Biography
Professional Summary
Education & Certifications
- Fellowship: Stanford University Hematology and Oncology Fellowship (1971) CA
- Residency: Stanford University Internal Medicine Residency (1968) CA
- Residency: Barnes and Allied Hospitals/Washington University School of Med (1965) MO
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- Internship: Barnes and Allied Hospitals/Washington University School of Med (1964) MO
- Medical Education: George Washington University School of Medicine and Health Sciences (1963) DC
- Board Certification: American Board of Internal Medicine, Hematology (1976)
- Board Certification: American Board of Internal Medicine, Internal Medicine (1970)
- B.A., Johns Hopkins University, Biological Sciences (1959)
- M.D., George Washington U Med School, Medicine (1963)
Honors & Awards
- International Prize for outstanding research in myelodysplastic syndromes (MDS), J.P. McCarthy Foundation (1997)
- Lifetime Achievement Award for MDS, International Workshop for MDS (2022)
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Memberships
- Member, American Society of Hematology (1972 - Present)
- Member, Eastern Cooperative Oncology Group, Leukemia Committee (1993 - 2018)
- Chairman, NCCN Myelodysplastic Syndrome Guidelines Panel (1997 - Present)
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- Coordinator, International Working Group for Prognosis in MDS (IWG-PM) (2009 - Present)
- Executive Committee, MDS Foundation, Inc (2009 - Present)
- Member, World Health Organization Clinical Advisory Committee for Myeloid Malignancies (2014 - Present)
Administrative Appointments
- Acting Chief, Medical Service, VA Palo Alto Health Care System (1978 - 1979)
- Chair, National Comprehensive Cancer Network Myelodysplastic Syndromes Practice Guidelines Panel (1997 - 2023)
- Coordinator, International Working Group for Prognosis in MDS (2009 - 2023)
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- Director, Stanford MDS Center (1998 - 2023)
- Head, Hematology Section, VA Palo Alto Health Care System (1979 - 2005)
- Member, Stanford Scientific Review Committee (2009 - 2023)
Publications
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Prognostic scoring systems for risk assessment in myelodysplastic syndromes.
Greenberg, P. L., Sanz, G. F., & Sanz, M. A. (1999). Prognostic scoring systems for risk assessment in myelodysplastic syndromes. Forum (Genoa, Italy), 9(1), 17–31. -
Implications of pathogenetic and prognostic features for management of myelodysplastic syndromes
Greenberg, P. (2001). Implications of pathogenetic and prognostic features for management of myelodysplastic syndromes. LANCET, 357(9262), 1059–60. -
Treatment of myelodysplastic syndrome with agents interfering with inhibitory cytokines
Greenberg, P. (2001). Treatment of myelodysplastic syndrome with agents interfering with inhibitory cytokines. ANNALS OF THE RHEUMATIC DISEASES, 60, III41–III42. -
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Myelodysplastic syndromes.
Greenberg, P. L., Young, N. S., & Gattermann, N. (2002). Myelodysplastic syndromes. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 136–61. -
Comparison of interphase FISH and metaphase cytogenetics to study myelodysplastic syndrome: an Eastern Cooperative Oncology Group (ECOG) study
Cherry, A. M., Brockman, S. R., Paternoster, S. F., Hicks, G. A., Neuberg, D., Higgins, R. R., … DeWald, G. W. (2003). Comparison of interphase FISH and metaphase cytogenetics to study myelodysplastic syndrome: an Eastern Cooperative Oncology Group (ECOG) study. LEUKEMIA RESEARCH, 27(12), 1085–90. -
TREATMENT OF MYELODYSPLASTIC SYNDROMES WITH HEMATOPOIETIC GROWTH-FACTORS
Greenberg, P. L. (1992). TREATMENT OF MYELODYSPLASTIC SYNDROMES WITH HEMATOPOIETIC GROWTH-FACTORS. SEMINARS IN ONCOLOGY, 19(1), 106–14. -
T-CELL SUBSETS AND SUPPRESSOR CELLS IN HUMAN BONE-MARROW
SCHMIDTWOLF, I. G. H., DEJBAKHSHJONES, S., Ginzton, N., Greenberg, P., & Strober, S. (1992). T-CELL SUBSETS AND SUPPRESSOR CELLS IN HUMAN BONE-MARROW. BLOOD, 80(12), 3242–50. -
Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: A phase III trial (E2995)
Greenberg, P. L., Lee, S. J., Advani, R., Tallman, M. S., Sikic, B. I., Letendre, L., … Rowe, J. M. (2004). Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: A phase III trial (E2995). JOURNAL OF CLINICAL ONCOLOGY, 22(6), 1078–86. -
Management of patients with higher risk myelodysplastic syndromes
Fukumoto, J. S., & Greenberg, P. L. (2005). Management of patients with higher risk myelodysplastic syndromes. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 56(2), 179–92. -
Myelodysplastic syndromes clinical practice guidelines in oncology.
Greenberg, P. L., Baer, M. R., Bennett, J. M., Bloomfield, C. D., De Castro, C. M., Deeg, H. J., … Tallman, M. S. (2006). Myelodysplastic syndromes clinical practice guidelines in oncology. Journal of the National Comprehensive Cancer Network , 4(1), 58–77. -
Myelodysplastic syndromes: iron overload consequences and current chelating therapies.
