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Some congenital heart defects allow blood to flow between the right and left chambers of the heart because an infant is born with an opening in the septal wall that separates the right and left sides of the heart.
Because of this opening, blood from the left ventricle flows back into the right ventricle, due to higher pressure in the left ventricle. This causes an extra volume of blood to be pumped into the lungs by the right ventricle, which can create congestion in the lungs.
Open trials refer to studies currently recruiting participants or that may recruit participants in the near future. Closed trials are not currently enrolling, but similar studies may open in the future.
Closed trials are not currently enrolling, but may open in the future.