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Biography
Dr. Sunwoo was born and raised in St. Louis, Missouri. He received his undergraduate degree from Brown University in Providence, Rhode Island and his medical degree from Washington University in St. Louis, Missouri. He completed his training in Otolaryngology – Head and Neck Surgery at Washington University. Dr. Sunwoo has been at Stanford University since 2008, and his clinical focus is on the surgical management of head and neck cancer, specifically focusing on melanoma and neoplasms of the thyroid and parathyroid glands. He is a member of the Pigmented Lesions and Melanoma Clinic and the Melanoma Working Group at Stanford. He is also the co-founder of the Stanford Thyroid and Parathyroid Tumor Board.
In addition to his clinical work, Dr. Sunwoo is the Director of Head and Neck Cancer Research at Stanford University and the principal investigator of an NIH-funded laboratory in the Stanford Cancer Institute. His research is focused on three primary areas: (1) the immune response to cancer, particularly a tumorigenic population of cells within malignancies called cancer stem cells; (2) the biology and developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells; and (3) intra-tumor and inter-tumor heterogeneity in head and neck cancer.
In addition to his clinical work, Dr. Sunwoo is the Director of Head and Neck Cancer Research at Stanford University and the principal investigator of an NIH-funded laboratory in the Stanford Cancer Institute. His research is focused on three primary areas: (1) the immune response to cancer, particularly a tumorigenic population of cells within malignancies called cancer stem cells; (2) the biology and developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells; and (3) intra-tumor and inter-tumor heterogeneity in head and neck cancer.
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Professional Summary
Education & Certifications
- Residency: Washington University School Of Medicine Registrar (2003) MO
- Medical Education: Washington University School Of Medicine Registrar (1993) MO
- Postdoc Research Fellowship, Washington University, Immunology (2008)
- Board Certification: American Board of Otolaryngology, Otolaryngology (2004)
- Fellowship: National Institutes of Health (2000) MD
- M.D., Washington University, Medicine (1993)
- Sc.B., Brown University, Biochemistry (1989)
Awards & Memberships
- Alpha Omega Alpha, Washington University (2003)
- Best Doctors in America, Best Doctors, Inc. (2009-present)
- Chief Resident Teaching Award, Washington University (2003)
- Faculty Teacher of the Year, Dept. of Otolaryngology, Stanford University (2012)
- K08 Award, National Institutes of Health (2004)
- Louis and Dorothy Kovitz Prize in Surgery, Washington University (1993)
- R35 Outstanding Investigator Award, NIH (2020)
- Resident Research Award, Washington University (1997, 1999, 2000)
- Sigma Xi, Brown University (1989)
- Top Doctors, Castle Connolly (2013 - present)
- Young Investigator Award, American Head and Neck Society (2000)
Administrative Appointments
- Associate Dean for Academic Affairs (UTL), Stanford University School of Medicine (2019 - Present)
- Director of Head and Neck Cancer Research, Stanford University School of Medicine, Dept. of Otolaryngology (2013 - Present)
- Leader, Head and Neck Cancer Service Line (CCP), Stanford Cancer Institute (2017 - Present)
Publications
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Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p
Sunwoo, J. B., Sun, P. C., Gupta, V. K., Schmidt, A. P., El-Mofty, S., & Scholnick, S. B. (1999). Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p. ONCOGENE, 18(16), 2651–2655. -
Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma
Gupta, V. K., Schmidt, A. P., Pashia, M. E., Sunwoo, J. B., & Scholnick, S. B. (1999). Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma. INTERNATIONAL JOURNAL OF CANCER, 84(5), 453–457. -
Constitutive activation of transcription factors NF-kappa B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines
Ondrey, F. G., Dong, G., Sunwoo, J., Chen, Z., Wolf, J. S., Crowl-Bancroft, C. V., … Van Waes, C. (1999). Constitutive activation of transcription factors NF-kappa B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines. MOLECULAR CARCINOGENESIS, 26(2), 119–129. -
Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene
Sun, P. C., Schmidt, A. P., Pashia, M. E., Sunwoo, J. B., & Scholnick, S. B. (1999). Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene. GENOMICS, 62(2), 184–188. -
Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer
Sunwoo, J. B., Herscher, L. L., Kroog, G. S., Thomas, G. R., Ondrey, F. G., Duffey, D. C., … Van Waes, C. (2001). Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY, 19(3), 800–811. -
Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways
Bancroft, C. C., Chen, Z., Dong, G., Sunwoo, J. B., Yeh, N., PARK, C., & Van Waes, C. (2001). Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways. CLINICAL CANCER RESEARCH, 7(2), 435–442. -
Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
Sunwoo, J. B., Chen, Z., Dong, G., Yeh, N., Bancroft, C. G., Sausville, E., … Van Waes, C. (2001). Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. CLINICAL CANCER RESEARCH, 7(5), 1419–1428. -
IL (interleukin)-1 alpha promotes nuclear factor-kappa B and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas
Wolf, J. S., Chen, Z., Dong, G., Sunwoo, J. B., Bancroft, C. C., Capo, D. E., … Van Waes, C. (2001). IL (interleukin)-1 alpha promotes nuclear factor-kappa B and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. CLINICAL CANCER RESEARCH, 7(6), 1812–1820. -
Transcript map of the 8p23 putative tumor suppressor region
Sun, P. C., Uppaluri, R., Schmidt, A. P., Pashia, M. E., Quant, E. C., Sunwoo, J. B., … Scholnick, S. B. (2001). Transcript map of the 8p23 putative tumor suppressor region. GENOMICS, 75(1-3), 17–25. -
Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappa B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines
Bancroft, C. C., Chen, Z., Yeh, J., Sunwoo, J. B., Yeh, N. T., Jackson, S., … Van Waes, C. (2002). Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappa B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. INTERNATIONAL JOURNAL OF CANCER, 99(4), 538–548. -
Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma
Loercher, A., Lee, T. L., Ricker, J. L., Howard, A., Geoghegen, J., Chen, Z., … Van Waes, C. (2004). Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. CANCER RESEARCH, 64(18), 6511–6523. -
Inhibition of nuclear factor-kappa B and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma
Van Waes, C., Chang, A. A., Lebowitz, P. F., Druzgal, C. H., Chen, Z., Elsayed, Y. A., … Conley, B. A. (2005). Inhibition of nuclear factor-kappa B and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(5), 1400–1412. -
Licensing of natural killer cells by host major histocompatibility complex class I molecules