Greenberg, P. L. (2006). Myelodysplastic syndromes: iron overload consequences and current chelating therapies. Journal of the National Comprehensive Cancer Network , 4(1), 91–96. -
HEMATOPOIETIC PROGENITOR-CELL EXPRESSION OF THE H-CAM (CD44) HOMING-ASSOCIATED ADHESION MOLECULE
LEWINSOHN, D. M., Nagler, A., Ginzton, N., Greenberg, P., & BUTCHER, E. C. (1990). HEMATOPOIETIC PROGENITOR-CELL EXPRESSION OF THE H-CAM (CD44) HOMING-ASSOCIATED ADHESION MOLECULE. BLOOD, 75(3), 589–95. -
EFFECTS OF RECOMBINANT HUMAN GRANULOCYTE COLONY STIMULATING FACTOR AND GRANULOCYTE-MONOCYTE COLONY STIMULATING FACTOR ON INVITRO HEMATOPOIESIS IN THE MYELODYSPLASTIC SYNDROMES
Nagler, A., Ginzton, N., Negrin, R., Bang, D., Donlon, T., & Greenberg, P. (1990). EFFECTS OF RECOMBINANT HUMAN GRANULOCYTE COLONY STIMULATING FACTOR AND GRANULOCYTE-MONOCYTE COLONY STIMULATING FACTOR ON INVITRO HEMATOPOIESIS IN THE MYELODYSPLASTIC SYNDROMES. LEUKEMIA, 4(3), 193–202. -
EFFECTS OF PROLONGED TREATMENT OF MYELODYSPLASTIC SYNDROMES WITH RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR
Greenberg, P., Negrin, R., Nagler, A., Vincent, M., & Donlon, T. (1990). EFFECTS OF PROLONGED TREATMENT OF MYELODYSPLASTIC SYNDROMES WITH RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR. Presented at the 2ND INTERNATIONAL CONF ON BLOOD CELL GROWTH FACTORS : THEIR BIOLOGY AND CLINICAL APPLICATIONS, CAPRI,ITALY,ITALY,ITALY: ALPHAMED PRESS. -
MAINTENANCE TREATMENT OF PATIENTS WITH MYELODYSPLASTIC SYNDROMES USING RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR
Negrin, R. S., HAEUBER, D. H., Nagler, A., Kobayashi, Y., Sklar, J., Donlon, T., … Greenberg, P. L. (1990). MAINTENANCE TREATMENT OF PATIENTS WITH MYELODYSPLASTIC SYNDROMES USING RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR. BLOOD, 76(1), 36–43. -
EFFECTS OF CSFS IN PRELEUKEMIA
Greenberg, P. L., Negrin, R., & Nagler, A. (1990). EFFECTS OF CSFS IN PRELEUKEMIA. Presented at the 3RD INTERNATIONAL SYMP ON MINIMAL RESIDUAL DISEASE IN ACUTE LEUKEMIA, ROTTERDAM,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS,NETHERLANDS: STOCKTON PRESS. -
IMPACT OF MARROW CYTOGENETICS AND MORPHOLOGY ON INVITRO HEMATOPOIESIS IN THE MYELODYSPLASTIC SYNDROMES - COMPARISON BETWEEN RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR (CSF) AND GRANULOCYTE-MONOCYTE CSF
Nagler, A., Binet, C., MacKichan, M. L., Negrin, R., Bangs, C., Donlon, T., & Greenberg, P. (1990). IMPACT OF MARROW CYTOGENETICS AND MORPHOLOGY ON INVITRO HEMATOPOIESIS IN THE MYELODYSPLASTIC SYNDROMES - COMPARISON BETWEEN RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR (CSF) AND GRANULOCYTE-MONOCYTE CSF. BLOOD, 76(7), 1299–1307. -
FUNCTIONAL INTERACTIONS BETWEEN COLONY-STIMULATING FACTORS AND THE INSULIN FAMILY HORMONES FOR HUMAN MYELOID LEUKEMIC-CELLS
Oksenberg, D., DIECKMANN, B. S., & Greenberg, P. L. (1990). FUNCTIONAL INTERACTIONS BETWEEN COLONY-STIMULATING FACTORS AND THE INSULIN FAMILY HORMONES FOR HUMAN MYELOID LEUKEMIC-CELLS. CANCER RESEARCH, 50(20), 6471–77. -
TREATMENT OF MYELODYSPLASTIC SYNDROMES
Greenberg, P. L. (1991). TREATMENT OF MYELODYSPLASTIC SYNDROMES. BLOOD REVIEWS, 5(1), 42–50. -
INVITRO MARROW CULTURE STUDIES IN THE MYELODYSPLASTIC SYNDROMES
Greenberg, P. L. (1992). INVITRO MARROW CULTURE STUDIES IN THE MYELODYSPLASTIC SYNDROMES. SEMINARS IN ONCOLOGY, 19(1), 34–46. -
Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study
Porter, J., Galanello, R., Saglio, G., Neufeld, E. J., Vichinsky, E., Cappellini, M. D., … Rose, C. (2008). Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study. EUROPEAN JOURNAL OF HAEMATOLOGY, 80(2), 168–76. -
Myelodysplastic syndromes.
Greenberg, P. L., Attar, E., Battiwalla, M., Bennett, J. M., Bloomfield, C. D., DeCastro, C. M., … Westervelt, P. (2008). Myelodysplastic syndromes. Journal of the National Comprehensive Cancer Network , 6(9), 902–26. -
The costs of drugs used to treat myelodysplastic syndromes following National Comprehensive Cancer Network Guidelines.
Greenberg, P. L., Cosler, L. E., Ferro, S. A., & Lyman, G. H. (2008). The costs of drugs used to treat myelodysplastic syndromes following National Comprehensive Cancer Network Guidelines. Journal of the National Comprehensive Cancer Network , 6(9), 942–53. -
A phase II intra-patient dose-escalation trial of weight-based darbepoetin alfa with or without granulocyte-colony stimulating factor in myelodysplastic syndromes
Gotlib, J., Lavori, P., Quesada, S., Stein, R. S., Shahnia, S., & Greenberg, P. L. (2009). A phase II intra-patient dose-escalation trial of weight-based darbepoetin alfa with or without granulocyte-colony stimulating factor in myelodysplastic syndromes. AMERICAN JOURNAL OF HEMATOLOGY, 84(1), 15–20. -
EFFECTS OF INSULIN-LIKE GROWTH-FACTORS ON HEMATOPOIESIS
Greenberg, P. L. (1991). EFFECTS OF INSULIN-LIKE GROWTH-FACTORS ON HEMATOPOIESIS. BLOOD CELLS, 17(2), 344–46. -
Treatment of myelodysplastic syndrome patients with erythropoietin with or without granulocyte colony-stimulating factor: results of a prospective randomized phase 3 trial by the Eastern Cooperative Oncology Group (E1996)
Greenberg, P. L., Sun, Z., Miller, K. B., Bennett, J. M., Tallman, M. S., Dewald, G., … Rowe, J. M. (2009). Treatment of myelodysplastic syndrome patients with erythropoietin with or without granulocyte colony-stimulating factor: results of a prospective randomized phase 3 trial by the Eastern Cooperative Oncology Group (E1996). BLOOD, 114(12), 2393–2400. -
Relationship of differential gene expression profiles in CD34(+) myelodysplastic syndrome marrow cells to disease subtype and progression
Sridhar, K., Ross, D. T., Tibshirani, R., Butte, A. J., & Greenberg, P. L. (2009). Relationship of differential gene expression profiles in CD34(+) myelodysplastic syndrome marrow cells to disease subtype and progression. BLOOD, 114(23), 4847–58. -
Current therapeutic approaches for patients with myelodysplastic syndromes
Greenberg, P. L. (2010). Current therapeutic approaches for patients with myelodysplastic syndromes. BRITISH JOURNAL OF HAEMATOLOGY, 150(2), 131–43. -
Prospective assessment of effects on iron-overload parameters of deferasirox therapy in patients with myelodysplastic syndromes
Greenberg, P. L., Koller, C. A., Cabantchik, Z. I., Warsi, G., Glynos, T., Paley, C., & Schiffer, C. (2010). Prospective assessment of effects on iron-overload parameters of deferasirox therapy in patients with myelodysplastic syndromes. LEUKEMIA RESEARCH, 34(12), 1560–65. -
NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes.
