes, C. (2015). CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer. Clinical Cancer Research , 21(5), 942–43.
  
• Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men Kaveh, A. H., Seminara, N. M., Barnes, M. A., Berger, A. J., Chen, F. W., Yao, M., … Sunwoo, J. B. (2016). Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 38, E754–E760.
  
• Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma. Farnebo, L., Shahangian, A., Lee, Y., Shin, J. H., Scheeren, F. A., & Sunwoo, J. B. (2015). Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma. Oncotarget, 6(12), 9897–9907.
  
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• Tumor Ulceration Does Not Fully Explain Sex Disparities in Melanoma Survival among Adolescents and Young Adults. Keegan, T. H. M., Swetter, S. M., Tao, L., Sunwoo, J. B., & Clarke, C. A. (2015). Tumor Ulceration Does Not Fully Explain Sex Disparities in Melanoma Survival among Adolescents and Young Adults. Journal of Investigative Dermatology, 135(12), 3195–97.
  
• ß-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging. King, M. T., Carpenter, C. M., Sun, C., Ma, X., Le, Q.-T., Sunwoo, J. B., … Xing, L. (2015). ß-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 56(9), 1458–64.
  
• A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers. Pollom, E. L., Wang, E., Bui, T. T., Ognibene, G., von Eyben, R., Divi, V., … Hara, W. Y. (2015). A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers. Oral Oncology, 51(12), 1132–37.
  
• Immunotherapy for Head and Neck Squamous Cell Carcinoma. Schoppy, D. W., & Sunwoo, J. B. (2015). Immunotherapy for Head and Neck Squamous Cell Carcinoma. Hematology/Oncology Clinics of North America, 29(6), 1033–43.
  
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• Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort. Brooks, J. D., Wei, W., Pollack, J. R., West, R. B., Shin, J. H., Sunwoo, J. B., … Fazli, L. (2016). Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort. Prostate, 76(15), 1409–19.
  
• Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches. Uppaluri, R., Bell, R. B., & Sunwoo, J. B. (2016). Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches. Oral Oncology, 58, 49–51.
  
• Development of prognostic signatures for intermediate-risk papillary thyroid cancer. Brennan, K., Holsinger, C., Dosiou, C., Sunwoo, J. B., Akatsu, H., Haile, R., & Gevaert, O. (2016). Development of prognostic signatures for intermediate-risk papillary thyroid cancer. BMC Cancer, 16(1), 736-?
  
• Flexible radioluminescence imaging for FDG-guided surgery King, M. T., Jenkins, C. H., Sun, C., Carpenter, C. M., Ma, X., Cheng, K., … Xing, L. (2016). Flexible radioluminescence imaging for FDG-guided surgery. MEDICAL PHYSICS, 43(10).
  
• Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity. Shin, J. H., Haggadone, M. D., & Sunwoo, J. B. (2016). Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity. Biochemistry and Biophysics Reports, 7, 353–60.
  
• The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells. Zhang, L. H., Shin, J. H., Haggadone, M. D., & Sunwoo, J. B. (2016). The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells. Journal of Experimental Medicine, 213(11), 2249–57.
  
• Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor. Kim, J., Ho Shin, J., Chen, C.-H., Cruz, L., Farnebo, L., Yang, J., … Sunwoo, J. B. (2017). Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor. Oncotarget.
  
• Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype. Brennan, K., Koenig, J. L., Gentles, A. J., Sunwoo, J. B., & Gevaert, O. (2017). Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype. EBioMedicine, 17, 223–36.
  
• Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes. Amoils, M., Lee, C. S., Sunwoo, J., Aasi, S. Z., Hara, W., Kim, J., … Divi, V. (2017). Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes. Head & Neck.
  
• ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma Chen, C., Shin, J. H., Eggold, J. T., Chung, M. K., Zhang, L. H., Lee, J., & Sunwoo, J. B. (2016). ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma. ONCOTARGET, 7(43), 70738–49.
  
• Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy MAKKOUK, A., Sundaram, V., Chester, C., Chang, S., Colevas, A. D., Sunwoo, J. B., … Kohrt, H. E. (2017). Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy. ANNALS OF ONCOLOGY, 28(2), 415–20.
  
• NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma. Brennan, K., Shin, J. H., Tay, J. K., Prunello, M., Gentles, A. J., Sunwoo, J. B., & Gevaert, O. (2017). NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma. Scientific Reports, 7(1), 17064.
  
• CD271 Confers an Invasive and Metastatic Phenotype of Head and Neck Squamous Cell Carcinoma Through the Upregulation of Slug. Chung, M. K., Jung, Y. H., Lee, J. K., Cho, S. Y., Murillo-Sauca, O. J., Uppaluri, R., … Sunwoo, J. B. (2017). CD271 Confers an Invasive and Metastatic Phenotype of Head and Neck Squamous Cell Carcinoma Through the Upregulation of Slug. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research.
  
• The aryl hydrocarbon receptor modulates the function of human CD56bright NK cells. Moreno-Nieves, U. Y., Mundy, D. C., Shin, J. H., Tam, K., & Sunwoo, J. B. (2018). The aryl hydrocarbon receptor modulates the function of human CD56bright NK cells. European Journal of Immunology.
  
• Assessing the Impact of Targeting CEACAM1 in Head and Neck Squamous Cell Carcinoma. Tam, K., Schoppy, D. W., Shin, J. H., Tay, J. K., Moreno-Nieves, U., Mundy, D. C., & Sunwoo, J. B. (2018). Assessing the Impact of Targeting CEACAM1 in Head and Neck Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599818756627.
  
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• PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma. Amoils, M., Kim, J., Lee, C., Sunwoo, J. B., Colevas, A. D., Aasi, S. Z., … Divi, A. V. (2018). PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599818788057.
  
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