Trial ID or NCT#

NCT02959944

Status

RECRUITING

Purpose

To evaluate the safety and efficacy of ibrutinib in combination with prednisone in subjects with newly diagnosed moderate to severe cGVHD.

Official Title

Ibrutinib in Combination With Corticosteroids Versus Placebo in Combination With Corticosteroids in Subjects With New Onset Chronic Graft Versus Host Disease (cGVHD) (INTEGRATE)

Eligibility Criteria

Ages Eligible for Study: Older than 12 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
View All Criteria

Investigator(s)

David Miklos, M.D., Ph.D.
Blood and marrow transplant specialist, Blood and marrow transplant specialist, Hematologist, Medical oncologist
Associate Professor of Medicine (Blood and Marrow Transplantation) at the Stanford University Medical Center
Laura Johnston, MD
Blood and marrow transplant specialist, Blood and marrow transplant specialist, Medical oncologist, Hematologist
Associate Professor of Medicine (Blood and Marrow Transplantation) at the Stanford University Medical Center
Robert Negrin, M.D.
Blood and marrow transplant specialist, Hematologist, Blood and marrow transplant specialist
Professor of Medicine (Blood and Marrow Transplantation)
Wen-Kai Weng, MD, PhD
Blood and marrow transplant specialist, Blood and marrow transplant specialist, Lymphoma specialist, Medical oncologist, Multiple myeloma specialist
Associate Professor of Medicine (Blood and Marrow Transplantation) and, by courtesy, of Dermatology at the Stanford University Medical Center
Robert Lowsky, MD
Blood and marrow transplant specialist, Hematologist, Blood and marrow transplant specialist
Professor of Medicine (Blood and Marrow Transplantation) at the Stanford University Medical Center
Lori Muffly, MD, MS
Hematologist, Blood and marrow transplant specialist
Clinical Assistant Professor, Medicine - Blood & Marrow Transplantation

Contact us to find out if this trial is right for you.

CONTACT

Janet McDowell
(650) 725-1647

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View on ClinicalTrials.gov