Greenberg, P. L., Attar, E., Bennett, J. M., Bloomfield, C. D., De Castro, C. M., Deeg, H. J., … Westervelt, P. (2011). NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes. Journal of the National Comprehensive Cancer Network , 9(1), 30–56. -
BONE-MARROW CELL MODULATION AND INHIBITION OF MYELOPOIESIS BY LARGE GRANULAR LYMPHOCYTES AND NATURAL-KILLER-CELLS
Nagler, A., & Greenberg, P. L. (1990). BONE-MARROW CELL MODULATION AND INHIBITION OF MYELOPOIESIS BY LARGE GRANULAR LYMPHOCYTES AND NATURAL-KILLER-CELLS. INTERNATIONAL JOURNAL OF CELL CLONING, 8(3), 171–83. -
Myelodysplastic Syndromes: Dissecting the Heterogeneity
Greenberg, P. L. (2011). Myelodysplastic Syndromes: Dissecting the Heterogeneity. JOURNAL OF CLINICAL ONCOLOGY, 29(15), 1937–38. -
Treatment of higher risk myelodysplastic syndrome patients unresponsive to hypomethylating agents with ON 01910.Na
Seetharam, M., Fan, A. C., Tran, M., Xu, L., Renschler, J. P., Felsher, D. W., … Greenberg, P. L. (2012). Treatment of higher risk myelodysplastic syndrome patients unresponsive to hypomethylating agents with ON 01910.Na. LEUKEMIA RESEARCH, 36(1), 98–103. -
Molecular and genetic features of myelodysplastic syndromes
Greenberg, P. L. (2012). Molecular and genetic features of myelodysplastic syndromes. INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 34(3), 215–22. -
Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes
Chen, R., Mias, G. I., Li-Pook-Than, J., Jiang, L., Lam, H. Y. K., Chen, R., … Snyder, M. (2012). Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes. CELL, 148(6), 1293–1307. -
Distinctive contact between CD34+ hematopoietic progenitors and CXCL12+ CD271+ mesenchymal stromal cells in benign and myelodysplastic bone marrow
Flores-Figueroa, E., Varma, S., Montgomery, K., Greenberg, P. L., & Gratzinger, D. (2012). Distinctive contact between CD34+ hematopoietic progenitors and CXCL12+ CD271+ mesenchymal stromal cells in benign and myelodysplastic bone marrow. LABORATORY INVESTIGATION, 92(9), 1330–41. -
Revised International Prognostic Scoring System for Myelodysplastic Syndromes
Greenberg, P. L., Tuechler, H., Schanz, J., Sanz, G., Garcia-Manero, G., Sole, F., … Haase, D. (2012). Revised International Prognostic Scoring System for Myelodysplastic Syndromes. BLOOD, 120(12), 2454–65. -
Reduced rRNA expression and increased rDNA promoter methylation in CD34(+) cells of patients with myelodysplastic syndromes
Raval, A., Sridhar, K. J., Patel, S., Turnbull, B. B., Greenberg, P. L., & Mitchell, B. S. (2012). Reduced rRNA expression and increased rDNA promoter methylation in CD34(+) cells of patients with myelodysplastic syndromes. BLOOD, 120(24), 4812–18. -
Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia.
Pollyea, D. A., Zehnder, J., Coutre, S., Gotlib, J. R., Gallegos, L., Abdel-Wahab, O., … Medeiros, B. C. (2013). Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia. Haematologica, 98(4), 591–96. -
Risk of Therapy-Related Secondary Leukemia in Hodgkin Lymphoma: The Stanford University Experience Over Three Generations of Clinical Trials
Koontz, M. Z., Horning, S. J., Balise, R., Greenberg, P. L., Rosenberg, S. A., Hoppe, R. T., & Advani, R. H. (2013). Risk of Therapy-Related Secondary Leukemia in Hodgkin Lymphoma: The Stanford University Experience Over Three Generations of Clinical Trials. JOURNAL OF CLINICAL ONCOLOGY, 31(5), 592–98. -
Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes
Pang, W. W., Pluvinage, J. V., Price, E. A., Sridhar, K., Arber, D. A., Greenberg, P. L., … Weissman, I. L. (2013). Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(8), 3011–16. -
TREATMENT OF MYELODYSPLASTIC SYNDROMES WITH RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR - A PHASE I-II TRIAL
Negrin, R. S., HAEUBER, D. H., Nagler, A., Olds, L. C., Donlon, T., SOUZA, L. M., & Greenberg, P. L. (1989). TREATMENT OF MYELODYSPLASTIC SYNDROMES WITH RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR - A PHASE I-II TRIAL. ANNALS OF INTERNAL MEDICINE, 110(12), 976–84. -
BIOLOGIC NATURE OF THE MYELODYSPLASTIC SYNDROMES
Greenberg, P. L. (1987). BIOLOGIC NATURE OF THE MYELODYSPLASTIC SYNDROMES. ACTA HAEMATOLOGICA, 78, 94–99. -
SELECTIVE GENERATION OF ERYTHROID BURST PROMOTING ACTIVITY BY RECOMBINANT INTERLEUKIN-2 STIMULATED HUMAN LYMPHOCYTES-T AND NATURAL-KILLER CELLS
Skettino, S., Phillips, J., Lanier, L., Nagler, A., & Greenberg, P. (1988). SELECTIVE GENERATION OF ERYTHROID BURST PROMOTING ACTIVITY BY RECOMBINANT INTERLEUKIN-2 STIMULATED HUMAN LYMPHOCYTES-T AND NATURAL-KILLER CELLS. BLOOD, 71(4), 907–14. -
RECEPTOR-BINDING AND MITOGENIC EFFECTS OF INSULIN AND INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II FOR HUMAN MYELOID LEUKEMIC-CELLS
PEPE, M. G., Ginzton, N. H., Lee, P. D. K., Hintz, R. L., & Greenberg, P. L. (1987). RECEPTOR-BINDING AND MITOGENIC EFFECTS OF INSULIN AND INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II FOR HUMAN MYELOID LEUKEMIC-CELLS. JOURNAL OF CELLULAR PHYSIOLOGY, 133(2), 219–27. -
IMMUNOLOGICAL SELECTION OF HEMATOPOIETIC PRECURSOR CELLS UTILIZING ANTIBODY-MEDIATED PLATE BINDING (PANNING)
Greenberg, P. L., Baker, S., Link, M., & Minowada, J. (1985). IMMUNOLOGICAL SELECTION OF HEMATOPOIETIC PRECURSOR CELLS UTILIZING ANTIBODY-MEDIATED PLATE BINDING (PANNING). BLOOD, 65(1), 190–97. -
EFFECTS OF GRANULOCYTE-COLONY-STIMULATING FACTOR THERAPY ON IN-VITRO HEMATOPOIESIS IN MYELODYSPLASTIC SYNDROMES
Nagler, A., MacKichan, M. L., Negrin, R. S., Donlon, T., & Greenberg, P. L. (1995). EFFECTS OF GRANULOCYTE-COLONY-STIMULATING FACTOR THERAPY ON IN-VITRO HEMATOPOIESIS IN MYELODYSPLASTIC SYNDROMES. LEUKEMIA, 9(1), 30–39. -
ENRICHMENT OF BONE-MARROW AND BLOOD PROGENITOR (CD34(+)) CELLS BY DENSITY GRADIENTS WITH SUFFICIENT YIELDS FOR TRANSPLANTATION
