Dr. Clarke is a preventive cardiologist and a physician-scientist focused on disease prevention. He earned his undergraduate degree in human biology from the Division of Nutritional Sciences at Cornell University before obtaining his MD and PhD (genetics) from Stanford University School of Medicine. He has completed clinical training in internal medicine (Brigham & Women’s Hospital), pediatrics (Boston Children’s Hospital), and cardiovascular medicine (Stanford Hospital), and he is board certified in all three specialties. His research is focused on 1) understanding complex disease genetics in diverse populations, 2) integrating monogenic and polygenic risk with clinical risk, 3) large-scale phenotyping using the electronic health record and medical images. His clinical practice focuses on identifying risk factors for cardiovascular disease with the goal of promoting health and longevity through evidence-based personalized treatment. He is interested in developing family-centric approaches for the treatment of adults and children carrying genetic risk for disease.

Professional Summary

Education & Certifications
  • Board certified, American Board of Internal Medicine, Cardiovascular Disease
  • Board certified, American Board of Pediatrics, Pediatrics
  • Board certified, American Board of Internal Medicine, Internal Medicine
  • Fellow, Stanford University School of Medicine, Cardiovascular Medicine (2020)
  • Resident, Brigham & Women's Hospital and Boston Children's Hospital, Internal Medicine and Pediatrics (2017)
  • PhD, Stanford University School of Medicine, Genetics (2013)
  • MD, Stanford University School of Medicine (2013)

Honors & Awards
  • Chair Diversity Investigator Award, Stanford University Department of Medicine (2021)
  • Chief Fellow, Stanford Division of Cardiovascular Medicine (2019)
  • Gilliam Fellow, Howard Hughes Medical Institute (2008 - 2013)
  • House Officer Research Award, Boston Children's Hospital (2016)
  • Resource Centers for Minority Aging Research (RCMAR) Scientist, National Institute on Aging (2022)


Practice Locations

Preventive Cardiology Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 725-5909

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Patient Ratings

(10 Ratings)

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The Patients Ratings and comments are gathered from our Patient Satisfaction Survey and displayed in their entirety.

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Patient Reviews

(28 reviews)

I feel heard & I appreciate the time spent to explain condition, meditations, etc
Dr Lee Clarke is the best! Thank you for your help and knowledge
He is awesome! So knowledgeable and personable. He takes the time to listen to me and explains things that are easy to understand and helpful.
I every confidence in Dr. Clarke as my physician! He's knowledgeable, happy to answer my questions, explain and help me understand my condition, care option's and why. Does not hurry you off, he takes time to understand.
Thank you Dr Lee. I feel safer when a doctor like you talks about patient’s (me) concerns not making me feel the need to hurry and end the conversation, and you explained everything for me to understand things about my concerns.
Dr. Clarke did an exceptional job in explaining my lab results and answering all my questions. He is very genuine and caring person that helps create an atmosphere of trust and support during the visit.
Dr Clarke talked slowly and clearly which ensured that everything was effectively communicated. As a scientist, it did feel a little slow to me, but I understand that it is more important to be clear.
Lee Clarke is an excellent physician.
Dr Clarke is excellent, takes care to listen and explain. He is very knowledgeable!
Good communicator. Patient. Listens.
He is a fine doctor. I like working with him.😊
He is very easy to talk to and a very good listener.
He is wonderful and really set me in the right direction. it is hard to find a doctor that really cares, i believe he does!
Dr. Clarke is very thorough and knowledgeable; he explained all the tests and procedures in simple terms.
We discussed the questions that I had and I got the information I was hoping to get. It was great.
I had a very good and informative meeting
Dr.Clarke is a caring professional.
Thank you I appreciate you taking the time to explain thanks!
Really glad and fortunate to have Dr. Clarke as my doctor. He is friendly, knowledgeable, and great. Thank you.
Dr. Lee is great.He address all my concerns.
Excellent doctor. Knowledgeable, good listener, empathetic, responsive....first-rate, a real keeper.
Dr Lee Clarke is very thorough. He is also kind, calm and pays close attention to what I’m saying and asking. He listens carefully and allows me to express my thoughts, even if they are jumbled. He is present in our conversation, gracefully addresses my concerns and thoughtfully answers my questions. He is extremely knowledgeable and maps out a plan for me. All of these traits make me feel confident under his care. Thank you Dr Clarke.
Good bedside manners. Respectful. Knowledgeable. Good explanations. Likeable.
Grateful Dr Clarke allowed time for and addressed questions. Appreciated to offer information and studies to be sent to me to read for additional education.
He is an excellent and caring physician. I am grateful to be under his care.
Excellent provider
Dr. Clarke explained everything I needed to know and we have a plan
Dr Clarke is such a wonderful doctor, he is thoughtful & kind & knowledgeable about the medicine he practices .

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