Biography
Professional Summary
Education & Certifications
- Medical Education: Stanford University School of Medicine (2008) CA
- Residency: Stanford University Internal Medicine Residency (2010) CA
- Internship: Stanford University Internal Medicine Residency (2009) CA
- Fellowship: Stanford University Hematology and Oncology Fellowship (2013) CA
- Board Certification: American Board of Internal Medicine, Hematology (2016)
Honors & Awards
- Amy Streizer Manasevit Scholar, National Donor Marrow Program and American Society for Blood and Marrow Transplantation (2013)
- Beckman Center Technology Grant, Stanford University (2014)
- Career Development Award, JDRF (2017)
- Young Investigator Award, American Society of Blood and Marrow Transplantation (2011)
Publications
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Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
Akbari, O., Freeman, G. J., Meyer, E. H., Greenfield, E. A., Chang, T. T., Sharpe, A. H., … Umetsu, D. T. (2002). Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. NATURE MEDICINE, 8(9), 1024–32. -
CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation
Oh, J. W., Seroogy, C. M., Meyer, E. H., Akbari, O., Berry, G., Fathman, C. G., … Umetsu, D. T. (2002). CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 110(3), 460–68. -
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
Akbari, O., Stock, P., Meyer, E., Kronenberg, M., Sidobre, S., Nakayama, T., … Umetsu, D. T. (2003). Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. NATURE MEDICINE, 9(5), 582–88. -
Adaptation at specific loci. VII. Natural selection, dispersal and the diversity of molecular-functional variation patterns among butterfly species complexes (Colias : Lepidoptera, Pieridae)
Watt, W. B., Wheat, C. W., Meyer, E. H., & Martin, J. F. (2003). Adaptation at specific loci. VII. Natural selection, dispersal and the diversity of molecular-functional variation patterns among butterfly species complexes (Colias : Lepidoptera, Pieridae). MOLECULAR ECOLOGY, 12(5), 1265–1275. -
Glycolipid activation of invariant T cell receptor(+) NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4(+) T cells
Meyer, E. H., Goya, S., Akbari, O., Berry, G. J., Savage, P. B., Kronenberg, M., … Umetsu, D. T. (2006). Glycolipid activation of invariant T cell receptor(+) NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4(+) T cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(8), 2782–87. -
Medicine on a need-to-know basis
Busch, R., Byrne, B., Gandrud, L., Sears, D., Meyer, E., Kattah, M., … Mellins, E. D. (2006). Medicine on a need-to-know basis. NATURE IMMUNOLOGY, 7(6), 543–47. -
Delirium following abrupt discontinuation of fluoxetine
Blum, D., Maldonado, J., Meyer, E., & Lansberg, M. (2008). Delirium following abrupt discontinuation of fluoxetine. CLINICAL NEUROLOGY AND NEUROSURGERY, 110(1), 69–70. -
T cells and NKT cells in the pathogenesis of asthma
Meyer, E. H., DeKruyff, R. H., & Umetsu, D. T. (2008). T cells and NKT cells in the pathogenesis of asthma. ANNUAL REVIEW OF MEDICINE, 59, 281–92. -
Apoptotic Cells Activate NKT Cells through T Cell Ig-Like Mucin-Like-1 Resulting in Airway Hyperreactivity
Lee, H.-H., Meyer, E. H., Goya, S., Pichavant, M., Kim, H. Y., Bu, X., … Umetsu, D. T. (2010). Apoptotic Cells Activate NKT Cells through T Cell Ig-Like Mucin-Like-1 Resulting in Airway Hyperreactivity. JOURNAL OF IMMUNOLOGY, 185(9), 5225–35. -
A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease.
Meyer, E. H., Hsu, A. R., Liliental, J., Löhr, A., Florek, M., Zehnder, J. L., … Negrin, R. S. (2013). A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease. Blood, 121(24), 4955–62. -
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
Pichavant, M., Goya, S., Meyer, E., Johnston, R., Kim, H., Matangkasombut, P., … Umetsu, D. (2008). Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. Presented at the 8th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, BOSTON,MA: ACADEMIC PRESS INC ELSEVIER SCIENCE. -
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
Pichavant, M., Goya, S., Meyer, E. H., Johnston, R. A., Kim, H. Y., Matangkasombut, P., … Umetsu, D. T. (2008). Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. JOURNAL OF EXPERIMENTAL MEDICINE, 205(2), 385–393. -
INKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity
Meyer, E. H., Wurbel, M.-A., Staton, T. L., Pichavant, M., Kan, M. J., Savage, P. B., … Umetsu, D. T. (2007). INKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. JOURNAL OF IMMUNOLOGY, 179(7), 4661–71. -
Glycolipid mediated activation of iNKT cells is sufficient to induce airway hyperreactivity independent of conventional CD4 T cells.
Meyer, E. H., Akbari, O., Berry, G., Savage, P., DeKruyff, R. H., & Umetsu, D. T. (2005). Glycolipid mediated activation of iNKT cells is sufficient to induce airway hyperreactivity independent of conventional CD4 T cells. Presented at the 5th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, BOSTON,MA: ACADEMIC PRESS INC ELSEVIER SCIENCE. -
iNKT-Cells require CCR4 binding of CCL17 to localize to the airways where they are necessary and sufficient for inducing airway hyperreactivity.
Meyer, E., Wurbel, M.-A., Staton, T., Savage, P., DeKruyff, R., Campbell, J., … Umetsu, D. (2006). iNKT-Cells require CCR4 binding of CCL17 to localize to the airways where they are necessary and sufficient for inducing airway hyperreactivity. Presented at the 6th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, SAN FRANCISCO,CA,CA,CA,CA,CA,CA: ACADEMIC PRESS INC ELSEVIER SCIENCE. -
ICOS/ICOSL interaction is required for CD4(+) invariant NKT cell function and homeostatic survival
Akbari, O., Stock, P., Meyer, E. H., Freeman, G. J., Sharpe, A. H., Umetsu, D. T., & DeKruyff, R. H. (2008). ICOS/ICOSL interaction is required for CD4(+) invariant NKT cell function and homeostatic survival. JOURNAL OF IMMUNOLOGY, 180(8), 5448–5456. -
Natural killer T cells regulate the development of asthma
Umetsu, D. T., Meyer, E. H., & DeKruyff, R. H. (2007). Natural killer T cells regulate the development of asthma. INTERNATIONAL REVIEWS OF IMMUNOLOGY, 26(1-2), 121–140. -
Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta(2)-microglobulin-deficient mice
Koh, Y. I., Kim, H. Y., Meyer, E. H., Pichavant, M., Akbari, O., Yasumi, T., … Umetsu, D. T. (2008). Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta(2)-microglobulin-deficient mice. JOURNAL OF IMMUNOLOGY, 181(7), 4560–4569. -
iNKT cells in allergic disease
Meyer, E. H., DeKruyff, R. H., & Umetsu, D. T. (2007). iNKT cells in allergic disease. T CELL ACTIVATION BY CD1 AND LIPID ANTIGENS, 314, 269–291. -
CD1d restricted natural killer T cells are not required for allergic skin inflammation
Elkhal, A., Pichavant, M., He, R., Scott, J., Meyer, E., Goya, S., … Umetsu, D. T. (2006). CD1d restricted natural killer T cells are not required for allergic skin inflammation. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 118(6), 1363–1368. -
Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida, P. E., Meyer, E. H., Kooreman, N. G., Diecke, S., Dey, D., Sanchez-Freire, V., … Wu, J. C. (2014). Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance. Nature Communications, 5, 3903-? -
Memory regulatory T cells reside in human skin
Rodriguez, R. S., Pauli, M. L., Neuhaus, I. M., Yu, S. S., Arron, S. T., Harris, H. W., … Rosenblum, M. D. (2014). Memory regulatory T cells reside in human skin. JOURNAL OF CLINICAL INVESTIGATION, 124(3), 1027–36. -
Prevalence of graft versus host disease and cytomegalovirus infection in patients post-haematopoietic cell transplantation presenting with gastrointestinal symptoms.