Kim, S., Poursine-Laurent, J., Truscott, S. M., Lybarger, L., Song, Y. J., Yang, L. P., … Yokoyama, W. M. (2005). Licensing of natural killer cells by host major histocompatibility complex class I molecules. NATURE, 436(7051), 709–713. -
Arrested natural killer cell development associated with transgene insertion into the Atf2 locus
Kim, S., Song, Y. J., Higuchi, D. A., Kang, H. P., Pratt, J. R., Yang, L. P., … Yokoyama, W. M. (2006). Arrested natural killer cell development associated with transgene insertion into the Atf2 locus. BLOOD, 107(3), 1024–1030. -
Mycotic pseudoaneurysm of the internal maxillary artery - Case report and review of the literature
Dunn, G. P., Uppaluri, R., Hessler, J. L., Layland, M. K., Derdeyn, C. P., & Sunwoo, J. B. (2007). Mycotic pseudoaneurysm of the internal maxillary artery - Case report and review of the literature. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 133(4), 402–406. -
Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia
Dunn, G. P., Lewis, J. S., Sunwoo, J. B., & Uppaluri, R. (2008). Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 30(2), 267–272. -
Temporal Relationship Between Antitumor Necrosis Factor-alpha Antibody Therapy and Recrudescence of Head and Neck Squamous Cell Carcinoma
Engel, S. H., Hullar, T. E., Adkins, D. R., Thorstad, W. L., & Sunwoo, J. B. (2008). Temporal Relationship Between Antitumor Necrosis Factor-alpha Antibody Therapy and Recrudescence of Head and Neck Squamous Cell Carcinoma. LARYNGOSCOPE, 118(3), 450–452. -
HLA alleles determine differences in human natural killer cell responsiveness and potency
Kim, S., Sunwoo, J. B., Yang, L., Choi, T., Song, Y.-J., French, A. R., … Yokoyama, W. M. (2008). HLA alleles determine differences in human natural killer cell responsiveness and potency. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(8), 3053–3058. -
Distal-less homeobox transcription factors regulate development and maturation of natural killer cells
Sunwoo, J. B., Kim, S., Yang, L., Naik, T., Higuchi, D. A., Rubenstein, J. L., & Yokoyama, W. M. (2008). Distal-less homeobox transcription factors regulate development and maturation of natural killer cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(31), 10877–10882. -
A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma
Sunwoo, J. B. (2011). A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma. CELL CYCLE, 10(17), 2834–35. -
ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness
Judd, N. P., Winkler, A. E., Murillo-Sauca, O., Brotman, J. J., Law, J. H., Lewis, J. S., … Uppaluri, R. (2012). ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness. CANCER RESEARCH, 72(1), 365–74. -
Targeted endoscopic salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma
Ho, A. S., Kaplan, M. J., Fee, W. E., Yao, M., Sunwoo, J. B., & Hwang, P. H. (2012). Targeted endoscopic salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(2), 166–73. -
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
Willingham, S. B., Volkmer, J.-P., Gentles, A. J., Sahoo, D., Dalerba, P., Mitra, S. S., … Weissman, I. L. (2012). The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(17), 6662–67. -
The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles
Jang, E.-S., Shin, J.-H., Ren, G., Park, M.-J., Cheng, K., Chen, X., … Cheng, Z. (2012). The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles. BIOMATERIALS, 33(22), 5584–92. -
CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma
Janisiewicz, A. M., Shin, J. H., Murillo-Sauca, O., Kwok, S., Quynh-Thu Le, Q. T., Kong, C., … Sunwoo, J. B. (2012). CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(6), 465–70. -
Identification of human NK cells that are deficient for signaling adaptor FcR gamma and specialized for antibody-dependent immune functions
Hwang, I., Zhang, T., Scott, J. M., Kim, A. R., Lee, T., Kakarla, T., … Kim, S. (2012). Identification of human NK cells that are deficient for signaling adaptor FcR gamma and specialized for antibody-dependent immune functions. INTERNATIONAL IMMUNOLOGY, 24(12), 793–802. -
Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence.
Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., Colevas, A. D., … Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. Cancer, 119(7), 1349–56. -
Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells.
Liu, J., Zhang, L., Winterroth, L. C., Garcia, M., Weiman, S., Wong, J. W., … Nadeau, K. C. (2013). Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells. Journal of Toxicology, 2013, 967029-? -
CELL-CYCLE OSCILLATION OF PHOSPHATASE INHIBITOR-2 IN RAT FIBROBLASTS COINCIDENT WITH P34CDC2 RESTRICTION
Brautigan, D. L., Sunwoo, J., Labbe, J. C., Fernandez, A., & Lamb, N. J. C. (1990). CELL-CYCLE OSCILLATION OF PHOSPHATASE INHIBITOR-2 IN RAT FIBROBLASTS COINCIDENT WITH P34CDC2 RESTRICTION. NATURE, 344(6261), 74–78. -
Evidence for multiple tumor suppressor genes on chromosome arm 8p in supraglottic laryngeal cancer
Sunwoo, J. B., Holt, M. S., Radford, D. M., Deeker, C., & Scholnick, S. B. (1996). Evidence for multiple tumor suppressor genes on chromosome arm 8p in supraglottic laryngeal cancer. GENES CHROMOSOMES & CANCER, 16(3), 164–169. -
Chromosome 8 allelic loss and the outcome of patients with squamous cell carcinoma of the supraglottic larynx
Scholnick, S. B., Haughey, B. H., Sunwoo, J. B., ELMOFTY, S. K., Baty, J. D., Piccirillo, J. F., & Zequeira, M. R. (1996). Chromosome 8 allelic loss and the outcome of patients with squamous cell carcinoma of the supraglottic larynx. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 88(22), 1676–1682. -
Clinical correlations with allelotype in supraglottic squamous cancer
Scholnick, S. B., El-Mofty, S. K., Shaw, M. E., Sunwoo, J. B., Haughey, B. H., Sun, P. C., … Zequeira, M. R. (1998). Clinical correlations with allelotype in supraglottic squamous cancer. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 118(3), 363–370. -
Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab
Kohrt, H. E., Houot, R., Weiskopf, K., Goldstein, M., Lund, P., Scheeren, F., … Levy, R. (2012). Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab. JOURNAL OF CLINICAL ONCOLOGY, 30(15). -
Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor
Shin, J. H., Zhang, L., Murillo-Sauca, O., Kim, J., Kohrt, H. E. K., Bui, J. D., & Sunwoo, J. B. (2013). Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(30), 12391–96. -
Cancer immunosurveillance and immunoediting by natural killer cells.
Gross, E., Sunwoo, J. B., & Bui, J. D. (2013). Cancer immunosurveillance and immunoediting by natural killer cells. Cancer Journal , 19(6), 483–89. -
Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Protein Induction of Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma Cells
Wang, L., Tian, W.-D., Xu, X., Nie, B., Lu, J., Liu, X., … Li, X.-P. (2014). Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Protein Induction of Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma Cells. CANCER, 120(3), 363–72. -
Targeting CD137 enhances the efficacy of cetuximab.
