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Radionuclide Angiography for Atherosclerosis

  • About
  • About
Overview
Symptoms
Causes
Diagnosis
  • Coronary arteriogram (or angiogram)
  • Doppler sonography
  • MUGA/radionuclide angiography
Treatments
  • Coronary angioplasty
  • Coronary artery bypass graft surgery
Overview
Symptoms
Causes
Diagnosis
  • Coronary arteriogram (or angiogram)
  • Doppler sonography
  • MUGA/radionuclide angiography
Treatments
  • Coronary angioplasty
  • Coronary artery bypass graft surgery

What Is a Resting and Exercise Radionuclide Angiogram (RNA)?

Resting and exercise radionuclide angiogram (RNA) is a type of nuclear medicine procedure. This means that a tiny amount of a radioactive substance, called a radionuclide (radiopharmaceutical or radioactive tracer), is used during the procedure to assist in the examination of the tissue under study. Specifically, resting RNA evaluates the heart's chambers in motion.

MUGA/radionuclide angiography uses radioactive imaging to view blood flow, internal organ structure, and organ function, including how the heart wall moves and how much blood is expelled with each heartbeat, while the patient is at rest.

A radionuclide (usually technetium) will be injected into an arm vein to "tag" the blood cells so their progress through the heart can be traced with a scanner.

A special camera (gamma camera) will make recordings of the heart wall at work, like a motion picture. These recordings will be synchronized with the heartbeat by using the electrocardiogram (ECG, or recording of the heart's electrical activity).

A cardiologist (a physician who specializes in heart disease) trained in nuclear cardiology will study the films to evaluate the heart's pumping function and ejection fraction (the volume of blood pumped out with each heartbeat).

An RNA procedure with rest and exercise is performed to assist the physician in assessing the heart's function during exercise after comparing it to the heart's function at rest.

If the heart muscle does not move in a normal manner, and/or a less-than-normal amount of blood is pumped out by the heart, this may indicate one or more of the following:

  • Injury to the heart muscle, possibly as a result of decreased blood flow to heart muscle due to clogged coronary arteries
  • An enlargement of one or more of the heart's chambers
  • Aneurysm (a weak spot in the heart muscle)
  • Toxic effects of certain medications

Related procedures

Other related procedures that may be used to assess the heart include:

  • Resting or exercise electrocardiogram (ECG or EKG)
  • Holter monitor
  • Signal-averaged ECG
  • Cardiac catheterization
  • Chest X-ray
  • Computed tomography (CT scan) of the chest
  • Echocardiogram
  • Electrophysiological studies
  • Magnetic resonance imaging (MRI) of the heart
  • Myocardial perfusion scans
  • Ultrafast CT scan
Previous Section Next Section

Heart Disease is Preventable.

  • Learn How to Reduce Your Risk with Food for Heart »

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Open Trials Closed Trials
Systolic Pressure Intervention Trial Factors Affecting Factors Affecting Atherosclerosis Study Atherosclerosis, Chronic Hypertension, Resistant Hypertension
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.) Atherosclerosis
Personal Genomics for Preventive Cardiology Coronary Artery Disease, Non-obstructive Coronary Artery Disease, Obstructive Coronary Artery Disease
Investigation of The Effect of Cenicriviroc (CVC) Plus FTC/TDF on Cardiovascular Disease Risk Factors Atherosclerosis, Heart Disease, HIV and AIDS
Protected Carotid Artery Stenting in Subjects at High Risk for Carotid Endarterectomy (CEA) (PROTECT) Aortic Stenosis, Atherosclerosis, Carotid Artery Disease/Carotid Artery Stenosis

Clinics for MUGA/radionuclide angiography

  • Vascular and Endovascular Care
    650-725-5227
  • Interventional Neuroradiology Program
    650-723-6469
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