Liu, A., Meyer, E., Johnston, L., Brown, J., & Gerson, L. B. (2013). Prevalence of graft versus host disease and cytomegalovirus infection in patients post-haematopoietic cell transplantation presenting with gastrointestinal symptoms. Alimentary Pharmacology & Therapeutics, 38(8), 955–66. -
CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells
Schneidawind, D., Pierini, A., Alvarez, M., Pan, Y., Baker, J., Buechele, C., … Negrin, R. S. (2014). CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells. BLOOD. -
CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells.
Schneidawind, D., Pierini, A., Alvarez, M., Pan, Y., Baker, J., Buechele, C., … Negrin, R. S. (2014). CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells. Blood, 124(22), 3320–28. -
Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models
Florek, M., Sega, E. I., Leveson-Gower, D. B., Baker, J., Mueller, A. M. S., Schneidawind, D., … Negrin, R. S. (2014). Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models. BLOOD, 124(11), 1832–42. -
Third-party CD4(+) invariant natural killer T cells protect from murine GVHD lethality
Schneidawind, D., Baker, J., Pierini, A., Buechele, C., Luong, R. H., Meyer, E. H., & Negrin, R. S. (2015). Third-party CD4(+) invariant natural killer T cells protect from murine GVHD lethality. BLOOD, 125(22), 3491–3500. -
Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy.
Nakasone, H., Remberger, M., Tian, L., Brodin, P., Sahaf, B., Wu, F., … Meyer, E. (2015). Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy. Haematologica, 100(11), 1477–85. -
Freeze and Thaw of CD4(+) CD25(+) Foxp3(+) Regulatory T Cells Results in Loss of CD62L Expression and a Reduced Capacity to Protect against Graft-versus-Host Disease
Florek, M., Schneidawind, D., Pierini, A., Baker, J., Armstrong, R., Pan, Y., … Meyer, E. (2015). Freeze and Thaw of CD4(+) CD25(+) Foxp3(+) Regulatory T Cells Results in Loss of CD62L Expression and a Reduced Capacity to Protect against Graft-versus-Host Disease. PLOS ONE, 10(12). -
TNF-a priming enhances CD4+FoxP3+ regulatory T-cell suppressive function in murine GVHD prevention and treatment.
Pierini, A., Strober, W., Moffett, C., Baker, J., Nishikii, H., Alvarez, M., … Negrin, R. S. (2016). TNF-a priming enhances CD4+FoxP3+ regulatory T-cell suppressive function in murine GVHD prevention and treatment. Blood, 128(6), 866–71. -
A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease
Meyer, E. H., Hsu, A. R., Liliental, J., Loehr, A., Florek, M., Zehnder, J. L., … Negrin, R. S. (2013). A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease. BLOOD, 121(24), 4955–62. -
Methodologic Considerations in the Application of Next-Generation Sequencing of Human TRB Repertoires for Clinical Use
Xu, L., You, X., Zheng, P., Zhang, B. M., Gupta, P. K., Lavori, P., … Zehnder, J. L. (2017). Methodologic Considerations in the Application of Next-Generation Sequencing of Human TRB Repertoires for Clinical Use. JOURNAL OF MOLECULAR DIAGNOSTICS, 19(1), 72–83. -
T cells expressing chimeric antigen receptor promote immune tolerance.
Pierini, A., Iliopoulou, B. P., Peiris, H., Pérez-Cruz, M., Baker, J., Hsu, K., … Meyer, E. H. (2017). T cells expressing chimeric antigen receptor promote immune tolerance. JCI Insight, 2(20). -
HLA-mismatched unrelated donor transplantation using TLI-ATG conditioning has a low risk of GVHD and potent antitumor activity.
Spinner, M. A., Fernández-Viña, M., Creary, L. E., Quinn, O., Elder, L., Arai, S., … Rezvani, A. R. (2017). HLA-mismatched unrelated donor transplantation using TLI-ATG conditioning has a low risk of GVHD and potent antitumor activity. Blood Advances, 1(17), 1347–57. -
Long-Term Outcomes of AML Patients Using Total Lymphoid Irradiation with Anti-Thymocyte Globulin
Nakasone, H., Miklos, D. B., Meyer, E., Rezvani, A., Muffly, L., Weng, W.-K., … Lowsky, R. (2016). Long-Term Outcomes of AML Patients Using Total Lymphoid Irradiation with Anti-Thymocyte Globulin. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Donor-Derived CIK Cell Infusion As Consolidative Therapy after Non-Myeloablative Allogeneic Transplant in Patients with Myeloid Neoplasms
Narayan, R., Benjamin, J., Laport, G., Tian, L., Tate, K., Elder, L., … Meyer, E. (2015). Donor-Derived CIK Cell Infusion As Consolidative Therapy after Non-Myeloablative Allogeneic Transplant in Patients with Myeloid Neoplasms. BLOOD. AMER SOC HEMATOLOGY. -
Infusion of donor-derived CD8(+) memory T cells for relapse following allogeneic hematopoietic cell transplantation
Muffly, L., Sheehan, K., Armstrong, R., Jensen, K., Tate, K., Rezvani, A. R., … Lowsky, R. (2018). Infusion of donor-derived CD8(+) memory T cells for relapse following allogeneic hematopoietic cell transplantation. BLOOD ADVANCES, 2(6), 681–90. -
Phase I/II Clinical Trial of CpG-Activated Whole Cell Vaccine in Mantle Cell Lymphoma (MCL): Results in Safety and Efficacy from Planned Interim Analysis
Chu, M. P., Brody, J., Kohrt, H. E., Frank, M. J., Khodadoust, M., Reddy, S., … Levy, R. (2015). Phase I/II Clinical Trial of CpG-Activated Whole Cell Vaccine in Mantle Cell Lymphoma (MCL): Results in Safety and Efficacy from Planned Interim Analysis. BLOOD. AMER SOC HEMATOLOGY. -
Deep profiling of single T cell receptor repertoire and phenotype with targeted RNA-seq
Ji, X., Lyu, S.-C., Spindler, M., Bacchetta, R., Goncharov, I., Han, A., … Maecker, H. (2015). Deep profiling of single T cell receptor repertoire and phenotype with targeted RNA-seq. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
IL-2 Plus IL-15 Leads to Enhanced Ex Vivo Expansion of Human Invariant Natural Killer T Cells
Mayers, M., Simonetta, F., Lee, A. W., Hirai, T., Maas-Bauer, K., Alvarez, M., … Negrin, R. S. (2018). IL-2 Plus IL-15 Leads to Enhanced Ex Vivo Expansion of Human Invariant Natural Killer T Cells. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Bone Morphogenetic Protein Signaling Pathway Modulation by Blocking Anti-Repulsive Guidance Molecule B Antibody Promotes Tolerance in Graft-Versus-Host Disease