Kohrt, H. E., Colevas, A. D., Houot, R., Weiskopf, K., Goldstein, M. J., Lund, P., … Levy, R. (2014). Targeting CD137 enhances the efficacy of cetuximab. Journal of Clinical Investigation, 124(6), 2668–82. -
CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.
Murillo-Sauca, O., Chung, M. K., Shin, J. H., Karamboulas, C., Kwok, S., Jung, Y. H., … Sunwoo, J. B. (2014). CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma. Oncotarget, 5(16), 6854–66. -
Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1.
Nguyen, L. X. T., Lee, Y., Urbani, L., Utz, P. J., Hamburger, A. W., Sunwoo, J. B., & Mitchell, B. S. (2015). Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1. Blood, 125(16), 2519–29. -
CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer.
Allen, C. T., Conley, B., Sunwoo, J. B., & Van Waes, C. (2015). CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer. Clinical Cancer Research , 21(5), 942–43. -
Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men
Kaveh, A. H., Seminara, N. M., Barnes, M. A., Berger, A. J., Chen, F. W., Yao, M., … Sunwoo, J. B. (2016). Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 38, E754–E760. -
Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma.
Farnebo, L., Shahangian, A., Lee, Y., Shin, J. H., Scheeren, F. A., & Sunwoo, J. B. (2015). Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma. Oncotarget, 6(12), 9897–9907. -
Ameloblastoma: a clinical review and trends in management
McClary, A. C., West, R. B., McClary, A. C., Pollack, J. R., Fischbein, N. J., Holsinger, C. F., … Sirjani, D. (2016). Ameloblastoma: a clinical review and trends in management. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 273(7), 1649–61. -
Tumor Ulceration Does Not Fully Explain Sex Disparities in Melanoma Survival among Adolescents and Young Adults.
Keegan, T. H. M., Swetter, S. M., Tao, L., Sunwoo, J. B., & Clarke, C. A. (2015). Tumor Ulceration Does Not Fully Explain Sex Disparities in Melanoma Survival among Adolescents and Young Adults. Journal of Investigative Dermatology, 135(12), 3195–97. -
ß-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging.
King, M. T., Carpenter, C. M., Sun, C., Ma, X., Le, Q.-T., Sunwoo, J. B., … Xing, L. (2015). ß-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 56(9), 1458–64. -
A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers.
Pollom, E. L., Wang, E., Bui, T. T., Ognibene, G., von Eyben, R., Divi, V., … Hara, W. Y. (2015). A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers. Oral Oncology, 51(12), 1132–37. -
Immunotherapy for Head and Neck Squamous Cell Carcinoma.
Schoppy, D. W., & Sunwoo, J. B. (2015). Immunotherapy for Head and Neck Squamous Cell Carcinoma. Hematology/Oncology Clinics of North America, 29(6), 1033–43. -
CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell-Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1.
Lee, Y., Shin, J. H., Longmire, M., Wang, H., Kohrt, H. E., Chang, H. Y., & Sunwoo, J. B. (2016). CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell-Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1. Clinical Cancer Research , 22(14), 3571–81. -
Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort.
Brooks, J. D., Wei, W., Pollack, J. R., West, R. B., Shin, J. H., Sunwoo, J. B., … Fazli, L. (2016). Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort. Prostate, 76(15), 1409–19. -
Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches.
Uppaluri, R., Bell, R. B., & Sunwoo, J. B. (2016). Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches. Oral Oncology, 58, 49–51. -
Development of prognostic signatures for intermediate-risk papillary thyroid cancer.
Brennan, K., Holsinger, C., Dosiou, C., Sunwoo, J. B., Akatsu, H., Haile, R., & Gevaert, O. (2016). Development of prognostic signatures for intermediate-risk papillary thyroid cancer. BMC Cancer, 16(1), 736-? -
Flexible radioluminescence imaging for FDG-guided surgery
King, M. T., Jenkins, C. H., Sun, C., Carpenter, C. M., Ma, X., Cheng, K., … Xing, L. (2016). Flexible radioluminescence imaging for FDG-guided surgery. MEDICAL PHYSICS, 43(10). -
Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity.
Shin, J. H., Haggadone, M. D., & Sunwoo, J. B. (2016). Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity. Biochemistry and Biophysics Reports, 7, 353–60. -
The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells.
Zhang, L. H., Shin, J. H., Haggadone, M. D., & Sunwoo, J. B. (2016). The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells. Journal of Experimental Medicine, 213(11), 2249–57. -
Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor.
Kim, J., Ho Shin, J., Chen, C.-H., Cruz, L., Farnebo, L., Yang, J., … Sunwoo, J. B. (2017). Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor. Oncotarget. -
Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype.
Brennan, K., Koenig, J. L., Gentles, A. J., Sunwoo, J. B., & Gevaert, O. (2017). Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype. EBioMedicine, 17, 223–36. -
Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes.
Amoils, M., Lee, C. S., Sunwoo, J., Aasi, S. Z., Hara, W., Kim, J., … Divi, V. (2017). Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes. Head & Neck. -
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma
Chen, C., Shin, J. H., Eggold, J. T., Chung, M. K., Zhang, L. H., Lee, J., & Sunwoo, J. B. (2016). ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma. ONCOTARGET, 7(43), 70738–49. -
Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy
MAKKOUK, A., Sundaram, V., Chester, C., Chang, S., Colevas, A. D., Sunwoo, J. B., … Kohrt, H. E. (2017). Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy. ANNALS OF ONCOLOGY, 28(2), 415–20. -
NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma.
Brennan, K., Shin, J. H., Tay, J. K., Prunello, M., Gentles, A. J., Sunwoo, J. B., & Gevaert, O. (2017). NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma. Scientific Reports, 7(1), 17064. -
CD271 Confers an Invasive and Metastatic Phenotype of Head and Neck Squamous Cell Carcinoma Through the Upregulation of Slug.
Chung, M. K., Jung, Y. H., Lee, J. K., Cho, S. Y., Murillo-Sauca, O. J., Uppaluri, R., … Sunwoo, J. B. (2017). CD271 Confers an Invasive and Metastatic Phenotype of Head and Neck Squamous Cell Carcinoma Through the Upregulation of Slug. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
The aryl hydrocarbon receptor modulates the function of human CD56bright NK cells.
Moreno-Nieves, U. Y., Mundy, D. C., Shin, J. H., Tam, K., & Sunwoo, J. B. (2018). The aryl hydrocarbon receptor modulates the function of human CD56bright NK cells. European Journal of Immunology. -
Assessing the Impact of Targeting CEACAM1 in Head and Neck Squamous Cell Carcinoma.
