Mark Pegram, MD

Mark Pegram, MD

Medical oncologist, Breast specialist

Bio:   Mark D. Pegram, MD, is the first director of the Breast Cancer Oncology Program at Stanford Women’s Cancer Center. He is also the co-director of Stanford’s Molecular Therapeutics Program. He is a renowned clinician and scholar in breast cancer research and a leader in translational medicine. Dr. Pegram played a major role in developing the drug Herceptin as a treatment for HER2-positive breast cancer, which constitutes about 20 percent of all cases. His laboratory experiments demonstrated that combining Herceptin with chemotherapy effectively killed cancer cells that overproduced the growth factor HER2. Dr. Pegram and others then conducted clinical trials showing that Herceptin improved survival rates and even cured some breast cancer patients. This remains one of the premier examples of bench-to-bedside translational research. Dr. Pegram’s current research efforts include a continued focus on the cancer-associated gene that encodes HER2 and developing new ways to target cancer cells expressing this protein. He is also pursuing strategies to target estrogen receptors, implicated in some 70 percent of all breast cancer cases.
Dr. Pegram earned his undergraduate and medical degrees from the University of North Carolina before joining the faculty of the University of California, Los Angeles. He spent five years at the University of Miami Miller School of Medicine, where he was a Sylvester Chair professor of medicine in the Braman Family Breast Cancer Institute and associate director for clinical research in the University’s Sylvester Comprehensive Cancer Center. He joined the Stanford faculty in 2012.
4.8 out of 5
124 Patient Ratings
24 Patient Comments

Breast Cancer Program in Palo Alto

  • 900 Blake Wilbur Drive
  • 1st Floor
  • Palo Alto, CA 94304
  • Phone: 650-498-6004
More Clinic Information » Insurance Coverage » Getting Here » Make An Appointment

Stanford Women's Cancer Center

  • 900 Blake Wilbur Drive
  • 1st Floor
  • Palo Alto, CA 94304
  • Phone: 650-498-6004
More Clinic Information » Insurance Coverage » Getting Here » Make An Appointment

Cancer Immunotherapy Program

Professional Education

  • Board Certification: Medical Oncology, American Board of Internal Medicine (1993)
  • Board Certification: Internal Medicine, American Board of Internal Medicine (1989)
  • Internship: Univ Of Texas Southwestern (1987) TX
  • Residency: Univ Of Texas Southwestern (1987) TX
  • Fellowship: UCLA - School of Medicine (1993) CA
  • Medical Education: University of North Carolina (1986) NC

Honors & Awards

  • Sylvester Outstanding Cancer Research Award, University of Miami Sylvester Comprehensive Cancer Center (13 May 2011)
  • 6th Annual Connie Moskow Memorial Lectureship, Robert H. Lurie Comprehensive Cancer Center of Northwestern University (11 May 2012)
  • John G. Kuhn Lecture, Hematology/Oncology Pharmacy Association (21 March 2013)
  • Chair, Department of Defense Breast Cancer Research Program Integration Panel, Congressionally Directed Medical Research Programs, U.S. Army Research and Materiel Command (2012)
  • 2012 Keynote Lecture, American Radium Society 94th Annual Meeting, American Radium Society (29 April 2012)
  • The Celebrity Cruises Award, The Breast Cancer Research Foundation (2013-2014)

Administrative Appointments

  • Associate Director for Clinical Research, Stanford Cancer Institute (2013 - Present)
  • Director, Stanford Breast Oncology Program, Stanford Cancer Institute (2012 - Present)
  • Co-Director, Translational Oncology Research Program @ Stanford (TOP@S), Stanford Cancer Institute (2013 - Present)
4.8

Friendliness

4.8

Recommended to others

4.8

Explanations

4.8

Listens

4.8

Includes you in decisions

4.9

Clear Communication

4.8

Confidence in your doctor

3.7

Wait times

SHC Patient, Jul 2016

Dr. Pegram is outstanding, he is busy but made sure that he is with you 100% when I am with him for consultation. He listen & has answers.

SHC Patient, May 2016

My experience with Mark Pegram and his staff has been excellent.

SHC Patient, Apr 2016

Dr. Pegram is a wonderful doctor. So kind and caring. He is held in high regard by my entire team in Ann Arbor, Michigan.

SHC Patient, Apr 2016

Dr. Pegram is awesome. Yes I would highly recommend him.