Cruz, M. P., Hsu, K., Iliopoulou, B. P., Erkers, T., Pang, W., Dekruyff, R. H., … Meyer, E. (2018). Bone Morphogenetic Protein Signaling Pathway Modulation by Blocking Anti-Repulsive Guidance Molecule B Antibody Promotes Tolerance in Graft-Versus-Host Disease. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 24(3), S324. -
Quantifying genetic susceptibility in T1DM-implications for diagnosis after age 30
Meyer, E., & Maahs, D. M. (2018). Quantifying genetic susceptibility in T1DM-implications for diagnosis after age 30. NATURE REVIEWS ENDOCRINOLOGY, 14(3), 134–35. -
Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients
Zeiser, R., Burchert, A., Lengerke, C., Verbeek, M., Maas-Bauer, K., Metzelder, S., … von Bubnoff, N. (2015). Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients. BLOOD. AMER SOC HEMATOLOGY. -
TNF-Alpha Priming Enhances CD4(+) FoxP3(+) Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment
Pierini, A., Moffett, C., Schneidawind, D., Baker, J., Nishikii, H., Pan, Y., … Negrin, R. (2015). TNF-Alpha Priming Enhances CD4(+) FoxP3(+) Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment. BLOOD. AMER SOC HEMATOLOGY. -
Loss of CD62L Expression in CD4+FoxP3+Regulatory T Cells Following Freeze-and-Thaw Prevents Protection Against GVHD in Murine Models
Florek, M., Schneidawind, D., Baker, J., Pierini, A., Leveson-Gower, D. B., Pan, Y., … Meyer, E. H. (2014). Loss of CD62L Expression in CD4+FoxP3+Regulatory T Cells Following Freeze-and-Thaw Prevents Protection Against GVHD in Murine Models. BLOOD. AMER SOC HEMATOLOGY. -
Third Party Invariant Natural Killer T Cells Protect from Lethal Graft-Versus-Host Disease through Donor CD4+CD25+FoxP3+Regulatory T Cells
Schneidawind, D., Pierini, A., Baker, J., Buechele, C., Luong, R., Meyer, E., & Negrin, R. (2015). Third Party Invariant Natural Killer T Cells Protect from Lethal Graft-Versus-Host Disease through Donor CD4+CD25+FoxP3+Regulatory T Cells. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
TNF-Alpha Priming Enhances CD4+FoxP3+Regulatory T Cell Suppressive Function in GVHD Prevention and Treatment
Pierini, A., Strober, W. A., Moffett, C., Baker, J., Nishikii, H., Pan, Y., … Negrin, R. (2016). TNF-Alpha Priming Enhances CD4+FoxP3+Regulatory T Cell Suppressive Function in GVHD Prevention and Treatment. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Guide T Cell and Treg Homing for GvHD Control and Tissue Tolerance in Murine Models
Pierini, A., Iliopoulou, B. P., Baker, J., Peiris, H., Hsu, K., Kim, S., … Meyer, E. (2016). The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Guide T Cell and Treg Homing for GvHD Control and Tissue Tolerance in Murine Models. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Increased Activity in the T Cell Effector Phase and Enhanced T Cell Repertoire Target-Tissue Stability Distinguish Alloreactivity Across Major Versus Minor Histocompatibility Barriers
Zheng, P., Vasey, A. E., Baker, J., Iliopoulou, B., Leveson-Gower, D. B., Pierini, A., … Meyer, E. (2015). Increased Activity in the T Cell Effector Phase and Enhanced T Cell Repertoire Target-Tissue Stability Distinguish Alloreactivity Across Major Versus Minor Histocompatibility Barriers. BLOOD. AMER SOC HEMATOLOGY. -
CD4(+) Invariant Natural Killer T Cells Protect from Acute Graft-Versus-Host Disease Lethality through a Dramatic Expansion of Donor-Derived CD4(+)FoxP3(+) Regulatory T Cells
Schneidawind, D., Pierini, A., Alvarez, M., Pan, Y., Baker, J., Kim, B. S., … Negrin, R. (2014). CD4(+) Invariant Natural Killer T Cells Protect from Acute Graft-Versus-Host Disease Lethality through a Dramatic Expansion of Donor-Derived CD4(+)FoxP3(+) Regulatory T Cells. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Outcome of Tandem Autologous/Allogeneic Hematopoietic Cell Transplantation in High-Risk Non Hodgkin's Lymphoma Patients: Stanford University Experience
Wudhikarn, K., Lavori, P., Arai, S., Johnston, L., Laport, G. G., Lowsky, R., … Weng, W.-K. (2014). Outcome of Tandem Autologous/Allogeneic Hematopoietic Cell Transplantation in High-Risk Non Hodgkin's Lymphoma Patients: Stanford University Experience. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Validation of the Hematopoietic Cell Transplantation-Specific Comorbidity Index in Nonmyeloablative Allogeneic Stem Cell Transplantation
Veeraputhiran, M., Yang, L., Sundaram, V., Arai, S., Lowsky, R., Miklos, D., … Johnston, L. (2017). Validation of the Hematopoietic Cell Transplantation-Specific Comorbidity Index in Nonmyeloablative Allogeneic Stem Cell Transplantation. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 23(10), 1744–48. -
Risks and Benefits of Sex-Mismatched Hematopoietic Cell Transplantation Differ By Conditioning Intensity
Nakasone, H., Remberger, M., Tian, L., Brodin, P., Sahaf, B., Wu, F., … Meyer, E. (2014). Risks and Benefits of Sex-Mismatched Hematopoietic Cell Transplantation Differ By Conditioning Intensity. BLOOD. AMER SOC HEMATOLOGY. -
Third Party Invariant Natural Killer T Cells Protect from Graft-Versus-Host Disease Lethality through Expansion of Donor CD4(+)FoxP3(+) Regulatory T Cells
Schneidawind, D., Baker, J., Buechele, C., Meyer, E. H., & Negrin, R. S. (2014). Third Party Invariant Natural Killer T Cells Protect from Graft-Versus-Host Disease Lethality through Expansion of Donor CD4(+)FoxP3(+) Regulatory T Cells. BLOOD. AMER SOC HEMATOLOGY. -
Risks and Benefits of Sex-Mismatched Hematopoietic Cell Transplantation Differ By Conditioning Strategy
Nakasone, H., Remberger, M., Tian, L., Brodin, P., Sahaf, B., Wu, F., … Meyer, E. (2015). Risks and Benefits of Sex-Mismatched Hematopoietic Cell Transplantation Differ By Conditioning Strategy. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
ASBMT Practice Guidelines Committee Survey on Long-Term Follow-Up Clinics for Hematopoietic Cell Transplant Survivors
Hashmi, S. K., Lee, S. J., Savani, B. N., Burns, L., Wingard, J. R., Perales, M.-A., … Carpenter, P. A. (2018). ASBMT Practice Guidelines Committee Survey on Long-Term Follow-Up Clinics for Hematopoietic Cell Transplant Survivors. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 24(6), 1119–24. -
Use of High-Throughput Sequencing (HTS) of TCR beta to Determine the Kinetics of Graft-Versus-Lymphoma (GVL) Effect and T-Cell Repertoire Profiles after Allogeneic Transplant
