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Specializing In
- Epilepsy
- Epilepsy Clinical and Translational Research
- Epilepsy Genetics
Biography
Dr. Li is a board-certified, fellowship-trained neurologist and a clinical assistant professor in the Department of Neurology and Neurological Sciences at Stanford University School of Medicine.
She specializes in epilepsy care and research. She has dedicated her career to advancing our understanding of the mechanism, diagnosis, and treatment of epilepsy. In addition to her MD degree, she holds a PhD degree in neurology and neuroscience. She undertook PhD training to better understand epileptogenesis and to identify potential new treatments for refractory epilepsy patients. She has received the Stanford Genetics and Genomics Certificate, which helped advance her knowledge of how genomic data can enhance patient management in clinical practice.
She has published numerous articles on a wide range of epilepsy-related topics. Among her honors, Dr. Li has earned recognition from the American Epilepsy Society and International League Against Epilepsy. She also won a safety and quality awards scholarship from the American Academy of Neurology. She is a member of the American Academy of Neurology and the American Epilepsy Society.
She specializes in epilepsy care and research. She has dedicated her career to advancing our understanding of the mechanism, diagnosis, and treatment of epilepsy. In addition to her MD degree, she holds a PhD degree in neurology and neuroscience. She undertook PhD training to better understand epileptogenesis and to identify potential new treatments for refractory epilepsy patients. She has received the Stanford Genetics and Genomics Certificate, which helped advance her knowledge of how genomic data can enhance patient management in clinical practice.
She has published numerous articles on a wide range of epilepsy-related topics. Among her honors, Dr. Li has earned recognition from the American Epilepsy Society and International League Against Epilepsy. She also won a safety and quality awards scholarship from the American Academy of Neurology. She is a member of the American Academy of Neurology and the American Epilepsy Society.
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Professional Summary
Education & Certifications
- Board Certification: American Board of Psychiatry and Neurology, Epilepsy (2020)
- Fellowship: Stanford University Epilepsy Fellowship (2020) CA
- Board Certification: American Board of Psychiatry and Neurology, Neurology (2018)
- Residency: University of Massachusetts GME Office (2018) MA
- Internship: University of Massachusetts Internal Medicine Residency (2015) MA
- Medical Education: Xiangya School of Medicine South University (2007) China
Publications
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Activation of ERK by spontaneous seizures in neural progenitors of the dentate gyrus in a mouse model of epilepsy
Li, Y., Peng, Z., Xiao, B., & Houser, C. R. (2010). Activation of ERK by spontaneous seizures in neural progenitors of the dentate gyrus in a mouse model of epilepsy. EXPERIMENTAL NEUROLOGY, 224(1), 133–45. -
Electroencephalography of Seizure-Like Movements During General Anesthesia with Propofol: Seizures or Nonepileptic Events?
Li, Y., Flood, P., & Cornes, S. (2015). Electroencephalography of Seizure-Like Movements During General Anesthesia with Propofol: Seizures or Nonepileptic Events? A & A Case Reports, 5(11), 195–98. -
Left Ventricular Ejection Fraction and Clinically Defined Heart Failure to Predict 90-Day Functional Outcome After Ischemic Stroke.
Li, Y., Fitzgibbons, T. P., McManus, D. D., Goddeau, R. P., Silver, B., & Henninger, N. (2018). Left Ventricular Ejection Fraction and Clinically Defined Heart Failure to Predict 90-Day Functional Outcome After Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. -
Potential use of leukocytosis and anion gap elevation in differentiating psychogenic nonepileptic seizures from epileptic seizures.
Li, Y., Matzka, L., Flahive, J., & Weber, D. (2019). Potential use of leukocytosis and anion gap elevation in differentiating psychogenic nonepileptic seizures from epileptic seizures. Epilepsia Open, 4(1), 210–15. -
Ephrin-b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine-induced model of epilepsy.
