John W. MacArthur
Cardiothoracic surgeon, Cardiac surgeon
Assistant Professor of Cardiothoracic Surgery (Adult Cardiac Surgery) at the Stanford University Medical Center
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Professional Education
- Fellowship: Stanford University Thoracic Surgery Fellowship (2018) CA
- Board Certification: American Board of Thoracic Surgery, Thoracic Surgery (2019)
- Board Certification, Cardiothoracic Surgery, American Board of Thoracic Surgery (2019)
- Fellowship: Stanford University Dept of Cardiothoracic Surgery (2018) CA
- Board Certification: American Board of Surgery, General Surgery (2016)
- Residency: Hospital of University of Pennsylvania Surgery Residency (2016) PA
- Medical Education: Columbia University College of Physicians and Surgeons (2008) NY
Publications
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Preclinical evaluation of the engineered stem cell chemokine stromal cell-derived factor 1a analog in a translational ovine myocardial infarction model.
Macarthur, J. W., Cohen, J. E., McGarvey, J. R., Shudo, Y., Patel, J. B., Trubelja, A., … Woo, Y. J. (2014). Preclinical evaluation of the engineered stem cell chemokine stromal cell-derived factor 1a analog in a translational ovine myocardial infarction model. Circulation Research, 114(4), 650–59. -
Bioengineered Stromal Cell- Derived Factor-1 alpha Analogue Delivered as an Angiogenic Therapy Significantly Restores Viscoelastic Material Properties of Infarcted Cardiac Muscle
Trubelja, A., MacArthur, J. W., Sarver, J. J., Cohen, J. E., Hung, G., Shudo, Y., … Woo, Y. J. (2014). Bioengineered Stromal Cell- Derived Factor-1 alpha Analogue Delivered as an Angiogenic Therapy Significantly Restores Viscoelastic Material Properties of Infarcted Cardiac Muscle. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 136(8). -
A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy.
Cohen, J. E., Purcell, B. P., Macarthur, J. W., Mu, A., Shudo, Y., Patel, J. B., … Woo, Y. J. (2014). A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy. Circulation. Heart Failure, 7(4), 619–26. -
Tissue-engineered, hydrogel-based endothelial progenitor cell therapy robustly revascularizes ischemic myocardium and preserves ventricular function.
Atluri, P., Miller, J. S., Emery, R. J., Hung, G., Trubelja, A., Cohen, J. E., … Woo, Y. J. (2014). Tissue-engineered, hydrogel-based endothelial progenitor cell therapy robustly revascularizes ischemic myocardium and preserves ventricular function. Journal of Thoracic and Cardiovascular Surgery, 148(3), 1090–98. -
Combined heart and liver transplantation can be safely performed with excellent short- and long-term results.
Atluri, P., Gaffey, A., Howard, J., Phillips, E., Goldstone, A. B., Hornsby, N., … Woo, Y. J. (2014). Combined heart and liver transplantation can be safely performed with excellent short- and long-term results. Annals of Thoracic Surgery, 98(3), 858–62. -
Natural history of coexistent tricuspid regurgitation in patients with degenerative mitral valve disease: Implications for future guidelines
Goldstone, A. B., Howard, J. L., Cohen, J. E., MacArthur, J. W., Atluri, P., Kirkpatrick, J. N., & Woo, Y. J. (2014). Natural history of coexistent tricuspid regurgitation in patients with degenerative mitral valve disease: Implications for future guidelines. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 148(6), 2802–9. -
Shear-Thinning Supramolecular Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo
Rodell, C. B., MacArthur, J. W., Dorsey, S. M., Wade, R. J., Wang, L. L., Woo, Y. J., & Burdick, J. A. (2015). Shear-Thinning Supramolecular Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo. ADVANCED FUNCTIONAL MATERIALS, 25(4), 636–44. -
A "Repair-All" Strategy for Degenerative Mitral Valve Disease Safely Minimizes Unnecessary Replacement.
Goldstone, A. B., Cohen, J. E., Howard, J. L., Edwards, B. B., Acker, A. L., Hiesinger, W., … Woo, Y. J. (2015). A "Repair-All" Strategy for Degenerative Mitral Valve Disease Safely Minimizes Unnecessary Replacement. Annals of Thoracic Surgery, 99(6), 1983–90. -
Evaluation of late aortic insufficiency with continuous flow left ventricular assist device†.
Hiraoka, A., Cohen, J. E., Shudo, Y., Macarthur, J. W., Howard, J. L., Fairman, A. S., … Woo, Y. J. (2015). Evaluation of late aortic insufficiency with continuous flow left ventricular assist device†. European Journal of Cardio-Thoracic Surgery , 48(3), 400–406. -
A Tissue-Engineered Chondrocyte Cell Sheet Induces Extracellular Matrix Modification to Enhance Ventricular Biomechanics and Attenuate Myocardial Stiffness in Ischemic Cardiomyopathy
Shudo, Y., Cohen, J. E., MacArthur, J. W., Goldstone, A. B., Otsuru, S., Trubelja, A., … Woo, Y. J. (2015). A Tissue-Engineered Chondrocyte Cell Sheet Induces Extracellular Matrix Modification to Enhance Ventricular Biomechanics and Attenuate Myocardial Stiffness in Ischemic Cardiomyopathy. TISSUE ENGINEERING PART A, 21(19-20), 2515–25. -
A "Repair-All" Strategy for Degenerative Mitral Valve Disease Safely Minimizes Unnecessary Replacement
Goldstone, A. B., Cohen, J. E., Howard, J. L., Edwards, B. B., Acker, A. L., Hiesinger, W., … Woo, Y. J. (2015). A "Repair-All" Strategy for Degenerative Mitral Valve Disease Safely Minimizes Unnecessary Replacement. ANNALS OF THORACIC SURGERY, 99(6), 1983–91. -
Isolation and trans-differentiation of mesenchymal stromal cells into smooth muscle cells: Utility and applicability for cell-sheet engineering.