Weng, W.-K., Armstrong, R., Arai, S., Hoppe, R. T., Meyer, E. H., & Kim, Y. H. (2014). Use of High-Throughput Sequencing (HTS) of TCR beta to Determine the Kinetics of Graft-Versus-Lymphoma (GVL) Effect and T-Cell Repertoire Profiles after Allogeneic Transplant. BLOOD. AMER SOC HEMATOLOGY. -
Allogeneic Transplants from HLA-Mismatched Unrelated Donors Using Total Lymphoid Irradiation and Antithymocyte Globulin Conditioning Retain a Low Risk of Graft-Versus-Host Disease and Non-Relapse Mortality with at Least As Potent Anti-Tumor Activity As with Matched Unrelated Donors
Spinner, M. A., Vina, M. F., Elder, L., Arai, S., Johnston, L., Meyer, E., … Rezvani, A. R. (2016). Allogeneic Transplants from HLA-Mismatched Unrelated Donors Using Total Lymphoid Irradiation and Antithymocyte Globulin Conditioning Retain a Low Risk of Graft-Versus-Host Disease and Non-Relapse Mortality with at Least As Potent Anti-Tumor Activity As with Matched Unrelated Donors. BLOOD. AMER SOC HEMATOLOGY. -
Phase I Study of CD8 Memory T-Cell Donor Lymphocyte Infusion for Relapse of Hematologic Malignancies Following Matched Related Donor Allogeneic Hematopoietic Cell Transplantation
Muffly, L. S., Sheehan, K., Armstrong, R., Tate, K., Tudisco, C., Rezvani, A. R., … Lowsky, R. (2016). Phase I Study of CD8 Memory T-Cell Donor Lymphocyte Infusion for Relapse of Hematologic Malignancies Following Matched Related Donor Allogeneic Hematopoietic Cell Transplantation. BLOOD. AMER SOC HEMATOLOGY. -
Relationship Between Mixed Chimerism and Acceptance of HLA-matched and -Mismatched Kidney Transplants after Withdrawal of Immunosuppressive Drugs
Busque, S., Scandling, J., Lowsky, R., Shizuru, J., Jensen, K., Shori, A., … Strober, S. (2018). Relationship Between Mixed Chimerism and Acceptance of HLA-matched and -Mismatched Kidney Transplants after Withdrawal of Immunosuppressive Drugs. TRANSPLANTATION. LIPPINCOTT WILLIAMS & WILKINS. -
A Proinflammatory Invariant Natural Killer T Cells Phenotypic State Associates with Human Graft-Versus-Host Disease Onset and Response
Erkers, T., Xei, B., Kenyon, L., Rieck, M., Basina, M., Jensen, K., … Meyer, E. H. (2018). A Proinflammatory Invariant Natural Killer T Cells Phenotypic State Associates with Human Graft-Versus-Host Disease Onset and Response. BLOOD, 132. -
The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Facilitate Conventional T Cell and Treg Control of GvHD and Tissue Tolerance in Murine Models
Pierini, A., Iliopoulou, B., Peiris, H., Cruz, M. P., Baker, J., Hsu, K., … Meyer, E. (2016). The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Facilitate Conventional T Cell and Treg Control of GvHD and Tissue Tolerance in Murine Models. BLOOD. AMER SOC HEMATOLOGY. -
A Phase I Study of Donor Regulatory T Cells As Treatment for Steroid Dependent/Refractory Chronic Graft Versus Host Disease
Johnston, L., Armstrong, R., Baker, J., Sahaf, B., Otani, J., Tate, K., … Negrin, R. S. (2016). A Phase I Study of Donor Regulatory T Cells As Treatment for Steroid Dependent/Refractory Chronic Graft Versus Host Disease. BLOOD. AMER SOC HEMATOLOGY. -
Yield of Single versus Upper and Lower Endoscopic Biopsies in the Diagnosis of Gastrointestinal Graft-Versus-Host Disease in Patients with Prior Allogeneic Hematopoietic Stem Cell Transplantation
Liu, A., Meyer, E., Johnston, L., & Gerson, L. (2012). Yield of Single versus Upper and Lower Endoscopic Biopsies in the Diagnosis of Gastrointestinal Graft-Versus-Host Disease in Patients with Prior Allogeneic Hematopoietic Stem Cell Transplantation. AMERICAN JOURNAL OF GASTROENTEROLOGY. NATURE PUBLISHING GROUP. -
Donor-derived CIK Cell Infusion as Consolidation after Non-myeloablative Allogeneic Transplant for Myeloid Neoplasms.
Narayan, R., Benjamin, J. E., Shah, O., Tian, L., Tate, K., Armstrong, R., … Meyer, E. H. (2019). Donor-derived CIK Cell Infusion as Consolidation after Non-myeloablative Allogeneic Transplant for Myeloid Neoplasms. Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. -
CMV after transplant: T-cell repertoire crooks.
Meyer, E. (2015). CMV after transplant: T-cell repertoire crooks. Blood, 125(25), 3827–8. -
Transplantation of donor grafts with defined ratio of conventional and regulatory T cells in HLA-matched recipients.
Meyer, E. H., Laport, G., Xie, B. J., MacDonald, K., Heydari, K., Sahaf, B., … Negrin, R. S. (2019). Transplantation of donor grafts with defined ratio of conventional and regulatory T cells in HLA-matched recipients. JCI Insight, 4(10). -
Transplantation of donor grafts with defined ratio of conventional and regulatory T cells in HLA-matched recipients
Meyer, E. H., Laport, G., Xie, B. J., MacDonald, K., Heydari, K., Sahaf, B., … Negrin, R. S. (2019). Transplantation of donor grafts with defined ratio of conventional and regulatory T cells in HLA-matched recipients. JCI INSIGHT, 4(10). -
Validation of the hematopoietic cell transplantation-specific comorbidity index in non-myeloablative allogeneic stem cell transplantation.
Veeraputhiran, M., Arai, S., Lowsky, R., Miklos, D. B., Meyer, E., Muffly, L. S., … Johnston, L. J. (2016). Validation of the hematopoietic cell transplantation-specific comorbidity index in non-myeloablative allogeneic stem cell transplantation. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin.
Narayan, R., Olsson, N., Wagar, L. E., Medeiros, B. C., Meyer, E., Czerwinski, D., … Levy, R. (2019). Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin. PloS One, 14(7), e0219547. -
Long-term outcomes of high-dose melphalan and carmustine followed by autologous hematopoietic cell transplantation for multiple myeloma.
Neppalli, A. K., Shizuru, J., Johnston, L. J., Muffly, L. S., Weng, W.-K., Negrin, R., … Rezvani, A. R. (2016). Long-term outcomes of high-dose melphalan and carmustine followed by autologous hematopoietic cell transplantation for multiple myeloma. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy.
Hartmann, F. J., Babdor, J., Gherardini, P. F., Amir, E.-A. D., Jones, K., Sahaf, B., … Bendall, S. C. (2019). Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. Cell Reports, 28(3), 819. -
Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform.
