Tina Cowan

Associate Professor of Pathology and, by courtesy, of Pediatrics (Genetics) at the Stanford University Medical Center

Professional Education

Fellowship: University of Maryland Baltimore

University of California Los Angeles School of Medicine (1986) CA

Board Certification: Medical Biochemical Genetics, American Board of Medical Genetics (1990)

Board Certification: Medical Genetics, American Board of Medical Genetics (1990)

B.A., UCLA, Biology (1979)

Ph.D., UCLA, Genetics (1986)

Administrative Appointments

Board of Directors, American Board of Medical Genetics (2006 - 2011)

Laboratory Quality Assurance Committee, American College of American Genetics (2003 - 2007)

Faculty Senate, Stanford University School of Medicine (2005 - 2008)

Committee on Courses and Curriculum, Stanford University School of Medicine (2006 - Present)

Degree of Glutathione Deficiency and Redox Imbalance Depend on Subtype of Mitochondrial Disease and Clinical Status
Enns, G. M., Moore, T., Le, A., Atkuri, K., Shah, M. K., & Cowan, T. M. (2014). Degree of Glutathione Deficiency and Redox Imbalance Depend on Subtype of Mitochondrial Disease and Clinical Status. PLOS ONE, 9(6).

A rapid, sensitive method for quantitative analysis of underivatized amino acids by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Le, A., Ng, A., Kwan, T., Cusmano-Ozog, K., & Cowan, T. M. (2014). A rapid, sensitive method for quantitative analysis of underivatized amino acids by liquid chromatography-tandem mass spectrometry (LC-MS/MS). JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 944, 166-174.

A new LC-MS/MS method for the clinical determination of reduced and oxidized glutathione from whole blood
Moore, T., Le, A., Niemi, A.-K., Kwan, T., Cusmano-Ozog, K., & Cowan, T. M. (2013). A new LC-MS/MS method for the clinical determination of reduced and oxidized glutathione from whole blood. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 929, 51-55.

Liver transplantation for urea cycle disorders in pediatric patients: A single-center experience
Kim, I. K., Niemi, A.-K., Krueger, C., Bonham, C. A., Concepcion, W., & Esquivel, C. O. (2013). Liver transplantation for urea cycle disorders in pediatric patients: A single-center experience. PEDIATRIC TRANSPLANTATION, 17(2), 158-167.

ß-Galactosidosis in Patient with Intermediate GM1 and MBD Phenotype.
Moore, T., Bernstein, J. A., Casson-Parkin, S., & Cowan, T. M. (2013). ß-Galactosidosis in Patient with Intermediate GM1 and MBD Phenotype. JIMD reports, 7, 77-79.

Increased incidence of profound biotinidase deficiency among Hispanic newborns in California
Cowan, T. M., Kazerouni, N. N., Dharajiya, N., Lorey, F., Roberson, M., & Schrijver, I. (2012). Increased incidence of profound biotinidase deficiency among Hispanic newborns in California. MOLECULAR GENETICS AND METABOLISM, 106(4), 485-487.

An improved LC-MS/MS method for the detection of classic and low excretor glutaric acidemia type 1
Moore, T., Le, A., & Cowan, T. M. (2012). An improved LC-MS/MS method for the detection of classic and low excretor glutaric acidemia type 1. JOURNAL OF INHERITED METABOLIC DISEASE, 35(3), 431-435.

A Novel Mutation in the HSD17B10 Gene of a 10-Year-Old Boy with Refractory Epilepsy, Choreoathetosis and Learning Disability
Seaver, L. H., He, X.-Y., Abe, K., Cowan, T., Enns, G. M., & Yang, S.-Y. (2011). A Novel Mutation in the HSD17B10 Gene of a 10-Year-Old Boy with Refractory Epilepsy, Choreoathetosis and Learning Disability. PLOS ONE, 6(11).

The role of vanin-1 and oxidative stress-related pathways in distinguishing acute and chronic pediatric ITP
Zhang, B., Lo, C., Shen, L., Sood, R., Jones, C., & Zehnder, J. L. (2011). The role of vanin-1 and oxidative stress-related pathways in distinguishing acute and chronic pediatric ITP. BLOOD, 117(17), 4569-4579.

Commentary.
Cowan, T. M. (2011). Commentary. Clinical chemistry, 57(4), 548-549.

Technical standards and guidelines for the diagnosis of biotinidase deficiency
Cowan, T. M., Blitzer, M. G., & Wolf, B. (2010). Technical standards and guidelines for the diagnosis of biotinidase deficiency. GENETICS IN MEDICINE, 12(7), 464-470.

Mapping Gene Associations in Human Mitochondria using Clinical Disease Phenotypes
Scharfe, C., Lu, H. H.-S., Neuenburg, J. K., Allen, E. A., Li, G.-C., & Davis, R. W. (2009). Mapping Gene Associations in Human Mitochondria using Clinical Disease Phenotypes. PLOS COMPUTATIONAL BIOLOGY, 5(4).

Clinical and Molecular Heterogeneity in Patients with the CblD Inborn Error of Cobalamin Metabolism
Miousse, I. R., Watkins, D., Coelho, D., Rupar, T., Crombez, E. A., & Rosenblatt, D. S. (2009). Clinical and Molecular Heterogeneity in Patients with the CblD Inborn Error of Cobalamin Metabolism. JOURNAL OF PEDIATRICS, 154(4), 551-556.

Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia
Atkuri, K. R., Cowan, T. M., Kwan, T., Ng, A., Herzenberg, L. A., & Enns, G. M. (2009). Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(10), 3941-3945.

Management and quality assurance in the biochemical genetics laboratory.
Cowan, T. M., & Strovel, E. T. (2008). Management and quality assurance in the biochemical genetics laboratory. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.], Chapter 17, Unit 17 7-?.

Progressive cerebral vascular degeneration with mitochondrial encephalopathy
Longo, N., Schrijver, I., Vogel, H., Pique, L. M., Cowan, T. M., & Enns, G. M. (2008). Progressive cerebral vascular degeneration with mitochondrial encephalopathy. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 146A(3), 361-367.

Acylcarnitine profile analysis
Rinaldo, P., Cowan, T. M., & Matern, D. (2008). Acylcarnitine profile analysis. GENETICS IN MEDICINE, 10(2), 151-156.

Importance of culturing primary lymphocytes at physiological oxygen levels
Atkuri, K. R., Herzenberg, L. A., Niemi, A.-K., Cowan, T., & Herzenberg, L. A. (2007). Importance of culturing primary lymphocytes at physiological oxygen levels. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(11), 4547-4552.

Glutaryl-CoA dehydrogenase deficiency and newborn screening: Retrospective analysis of a low excretor provides further evidence that some cases may be missed
Gallagher, R. C., Cowan, T. M., Goodman, S. I., & Enns, G. A. (2005). Glutaryl-CoA dehydrogenase deficiency and newborn screening: Retrospective analysis of a low excretor provides further evidence that some cases may be missed. MOLECULAR GENETICS AND METABOLISM, 86(3), 417-420.