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Biography
Dr. Bhati is an interventional psychiatrist with expertise in psychiatric diagnosis, psychopharmacology, and neuromodulation. He completed postdoctoral research studying language abnormalities and transcranial magnetic stimulation (TMS) evoked potentials in schizophrenia. He was a principal investigator for the DSM-5 academic field trials, and his research experiences included roles as an investigator in the first controlled clinical trials of deep brain stimulation (DBS) and low-field synchronized TMS for treatment of depression. His current interests include studying magnetic resonance imaging (MRI) and augmented reality to target TMS, vagus nerve stimulation (VNS) for treatment-resistant depression, responsive neurostimulation (RNS) for treatment of impulse and fear-related disorders, and focused ultrasound (FUS) for treatment-resistant obsessive compulsive disorder and depression. Dr. Bhati is also interested in better understanding consciousness and its role in mental illness.
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Professional Summary
Professional Education
- Postdoctoral research, University of Pennyslvania, Neuropsychiatry (2007)
- Residency, University of Pennsylvania, Psychiatry (research track) (2005)
- Medical Education: Louisiana State University Health Sciences Center Registrar (2001) LA
- B.S., Emory University, Biology (1996)
- B.A., Emory University, Chemistry (1996)
Honors & Awards
- Clinical Research Scholar, National Institutes of Health (2002-2005)
- Earl Bond Award, University of Pennsylvania Department of Psychiatry (2013)
- Health Care Hero, University of Pennsylvania Health System (2014)
- Innovator Grant Award, Stanford University Department of Psychiatry (2018)
- Irma Bland Award for Excellence in Teaching Residents, American Psychiatric Association (2012)
- Junior Investigator Grant Award, University of Pennsylvania (2007)
- Ruth L. Kirschstein National Research Service Award, National Institutes of Health (2005-2007)
- Stunkard Faculty Award, University of Pennsylvania Department of Psychiatry (2010)
- Travel Fellowship Award, Society of Biological Psychiatry (2006)
Administrative Appointments
- Director of Electroconvulsive Therapy, Stanford University Hospital (2016 - 2022)
- Section Chief of Interventional Psychiatry, Stanford University (2016 - 2022)
- Training Director, Interventional Psychiatry Fellowship, Stanford University Hospital (2021 - Present)
Publications
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The brain, language, and schizophrenia.
Bhati, M. T. (2005). The brain, language, and schizophrenia. Current Psychiatry Reports, 7(4), 297–303. -
Clinical manifestations, diagnosis, and empirical treatments for catatonia.
Bhati, M. T., Datto, C. J., & O'Reardon, J. P. (2007). Clinical manifestations, diagnosis, and empirical treatments for catatonia. Psychiatry (Edgmont (Pa. : Township)), 4(3), 46–52. -
Facial emotion recognition in schizophrenia: When and why does it go awry?
Turetsky, B. I., Kohler, C. G., Indersmitten, T., Bhati, M. T., Charbonnier, D., & Gur, R. C. (2007). Facial emotion recognition in schizophrenia: When and why does it go awry? SCHIZOPHRENIA RESEARCH, 94(1-3), 253–263. -
Effect of retrieval effort and switching demand on fMRI activation during semantic word generation in schizophrenia
Ragland, J. D., Moelter, S. T., Bhati, M. T., Valdez, J. N., Kohlerc, C. G., Siegel, S. J., … Gur, R. E. (2008). Effect of retrieval effort and switching demand on fMRI activation during semantic word generation in schizophrenia. SCHIZOPHRENIA RESEARCH, 99(1-3), 312–323. -
Defining Psychosis: The Evolution of DSM-5 Schizophrenia Spectrum Disorders
Bhati, M. T. (2013). Defining Psychosis: The Evolution of DSM-5 Schizophrenia Spectrum Disorders. CURRENT PSYCHIATRY REPORTS, 15(11). -
A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression
Dougherty, D. D., Rezai, A. R., Carpenter, L. L., Howland, R. H., Bhati, M. T., O'Reardon, J. P., … Malone, D. A. (2015). A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression. BIOLOGICAL PSYCHIATRY, 78(4), 240–248. -
Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression
Leuchter, A. F., Cook, I. A., Feifel, D., Goethe, J. W., Husain, M., Carpenter, L. L., … George, M. S. (2015). Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression. BRAIN STIMULATION, 8(4), 787–794. -
Catatonia and prediction of response to ECT
Caroff, S. N., Ungvari, G. S., Bhati, M. T., Datto, C. J., & O'Reardon, J. P. (2007). Catatonia and prediction of response to ECT. Psychiatric Annals, 32(1). -
What makes aripiprazole the ‘different’ antipsychotic.