Tam, K., Schoppy, D. W., Shin, J. H., Tay, J. K., Moreno-Nieves, U., Mundy, D. C., & Sunwoo, J. B. (2018). Assessing the Impact of Targeting CEACAM1 in Head and Neck Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599818756627. -
Gene Expression in Nasopharyngeal Carcinoma by Laser Capture Microdissected Transcriptome Sequencing
Tay, J. K., Zhu, C., Sunwoo, J., Le, Q. T., & West, R. B. (2018). Gene Expression in Nasopharyngeal Carcinoma by Laser Capture Microdissected Transcriptome Sequencing. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 100(5), 1385. -
CEACAM1 blockade increases NK cell cytotoxicity in head and neck squamous cell carcinoma
Tam, K., Lee, Y., Schoppy, D., & Sunwoo, J. B. (2017). CEACAM1 blockade increases NK cell cytotoxicity in head and neck squamous cell carcinoma. CLINICAL CANCER RESEARCH, 23(23). -
Novel aldehyde dehydrogenase inhibitors as potential anti-chemoresistance drugs for head and neck cancers
Kim, J., Shin, J. H., Chen, C.-H., Cruz, L., Farnebo, L., Yang, J., … Mochly-Rosen, D. (2014). Novel aldehyde dehydrogenase inhibitors as potential anti-chemoresistance drugs for head and neck cancers. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Stimulation of natural killer cells with an anti-CD137 antibody enhances the efficacy trastuzumab, cetuximab, and rituximab in HER2-expressing breast cancer, EGFR plus head and neck cancer, and CD20+lymphoma
Kohrt, H., Houot, R., Weiskopf, K., Goldsteini, M., Lund, P., Czerwinski, D., … Levy, R. (2012). Stimulation of natural killer cells with an anti-CD137 antibody enhances the efficacy trastuzumab, cetuximab, and rituximab in HER2-expressing breast cancer, EGFR plus head and neck cancer, and CD20+lymphoma. CANCER RESEARCH, 72. -
Regionally Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck: Survival and High-Risk Features
Amoils, M., Lee, C. S., Sunwoo, J., Aasi, S. Z., Hara, W., Kim, J., … Divi, V. (2016). Regionally Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck: Survival and High-Risk Features. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
ERK1/2 regulation of CD44 modulates aggressiveness in a new mouse model of oral cancer
Uppaluri, R., Judd, N., Winkler, A., Law, J., Murillo-Sauca, O., & Sunwoo, J. (2012). ERK1/2 regulation of CD44 modulates aggressiveness in a new mouse model of oral cancer. CANCER RESEARCH, 72. -
A Pilot Study of Electronic Quality of Life Assessments Using Tablet Devices During and After Treatment of Head and Neck Cancers
Wang, E., Pollom, E., Bui, T., Ognibene, G., von Eyben, R., Divi, V., … Hara, W. (2016). A Pilot Study of Electronic Quality of Life Assessments Using Tablet Devices During and After Treatment of Head and Neck Cancers. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 94(4), 969. -
Survey of oral cancer screening participants reveals widespread misconceptions about oral cancer risk factors, independent of educational background
Chester, C., Sabile, J., Cho, G., Hu, A., Hamaguchi, R., Ellis, L., … Sunwoo, J. (2015). Survey of oral cancer screening participants reveals widespread misconceptions about oral cancer risk factors, independent of educational background. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Targeting CD137 to enhance the antitumor efficacy of cetuximab by stimulation of innate and adaptive immunity.
Kohrt, H. E., Houot, R., Weiskopf, K., Goldstein, M., Lund, P., Lira, R. R., … Levy, R. (2013). Targeting CD137 to enhance the antitumor efficacy of cetuximab by stimulation of innate and adaptive immunity. JOURNAL OF CLINICAL ONCOLOGY, 31(15). -
Enhancing NK cell-mediated tumor rejection by activation of the aryl hydrocarbon receptor
Sunwoo, J., Shin, J., Zhang, L., Murillo, O., & Kim, J. (2011). Enhancing NK cell-mediated tumor rejection by activation of the aryl hydrocarbon receptor. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in Adults.
Orloff, L. A., Wiseman, S., Bernet, V., Fahey, T. 3rd, Shaha, A. R., Shindo, M., … Wang, M. B. (2018). American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in Adults. Thyroid : Official Journal of the American Thyroid Association. -
PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma.
Amoils, M., Kim, J., Lee, C., Sunwoo, J. B., Colevas, A. D., Aasi, S. Z., … Divi, A. V. (2018). PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599818788057. -
Clinical perineural invasion of cutaneous head and neck cancer: Impact of radiotherapy, imaging, and nerve growth factor receptors on symptom control and prognosis.
Chen, J. J., Harris, J. P., Kong, C. S., Sunwoo, J. B., Divi, V., Horst, K. C., … Hara, W. Y. (2018). Clinical perineural invasion of cutaneous head and neck cancer: Impact of radiotherapy, imaging, and nerve growth factor receptors on symptom control and prognosis. Oral Oncology, 85, 60–67. -
Organoid Modeling of the Tumor Immune Microenvironment.
Neal, J. T., Li, X., Zhu, J., Giangarra, V., Grzeskowiak, C. L., Ju, J., … Kuo, C. J. (2018). Organoid Modeling of the Tumor Immune Microenvironment. Cell, 175(7), 1972. -
The immune subtypes and landscape of squamous cell carcinoma.
Li, B., Cui, Y., Nambiar, D. K., Sunwoo, J. B., & Li, R. (2019). The immune subtypes and landscape of squamous cell carcinoma. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Magnetic nanoparticles induced natural killer (NK) cell control to target tumor site
Oh, C. hyun, Shin, J.-H., Sunwoo, J., Cheng, Z., & Jang, E.-S. (2012). Magnetic nanoparticles induced natural killer (NK) cell control to target tumor site. JOURNAL OF NUCLEAR MEDICINE, 53. -
Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor.