Liu, T.-T. T., Li, Y., Shu, Y., Xiao, B., & Feng, L. (2018). Ephrin-b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine-induced model of epilepsy. International Journal of Molecular Medicine, 41(6), 3457–3467. -
Epilepsy with temporal encephalocele: Characteristics of electrocorticography and surgical outcome.
Panov, F., Li, Y., Chang, E. F., Knowlton, R., & Cornes, S. B. (2016). Epilepsy with temporal encephalocele: Characteristics of electrocorticography and surgical outcome. Epilepsia, 57(2), e33–8. -
Anion gap can differentiate between psychogenic and epileptic seizures in the emergency setting.
Li, Y., Matzka, L., Maranda, L., & Weber, D. (2017). Anion gap can differentiate between psychogenic and epileptic seizures in the emergency setting. Epilepsia, 58(9), e132–e135. -
The Ephrin-A5/EphA4 Interaction Modulates Neurogenesis and Angiogenesis by the p-Akt and p-ERK Pathways in a Mouse Model of TLE.
Shu, Y., Xiao, B., Wu, Q., Liu, T., Du, Y., Tang, H., … Li, Y. (2016). The Ephrin-A5/EphA4 Interaction Modulates Neurogenesis and Angiogenesis by the p-Akt and p-ERK Pathways in a Mouse Model of TLE. Molecular Neurobiology, 53(1), 561–576. -
MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus.
Hu, K., Xie, Y.-Y. Y., Zhang, C., Ouyang, D.-S. S., Long, H.-Y. Y., Sun, D.-N. N., … Xiao, B. (2012). MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus. BMC Neuroscience, 13, 115. -
EphA4 may contribute to microvessel remodeling in the hippocampal CA1 and CA3 areas in a mouse model of temporal lobe epilepsy.
Feng, L., Shu, Y., Wu, Q., Liu, T., Long, H., Yang, H., … Xiao, B. (2017). EphA4 may contribute to microvessel remodeling in the hippocampal CA1 and CA3 areas in a mouse model of temporal lobe epilepsy. Molecular Medicine Reports, 15(1), 37–46. -
[Neuronal synaptic reconstruction in hippocampus in chronic phase of pilocarpine-treated rats].
Yi, F., Abuhamed, M. M., Long, L.-li L., Li, Y., Li, S.-yu Y., Wu, Z.-guo G., & Xiao, B. (2011). [Neuronal synaptic reconstruction in hippocampus in chronic phase of pilocarpine-treated rats]. Zhonghua Yi Xue Za Zhi, 91(19), 1335–9. -
Altered expression of pannexin proteins in patients with temporal lobe epilepsy.
Jiang, T., Long, H., Ma, Y., Long, L., Li, Y., Li, F., … Xiao, B. (2013). Altered expression of pannexin proteins in patients with temporal lobe epilepsy. Molecular Medicine Reports, 8(6), 1801–6. -
Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus.
Hu, K., Zhang, C., Long, L., Long, X., Feng, L., Li, Y., & Xiao, B. (2011). Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus. Neuroscience Letters, 488(3), 252–7. -
Selective loss and axonal sprouting of GABAergic interneurons in the sclerotic hippocampus induced by LiCl-pilocarpine.
Long, L., Xiao, B., Feng, L., Yi, F., Li, G., Li, S., … Li, Y. (2011). Selective loss and axonal sprouting of GABAergic interneurons in the sclerotic hippocampus induced by LiCl-pilocarpine. The International Journal of Neuroscience, 121(2), 69–85. -
Rapamycin suppresses the recurrent excitatory circuits of dentate gyrus in a mouse model of temporal lobe epilepsy.
