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Scleroderma, also called systemic sclerosis, is a chronic, degenerative disease that affects the joints, skin and internal organs. Scleroderma is also associated with blood vessel abnormalities.
Scleroderma: Multifactorial Condition
Scleroderma is considered to be a multifactorial condition, meaning that many factors are involved in causing the problem. The factors are usually both genetic and environmental: a combination of genes from both parents, in addition to unknown environmental factors, produce the condition.
In multifactorial conditions, one gender is usually affected more frequently. Scleroderma affects females three to four times more often than it affects males.
Symptoms of scleroderma include thickening and swelling of the fingertips and joint pain. Learn more about scleroderma symptoms.
CREST syndrome is a less severe form of scleroderma. Learn more about CREST syndrome.
We look for changes in your skin and internal organs in order to diagnose scleroderma. Learn more about scleroderma diagnosis.