Kim, J., Shin, J. H., Chen, C.-H. H., Cruz, L., Farnebo, L., Yang, J., … Sunwoo, J. B. (2017). Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor. Oncotarget, 8(32), 52345–52356. -
American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in Adults
Orloff, L. A., Wiseman, S. M., Bernet, V. J., Fahey, T. J., Shaha, A. R., Shindo, M. L., … Wang, M. B. (2018). American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in Adults. THYROID, 28(7), 830–41. -
Organoid Modeling of the Tumor Immune Microenvironment
Neal, J. T., Li, X., Zhu, J., Giangarra, V., Grzeskowiak, C. L., Ju, J., … Kuo, C. J. (2018). Organoid Modeling of the Tumor Immune Microenvironment. CELL, 175(7), 1972-+. -
Clinical perineural invasion of cutaneous head and neck cancer: Impact of radiotherapy, imaging, and nerve growth factor receptors on symptom control and prognosis
Chen, J. J., Harris, J. P., Kong, C. S., Sunwoo, J. B., Divi, V., Horst, K. C., … Hara, W. Y. (2018). Clinical perineural invasion of cutaneous head and neck cancer: Impact of radiotherapy, imaging, and nerve growth factor receptors on symptom control and prognosis. ORAL ONCOLOGY, 85, 60–67. -
PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma
Amoils, M., Kim, J., Lee, C., Sunwoo, J. B., Colevas, A. D., Aasi, S. Z., … Divi, V. (2019). PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 160(1), 93–99. -
Assessing the Impact of Targeting CEACAM1 in Head and Neck Squamous Cell Carcinoma
Tam, K., Schoppy, D. W., Shin, J. H., Tay, J. K., Moreno-Nieves, U., Mundy, D. C., & Sunwoo, J. B. (2018). Assessing the Impact of Targeting CEACAM1 in Head and Neck Squamous Cell Carcinoma. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. SAGE PUBLICATIONS LTD. -
The aryl hydrocarbon receptor modulates the function of human CD56(bright) NK cells
Moreno-Nieves, U. Y., Mundy, D. C., Shin, J. H., Tam, K., & Sunwoo, J. B. (2018). The aryl hydrocarbon receptor modulates the function of human CD56(bright) NK cells. EUROPEAN JOURNAL OF IMMUNOLOGY, 48(5), 771–76. -
Epigenetically Mediated Pathogenic Effects of Phenanthrene on Regulatory T Cells
Liu, J., Zhang, L., Winterroth, L. C., Garcia, M., Weiman, S., Wong, J. W., … Nadeau, K. C. (2013). Epigenetically Mediated Pathogenic Effects of Phenanthrene on Regulatory T Cells. JOURNAL OF TOXICOLOGY. -
Corrigendum to 'Clinical perineural invasion of cutaneous head and neck cancer: Impact of radiotherapy, imaging, and nerve growth factor receptors on symptom control and prognosis'. [Oral Oncol. 85 (2018) 60-67].
Chen, J. J., Harris, J. P., Kong, C. S., Sunwoo, J. B., Divi, V., Horst, K. C., … Hara, W. Y. (2019). Corrigendum to 'Clinical perineural invasion of cutaneous head and neck cancer: Impact of radiotherapy, imaging, and nerve growth factor receptors on symptom control and prognosis'. [Oral Oncol. 85 (2018) 60-67]. Oral Oncology. -
Biological subtypes of nasopharyngeal carcinoma by genomic profiling
Tay, K. X. J., Zhu, C., Vennam, S., Varma, S., Quynh-Thu Le, Sunwoo, J., & West, R. (2018). Biological subtypes of nasopharyngeal carcinoma by genomic profiling. CANCER RESEARCH, 78(13). -
NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma
Brennan, K., Gevaert, O., Sunwoo, J. B., & Shin, J. H. (2018). NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma. CANCER RESEARCH, 78(13). -
Post-transplant head and neck cancers: A prospective analysis of clinical factors for risk stratification.
Soo, J., Schroers-Martin, J., Garofalo, A., Kurtz, D. M., D'Emilio, N., & Grimm, D. R. (2018). Post-transplant head and neck cancers: A prospective analysis of clinical factors for risk stratification. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
The Immune Subtypes and Landscape of Squamous Cell Carcinoma
Li, B., Cui, Y., Nambiar, D. K., Sunwoo, J. B., & Li, R. (2019). The Immune Subtypes and Landscape of Squamous Cell Carcinoma. CLINICAL CANCER RESEARCH, 25(12), 3528–37. -
Natural Killer Cells and Thyroid Diseases.
Lee, E. K., & Sunwoo, J. B. (2019). Natural Killer Cells and Thyroid Diseases. Endocrinology and Metabolism (Seoul, Korea), 34(2), 132–37. -
Implementation of a targeted HPV educational program in a population with HIV.
Ayoub, N., Sunwoo, J. B., & Starmer, H. M. (2019). Implementation of a targeted HPV educational program in a population with HIV. World Journal of Otorhinolaryngology - Head and Neck Surgery, 5(2), 105–11. -
Lymph node colonization promotes distant tumor metastasis through the induction of systemic immune tolerance
Reticker-Flynn, N. E., Martins, M. M., Basto, P. A., Zhang, W., Bejnood, A., Gentles, A. J., … Engleman, E. G. (2019). Lymph node colonization promotes distant tumor metastasis through the induction of systemic immune tolerance. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
ERAP2 overexpression is a marker for reduced anti-PD-1 response in nasopharyngeal carcinoma.
Tay, J. K., Ma, B. B. Y., Varma, S., Lim, Y. C., Tan, C. S., Lo, K. W., … West, R. B. (2020). ERAP2 overexpression is a marker for reduced anti-PD-1 response in nasopharyngeal carcinoma. CANCER IMMUNOLOGY RESEARCH. AMER ASSOC CANCER RESEARCH. -
Exome scale liquid biopsy monitoring of putative neoantigens and genomic biomarkers in patients on anti-PD-1 therapy in squamous cell carcinoma of the head and neck.
Abbott, C. W., Bedi, N., Zhang, S. V., Li, R., Pyke, R. M., Levy, E., … Boyle, S. M. (2020). Exome scale liquid biopsy monitoring of putative neoantigens and genomic biomarkers in patients on anti-PD-1 therapy in squamous cell carcinoma of the head and neck. CANCER IMMUNOLOGY RESEARCH. AMER ASSOC CANCER RESEARCH. -
Managing the Head and Neck Cancer Patient with Tracheostomy or Laryngectomy During the COVID-19 Pandemic.
Kligerman, M. P., Vukkadala, N., Tsang, R. K., Sunwoo, J. B., Holsinger, F. C., Chan, J. Y., … Starmer, H. M. (2020). Managing the Head and Neck Cancer Patient with Tracheostomy or Laryngectomy During the COVID-19 Pandemic. Head & Neck. -
A Framework for Prioritizing Head and Neck Surgery during the COVID-19 Pandemic.
Topf, M. C., Shenson, J. A., Holsinger, F. C., Wald, S. H., Cianfichi, L. J., Rosenthal, E. L., & Sunwoo, J. B. (2020). A Framework for Prioritizing Head and Neck Surgery during the COVID-19 Pandemic. Head & Neck. -
Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immunosuppression.
Reticker-Flynn, N. E., Basto, P. A., Zhang, W., Bejnood, A., Kenkel, J. A., Martins, M. M., … Engleman, E. G. (2020). Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immunosuppression. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
High-resolution positron emission microscopy of patient-derived tumor organoids.
Khan, S., Shin, J. H., Cheng, N., Kuo, C., Sunwoo, J., & Pratx, G. (2020). High-resolution positron emission microscopy of patient-derived tumor organoids. CANCER RESEARCH, 80(11), 59. -
Application of salivary noncoding microRNAs for the diagnosis of oral cancers.