Shudo, Y., Cohen, J. E., Goldstone, A. B., MacArthur, J. W., Patel, J., Edwards, B. B., … Woo, Y. J. (2016). Isolation and trans-differentiation of mesenchymal stromal cells into smooth muscle cells: Utility and applicability for cell-sheet engineering. Cytotherapy, 18(4), 510–17. -
Biochemically engineered stromal cell-derived factor 1-alpha analog increases perfusion in the ischemic hind limb.
Edwards, B. B., Fairman, A. S., Cohen, J. E., Macarthur, J. W., Goldstone, A. B., Woo, J. B., … Woo, Y. J. (2016). Biochemically engineered stromal cell-derived factor 1-alpha analog increases perfusion in the ischemic hind limb. Journal of Vascular Surgery, 64(4), 1093–99. -
Injectable Bioengineered Hydrogel Therapy in the Treatment of Ischemic Cardiomyopathy.
MacArthur, J. W., Steele, A. N., Goldstone, A. B., Cohen, J. E., Hiesinger, W., & Woo, Y. J. (2017). Injectable Bioengineered Hydrogel Therapy in the Treatment of Ischemic Cardiomyopathy. Current Treatment Options in Cardiovascular Medicine, 19(4), 30-? -
An innovative biologic system for photon-powered myocardium in the ischemic heart.
Cohen, J. E., Goldstone, A. B., Paulsen, M. J., Shudo, Y., Steele, A. N., Edwards, B. B., … Woo, Y. J. (2017). An innovative biologic system for photon-powered myocardium in the ischemic heart. Science Advances, 3(6), e1603078. -
Non-resectional leaflet remodeling mitral valve repair preserves leaflet mobility: A quantitative echocardiographic analysis of mitral valve configuration
Shudo, Y., Cohen, J. E., MacArthur, J. W., Goldstone, A. B., Hiraoka, A., Howard, J., … Woo, Y. J. (2015). Non-resectional leaflet remodeling mitral valve repair preserves leaflet mobility: A quantitative echocardiographic analysis of mitral valve configuration. INTERNATIONAL JOURNAL OF CARDIOLOGY, 186, 16–18. -
SDF 1-alpha Attenuates Myocardial Injury Without Altering the Direct Contribution of Circulating Cells.
Goldstone, A. B., Burnett, C. E., Cohen, J. E., Paulsen, M. J., Eskandari, A., Edwards, B. E., … Woo, Y. J. (2018). SDF 1-alpha Attenuates Myocardial Injury Without Altering the Direct Contribution of Circulating Cells. Journal of Cardiovascular Translational Research. -
The tip of the iceberg: Evaluating the mechanism behind dehiscence of mitral annuloplasty rings.
MacArthur, J. W., & Boyd, J. (2017). The tip of the iceberg: Evaluating the mechanism behind dehiscence of mitral annuloplasty rings. The Journal of Thoracic and Cardiovascular Surgery. -
Cell transplantation in heart failure: where do we stand in 2016?
MacArthur, J. W., Goldstone, A. B., Cohen, J. E., Hiesinger, W., & Woo, Y. J. (2016). Cell transplantation in heart failure: where do we stand in 2016? EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 50(3), 396–99. -
Stem Cell Therapy: Healing or Hype? Why Stem Cell Delivery Doesn't Work
Steele, A. N., MacArthur, J. W., & Woo, Y. J. (2017). Stem Cell Therapy: Healing or Hype? Why Stem Cell Delivery Doesn't Work. CIRCULATION RESEARCH, 120(12), 1868–70. -
Shear-Thinning Supramolecular Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo.
Rodell, C. B., MacArthur, J. W., Dorsey, S. M., Wade, R. J., Wang, L. L., Woo, Y. J., & Burdick, J. A. (2015). Shear-Thinning Supramolecular Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo. Advanced Functional Materials, 25(4), 636–44. -
Bioengineered analog of stromal cell-derived factor 1a preserves the biaxial mechanical properties of native myocardium after infarction.
Wang, H., Wisneski, A., Paulsen, M. J., Imbrie-Moore, A., Wang, Z., Xuan, Y., … Woo, Y. J. (2019). Bioengineered analog of stromal cell-derived factor 1a preserves the biaxial mechanical properties of native myocardium after infarction. Journal of the Mechanical Behavior of Biomedical Materials, 96, 165–71.
Practice Locations
Heart Transplant Program Stanford, CA
Stanford, CA
Heart Transplant Program
300 Pasteur Drive , 2nd Floor, Room A21
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Aortic Disease Center Stanford, CA
Stanford, CA
Aortic Disease Center
300 Pasteur Drive, 3rd Floor, Clinic A31
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Valvular Heart Disease Clinic Stanford, CA
Stanford, CA
Valvular Heart Disease Clinic
300 Pasteur Drive, 3rd Floor, Clinic A31
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Referring Physicians
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