Schriber, J. R., DEJBAKHSHJONES, S., KUSNIERZGLAZ, C. R., Ginzton, N., Still, B., Negrin, R. S., … Strober, S. (1995). ENRICHMENT OF BONE-MARROW AND BLOOD PROGENITOR (CD34(+)) CELLS BY DENSITY GRADIENTS WITH SUFFICIENT YIELDS FOR TRANSPLANTATION. EXPERIMENTAL HEMATOLOGY, 23(9), 1024–29. -
TREATMENT OF THE ANEMIA OF MYELODYSPLASTIC SYNDROMES USING RECOMBINANT HUMAN GRANULOCYTE-COLONY-STIMULATING FACTOR IN COMBINATION WITH ERYTHROPOIETIN
Negrin, R. S., Stein, R., Vardiman, J., Doherty, K., Cornwell, J., Krantz, S., & Greenberg, P. L. (1993). TREATMENT OF THE ANEMIA OF MYELODYSPLASTIC SYNDROMES USING RECOMBINANT HUMAN GRANULOCYTE-COLONY-STIMULATING FACTOR IN COMBINATION WITH ERYTHROPOIETIN. BLOOD, 82(3), 737–43. -
MODULATION OF APOPTOSIS IN HUMAN MYELOID LEUKEMIC-CELLS BY GM-CSF
Han, J. H., Gileadi, C., Rajapaksa, R., Kosek, J., & Greenberg, P. L. (1995). MODULATION OF APOPTOSIS IN HUMAN MYELOID LEUKEMIC-CELLS BY GM-CSF. EXPERIMENTAL HEMATOLOGY, 23(3), 265–72. -
Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: Evidence for in vivo synergy
Negrin, R. S., Stein, R., Doherty, K., Cornwell, J., Vardiman, J., Krantz, S., & Greenberg, P. L. (1996). Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: Evidence for in vivo synergy. BLOOD, 87(10), 4076–81. -
Biologic and clinical implications of marrow culture studies in the myelodysplastic syndromes
Greenberg, P. L. (1996). Biologic and clinical implications of marrow culture studies in the myelodysplastic syndromes. SEMINARS IN HEMATOLOGY, 33(2), 163–75. -
Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells
Rajapaksa, R., Ginzton, N., Rott, L. S., & Greenberg, P. L. (1996). Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells. BLOOD, 88(11), 4275–87. -
GM-CSF accelerates neutrophil recovery after autologous hematopoietic stem cell transplantation
Greenberg, P., Advani, R., Keating, A., Gulati, S. C., Nimer, S., Champlin, R., … Cuffie, C. (1996). GM-CSF accelerates neutrophil recovery after autologous hematopoietic stem cell transplantation. BONE MARROW TRANSPLANTATION, 18(6), 1057–64. -
International scoring system for evaluating prognosis in myelodysplastic syndromes
Greenberg, P., Cox, C., LEBEAU, M. M., Fenaux, P., Morel, P., Sanz, G., … Bennett, J. (1997). International scoring system for evaluating prognosis in myelodysplastic syndromes. BLOOD, 89(6), 2079–88. -
Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression
Davis, R. E., & Greenberg, P. L. (1998). Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression. LEUKEMIA RESEARCH. NASHVILLE,TN,TN,TN,TN,TN,TN,TN,TN,TN,TN,TN: PERGAMON-ELSEVIER SCIENCE LTD. -
Risk factors and their relationship to prognosis in myelodysplastic syndromes
Greenberg, P. L. (1998). Risk factors and their relationship to prognosis in myelodysplastic syndromes. LEUKEMIA RESEARCH, 22, S3–S6. -
Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment
Greenberg, P. L. (1998). Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment. LEUKEMIA RESEARCH, 22(12), 1123–36. -
Programmed cell death (apoptosis) as a mechanism for regulating haematopoietic cell population size
Greenberg, P. L. (1992). Programmed cell death (apoptosis) as a mechanism for regulating haematopoietic cell population size. Focus on Growth Factors, 3(2). -
NCCN Practice Guidelines for Myelodysplastic Syndromes
NCCN Practice Guidelines for Myelodysplastic Syndromes. (1998). Oncology, 12(11A). -
The Myelodysplastic Syndromes .
Greenberg, P. (2000). The Myelodysplastic Syndromes . HEMATOLOGY:BASIC PRINCIPLES AND PRACTICE 3rd Ed., Hoffman R, Benz E, Shattil S, Furie B, Cohen H, Silberstein L, McGlave P, Eds. Churchill Livingstone, NY, -
A Decision Analysis of Allogeneic Bone Marrow Transplantation for the Myelodysplastic Syndromes: Delayed Transplantation for Low Risk Myelodysplasia is Associated with Improved Outcome
A Decision Analysis of Allogeneic Bone Marrow Transplantation for the Myelodysplastic Syndromes: Delayed Transplantation for Low Risk Myelodysplasia is Associated with Improved Outcome. (2004). Blood, 104. -
Novel biospecific agents for the treatment of myelodysplastic syndromes.
Novel biospecific agents for the treatment of myelodysplastic syndromes. (2003). J Nat Comprehensive Cancer Network, 1. -
Myelodysplastic Syndromes: Clinical and Biological Advances
Greenberg, P. L. L. (2006). Myelodysplastic Syndromes: Clinical and Biological Advances. Cambridge University Press, Cambridge, England. -
Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia.
Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. (2006). Blood, 108. -
Phase II Study of Lenalidomide in Transfusion-Dependent, Low and Intermediate-1-Risk Myelodysplastic Syndromes with Normal and Abnormal Karyotypes Other than Deletion 5q.
Phase II Study of Lenalidomide in Transfusion-Dependent, Low and Intermediate-1-Risk Myelodysplastic Syndromes with Normal and Abnormal Karyotypes Other than Deletion 5q. (2008). Blood, 111. -
Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): A 1-year prospective study.
Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): A 1-year prospective study. (2008). Eur J Haematol, 80. -
Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF
Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF. (2008). Blood, 111. -
International MDS Risk Analysis Workshop (IMRAW)/IPSS Re-analyzed: Impact of cytopenias on clinical outcomes in Myelodysplastic Syndrome
Kao, J. M., McMillan, A., & Greenberg, P. L. (2008). International MDS Risk Analysis Workshop (IMRAW)/IPSS Re-analyzed: Impact of cytopenias on clinical outcomes in Myelodysplastic Syndrome. Am J Hematology, 83. -
A phase II study of the farnesyltransferase inhibitor tipifarnib in elderly patients with previously untreated poor-risk acute myeloid leukemia
A phase II study of the farnesyltransferase inhibitor tipifarnib in elderly patients with previously untreated poor-risk acute myeloid leukemia. (2006). Blood, 108. -
Hematologic and cytogenetic response to lenalidomide in myelodysplastic syndrome with chromosome 5q deletion.