Tang, H., Long, H., Zeng, C., Li, Y., Bi, F., Wang, J., … Xiao, B. (2012). Rapamycin suppresses the recurrent excitatory circuits of dentate gyrus in a mouse model of temporal lobe epilepsy. Biochemical and Biophysical Research Communications, 420(1), 199–204. -
DISC1 Regulates the Proliferation and Migration of Mouse Neural Stem/Progenitor Cells through Pax5, Sox2, Dll1 and Neurog2
Wu, Q., Tang, W., Luo, Z., Li, Y., Shu, Y., Yue, Z., … Feng, L. (2017). DISC1 Regulates the Proliferation and Migration of Mouse Neural Stem/Progenitor Cells through Pax5, Sox2, Dll1 and Neurog2. FRONTIERS IN CELLULAR NEUROSCIENCE, 11, 261. -
NDEL1 was decreased in the CA3 region but increased in the hippocampal blood vessel network during the spontaneous seizure period after pilocarpine-induced status epilepticus.
Wu, Q., Li, Y., Shu, Y., Feng, L., Zhou, L., Yue, Z. W., … Xiao, B. (2014). NDEL1 was decreased in the CA3 region but increased in the hippocampal blood vessel network during the spontaneous seizure period after pilocarpine-induced status epilepticus. Neuroscience, 268, 276–83. -
DISC1-related signaling pathways in adult neurogenesis of the hippocampus.
Wu, Q., Li, Y., & Xiao, B. (2013). DISC1-related signaling pathways in adult neurogenesis of the hippocampus. Gene, 518(2), 223–30. -
The increased expression of CD21 on AchR specified B cells in patients with myasthenia gravis
Yin, W., Allman, W., Ouyang, S., Li, Y., Li, J., Christadoss, P., & Yang, H. (2013). The increased expression of CD21 on AchR specified B cells in patients with myasthenia gravis. JOURNAL OF NEUROIMMUNOLOGY, 256(1-2), 49–54. -
Immature Dendritic Cell-Derived Exosomes: a Promise Subcellular Vaccine for Autoimmunity
Yin, W., Ouyang, S., Li, Y., Xiao, B., & Yang, H. (2013). Immature Dendritic Cell-Derived Exosomes: a Promise Subcellular Vaccine for Autoimmunity. INFLAMMATION, 36(1), 232–40. -
Ultrasound-guided lumbar puncture improves success rate and efficiency in overweight patients.
Li, Y., Carandang, R. A., Ade, S., Flahive, J., & Daniello, K. (2020). Ultrasound-guided lumbar puncture improves success rate and efficiency in overweight patients. Neurology. Clinical Practice, 10(4), 307–13. -
Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation.
Li, Y., Eliashiv, D., LaHue, S. C., Rao, V. R., Martini, M. L., Panov, F., … Meador, K. J. (2020). Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation. Epilepsy Research, 169, 106532. -
Antibody Prevalence in Epilepsy before Surgery (APES) in drug-resistant focal epilepsy.
Li, Y., Tymchuk, S., Barry, J., Muppidi, S., & Le, S. (2021). Antibody Prevalence in Epilepsy before Surgery (APES) in drug-resistant focal epilepsy. Epilepsia. -
Precision medicine in women with epilepsy: The challenge, systematic review, and future direction.
Li, Y., Zhang, S., Snyder, M. P., & Meador, K. J. (2021). Precision medicine in women with epilepsy: The challenge, systematic review, and future direction. Epilepsy & Behavior : E&B, 118, 107928. -
Impact of high-density EEG in presurgical evaluation for refractory epilepsy patients.
Li, Y., Fogarty, A., Razavi, B., Ardestani, P. M., Falco-Walter, J., Werbaneth, K., … Fisher, R. S. (2022). Impact of high-density EEG in presurgical evaluation for refractory epilepsy patients. Clinical Neurology and Neurosurgery, 219, 107336. -
Precision medicine in epilepsy.
McGinn, R. J., Von Stein, E. L., Summers Stromberg, J. E., & Li, Y. (2022). Precision medicine in epilepsy. Progress in Molecular Biology and Translational Science, 190(1), 147–188. -
How does foetal exposure to valproate produce adverse neurodevelopmental outcomes?
Meador, K. J., & Li, Y. (2022). How does foetal exposure to valproate produce adverse neurodevelopmental outcomes? Brain : a Journal of Neurology. -
Epilepsy and Pregnancy.