Xu, L., Durruthy-Durruthy, R., Eastburn, D. J., Pellegrino, M., Shah, O., Meyer, E., & Zehnder, J. (2019). Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform. Scientific Reports, 9(1), 11119. -
Donor-Derived Cytokine-Induced Killer Cell Infusion as Consolidation after Nonmyeloablative Allogeneic Transplantation for Myeloid Neoplasms
Narayan, R., Benjamin, J. E., Shah, O., Tian, L., Tate, K., Armstrong, R., … Meyer, E. H. (2019). Donor-Derived Cytokine-Induced Killer Cell Infusion as Consolidation after Nonmyeloablative Allogeneic Transplantation for Myeloid Neoplasms. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 25(7), 1293–1303. -
Nonmyeloablative TLI-ATG conditioning for allogeneic transplantation: mature follow-up from a large single-center cohort.
Spinner, M. A., Kennedy, V. E., Tamaresis, J. S., Lavori, P. W., Arai, S., Johnston, L. J., … Lowsky, R. (2019). Nonmyeloablative TLI-ATG conditioning for allogeneic transplantation: mature follow-up from a large single-center cohort. Blood Advances, 3(16), 2454–64. -
Optimization and characterization of calcium phosphate transfection in mesenchymal stem cells.
Lo, C.-W. W., Lin, T.-H. H., Ueno, M., Romero-Lopez, M., Maruyama, M., Kohno, Y., … Goodman, S. B. (2019). Optimization and characterization of calcium phosphate transfection in mesenchymal stem cells. Tissue Engineering. Part C, Methods. -
Blockade of TIM-1 on the donor graft ameliorates graft-versus-host disease following hematopoietic cell transplantation.
Iliopoulou, B. P., Hsu, K., Pérez-Cruz, M., Tang, S.-W. W., Pang, W. W., Erkers, T., … Meyer, E. H. (2019). Blockade of TIM-1 on the donor graft ameliorates graft-versus-host disease following hematopoietic cell transplantation. Blood Advances, 3(21), 3419–31. -
High-Parametric Evaluation of Human Invariant Natural Killer T Cells to Delineate Heterogeneity in Allo- and Autoimmunity.
Erkers, T., Xie, B., Kenyon, L. J., Smith, B., Rieck, M., Jensen, K. P., … Meyer, E. (2020). High-Parametric Evaluation of Human Invariant Natural Killer T Cells to Delineate Heterogeneity in Allo- and Autoimmunity. Blood. -
Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal.
Busque, S., Scandling, J. D., Lowsky, R., Shizuru, J., Jensen, K., Waters, J., … Strober, S. (2020). Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal. Science Translational Medicine, 12(528). -
Analysis of Whole CDR3 TCR Repertoire after Hematopoietic Stem Cell Transplantation in Two Clinical Cohorts.
Shah, O., Tamaresis, J. S., Kenyon, L. J., Xu, L., Zheng, P., Gupta, P., … Meyer, E. H. (2020). Analysis of Whole CDR3 TCR Repertoire after Hematopoietic Stem Cell Transplantation in Two Clinical Cohorts. Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. -
Microtransplantation in Older Patients with AML: A Pilot Study of Safety, Efficacy and Immunologic Effects.
Sung, A. D., Jauhari, S., Siamakpour-Reihani, S., Rao, A. V., Staats, J., Chan, C., … Rizzieri, D. A. (2020). Microtransplantation in Older Patients with AML: A Pilot Study of Safety, Efficacy and Immunologic Effects. American Journal of Hematology. -
Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia: Significant Increase in Survival in the Post-Targeted Immunotherapy Era
Muffly, L., Arai, S., Johnston, L., Lowsky, R., Meyer, E. H., Miklos, D. B., … Cunanan, K. (2020). Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia: Significant Increase in Survival in the Post-Targeted Immunotherapy Era. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
A novel antibody-cell conjugation method to enhance and characterize cytokine-induced killer cells.
Frank, M. J., Olsson, N., Huang, A., Tang, S.-W. W., Negrin, R. S., Elias, J. E., & Meyer, E. H. (2020). A novel antibody-cell conjugation method to enhance and characterize cytokine-induced killer cells. Cytotherapy, 22(3), 135–43. -
Massively parallel interrogation and mining of natively paired human TCR alpha beta repertoires
Spindler, M. J., Nelson, A. L., Wagner, E. K., Oppermans, N., Bridgeman, J. S., Heather, J. M., … Johnson, D. S. (2020). Massively parallel interrogation and mining of natively paired human TCR alpha beta repertoires. NATURE BIOTECHNOLOGY. -
Editorial: Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation.
Schneidawind, D., & Meyer, E. (2020). Editorial: Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation. Frontiers in Immunology, 11, 523. -
Massively parallel interrogation and mining of natively paired human TCRaß repertoires.
Spindler, M. J., Nelson, A. L., Wagner, E. K., Oppermans, N., Bridgeman, J. S., Heather, J. M., … Johnson, D. S. (2020). Massively parallel interrogation and mining of natively paired human TCRaß repertoires. Nature Biotechnology, 38(5), 609–619. -
Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial.
Frank, M. J., Khodadoust, M. S., Czerwinski, D. K., Haabeth, O. A., Chu, M. P., Miklos, D. B., … Levy, R. (2020). Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial. The Journal of Experimental Medicine, 217(9). -
Editorial: NKT Cells in Cancer Immunotherapy.
Webb, T. J., Yuan, W., Meyer, E., & Dellabona, P. (2020). Editorial: NKT Cells in Cancer Immunotherapy. Frontiers in Immunology, 11, 1314. -
Repertoire of Murine T Cells in Target Tissues of MHC-Matched and -Mismatched Graft-Versus-Host Disease
Zheng, P., You, X., Tamaresis, J., Xu, L., Hsu, K., Than, R., … Meyer, E. (2017). Repertoire of Murine T Cells in Target Tissues of MHC-Matched and -Mismatched Graft-Versus-Host Disease. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Outcomes with autologous stem cell transplant vs. non-transplant therapy in patients 70 years and older with multiple myeloma.
Lemieux, C., Muffly, L. S., Rezvani, A., Lowsky, R., Iberri, D. J., Craig, J. K., … Sidana, S. (2020). Outcomes with autologous stem cell transplant vs. non-transplant therapy in patients 70 years and older with multiple myeloma. Bone Marrow Transplantation. -
Recipient-specific T-cell repertoire reconstitution in the gut following murine hematopoietic cell transplant.
Zheng, P., Tamaresis, J., Thangavelu, G., Xu, L., You, X., Blazar, B. R., … Meyer, E. H. (2020). Recipient-specific T-cell repertoire reconstitution in the gut following murine hematopoietic cell transplant. Blood Advances, 4(17), 4232–43. -
Nonmyeloablative allogeneic transplantation achieves clinical and molecular remission in cutaneous T-cell lymphoma.
Weng, W.-K. K., Arai, S., Rezvani, A., Johnston, L., Lowsky, R., Miklos, D., … Kim, Y. H. (2020). Nonmyeloablative allogeneic transplantation achieves clinical and molecular remission in cutaneous T-cell lymphoma. Blood Advances, 4(18), 4474–82. -
Outcomes with Autologous or Allogeneic Stem Cell Transplantation in Patients with Plasma Cell Leukemia in the Era of Novel Agents.
Lemieux, C., Johnston, L. J., Lowsky, R., Muffly, L. S., Craig, J. K., Shiraz, P., … Sidana, S. (2020). Outcomes with Autologous or Allogeneic Stem Cell Transplantation in Patients with Plasma Cell Leukemia in the Era of Novel Agents. Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. -
Safer HLA mismatch transplantation.