SHC Patient, Mar 2016

Very professional.

SHC Patient, Feb 2016

Dr. Paul & Dr. Pegram were wonderful. I made my surgery decision based on what Dr. Pegram said. He inspired confidence.

SHC Patient, Jan 2016

Dr. Pegram is thorough in his analysis & approach and candid in his explanations. He shows compassion & concern and provides alternatives for treatment.

SHC Patient, Nov 2015

A fine person and always helpful. The BEST!!

SHC Patient, Nov 2015

NOT NP. Dr. Pegram is a very good listener and comes across as caring and invested in my recovery. Same w/Emily Storey - I feel like I am n good hands.

SHC Patient, Sep 2015

Dr. Pegram is absolutely AMAZING!! He made me feel at ease and I was thoroughly happy with his guidance. Stanford is blessed to have such an accomplished dr.

SHC Patient, Jul 2015

Dr. Pegram is the best doctor I have ever had. He is thorough, kind and just nice.

SHC Patient, Jul 2015

The oncologist is great and very knowledgeable in his field. I feel there are so many patients though and the care is not as personable and there's no one-on-one. I usually need to follow up with blood orders & test results and explanations of the results.

View All 24 Patient Comments »
4.8 out of 5
124 Patient Ratings
24 Patient Comments

SHC Patient, Jul 2016

Dr. Pegram is outstanding, he is busy but made sure that he is with you 100% when I am with him for consultation. He listen & has answers.

SHC Patient, May 2016

My experience with Mark Pegram and his staff has been excellent.

SHC Patient, Apr 2016

Dr. Pegram is a wonderful doctor. So kind and caring. He is held in high regard by my entire team in Ann Arbor, Michigan.

SHC Patient, Apr 2016

Dr. Pegram is awesome. Yes I would highly recommend him.

SHC Patient, Mar 2016

Very professional.

SHC Patient, Feb 2016

Dr. Paul & Dr. Pegram were wonderful. I made my surgery decision based on what Dr. Pegram said. He inspired confidence.

SHC Patient, Jan 2016

Dr. Pegram is thorough in his analysis & approach and candid in his explanations. He shows compassion & concern and provides alternatives for treatment.

SHC Patient, Nov 2015

A fine person and always helpful. The BEST!!

SHC Patient, Nov 2015

NOT NP. Dr. Pegram is a very good listener and comes across as caring and invested in my recovery. Same w/Emily Storey - I feel like I am n good hands.

SHC Patient, Sep 2015

Dr. Pegram is absolutely AMAZING!! He made me feel at ease and I was thoroughly happy with his guidance. Stanford is blessed to have such an accomplished dr.

SHC Patient, Jul 2015

Dr. Pegram is the best doctor I have ever had. He is thorough, kind and just nice.

SHC Patient, Jul 2015

The oncologist is great and very knowledgeable in his field. I feel there are so many patients though and the care is not as personable and there's no one-on-one. I usually need to follow up with blood orders & test results and explanations of the results.

SHC Patient, Jul 2015

The breast cancer oncology team is wonderful caring skilled - an excellent experience in spite of the cancer.

SHC Patient, Jul 2015

Exceptional for ALL care givers.

SHC Patient, Jul 2015

Bernie is amazing, friendly, helpful.

SHC Patient, May 2015

Just terrific care.

SHC Patient, May 2015

Love Dr. Pegram. Would recommend him but would make sure referral understands he is NEVER timely.

SHC Patient, May 2015

Dr. Pegram made the final decision about my care.

SHC Patient, Apr 2015

Dr. Pegram saved my life. He recognized a pending heart problem - sent me to emergency where I had a cardiac arrest! He was on the ball 100%

SHC Patient, Apr 2015

Dr. Pegram is very knowledgeable, kind and compassionate. He has given me the confidence to continue to fight my cancer.

SHC Patient, Feb 2015

Didn't have time to answer questions in some cases answered a related question, not the one I asked.

SHC Patient, Nov 2014

Dr. Pegram rocks! He is caring. Very knowledgeable, inspires confidence, astute.

SHC Patient, Aug 2014

Anything negative is far overshadowed by all the GOOD received from Dr. Pegram!!

SHC Patient, May 2014

I come all the way from Petaluma because I feel that I have a better chance of living longer because of Stanford providers.