Deutsch, F. T., Khoury, S. J., Sunwoo, J. B., Elliott, M. S., & Tran, N. T. (2020). Application of salivary noncoding microRNAs for the diagnosis of oral cancers. Head & Neck. -
Association Between Immunosuppression and Outcomes in Oral Cavity Squamous Cell Carcinoma.
Chang, J., Sunwoo, J. B., Shah, J. L., Hara, W., Hong, J., Colevas, A. D., & Divi, V. (2020). Association Between Immunosuppression and Outcomes in Oral Cavity Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599820960146. -
Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma.
Parikh, A., Shin, J. H., Faquin, W., Lin, D. T., Tirosh, I., Sunwoo, J. B., & Puram, S. V. (2020). Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma. Journal for Immunotherapy of Cancer, 8(2). -
Exome scale liquid biopsy characterization of putative neoantigens and genomic biomarkers pre- and post anti-PD-1 therapy in squamous cell carcinoma of the head and neck.
Abbott, C., Bedi, N., Zhang, S., Li, R., Pyke, R., Levy, E., … Boyle, S. M. (2020). Exome scale liquid biopsy characterization of putative neoantigens and genomic biomarkers pre- and post anti-PD-1 therapy in squamous cell carcinoma of the head and neck. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee.
Gastman, B., Agarwal, P. K., Berger, A., Boland, G., Broderick, S., Butterfield, L. H., … Kaufman, H. L. (2020). Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee. Journal for Immunotherapy of Cancer, 8(2). -
Plasticity and Polarization of Human NK Cells in the Tumor Microenvironment
Nieves, U. Y. M., Tay, J., Saumyaa, S., Mundy, D., & Sunwoo, J. B. (2020). Plasticity and Polarization of Human NK Cells in the Tumor Microenvironment. JOURNAL OF IMMUNOLOGY, 204(1). -
Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immunosuppression
Reticker-Flynn, N. E., Basto, P. A., Zhang, W., Martins, M. M., Chang, S., Gentles, A. J., … Engleman, E. G. (2020). Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immunosuppression. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Sensitive HLA loss of heterozygosity detection reveals allele-specific neoantigen expansion as resistance mechanism to anti-PD-1 therapy
Pyke, R. M., Abbott, C., Mellacheruvu, D., Zhang, S., Bedi, N., Colevas, A. D., … Boyle, S. M. (2020). Sensitive HLA loss of heterozygosity detection reveals allele-specific neoantigen expansion as resistance mechanism to anti-PD-1 therapy. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
AHR Regulates NK Cell Migration via ASB2-Mediated Ubiquitination of Filamin A.
Shin, J. H., Moreno-Nieves, U. Y., Zhang, L. H., Chen, C., Dixon, A. L., Linde, M. H., … Sunwoo, J. B. (2021). AHR Regulates NK Cell Migration via ASB2-Mediated Ubiquitination of Filamin A. Frontiers in Immunology, 12, 624284. -
Humanized Mouse Models for the Advancement of Innate Lymphoid Cell-Based Cancer Immunotherapies.
Horowitz, N. B., Mohammad, I., Moreno-Nieves, U. Y., Koliesnik, I., Tran, Q., & Sunwoo, J. B. (2021). Humanized Mouse Models for the Advancement of Innate Lymphoid Cell-Based Cancer Immunotherapies. Frontiers in Immunology, 12, 648580. -
Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment.
Moreno-Nieves, U. Y., Tay, J. K., Saumyaa, S., Horowitz, N. B., Shin, J. H., Mohammad, I. A., … Sunwoo, J. B. (2021). Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America, 118(28). -
Pan-cancer survey of HLA loss of heterozygosity using a robustly validated NGS-based machine learning algorithm.
Pyke, R. M., Mellacheruvu, D., Abbott, C., Dea, S., Levy, E., Zhang, S. V., … Boyle, S. M. (2021). Pan-cancer survey of HLA loss of heterozygosity using a robustly validated NGS-based machine learning algorithm. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Longitudinal exome-scale liquid biopsy monitoring of evolving therapeutic resistance mechanisms in head and neck squamous cell carcinoma patients receiving anti-PD-1 therapy.
Abbott, C. W., Bedi, N., Zhang, S. V., Northcott, J., Li, R., Pyke, R. M., … Chen, R. (2021). Longitudinal exome-scale liquid biopsy monitoring of evolving therapeutic resistance mechanisms in head and neck squamous cell carcinoma patients receiving anti-PD-1 therapy. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Chromatin accessibility associates with protein-RNA correlation in human cancer.
Sanghi, A., Gruber, J. J., Metwally, A., Jiang, L., Reynolds, W., Sunwoo, J., … Snyder, M. P. (2021). Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications, 12(1), 5732. -
High-resolution positron emission microscopy of patient-derived tumor organoids.
Khan, S., Shin, J. H., Ferri, V., Cheng, N., Noel, J. E., Kuo, C., … Pratx, G. (2021). High-resolution positron emission microscopy of patient-derived tumor organoids. Nature Communications, 12(1), 5883. -
Association of HLA loss of heterozygosity with allele-specific neoantigen expansion in response to immunotherapy.
Pyke, R. M., Abbott, C., Dea, S., Bedi, N., Colevas, A. D., Levy, E., … Boyle, S. M. (2021). Association of HLA loss of heterozygosity with allele-specific neoantigen expansion in response to immunotherapy. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
NSD1 mutations deregulate transcription and DNA methylation of bivalent developmental genes in Sotos syndrome.
Brennan, K., Zheng, H., Fahrner, J. A., Shin, J. H., Gentles, A. J., Schaefer, B., … Gevaert, O. (2022). NSD1 mutations deregulate transcription and DNA methylation of bivalent developmental genes in Sotos syndrome. Human Molecular Genetics. -
The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-?B signaling.