Meyer, E. (2020). Safer HLA mismatch transplantation. Blood, 136(13), 1472–74. -
Alloantigen-specific Tr1 cells designed to prevent GvHD have a distinct molecular identity and suppress through CTLA-4 and PD-1
Cepika, A.-M., Chen, P. P., Uyeda, M. J., Cieniewicz, B., Narula, M., Amaya, L., … Roncarolo, M. G. (2020). Alloantigen-specific Tr1 cells designed to prevent GvHD have a distinct molecular identity and suppress through CTLA-4 and PD-1. ournal for ImmunoTherapy of Cancer. -
Hyaluronan synthesis inhibition impairs antigen presentation and delays transplantation rejection.
Marshall, P. L., Nagy, N., Kaber, G., Barlow, G. L., Ramesh, A., Xie, B. J., … Bollyky, P. L. (2020). Hyaluronan synthesis inhibition impairs antigen presentation and delays transplantation rejection. Matrix Biology : Journal of the International Society for Matrix Biology. -
Improved Outcomes for Relapsed/Refractory Classic Hodgkin Lymphoma Following Autologous Stem Cell Transplantation in the Era of Novel Agents
Sica, R. A., Spinner, M. A., Tamaresis, J. S., Advani, R. H., Johnston, L. J., Lowsky, R., … Arai, S. (2019). Improved Outcomes for Relapsed/Refractory Classic Hodgkin Lymphoma Following Autologous Stem Cell Transplantation in the Era of Novel Agents. BLOOD. AMER SOC HEMATOLOGY. -
Dose-Intense BCNU/Melphalan Regimen Followed By Autologous Hematopoietic Cell Transplantation (AHCT) Results in Prolonged PFS in Myeloma Patients
Gandhi, A., Rezvani, A., Lowsky, R., Johnston, L., Shizuru, J. A., Miklos, D. B., … Weng, W.-K. (2019). Dose-Intense BCNU/Melphalan Regimen Followed By Autologous Hematopoietic Cell Transplantation (AHCT) Results in Prolonged PFS in Myeloma Patients. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
A Proinflammatory Invariant Natural Killer T Cell Phenotypic State Associates with Human Graft-Versus-Host Disease Onset
Xie, B. J., Erkers, T., Kenyon, L., Rieck, M., Basina, M., Jensen, K., … Meyer, E. H. (2019). A Proinflammatory Invariant Natural Killer T Cell Phenotypic State Associates with Human Graft-Versus-Host Disease Onset. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Phase I Trial Using CD19/CD22 Bispecific CAR T Cells in Pediatric and Adult Acute Lymphoblastic Leukemia (ALL)
Schultz, L. M., Muffly, L. S., Spiegel, J. Y., Ramakrishna, S., Hossain, N., Baggott, C., … Davis, K. L. (2019). Phase I Trial Using CD19/CD22 Bispecific CAR T Cells in Pediatric and Adult Acute Lymphoblastic Leukemia (ALL). BLOOD. AMER SOC HEMATOLOGY. -
CD22-Directed CAR T-Cell Therapy Induces Complete Remissions in CD19-Directed CAR-Refractory Large B-Cell Lymphoma.
Baird, J. H., Frank, M. J., Craig, J., Patel, S., Spiegel, J. Y., Sahaf, B., … Muffly, L. (2020). CD22-Directed CAR T-Cell Therapy Induces Complete Remissions in CD19-Directed CAR-Refractory Large B-Cell Lymphoma. Blood. -
Immune reconstitution and infectious complications following axicabtagene ciloleucel therapy for large B-cell lymphoma
Baird, J. H., Epstein, D. J., Tamaresis, J. S., Ehlinger, Z., Spiegel, J. Y., Craig, J., … Sidana, S. (2021). Immune reconstitution and infectious complications following axicabtagene ciloleucel therapy for large B-cell lymphoma. BLOOD ADVANCES, 5(1), 143–55. -
Immune reconstitution and infectious complications following axicabtagene ciloleucel therapy for large B-cell lymphoma.
Baird, J. H., Epstein, D. J., Tamaresis, J. S., Ehlinger, Z., Spiegel, J. Y., Craig, J., … Sidana, S. (2021). Immune reconstitution and infectious complications following axicabtagene ciloleucel therapy for large B-cell lymphoma. Blood Advances, 5(1), 143–155. -
Tregs and Mixed Chimerism as Approaches for Tolerance Induction in Islet Transplantation
Pathak, S., & Meyer, E. H. (2021). Tregs and Mixed Chimerism as Approaches for Tolerance Induction in Islet Transplantation. FRONTIERS IN IMMUNOLOGY, 11. -
Autologous stem cell transplantation versus no transplant in patients above 70 with multiple myeloma.
Lemieux, C., Muffly, L. S., Iberri, D. J., Rezvani, A., Lowsky, R., Frank, M. J., … Sidana, S. (2020). Autologous stem cell transplantation versus no transplant in patients above 70 with multiple myeloma. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Impact of proteasome inhibitor vs. IMiD maintenance therapy on outcomes of patients with high-risk multiple myeloma (HRMM).
Tam, E. L., Iberri, D. J., Liedtke, M., Muffly, L. S., Shiraz, P., Frank, M. J., … Sidana, S. (2020). Impact of proteasome inhibitor vs. IMiD maintenance therapy on outcomes of patients with high-risk multiple myeloma (HRMM). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Tregs and Mixed Chimerism as Approaches for Tolerance Induction in Islet Transplantation.
Pathak, S., & Meyer, E. H. (2020). Tregs and Mixed Chimerism as Approaches for Tolerance Induction in Islet Transplantation. Frontiers in Immunology, 11, 612737. -
Use of Backup Stem Cells for Stem Cell Boost and Second Transplant in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation.
Liang, E. C., Muffly, L. S., Shiraz, P., Shizuru, J. A., Johnston, L., Arai, S., … Sidana, S. (2021). Use of Backup Stem Cells for Stem Cell Boost and Second Transplant in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation. Transplantation and Cellular Therapy. -
Generation of recombinant hyperimmune globulins from diverse B-cell repertoires.
Keating, S. M., Mizrahi, R. A., Adams, M. S., Asensio, M. A., Benzie, E., Carter, K. P., … Johnson, D. S. (2021). Generation of recombinant hyperimmune globulins from diverse B-cell repertoires. Nature Biotechnology. -
Using the binary language of IL-2 to prevent GVHD.
Meyer, E. H. (2021). Using the binary language of IL-2 to prevent GVHD. Blood, 137(16), 2136–37. -
Stem Cell Mobilization in Multiple Myeloma: Comparing Safety and Efficacy of Cyclophosphamide +/- Plerixafor vs. G-CSF +/- Plerixafor in the Lenalidomide Era.