Bhati, M. T. (2005). What makes aripiprazole the ‘different’ antipsychotic. Current Psychiatry, 4(7). -
Cognitive outcome after ventral capsule/ventral striatum stimulation for treatment-resistant major depression.
Kubu, C. S., Brelje, T., Butters, M. A., Deckersbach, T., Malloy, P., Moberg, P., … Malone, D. A. (2016). Cognitive outcome after ventral capsule/ventral striatum stimulation for treatment-resistant major depression. Journal of Neurology, Neurosurgery, and Psychiatry. -
A naturalistic, multi-site study of repetitive transcranial magnetic stimulation therapy for depression.
Taylor, S. F., Bhati, M. T., Dubin, M. J., Hawkins, J. M., Lisanby, S. H., Morales, O., … Wright, J. (2016). A naturalistic, multi-site study of repetitive transcranial magnetic stimulation therapy for depression. Journal of Affective Disorders, 208, 284–290. -
Deep Brain Stimulation for Alzheimer's Disease: Ethical Challenges for Clinical Research.
Siegel, A. M., Barrett, M. S., & Bhati, M. T. (2017). Deep Brain Stimulation for Alzheimer's Disease: Ethical Challenges for Clinical Research. Journal of Alzheimer's Disease : JAD, 56(2), 429–39. -
A Commentary on Attitudes Towards Deep Brain Stimulation for Addiction.
Lee, K. E., Bhati, M. T., & Halpern, C. H. (2016). A Commentary on Attitudes Towards Deep Brain Stimulation for Addiction. Journal of Neurology & Neuromedicine, 1(8), 1–3. -
Deciphering deep brain stimulation for depression.
Bhati, M. T., & Halpern, C. H. (2017). Deciphering deep brain stimulation for depression. The Lancet. Psychiatry. -
Naturalistic Clinical Monitoring of rTMS-Induced Plasticity With TMS-EEG
Keller, C., Wu, W., Sarhadi, K., Zhang, Y., Kerwin, L., Bhati, M., & Etkin, A. (2018). Naturalistic Clinical Monitoring of rTMS-Induced Plasticity With TMS-EEG. BIOLOGICAL PSYCHIATRY, 83(9), S195. -
MR-Guided Focused Ultrasound Versus Radiofrequency Capsulotomy for Treatment-Refractory Obsessive-Compulsive Disorder: A Cost-Effectiveness Threshold Analysis
Kumar, K. K., Bhati, M. T., Ravikumar, V. K., Ghanouni, P., Stein, S. C., & Halpern, C. H. (2019). MR-Guided Focused Ultrasound Versus Radiofrequency Capsulotomy for Treatment-Refractory Obsessive-Compulsive Disorder: A Cost-Effectiveness Threshold Analysis. FRONTIERS IN NEUROSCIENCE, 13. -
Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study
Kumar, K. K., Appelboom, G., Lamsam, L., Caplan, A. L., Williams, N. R., Bhati, M. T., … Halpern, C. H. (2019). Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 90(4), 469–73. -
Adjunctive repetitive transcranial magnetic stimulation delivers superior quality of life for focal epilepsy compared to anti-epileptic drugs: A meta-analytic utility prediction study.