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The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
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Frequency of del(12p) is Commonly Underestimated in Myelodysplastic Syndromes: Results from a German Diagnostic Study in Comparison with an International Control Group
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p53 Mutant Independently Impacts Risk: Analysis of Deletion 5q, Lower-Risk Myelodysplastic Syndromes (MDS) Patients Treated with Lenalidomide (LEN) in the MDS-004 Study
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A PHASE IB STUDY EVALUATING THE SAFETY AND CLINICAL ACTIVITY OF ATEZOLIZUMAB ALONE AND IN COMBINATION WITH AZACITIDINE IN PATIENTS WITH RELAPSED OR REFRACTORY MYELODYSPLASTIC SYNDROMES
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Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q)
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The classical nature of distinctive CMML monocytes
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Comprehensive Analysis of Safety: Rigosertib in 557 Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)
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Frequency and Prognostic Significance of Cytogenetic Abnormalities in 1269 Patients with Therapy-Related Myelodysplastic Syndrome - a Study of the International Working Group (IWG-PM) for Myelodysplastic Syndromes (MDS)
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Single-cell network profiling (SCNP) to evaluate the proteomic profiles associated with ON 01910.Na treatment of MDS patients (Pts)
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Nano-scale phospho-proteomic analysis to define diagnostic signatures and biomarkers of therapeutic activity in cancer
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RANDOMIZED PHASE III STUDY OF IV RIGOSERTIB VERSUS BEST SUPPORTIVE CARE (BSC) IN PATIENTS WITH HIGHER-RISK MDS (HR-MDS) AFTER FAILURE OF HYPOMETHYLATING AGENTS (HMAS)
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BONE MARROW BLAST (BMBL) RESPONSE CORRELATES WITH OVERALL SURVIVAL IN RIGOSERTIB-TREATED PATIENTS WITH HIGHER-RISK MDS AFTER FAILURE OF HYPOMETHYLATING AGENTS (HMAS): A NEW RESPONSE CRITERION?
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Cytogenetic classification according to IPSS/-R is possible from peripheral blood in patients with Myelodysplastic Syndromes
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Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee
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An Analysis of Prognostic Markers and the Performance of Scoring Systems in 1837 Patients with Therapy-Related Myelodysplastic Syndrome - a Study of the International Working Group (IWG-PM) for Myelodysplastic Syndromes (MDS)
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Prognostic Impact of Rare Single Abnormalities in Myelodysplastic Syndromes
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Underestimation of 12p-deletion in myelodysplastic syndromes? Results from a German diagnostic study in comparison with an international control group
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Prognostic significance of rare single abnormalities in Myelodysplastic Syndromes
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PROGNOSTIC AND PREDICTIVE VALUE OF IPSS-R IN ASSESSING OVERALL SURVIVAL (OS) IN A PHASE III STUDY OF RIGOSERTIB IN SECOND-LINE HIGHER-RISK (HR) MDS PATIENTS
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CORRELATION OF OVERALL SURVIVAL (OS) WITH BONE MARROW BLAST (BMBL) RESPONSE IN PATIENTS (PTS) WITH MYELODYSPLASTIC SYNDROMES (MDS)
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OVERALL SURVIVAL (OS) AND BASELINE DISEASE CHARACTERISTICS IN MDS PATIENTS WITH PRIMARY HMA FAILURE IN A RANDOMIZED, CONTROLLED, PHASE III STUDY OF RIGOSERTIB
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Evaluation of hematopoietic stem/progenitor cells in MDS reveals novel pathogenic mechanisms
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Revised International Prognostic Scoring System (IPSS-R) for MDS: Update
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IL1RAP as functionally relevant target for stem-cell directed therapy in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).
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Overall survival (OS) and baseline disease characteristics in MDS patients with primary HMA failure in a randomized, controlled, phase III study of rigosertib.
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Correlation of overall survival (OS) with bone marrow blast (BMBL) response in patients (pts) with myelodysplastic syndrome
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Relationship of Bone Marrow Blast (BMBL) Response to Overall Survival (OS) in Patients with Higher-Risk Myelodysplastic Syndrome (HR-MDS) Treated with Rigosertib after Failure of Hypomethylating Agents (HMAs)
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Profiling Myelodysplastic Syndromes By Mass Cytometry Demonstrates Distinct Immunophenotypic Aberrancies in Stem and Progenitor Populations
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Genomic Microarray Alterations Add Prognostic Power to the IPSS-R in MDS with Normal Karyotype
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Overall Survival and Subgroup Analysis from a Randomized Phase III Study of Intravenous Rigosertib Versus Best Supportive Care (BSC) in Patients (pts) with Higher-Risk Myelodysplastic Syndrome (HR-MDS) after Failure of Hypomethylating Agents (HMAs)
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Transcriptomic Evaluation of CD34+Marrow Cells from Myelodysplastic Syndrome (MDS) Patients
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KB004, a Novel Non-Fucosylated Humaneered (R) Antibody, Targeting EphA3, Is Active and Well Tolerated in a Phase I/II Study of Advanced Hematologic Malignancies
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TP53 Mutation Status Divides MDS Patients with Complex Karyotypes into Distinct Prognostic Risk Groups: Analysis of Combined Datasets from the International Working Group for MDS-Molecular Prognosis Committee
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MYELODYSPLASTIC SYNDROMES: OLD AND NEW CLASSIFICATION AND PROGNOSTIC SYSTEMS
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Is IPSS/IPSS-R cytogenetic classification possible from peripheral blood in MDS patients? Comparative results from a prospective German diagnostic study with the data set of an international collaboration
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Revised International Prognostic Scoring System (IPSS-R) for primary treated myelodysplastic syndromes (MDS) patients: A report from the IWG-PM
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Validation of the IPSS-R in lenalidomide-treated, lower-risk myelodysplastic syndrome patients with del(5q)
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Application of the French prognostic score (FPS) to assess overall survival (OS) in a US-based cohort of patients (pts) treated with azacitidine (Aza).
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Efficacy and tolerability of lenalidomide (LEN) in patients (pts) 75 and older versus those younger than 75 with RBC transfusion-dependent low/int-1-risk MDS and del 5q
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Randomized, dose-escalation study of the p38 alpha MAPK inhibitor SCIO-469 in patients with myelodysplastic syndrome
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Final Phase I/II Results of Rigosertib (ON 01910.Na) Hematological Effects in Patients with Myelodysplastic Syndrome and Correlation with Overall Survival
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Do Erythropoiesis-Stimulating Agents (ESAs) Affect Survival in Anemic Patients with Myelodysplastic Syndromes (MDS)?
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A Decision Analysis of Reduced-Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Older Patients with De-Novo Myelodysplastic Syndrome (MDS): Early Transplantation Offers Survival Benefit in Higher-Risk MDS
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Characterization and prognostic significance of cytogenetically unrelated clones in myelodysplastic syndromes and acute myeloid leukemia
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Prognostic Impact of Monosomy 7 as a Single Anomaly In Primary MDS - Reclassification From Poor to Intermediate Prognosis
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Unrelated Clones In Myelodysplastic Syndromes and Acute Myeloid Leukemia - Characterization and Prognostic Relevance
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A 10 Day Schedule of Azacitidine Induces More Complete Cytogenetic Remissions Than the Standard Schedule In Myelodysplasia and Acute Myeloid Leukemia with Myelodysplasia-Related Changes: Results of the E1905 US Leukemia Intergroup Study
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Loss of the Y Chromosome in MDS - Age-Related Phenomenon or Clonal Abnormality?
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Overall Survival In Myelodysplastic Syndrome or Acute Myeloid Leukemia Patients Treated with On 01910.Na Correlates with Bone Marrow Blast Response.