Johnsrud, A., Ladha, A., Muffly, L., Shiraz, P., Goldstein, G., Osgood, V., … Sidana, S. (2021). Stem Cell Mobilization in Multiple Myeloma: Comparing Safety and Efficacy of Cyclophosphamide +/- Plerixafor vs. G-CSF +/- Plerixafor in the Lenalidomide Era. Transplantation and Cellular Therapy. -
Adoptively Transferred, In Vitro-Generated Alloantigen-Specific Type 1 Regulatory T (Tr1) Cells Persist Long-Term In Vivo
Cepika, A.-M., Chen, P. P., Agarwal, R., Saini, G., Louis, D. M., Amaya-Hernandez, L. C., … Roncarolo, M. G. (2021). Adoptively Transferred, In Vitro-Generated Alloantigen-Specific Type 1 Regulatory T (Tr1) Cells Persist Long-Term In Vivo. MOLECULAR THERAPY. CELL PRESS. -
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
Glassman, C. R., Su, L., Majri-Morrison, S. S., Winkelmann, H., Mo, F., Li, P., … Garcia, K. C. (2021). Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist. ELife, 10. -
Outcomes after delayed and second autologous stem cell transplant in patients with relapsed multiple myeloma.
Lemieux, C., Muffly, L. S., Iberri, D. J., Craig, J. K., Johnston, L. J., Lowsky, R., … Sidana, S. (2021). Outcomes after delayed and second autologous stem cell transplant in patients with relapsed multiple myeloma. Bone Marrow Transplantation. -
Inferior Clinical Outcomes in Recipients of Cryopreserved Grafts Following Reduced Intensity Allogeneic Hematopoietic Cell Transplantation: A Single Center Report
Bankova, A., Caveney, J., Ramos, T., Bogeholz, J., Heydari, K., Diaz, N., … Arai, S. (2021). Inferior Clinical Outcomes in Recipients of Cryopreserved Grafts Following Reduced Intensity Allogeneic Hematopoietic Cell Transplantation: A Single Center Report. BONE MARROW TRANSPLANTATION. SPRINGERNATURE. -
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial.
Spiegel, J. Y., Patel, S., Muffly, L., Hossain, N. M., Oak, J., Baird, J. H., … Miklos, D. B. (2021). CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial. Nature Medicine. -
Concordance of peripheral blood and bone marrow measurable residual disease in adult acute lymphoblastic leukemia.
Muffly, L., Sundaram, V., Chen, C., Yurkiewicz, I., Kuo, E., Burnash, S., … Miklos, D. B. (2021). Concordance of peripheral blood and bone marrow measurable residual disease in adult acute lymphoblastic leukemia. Blood Advances, 5(16), 3147–3151. -
Development of immunosuppressive myeloid cells to induce tolerance in solid organ and hematopoietic cell transplant recipients.
Jensen, K. P., Hongo, D., Ji, X., Zheng, P., Pawar, R. D., Wu, H.-H., … Strober, S. (2021). Development of immunosuppressive myeloid cells to induce tolerance in solid organ and hematopoietic cell transplant recipients. Blood Advances. -
Incidence and Risk Factors Associated with Bleeding and Thrombosis Following Chimeric Antigen Receptor T Cell Therapy.
Johnsrud, A. J., Craig, J., Baird, J. H., Spiegel, J. Y., Muffly, L., Zehnder, J. L., … Sidana, S. (2021). Incidence and Risk Factors Associated with Bleeding and Thrombosis Following Chimeric Antigen Receptor T Cell Therapy. Blood Advances. -
Evaluation of Patient Products with Aberrant Cryopreservation Curve
Joaquin, Z., McIntyre, C., Meyer, E., McLeod, M. G., Diaz, N., Amiri, Z., … Prarthna, F. (2021). Evaluation of Patient Products with Aberrant Cryopreservation Curve. TRANSFUSION. WILEY. -
Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients.
Chen, P. P., Cepika, A.-M., Agarwal-Hashmi, R., Saini, G., Uyeda, M. J., Louis, D. M., … Roncarolo, M. G. (2021). Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients. Science Translational Medicine, 13(617), eabf5264. -
Identification of Two Subsets of Murine DC1 Dendritic Cells That Differ by Surface Phenotype, Gene Expression, and Function.
Hongo, D., Zheng, P., Dutt, S., Pawar, R. D., Meyer, E., Engleman, E. G., & Strober, S. (2021). Identification of Two Subsets of Murine DC1 Dendritic Cells That Differ by Surface Phenotype, Gene Expression, and Function. Frontiers in Immunology, 12, 746469. -
Phase 2 study of MGTA-145+plerixafor for rapid and reliable hematopoietic stem cell (HSC) mobilization for autologous transplant in multiple myeloma.
Sidana, S., Bankova, A., Hosoya, H., Muffly, L. S., Kumar, S., Johnston, L. J., … Miklos, D. B. (2021). Phase 2 study of MGTA-145+plerixafor for rapid and reliable hematopoietic stem cell (HSC) mobilization for autologous transplant in multiple myeloma. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Incidence and risk factors associated with bleeding and thrombosis following chimeric antigen receptor T-cell therapy
Johnsrud, A., Craig, J., Baird, J., Spiegel, J., Muffly, L., Zehnder, J., … Sidana, S. (2021). Incidence and risk factors associated with bleeding and thrombosis following chimeric antigen receptor T-cell therapy. BLOOD ADVANCES, 5(21), 4465–4475. -
Real-world Experience of Cryopreserved Allogeneic Hematopoietic Grafts in the COVID-19 Pandemic: A Single Center Report.
Bankova, A. K., Caveney, J., Yao, B., Ramos, T. L., Bogeholz, J., Heydari, K., … Arai, S. (1800). Real-world Experience of Cryopreserved Allogeneic Hematopoietic Grafts in the COVID-19 Pandemic: A Single Center Report. Transplantation and Cellular Therapy. -
Massively parallel phenotyping and clonotyping of single T cells
Johnson, D., Conant, C., Withey, G., Lohr, A., Hsu, A., & Meyer, E. (2013). Massively parallel phenotyping and clonotyping of single T cells. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
Repertoire-wide single-cell linked immunoglobulin DNA libraries
Johnson, D., Conant, C., Withey, G., Lhr, A., Hsu, A., & Meyer, E. (2013). Repertoire-wide single-cell linked immunoglobulin DNA libraries. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia in the Modern Era.
Liang, E. C., Craig, J., Torelli, S., Cunanan, K., Iglesias, M., Arai, S., … Muffly, L. (2022). Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia in the Modern Era. Transplantation and Cellular Therapy. -
Mgta-145+Plerixafor Provides GCSFFree Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study
Sidana, S., Bankova, A. K., Hosoya, H., Kumar, S., Tamaresis, J., Le, A., … Miklos, D. B. (2021). Mgta-145+Plerixafor Provides GCSFFree Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study. BLOOD. AMER SOC HEMATOLOGY. -
Outcomes for Myelofibrosis Patients Following Myeloablative Allogeneic Stem Cell Transplantation Using the Orca-T Graft from HLA-Matched Related and Unrelated Donors
Arpita, G., Moroz, A., Muffly, L., Shiraz, P., Schachter, L., Fernhoff, N. B., … Meyer, E. H. (2021). Outcomes for Myelofibrosis Patients Following Myeloablative Allogeneic Stem Cell Transplantation Using the Orca-T Graft from HLA-Matched Related and Unrelated Donors. BLOOD. AMER SOC HEMATOLOGY. -
CT-524 Orca-T, A Precision Engineered Allograft, Results in High GVHD-Free and Relapse-Free Survival Following Myeloablative Conditioning for Hematological Malignancies.