Tay, J. K., Zhu, C., Shin, J. H., Zhu, S. X., Varma, S., Foley, J. W., … West, R. B. (2022). The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-?B signaling. Science Advances, 8(14), eabh2445. -
TUMOR-INFORMED LIQUID BIOPSY MONITORING OF EVOLVING THERAPEUTIC RESISTANCE MECHANISMS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA PATIENTS RECEIVING ANTI-PD-1 THERAPY
Abbott, C., Bedi, N., Wang, J., Northcott, J., Pyke, R., Li, R., … Chen, R. (2021). TUMOR-INFORMED LIQUID BIOPSY MONITORING OF EVOLVING THERAPEUTIC RESISTANCE MECHANISMS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA PATIENTS RECEIVING ANTI-PD-1 THERAPY. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
AI-ASSISTED WHOLE-BODY ASSESSMENT OF IMMUNOTHERAPY RESPONSE USING [18F]F-ARAG, A PET AGENT FOR ACTIVATED T CELLS
Levi, J., Perk, T., Huynh, L., Packiasamy, J., Cheng, S., Sunwoo, J., & Colevas, A. D. (2021). AI-ASSISTED WHOLE-BODY ASSESSMENT OF IMMUNOTHERAPY RESPONSE USING [18F]F-ARAG, A PET AGENT FOR ACTIVATED T CELLS. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
T CELL PHENOTYPE DRIVES RESTRUCTURING OF TUMOR MICROENVIRONMENT TO BALANCE T CELL LONGEVITY AND TUMOR CONTROL: INSIGHTS FROM MULTIPLEXED IMAGING AND MULTI-SCALE AGENT BASED MODELING
Hickey, J., Nolan, G., Covert, M., Agmon, E., Horowitz, N., & Sunwoo, J. (2021). T CELL PHENOTYPE DRIVES RESTRUCTURING OF TUMOR MICROENVIRONMENT TO BALANCE T CELL LONGEVITY AND TUMOR CONTROL: INSIGHTS FROM MULTIPLEXED IMAGING AND MULTI-SCALE AGENT BASED MODELING. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
INTRAEPITHELIAL GROUP 1 INNATE LYMPHOID CELLS GENERATED IN VITRO EXHIBIT ENHANCED CYTOTOXICITY AND INFILTRATION INTO SOLID TUMOROIDS
Horowitz, N., Hickey, J., & Sunwoo, J. (2021). INTRAEPITHELIAL GROUP 1 INNATE LYMPHOID CELLS GENERATED IN VITRO EXHIBIT ENHANCED CYTOTOXICITY AND INFILTRATION INTO SOLID TUMOROIDS. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Reticker-Flynn, N. E., Zhang, W., Belk, J. A., Basto, P. A., Escalante, N. K., Pilarowski, G. O., … Engleman, E. G. (2022). Lymph node colonization induces tumor-immune tolerance to promote distant metastasis. Cell. -
Emerging NK cell therapies for cancer and the promise of next generation engineering of iPSC-derived NK cells.
Maddineni, S., Silberstein, J. L., & Sunwoo, J. B. (2022). Emerging NK cell therapies for cancer and the promise of next generation engineering of iPSC-derived NK cells. Journal for Immunotherapy of Cancer, 10(5). -
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.
Zhang, W., Li, I., Reticker-Flynn, N. E., Good, Z., Chang, S., Samusik, N., … Plevritis, S. K. (2022). Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA. Nature Methods. -
BASECAMP-1: Leveraging human leukocyte antigen (HLA) loss of heterozygosity (LOH) in solid tumors by next-generation sequencing (NGS) to identify patients with relapsed solid tumor for future logic-gated Tmod CAR T-cell therapy
Simeone, D. M., Hecht, J. R., Patel, S. P., Morelli, M. P., Kirtane, K., Borad, M. J., … Molina, J. R. (2022). BASECAMP-1: Leveraging human leukocyte antigen (HLA) loss of heterozygosity (LOH) in solid tumors by next-generation sequencing (NGS) to identify patients with relapsed solid tumor for future logic-gated Tmod CAR T-cell therapy. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Genomic Immune Evasion: Diagnostic and Therapeutic Opportunities in Head and Neck Squamous Cell Carcinomas.
Kirtane, K., St John, M., Fuentes-Bayne, H., Patel, S. P., Mardiros, A., Xu, H., … Welch, J. S. (2022). Genomic Immune Evasion: Diagnostic and Therapeutic Opportunities in Head and Neck Squamous Cell Carcinomas. Journal of Clinical Medicine, 11(24). -
NFE2L2 mutations enhance radioresistance in head and neck cancer by modulating intratumoral myeloid cells.
Guan, L., Nambiar, D. K., Cao, H., Viswanathan, V., Kwok, S., Hui, A. B., … Le, Q.-T. T. (2023). NFE2L2 mutations enhance radioresistance in head and neck cancer by modulating intratumoral myeloid cells. Cancer Research. -
BASECAMP-1: LEVERAGING HLA LOSS OF HETEROZYGOSITY IN SOLID TUMORS BY NGS TO IDENTIFY PATIENTS WITH RELAPSED SOLID TUMORS FOR FUTURE CEA AND MSLN LOGIC-GATED TMOD (TM) CAR T-CELL THERAPY
Simeone, D., Morelli, M. P., Hecht, J. R., Patel, S., Fakih, M., Kirtane, K., … Molina, J. (2022). BASECAMP-1: LEVERAGING HLA LOSS OF HETEROZYGOSITY IN SOLID TUMORS BY NGS TO IDENTIFY PATIENTS WITH RELAPSED SOLID TUMORS FOR FUTURE CEA AND MSLN LOGIC-GATED TMOD (TM) CAR T-CELL THERAPY. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
7-UP: Generating in silico CODEX from a small set of immunofluorescence markers.
Wu, E., Trevino, A. E., Wu, Z., Swanson, K., Kim, H. J., D'Angio, H. B., … Zou, J. (2023). 7-UP: Generating in silico CODEX from a small set of immunofluorescence markers. PNAS Nexus, 2(6), pgad171. -
Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma.
Chen, C., Shin, J. H., Fang, Z., Brennan, K., Horowitz, N. B., Pfaff, K. L., … Sunwoo, J. B. (2023). Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma. Cancer Research. -
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Nigam, N., Bernard, B., Sevilla, S., Kim, S., Dar, M. S., Tsai, D., … Saloura, V. (2023). SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck. Cell Reports, 42(7), 112823. -
Racial Disparities in 30-day Readmissions after Surgery for Head and Neck Cancer.
Huang, A. E., Shih, J. J., Sunwoo, J. B., Pollom, E., & Taparra, K. (2023). Racial Disparities in 30-day Readmissions after Surgery for Head and Neck Cancer. The Laryngoscope. -
Oral cavity cancer in young, non-smoking, and non-drinking patients: a contemporary review.
Tran, Q., Maddineni, S., Arnaud, E. H., Divi, V., Megwalu, U., Topf, M. C., & Sunwoo, J. B. (2023). Oral cavity cancer in young, non-smoking, and non-drinking patients: a contemporary review. Critical Reviews in Oncology/Hematology, 104112. -
Single institution validation of a sentinel lymph node biopsy risk prediction tool for cutaneous melanoma
Muralidharan, V., Maddineni, S., Young, L., Sunwoo, J., Baik, F. M., & Swetter, S. (2023). Single institution validation of a sentinel lymph node biopsy risk prediction tool for cutaneous melanoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. ELSEVIER SCIENCE INC. -
Toll-like Receptor Agonists Are Unlikely to Provide Benefits in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
Maddineni, S., Chen, M., Baik, F., Divi, V., Sunwoo, J. B., & Finegersh, A. (2023). Toll-like Receptor Agonists Are Unlikely to Provide Benefits in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. Cancers, 15(17).