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Loss of the Y Chromosome in MDS: Clonal abnormality or age-related accident?
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Unrelated clones in AML/MDS - characterisation and prognostic relevance
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PROPOSAL OF A NEW, COMPREHENSIVE CYTOGENETIC SCORING SYSTEM FOR PRIMARY MDS
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Single Cell Network Profiling (SCNP) to Evaluate the Mechanism of Action of ON 01910.Na, A Novel Clinical Trial Stage Compound.
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Cytogenetic Risk Features in MDS-Update and Present State.
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Efficacy and Safety of Romiplostim in Patients with Low or Intermediate-Risk Myelodysplastic Syndrome (MDS) Receiving Decitabine
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Change in liver iron concentration (LIC), serum ferritin (SF) and labile plasma iron (LPI) over 1 year of deferasirox (Exjade (R)) therapy in a cohort of patients with MDS
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Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS
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Clonal architecture in patients with myelodysplastic syndromes and double or minor complex abnormalities: Detailed analysis of clonal composition, involved abnormalities, and prognostic significance
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Single-Cell Mutational Profiling Describes the Molecular Heterogeneity of Clonal Evolution in MDS during Therapy and Relapse
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PD-L1 Blockade with Atezolizumab in Higher-Risk Myelodysplastic Syndrome: An Initial Safety and Efficacy Analysis
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Deferasirox (Exjade (R), ICL670) demonstrates dose-related effects on body iron levels related to transfusional iron intake in transfusion-dependent anemia
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Phase II trial of darbepoetin alfa in myelodysplastic syndrome (MDS): Preliminary efficacy, safety, and in vitro results.
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MONOCLONAL-ANTIBODY CHARACTERIZATION OF HUMAN MYELOID COLONY-FORMING CELLS (CFU-GM)
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MULTIVARIATE-ANALYSIS OF FACTORS PREDICTING OUTCOME OF TREATMENT FOR ADULTS WITH ACUTE MYELOGENOUS LEUKEMIA (AML)
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Problematic WHO reclassification of myelodysplastic syndromes
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Soluble TNF receptor fusion protein (TNFR : Fc; Enbrel) in the treatment of patients with myelodysplastic syndrome (MDS).
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Amifostine in combination with cytokines stimulates in vitro hemopoiesis in myelodysplastic syndromes (MDS).
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International prognostic scoring system and other prognostic systems for myelodysplastic syndromes - Response
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Efficacy of G-CSF and EPO on the anaemia in patients with myelodysplastic syndromes (MDS).
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International workshop consensus risk analysis system for myelodysplastic syndromes (MDS).
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GRANULOCYTE-COLONY-STIMULATING FACTOR (G-CSF) PLUS ERYTHROPOIETIN (EPO) FOR THE MAINTENANCE TREATMENT OF THE ANEMIA OF MYELODYSPLASTIC SYNDROMES (MDS)
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BCL-2 EXPRESSION BY MYELOID PRECURSORS IN MYELODYSPLASTIC SYNDROMES (MDS) - IMMUNOSTAINING OF BONE-MARROW (BM) BIOPSIES
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ONCOPROTEIN EXPRESSION AND APOPTOSIS IN MYELODYSPLASTIC SYNDROME (MDS) MARROW-CELLS
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CLONALITY ANALYSIS IN MYELODYSPLASIA (MDS) PATIENTS TREATED WITH G-CSF
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THE PROGNOSTIC-SIGNIFICANCE OF CYTOGENETIC ABNORMALITIES IN MYELODYSPLASTIC SYNDROMES (MDS) FOLLOWING G-CSF
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GRANULOCYTE COLONY STIMULATING FACTOR (G-CSF) PLUS ERYTHROPOIETIN (EPO) TREATMENT OF MYELODYSPLASTIC SYNDROMES
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INVITRO-INVIVO CORRELATIONS OF ERYTHROID RESPONSES TO G-CSF PLUS ERYTHROPOIETIN (EPO) IN MYELODYSPLASTIC SYNDROMES (MDS)
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THE NATURE AND EVOLVING TREATMENT OF MYELODYSPLASTIC SYNDROMES
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Safety and tolerability of eltrombopag versus placebo for treatment of thrombocytopenia in patients with advanced myelodysplastic syndromes or acute myeloid leukaemia: a multicentre, randomised, placebo-controlled, double-blind, phase 1/2 trial.
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Granulocyte-monocyte and Granulocyte-Colony Stimulating Factors in Myelodysplastic Syndromes.
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Clinical effectiveness and safety of erythropoietin-stimulating agents for the treatment of low- and intermediate-1-risk myelodysplastic syndrome: a systematic literature review
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Molecular pathophysiology of the myelodysplastic syndromes: insights for targeted therapy
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Recurrent drug sensitivity patterns in myelodysplastic syndrome patients are recapitulated by ex vivo drug response profiling
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Single-cell mutational profiling of clonal evolution in myelodysplastic syndromes (MDS) during therapy and disease progression
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TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups
Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M. A., … Bejar, R. (2019). TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. LEUKEMIA, 33(7), 1747–58. -
MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-beta pathways.
Youn, M., Huang, H., Chen, C., Kam, S., Wilkes, M. C., Chae, H.-D., … Sakamoto, K. M. (2019). MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-beta pathways. Blood Advances, 3(18), 2751–63. -
Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions
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PROPOSAL OF A NEW, COMPREHENSIVE CYTOGENETIC SCORING SYSTEM FOR PRIMARY MDS
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CHRONICALLY TRANSFUSED MYELODYSPLASTIC SYNDROMES (MDS) PATIENTS HAVE SEVERE IRON BURDEN: DEFERASIROX TREATMENT REDUCES IRON OVERLOAD AND IMPROVES LIVER FUNCTION
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Comparison of Patient Age Groups in Transplantation for Myelodysplastic Syndrome: The Medicare Coverage With Evidence Development Study.
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Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.
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Profiling myelodysplastic syndromes by mass cytometry demonstrates abnormal progenitor cell phenotype and differentiation.
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Wide variation in use and interpretation of gene mutation profiling panels among health care providers of patients with myelodysplastic syndromes: results of a large web-based survey.
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Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial.
Angelucci, E., Li, J., Greenberg, P., Wu, D., Hou, M., Montano Figueroa, E. H., … Garcia-Manero, G. (2020). Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial. Annals of Internal Medicine. -
SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM).
Malcovati, L., Stevenson, K., Papaemmanuil, E., Neuberg, D., Bejar, R., Boultwood, J., … Cazzola, M. (2020). SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM). Blood. -
Myelodysplastic syndromes: moving towards personalized management.
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Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience.
Azizi, A., Ediriwickrema, A., Dutta, R., Patel, S. A., Shomali, W., Medeiros, B., … Zhang, T. (2020). Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience. Leukemia & Lymphoma, 1–8. -
Ex vivo drug screening defines novel drug sensitivity patterns for informing personalized therapy in myeloid neoplasms.
Spinner, M. A., Aleshin, A., Santaguida, M. T., Schaffert, S. A., Zehnder, J. L., Patterson, A. S., … Greenberg, P. L. (2020). Ex vivo drug screening defines novel drug sensitivity patterns for informing personalized therapy in myeloid neoplasms. Blood Advances, 4(12), 2768–78. -
Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS.