Meyer, E., Pavlova, A., Gandhi, A., Hoeg, R., Oliai, C., Mehta, R., … Negrin, R. (2022). CT-524 Orca-T, A Precision Engineered Allograft, Results in High GVHD-Free and Relapse-Free Survival Following Myeloablative Conditioning for Hematological Malignancies. Clinical Lymphoma, Myeloma & Leukemia, 22 Suppl 2, S447. -
Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning.
Chang, C. A., Bhagchandani, P., Poyser, J., Velasco, B. J., Zhao, W., Kwon, H.-S., … Kim, S. K. (2022). Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning. Cell Reports, 41(6), 111615. -
Immunoregulatory effects of RGMb in gut inflammation.
Perez-Cruz, M., Iliopoulou, B. P., Hsu, K., Wu, H.-H., Erkers, T., Swaminathan, K., … Meyer, E. (2022). Immunoregulatory effects of RGMb in gut inflammation. Frontiers in Immunology, 13, 960329. -
TIM-1 Blockade of the Donor Graft Provides Protection Against Lethal Gvhd
Iliopoulou, B. P., Hsu, K., Pierini, A., Freeman, G. J., Dekruyff, R. H., & Meyer, E. (2016). TIM-1 Blockade of the Donor Graft Provides Protection Against Lethal Gvhd. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. ELSEVIER SCIENCE INC. -
Achievement of Persistent Mixed Chimerism in Recipients of Matched and Mismatched Living Donor Kidney Transplants in a Tolerance Induction Protocol
Scandling, J., Busque, S., Lowsky, R., Pham, T., Hoppe, R., Jensen, K., … Strober, S. (2022). Achievement of Persistent Mixed Chimerism in Recipients of Matched and Mismatched Living Donor Kidney Transplants in a Tolerance Induction Protocol. TRANSPLANTATION. LIPPINCOTT WILLIAMS & WILKINS. -
Outcomes for Acute Myeloid Leukemia Relapse after Allogeneic Hematopoietic Cell Transplantation Remain Poor in the Modern Era
Philip, S., Lowsky, R., Johnston, L. J., Arai, S., Meyer, E. H., Negrin, R. S., … Agrawal, V. (2022). Outcomes for Acute Myeloid Leukemia Relapse after Allogeneic Hematopoietic Cell Transplantation Remain Poor in the Modern Era. BLOOD. AMER SOC HEMATOLOGY. -
Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease and Toxicity
Oliai, C., Hoeg, R. T., Pavlova, A., Gandhi, A., Muffly, L., Mehta, R. S., … Meyer, E. H. (2022). Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease and Toxicity. BLOOD. AMER SOC HEMATOLOGY. -
Orca-Q Demonstrates Favorable GvHD-and-Relapse-Free Survival in Haploidentical Transplants without Post-Transplant Cyclophosphamide
Salhotra, A., Srour, S. A., Hoeg, R. T., Saad, A., Meyer, E. H., Pavlova, A., … Abedi, M. (2022). Orca-Q Demonstrates Favorable GvHD-and-Relapse-Free Survival in Haploidentical Transplants without Post-Transplant Cyclophosphamide. BLOOD. AMER SOC HEMATOLOGY. -
Orca-T, A Precision Engineered Allograft, Results in High GVHD-Free and Relapse-Free Survival Following Myeloablative Conditioning for Hematological Malignancies
Meyer, E., Pavlova, A., Gandhi, A., Hoeg, R., Oliai, C., Mehta, R., … Negrin, R. (2022). Orca-T, A Precision Engineered Allograft, Results in High GVHD-Free and Relapse-Free Survival Following Myeloablative Conditioning for Hematological Malignancies. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
Analysis of Bendamustine Lymphodepletion, CD19 CART Expansion, Safety and Efficacy in Patients with Rel/Ref NonHodgkin Lymphoma
Bharadwaj, S., Hamilton, M. P., Sahaf, B., Tamaresis, J., Patil, S., Hanson, P. J., … Dahiya, S. (2022). Analysis of Bendamustine Lymphodepletion, CD19 CART Expansion, Safety and Efficacy in Patients with Rel/Ref NonHodgkin Lymphoma. BLOOD. AMER SOC HEMATOLOGY. -
The Development of Carhlh after Axicabtagene Ciloleucel Is Associated with Poor Outcomes
Philip, S., Srinagesh, H. K., Hamilton, M. P., Gentille, C., Mina, A., Arai, S., … Frank, M. J. (2022). The Development of Carhlh after Axicabtagene Ciloleucel Is Associated with Poor Outcomes. BLOOD. AMER SOC HEMATOLOGY. -
Higher Rates of Severe Infection and Persistent Cytopenias in Long-Term CAR19 Responders Than after Autologous HCT: A Single Institution Study of 139 Subjects
Hamilton, M. P., Liu-Fei, F. C., Alig, S. K., Tamaresis, J., Esfahani, M. S., Good, Z., … Alizadeh, A. A. (2022). Higher Rates of Severe Infection and Persistent Cytopenias in Long-Term CAR19 Responders Than after Autologous HCT: A Single Institution Study of 139 Subjects. BLOOD. AMER SOC HEMATOLOGY. -
Rapid Immune Reconstitution and Elevated Regulatory T Cell Frequencies in Patients Treated with Orca-T
Meyer, E. H., Killian, M. S., Pavlova, A., Bader, C., Summers, S., Teque, F., … Fernhoff, N. B. (2022). Rapid Immune Reconstitution and Elevated Regulatory T Cell Frequencies in Patients Treated with Orca-T. BLOOD. AMER SOC HEMATOLOGY. -
HLA Class I genotype is associated with relapse risk after allogeneic stem cell transplantation for NPM1-mutated AML.
Narayan, R., Niroula, A., Wang, T., Kuxhausen, M., He, M., Meyer, E., … Lee, S. J. (2023). HLA Class I genotype is associated with relapse risk after allogeneic stem cell transplantation for NPM1-mutated AML. Transplantation and Cellular Therapy. -
FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.
Martinez, H. A., Koliesnik, I., Kaber, G., Reid, J. K., Nagy, N., Barlow, G., … Kuipers, H. F. (2023). FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues. BioRxiv : the Preprint Server for Biology. -
Orca-Q Demonstrates Favorable Graft-Versus-Host Disease (GvHD) and Relapse-Free Survival With Haploidentical Donors Without Post-Transplant Cyclophosphamide
Srour, S. A., Salhotra, A., Lowsky, R., Hoeg, R. T., Saad, A., Waller, E. K., … Abedi, M. (2023). Orca-Q Demonstrates Favorable Graft-Versus-Host Disease (GvHD) and Relapse-Free Survival With Haploidentical Donors Without Post-Transplant Cyclophosphamide. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease (GvHD) and Toxicity
Salhotra, A., Oliai, C., Hoeg, R. T., Gandhi, A., Muffly, L., Srour, S. A., … Meyer, E. (2023). Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease (GvHD) and Toxicity. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
- Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell
- Delayed Blood Stem Transplantation in HLA Matched Kidney Transplant Recipients to Eliminate Immunosuppressive Drugs.
Practice Locations
Blood and Marrow Transplant Program (BMT) - 900 Blake Wilbur Drive Palo Alto, CA
Palo Alto, CABlood and Marrow Transplant Program (BMT) - 900 Blake Wilbur Drive
900 Blake Wilbur Drive, 2nd Floor
Palo Alto , CA 94304
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Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
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