Mahajan, U. V., Parker, J. J., Williams, N. R., Bhati, M. T., Ku, S., Grant, G., … Halpern, C. H. (2019). Adjunctive repetitive transcranial magnetic stimulation delivers superior quality of life for focal epilepsy compared to anti-epileptic drugs: A meta-analytic utility prediction study. Brain Stimulation. -
Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study.
Wu, H., Adler, S., Azagury, D. E., Bohon, C., Safer, D. L., Barbosa, D. A., … Halpern, C. H. (2020). Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study. Neurosurgery. -
Decreased Speech Coherence Captured by Novel Natural Language Processing Methods in Two Cohorts of Individuals With Schizophrenia
Tang, S., Kriz, R., Cho, S., Sedoc, J., Park, S. J., Harowitz, J., … Liberman, M. (2020). Decreased Speech Coherence Captured by Novel Natural Language Processing Methods in Two Cohorts of Individuals With Schizophrenia. BIOLOGICAL PSYCHIATRY, 87(9), S379–S380. -
Brain Stimulation Therapies
Keller, C., Bhati, M. T., Downar, J., & Etkin, A. (2019). Brain Stimulation Therapies. AMERICAN PSYCHIATRIC ASSOCIATION PUBLISHING TEXTBOOK OF PSYCHIATRY, 7TH EDITION, 861–98. -
Comparison of head pose tracking methods for mixed-reality neuronavigation for transcranial magnetic stimulation
Sathyanarayana, S., Leuze, C., Hargreaves, B., Daniel, B. L., Wetzstein, G., Etkin, A., … McNab, J. A. (2020). Comparison of head pose tracking methods for mixed-reality neuronavigation for transcranial magnetic stimulation. SPIE Medical Imaging. -
Natural language processing methods are sensitive to sub-clinical linguistic differences in schizophrenia spectrum disorders.
Tang, S. X., Kriz, R., Cho, S., Park, S. J., Harowitz, J., Gur, R. E., … Liberman, M. Y. (2021). Natural language processing methods are sensitive to sub-clinical linguistic differences in schizophrenia spectrum disorders. NPJ Schizophrenia, 7(1), 25. -
Deep Transcranial Magnetic Stimulation Combined With Brief Exposure for Posttraumatic Stress Disorder: A Prospective Multisite Randomized Trial.
Isserles, M., Tendler, A., Roth, Y., Bystritsky, A., Blumberger, D. M., Ward, H., … Ressler, K. J. (2021). Deep Transcranial Magnetic Stimulation Combined With Brief Exposure for Posttraumatic Stress Disorder: A Prospective Multisite Randomized Trial. Biological Psychiatry. -
Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression: A Decade of Clinical Follow-Up.
Hitti, F. L., Cristancho, M. A., Yang, A. I., O'Reardon, J. P., Bhati, M. T., & Baltuch, G. H. (2021). Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression: A Decade of Clinical Follow-Up. The Journal of Clinical Psychiatry, 82(6). -
National Network of Depression Centers' Recommendations on Harmonizing Clinical Documentation of Electroconvulsive Therapy.
Zandi, P. P., Morreale, M., Reti, I. M., Maixner, D. F., McDonald, W. M., Patel, P. D., … Weiner, R. D. (2022). National Network of Depression Centers' Recommendations on Harmonizing Clinical Documentation of Electroconvulsive Therapy. The Journal of ECT. -
Aberrant impulse control circuitry in obesity.
Barbosa, D. A., Kuijper, F. M., Duda, J., Wang, A. R., Cartmell, S. C., Saluja, S., … Halpern, C. H. (2022). Aberrant impulse control circuitry in obesity. Molecular Psychiatry. -
Interventional Neuropsychiatry
Coetzee, J. P., Kratter, I. H., Bhati, M. T., & Williams, N. R. (2022). Interventional Neuropsychiatry. Concise Guide to Neuropsychiatry and Behavioral Neurology (pp. 439–449). American Psychiatric Association Publishing. -
Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating.
Shivacharan, R. S., Rolle, C. E., Barbosa, D. A., Cunningham, T. N., Feng, A., Johnson, N. D., … Halpern, C. H. (2022). Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating. Nature Medicine.
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