Kuendgen, A., Nomdedeu, M., Tuechler, H., Garcia-Manero, G., Komrokji, R. S., Sekeres, M. A., … Sanz, G. (2020). Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS. Leukemia. -
Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations.
Feurstein, S., Adegunsoye, A., Mojsilovic, D., Vij, R., West DePersia, A. H., Rajagopal, P. S., … Churpek, J. E. (2020). Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations. Blood Advances, 4(19), 4873–86. -
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes (vol 26, pg 1549, 2020)
Bernard, E., Nannya, Y., Hasserjian, R. P., Devlin, S. M., Tuechler, H., Medina-Martinez, J. S., … Papaemmanuil, E. (2021). Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes (vol 26, pg 1549, 2020). NATURE MEDICINE. -
A Retrospective Analysis From Patients Treated in The MEDALIST Study: Safety and Efficacy Of Luspatercept Treatment In Patients With Myelodysplastic Syndrome/Myeloproliferative Neoplasm With Ring Sideroblasts And Thrombocytosis
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Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms.
Steensma, D. P., Wermke, M., Klimek, V. M., Greenberg, P. L., Font, P., Komrokji, R. S., … Platzbecker, U. (2021). Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms. Leukemia. -
Metchnikoff's inflamed legacy: the dysplastic nature of myelodysplastic syndrome's innate Immunity.
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COMPARISON OF CYTOGENETIC ABERRATIONS IN 1590 PATIENTS WITH THERAPY-RELATED MDS (T-MDS) AND 4738 PATIENTS FROM THE REVISED INTERNATIONAL PROGNOSTIC SCORING SYSTEM DATABASE WITH PRIMARY-MDS (P-MDS)
Kuendgen, A., Nomdedeu, M., Tuechler, H., Garcia-Manero, G., Komrokji, R., Sekeres, M., … Sanz, G. (2021). COMPARISON OF CYTOGENETIC ABERRATIONS IN 1590 PATIENTS WITH THERAPY-RELATED MDS (T-MDS) AND 4738 PATIENTS FROM THE REVISED INTERNATIONAL PROGNOSTIC SCORING SYSTEM DATABASE WITH PRIMARY-MDS (P-MDS). LEUKEMIA RESEARCH. PERGAMON-ELSEVIER SCIENCE LTD. -
Atezolizumab alone or in combination did not demonstrate a favorable risk-benefit profile in myelodysplastic syndrome.
Gerds, A. T., Scott, B. L., Greenberg, P. L., Lin, T. L., Pollyea, D. A., Verma, A. K., … Donnellan, W. B. (1800). Atezolizumab alone or in combination did not demonstrate a favorable risk-benefit profile in myelodysplastic syndrome. Blood Advances. -
NCCN Guidelines Insights: Myelodysplastic Syndromes, Version 3.2022.
Greenberg, P. L., Stone, R. M., Al-Kali, A., Bennett, J. M., Borate, U., Brunner, A. M., … Hochstetler, C. (2022). NCCN Guidelines Insights: Myelodysplastic Syndromes, Version 3.2022. Journal of the National Comprehensive Cancer Network : JNCCN, 20(2), 106–117. -
Luspatercept for myelodysplastic syndromes/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis.
Komrokji, R. S., Platzbecker, U., Fenaux, P., Zeidan, A. M., Garcia-Manero, G., Mufti, G. J., … Verma, A. (2022). Luspatercept for myelodysplastic syndromes/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis. Leukemia. -
Longer-term benefit of luspatercept in transfusion-dependent lower-risk myelodysplastic syndromes with ring sideroblasts.
Zeidan, A. M., Platzbecker, U., Garcia-Manero, G., Sekeres, M. A., Fenaux, P., DeZern, A. E., … Komrokji, R. S. (2022). Longer-term benefit of luspatercept in transfusion-dependent lower-risk myelodysplastic syndromes with ring sideroblasts. Blood. -
MDS and MDS/MPN Genomic Subgroups Demonstrate Differential E x Vivo Drug Sensitivity
Spinner, M. A., Schaffert, S. A., Stehr, H., TSantaguida, M., Kita, R., Aleshin, A., … Greenberg, P. L. (2021). MDS and MDS/MPN Genomic Subgroups Demonstrate Differential E x Vivo Drug Sensitivity. BLOOD. AMER SOC HEMATOLOGY. -
An agenda to advance research in MDS: A TOP 10 Priority List from the first international workshop in MDS (iwMDS).
Stahl, M., Abdel-Wahab, O., Wei, A. H., Savona, M. R., Xu, M. L., Xie, Z., … Zeidan, A. M. (2022). An agenda to advance research in MDS: A TOP 10 Priority List from the first international workshop in MDS (iwMDS). Blood Advances. -
Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes.
Zeidan, A. M., Bewersdorf, J. P., Buckstein, R., Sekeres, M. A., Steensma, D. P., Platzbecker, U., … Santini, V. (2022). Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes. Leukemia. -
Recent Clinical and Molecular Advances for the Classification of Myelodysplastic Neoplasms.
DeZern, A. E., & Greenberg, P. L. (2022). Recent Clinical and Molecular Advances for the Classification of Myelodysplastic Neoplasms. Journal of the National Comprehensive Cancer Network : JNCCN, 20(12), 1280–1283. -
Myelodysplastic syndromes, thy name is heterogeneity.
Greenberg, P. L. (2023). Myelodysplastic syndromes, thy name is heterogeneity. British Journal of Haematology. -
Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories
Pfeilstocker, M., Tuechler, H., Ades, L., Cermak, J., Chermat, F., Della Porta, M. G., … Greenberg, P. L. (2022). Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories. BLOOD. AMER SOC HEMATOLOGY. -
Correlation of Mutational Profiles and Cytogenetics with Morphologic Dysplasia in Myelodysplastic Syndromes
Kumar, J., Khanna, V., Lu, R., Stehr, H., Spinner, M. A., Silva, O., … Tan, B. (2022). Correlation of Mutational Profiles and Cytogenetics with Morphologic Dysplasia in Myelodysplastic Syndromes. BLOOD. AMER SOC HEMATOLOGY. -
Incidence, Clinical Associations, and Co-Mutation Patterns of UBA1 Mutations in MDS
Sirenko, M., Bernard, E., Beck, D. B., Creignou, M., Domenico, D., Farina, A., … Papaemmanuil, E. (2022). Incidence, Clinical Associations, and Co-Mutation Patterns of UBA1 Mutations in MDS. BLOOD. AMER SOC HEMATOLOGY. -
A STEP TOWARDS IDENTIFICATION AND CAUSAL INTERPRETATION OF THERAPY-RELATED MDS (T-MDS)
Kuendgen, A., Nomdedeu, M., Tuechler, H., Garcia-Manero, G., Komrokji, R., Sekeres, M., … Sanz, G. (2023). A STEP TOWARDS IDENTIFICATION AND CAUSAL INTERPRETATION OF THERAPY-RELATED MDS (T-MDS). LEUKEMIA RESEARCH. PERGAMON-ELSEVIER SCIENCE LTD. -
ACCELERATED FAILURE TIME MODELS AS A CLINICALLY PLAUSIBLE WAY TO DESCRIBE SURVIVAL IN MDS - AN ANALYSIS OF THE IWG-PM DATABASE
Pfeilstoecker, M., Tuechler, H., Ades, L., Cermak, J., Chermat, F., Della Porta, M., … Greenberg, P. (2023). ACCELERATED FAILURE TIME MODELS AS A CLINICALLY PLAUSIBLE WAY TO DESCRIBE SURVIVAL IN MDS - AN ANALYSIS OF THE IWG-PM DATABASE. LEUKEMIA RESEARCH. PERGAMON-ELSEVIER SCIENCE LTD. -
GENOMIC CLASSIFICATION OF MYELODYSPLASTIC SYNDROMES
Bernard, E., Hasserjian, R., Greenberg, P., Ossa, J. A., Creignou, M., Nannya, Y., … Papaemmanuil, E. (2023). GENOMIC CLASSIFICATION OF MYELODYSPLASTIC SYNDROMES. LEUKEMIA RESEARCH. PERGAMON-ELSEVIER SCIENCE LTD. -
Prognostication and risk stratification of patients with myelodysplastic syndromes.