Li, Y., & Meador, K. J. (2022). Epilepsy and Pregnancy. Continuum (Minneapolis, Minn.), 28(1), 34–54.
Practice Locations
Comprehensive Epilepsy Program in Palo Alto Palo Alto, CA
Palo Alto, CA
Comprehensive Epilepsy Program in Palo Alto
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Important Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Patient Reviews
(50 reviews)
I felt I was taken care of
Dr. Li is excellent
Dr. Li was very friendly and knowledgeable. I felt good in her care. I felt confident about the decisions she was making for my health condition.
Doctor Yi Li is very patient and listens well.
She is very calm
Very easy to talk with
She’s attentive and professional.
Dr. Li is an excellent doctor. She pays attention to every detail & provides great recommendations & feedback. I am extremely happy to have her as my doctor🙠🠼
Dr Li is great because she takes the time to listen about my concerns. She is concise and clear with answers. Then tells what we will be looking/checking on the follow up. Some doctors just say we will do a follow up. But I don’t know why we are doing a follow up if I feel fine.
Very thorough, very pleasant.
Thank you Dr. Li. We really really enjoyed the video session because it saved us from driving to the Dr. This was just awesome even though we have done this 1st time.
She was excellent, very helpful! Glad to meet her!
Answered all questions. Have faith in Dr. Li
Dr Li is an excellent, caring healthcare professional.
Very good dr
Dr. Li, is very caring and took the time to make sure we understood what she was telling us.
The best
Excellent, comprehensive care. I’m very impressed.
She was very informative
She is so nice and helpful and very fast at answering any questions
The best yet
We think Dr. Li is great! She always makes us feel like she is attuned to our daughter's needs and listens to any concerns. She is very responsive.
She's attentive and compassionate.
She is a great Doctor and try’s to find alternatives to just taking medications or just prescribing them after I tell her how I react to them. I am also relieved that I can continue to see her.
Thank you to you and your care team..
Dr Li is listening to me very well and asked several questions about my situation. She gives me all the information I need and plans for the next steps.
She is a good doctor - right to the point but in a good way. No time is wasted but not rushed either.
Thank you for excellent care as always.
I believe very good doctor but there is a communication issue.
Dr. Li is always very attentive and we feel that our daughter is in good hands.
She is a caring doctor. Thank YOU!
My doctor was wonderful.
Dr. Li was very pleasant and helpful. She took the time to explain things and research any questions I had. I appreciated her willingness to help.
Dr. Li was thorough and patient and went above and beyond to include family members in the appointment, even those who could not be there in person. Felt like she truly cared and partnered in making the treatment plan, rather than just prescribing. Highly recommended
The doctor was very informative and had answers for me. She was very professional and I hardly see that in some doctors now.
she is knowledgeable, and explain my situation to us clearly.
Thank you
Excellent doctor
A very attentive and sympathetic doctor, quite possibly my favorite yet.
Dr. Li is very perceptive, listens well, and problem solves difficult issues. I really appreciate her!
Dr Li is very welcoming and able to listen to me during the visit. She is clear and concise in the discussion. She ensures that all the process and next steps are clear for me. She replied clearly to my questions. This video visit was helpful and satisfying for me.
Wonderful doctor, very knowledgeable and very caring. And she is definitely helping my situation.
We were very impressed! Everyone was calm and made us feel at ease. We also appreciate how thorough the doctors were. Their manner showed concern for our situation and also a confidence that they wanted to get to the bottom of our health concern.
She is very kind and helpful
She is good with customer service which is important for Doctors. She is really nice and takes time to explain.
Dr. Li is a good listener and has a kind and caring presence.
She is very helpful and available.
Very good reputayion
Yi Li was a great listener, very compassionate, kind, and thoughtful.
Excellent, very considerate, and clearly interested in my well-being and improving my situation based on her extensive knowledge and experience.
Dr. Li is terrific. Very thoughtful discussion of the issues. I appreciate her knowledge and attention.
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Referring Physicians
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