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Imaging and Biomarkers of Hypoxia in Solid Tumors »
- Panitumumab IRDye800 Optical Imaging Study »
- Multispectral Imaging to Characterize Patterns of Vascular Supply Within Lymphoepithelial Mucosa in Oropharyngeal Cancer »
- Study to Evaluate Immunological Response to PD-1 Inhibition in Squamous Cell Carcinoma of the Head and Neck (SCCHN) »
- Cetuximab IRDye800 Study as an Optical Imaging Agent to Detect Cancer During Surgical Procedures »
- Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer or Squamous Cell Head and Neck Cancer »
Practice Locations
Stanford Pigmented Lesion and Melanoma Program at Stanford Cancer Center Palo Alto Palo Alto, CA
Palo Alto, CA
Stanford Pigmented Lesion and Melanoma Program at Stanford Cancer Center Palo Alto
900 Blake Wilbur Drive, 3rd Floor
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Head and Neck Cancer Program at 900 Blake Wilbur Palo Alto, CA
Palo Alto, CA
Head and Neck Cancer Program at 900 Blake Wilbur
900 Blake Wilbur Drive
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Important Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Patient Reviews
(76 reviews)
I am very grateful for all the help provided by Dr. Sweater and Dr. Sunwoo and All the interns and helpers. Please let them them know of my great gratitudemy
very professional and thorough
Doctor sunwood seems very thorough to me
Dr Sun-Woo is the best doctor on the planet. I feel lucky that I’m able.to see him for my cancer check ups. He is a master with the laryngeal scope and I’ve had quite a few doctors perform that procedure on me. He is very caring to his patients needs and just an all around good human being. He’s 5 stars in my book
Dr. Sunwoo is the most caring and knowledgeable doctor I have ever seen! He takes time to explain everything in a manner that is easy to understand, and he never rushes me out of the room or off the video call without continually asking if I have any other questions. I am so thankful and feel like the luckiest patient!
Every aspect of the visit went smoothly, including check in, interaction with nurse & exam with dr sun woo & other doctor.
very professional at all levels
Wonderful Doctor and assistant physician.
Excellent, as usual---
The latest in treatments and extremely high quality staff.
Dr, Sunwoo, great doctor, anwers all my question, took all the time I needed,
I am so impressed and so thankful for Dr. Sunwoo and his team. Excellent, and put me so at ease after speaking with Dr. Sunwoo.
Second visit much improved over initial visit. Much more focused on the issues. Thank you.
Dr. Sunwoo is patient, kind and was interested in the questions I asked and was happy to provide an answer to each of them. I didn't feel rushed at all. He was supported by a nurse and radiologic tech I believe to help me see what the mri revealed.
Both Doctor Sun Woo and the resident who saw me were patient, gentle, listened to my concerns, thorough,, explained a procedure that was recommended and why, and above all else made be feel like I was the most important patient they had ever seen. Truly one of the best doctor appointments I have ever had in any category!
Wait time was fast. Great positive attitude from the doctor. Questions answered by doctor. I forgot to set up next appt but it was set up automatically by the team. Great service and attention.
excellent service,
Dr. Subwoo was fantastic, he answered all my questions and provided a comprehensive explanation.
Very detailed
Detailed, warm, patience and listen
Dr. Sunwoo was very good & listened to me.
you guys are the best!
my health concerns met with optimum provisions
Dr. Sunwoo is always caring & concerned.
Dr. Sunwoo is a wonderful, thoughtful, caring doctor. I feel very fortunate to have him for my doctor.
The "go to" provider.
Dr. Sunwoo is gentle, has a very calming effect - that's a good thing. Answers all my questions, so I can understand.
Dr. Sunwoo has an outstanding bedside manner, very inclusive, valued my input, provided options he was genuine, caring, empathetic, & compassionate about his work, I felt very confident about his work to care for me & treatment.
I can't say enough about the thoughtful, intelligent and warm care I received!
Great doctor. Good experience.
Great professional, eminence offered much love & tranquil spirit.
Dr. Sunwoo & staff are excellent!
Good experience. Dr. very good.
Dr. Sunwoo is an excellent doctor who had great patience and is very meticulous and thorough.
Before having referred to Stanford for thyroid cancer, I had many tests & providers in my local area. At Stanford I saw true competence & professionalism for the first time. Wish I lived closer so I could have all my medical needs taken care of there.
Good experience.
I have been most satisfied with Dr. John Sunwoo. He is very thorough and explains procedures very well. He is a true asset to Stanford Health Care.
Dr. Sunwoo has been my follow up physician since Dr. Fe retired. I have complete confidence in him.
The doctor (Dr. Sunwoo) was very clear in explaining what will happen & what will be done to the patient.
I do recommend. May God bless the dr.
Excellent...
Excellent.
Everyone - From arrival to MD - Terrific!
Explained what was going to happen and I could understand what was being said.
I recommend Stanford to anyone I know regularly.
The medical staff was the most informed and, all around, professional I have ever met.
Dr. explain the problem clearly.
Dr. Sunwoo is very caring genuine physician.
Very inspiring and hopeful thank you.
Dr. Sunwoo made a very scary experience easy. He is the best!
All who cared for me were excellent.
Doctor Sunwood went out of his way to see me and accommodate my schedule in treatment.
Dr. Sunwoo & staff are outstanding.
Dr. John Sunwoo is very friendly, his explanation about my problem were easy to understand. I have complete confidence in Dr. Sunwoo. I would recommend him to others. Zoya Benjamin, PA, also does a great job.
If this staff is any example of the rest of the hospital we wish we lived closer to have the best of our needs cared for.
A great doctor.
Thanks to Dr. Sunwood John Bing, great skills and professional, and nice like an angel!
Super.
I recommend it because they took very good care of me.
Dr. Sunwoo and my whole team are wonderful!! Love them!
Excellent!
As always, Dr. Sunwood and staff were great!!
I have given Dr. Sunwoo 5's in every area. He is beyond "very good"; he is outstanding as a care provider.
Wish that doctor himself had come to see me and answer my questions before I was discharged from the hospital.
Dr. Sunwoo never seems to be in a hurry. He is a great dr. and does beautiful work.
Could not ask for more.
I'm very pleased.
My care under Dr. Sunwoo has been excellent.
Good.
Very concerned about follow-on care.
Dr. Sunwoo is an all around FABULOUS dr.!
The PA took so much time with us and spoke so well of the doctor. PA also shared some info and encouragement that the doctor eventually shared.
Dr. Sunwoo was kind & positive about a scary medical condition one of the best drs. I've ever been to.
Care provided was excellent! Thank you.
I was very impressed with Dr. Sunwoo. He was so clear in his explanation of my health care & problem.
Long drive and limited available scheduling.
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Referring Physicians
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