DeZern, A., & Greenberg, P. L. (2023). Prognostication and risk stratification of patients with myelodysplastic syndromes. Blood. -
Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS).
Stahl, M., Bewersdorf, J. P., Xie, Z., Porta, M. G., Komrokji, R., Xu, M. L., … Zeidan, A. M. (2023). Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS). Blood Reviews, 101128. -
SIRT7 IMPROVES HEMATOPOIESIS IN MYELODYSPLASTIC SYNDROME THROUGH REGULATING MITOCHONDRIAL STRESS
Wang, Y., Maruichi, A., song, Z., Greenberg, P., & Chen, D. (2023). SIRT7 IMPROVES HEMATOPOIESIS IN MYELODYSPLASTIC SYNDROME THROUGH REGULATING MITOCHONDRIAL STRESS. EXPERIMENTAL HEMATOLOGY. ELSEVIER SCIENCE INC. -
The clinical, molecular, and prognostic features of the 2022 WHO and ICC classification systems for myelodysplastic neoplasms.
Khanna, V., Lu, R., Kumar, J., Molina, A., Stehr, H., Spiteri, E., … Greenberg, P. L. (2023). The clinical, molecular, and prognostic features of the 2022 WHO and ICC classification systems for myelodysplastic neoplasms. Leukemia Research, 136, 107433. -
How we reduce and treat post-transplant relapse of MDS.
Mina, A., Greenberg, P. L., & Deeg, H. J. (2024). How we reduce and treat post-transplant relapse of MDS. Blood. -
Molecular International Prognostic Scoring System for Myelodysplastic Syndromes.
Bernard, E., Tuechler, H., Greenberg, P. L., Hasserjian, R. P., Arango Ossa, J. E., Nannya, Y., … Papaemmanuil, E. (2022). Molecular International Prognostic Scoring System for Myelodysplastic Syndromes. NEJM Evidence, 1(7), EVIDoa2200008. -
Shared and distinct mechanisms of UBA1 inactivation across different diseases.
Collins, J. C., Magaziner, S. J., English, M., Hassan, B., Chen, X., Balanda, N., … Werner, A. (2024). Shared and distinct mechanisms of UBA1 inactivation across different diseases. The EMBO Journal. -
Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications
Bernard, E., Hasserjian, R., Greenberg, P. L., Ossa, J. E. A., Creignou, M., Nannya, Y., … Papaemmanuil, E. (2023). Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications. BLOOD. AMER SOC HEMATOLOGY. -
Safety and Preliminary Efficacy of DFV890 in Adult Patients with Myeloid Diseases: A Phase 1b Study
Garcia-Manero, G., Ooi, M., Lao, Z., Gill, H., Abaza, Y., Stahl, M., … Woo, J. (2023). Safety and Preliminary Efficacy of DFV890 in Adult Patients with Myeloid Diseases: A Phase 1b Study. BLOOD. AMER SOC HEMATOLOGY. -
p53 immunohistochemistry as an ancillary tool for rapid assessment of residual disease in TP53-mutated acute myeloid leukemia and myelodysplastic syndromes.
Brar, N., Lawrence, L., Fung, E., Zehnder, J. L., Greenberg, P. L., Mannis, G. N., … Fernandez-Pol, S. (2024). p53 immunohistochemistry as an ancillary tool for rapid assessment of residual disease in TP53-mutated acute myeloid leukemia and myelodysplastic syndromes. American Journal of Clinical Pathology. -
Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes.
Sirenko, M., Bernard, E., Creignou, M., Domenico, D., Farina, A., Arango Ossa, J. E., … Pinheiro, R. F. (2024). Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes. Blood. -
Towarda more patient-centered drug development process in clinical trials for patients with myelodysplastic syndromes/neoplasms (MDS): Practical considerations from the International Consortium for MDS (icMDS).
Efficace, F., Buckstein, R., Abel, G. A., Giesinger, J. M., Fenaux, P., Bewersdorf, J. P., … Zeidan, A. M. (2024). Towarda more patient-centered drug development process in clinical trials for patients with myelodysplastic syndromes/neoplasms (MDS): Practical considerations from the International Consortium for MDS (icMDS). HemaSphere, 8(5), e69. -
Molecular Taxonomy of Myelodysplastic Syndromes and its Clinical Implications.
Bernard, E., Hasserjian, R. P., Greenberg, P. L., Arango Ossa, J. E., Creignou, M., Tuechler, H., … Papaemmanuil, E. (2024). Molecular Taxonomy of Myelodysplastic Syndromes and its Clinical Implications. Blood. -
Contemporary Approach to The Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes- Recommendations from The International Consortium for MDS (icMDS).
Aakash, F., Gisriel, S. D., Zeidan, A. M., Bennett, J. M., Bejar, R., Bewersdorf, J. P., … Loghavi, S. (2024). Contemporary Approach to The Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes- Recommendations from The International Consortium for MDS (icMDS). Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 100615.
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Myelodysplastic syndromes.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Phase II Cont. IV of ON 01910.Na in MDS w/ Trisomy 8/Intermed-1, 2/High Risk
- Tipifarnib in Treating Patients With Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or Undifferentiated Myeloproliferative Disorders
- Tipifarnib in Treating Patients With Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or Undifferentiated Myeloproliferative Disorders
- Efficacy and Safety of ON 01910.Na in Myelodysplastic Syndrome (MDS) Patients With Trisomy 8 or Classified as Intermediate-1, -2 or High Risk
- Bevacizumab in Treating Patients With Myelodysplastic Syndrome
- Magrolimab + Azacitidine Versus Azacitidine + Placebo in Untreated Participants With Myelodysplastic Syndrome (MDS)
- Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden
- A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
Practice Locations
Hematologic Cancer Program Palo Alto, CA
Palo Alto, CAHematologic Cancer Program
875 Blake Wilbur Dr
Palo Alto , CA 94304
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