Biography
Professional Summary
Education & Certifications
- Residency: UCSF Dept of Internal Medicine (2011) CA
- Board Certification: American Board of Internal Medicine, Internal Medicine (2011)
- Fellowship: UCSF Hematology and Medical Oncology Fellowship (2014) CA
- Medical Education: University of California Davis School of Medicine (2008) CA
Administrative Appointments
- Medical Director, Stanford Hospital Inpatient Hematology Service (2021 - Present)
- Member, Stanford Cancer Institute (2019 - Present)
- Panel Member, Acute Leukemia Working Group, Southwest Oncology Group (SWOG) (2019 - Present)
- Panel Member, Acute Myeloid Leukemia Guidelines Committee, National Comprehensive Cancer Network (2019 - Present)
Publications
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How I treat CNS lymphomas
Rubenstein, J. L., Gupta, N. K., Mannis, G. N., LaMarre, A. K., & Treseler, P. (2013). How I treat CNS lymphomas. BLOOD, 122(14), 2318–30. -
Delayed hematopoietic recovery after auto-SCT in patients receiving arsenic trioxide-based therapy for acute promyelocytic leukemia: a multi-center analysis
Mannis, G. N., Logan, A. C., Leavitt, A. D., Yanada, M., Hwang, J., Olin, R. L., … Martin, T. G. (2015). Delayed hematopoietic recovery after auto-SCT in patients receiving arsenic trioxide-based therapy for acute promyelocytic leukemia: a multi-center analysis. BONE MARROW TRANSPLANTATION, 50(1), 40–44. -
The Transfusion Tether: Bridging the Gap Between End-Stage Hematologic Malignancies and Optimal End-of-Life Care.
Mannis, G. N., McNey, L. M., Gupta, N. K., & Gross, D. M. (2016). The Transfusion Tether: Bridging the Gap Between End-Stage Hematologic Malignancies and Optimal End-of-Life Care. American Journal of Hematology. -
Long-term survival in AIDS-related primary central nervous system lymphoma.
Gupta, N. K., Nolan, A., Omuro, A., Reid, E. G., Wang, C.-C. C., Mannis, G., … Rubenstein, J. L. (2016). Long-term survival in AIDS-related primary central nervous system lymphoma. Neuro-Oncology. -
Limitation in Patient-Reported Function Is Associated with Inferior Survival in Older Adults Undergoing Autologous Hematopoietic Cell Transplantation.
Nawas, M. T., Andreadis, C., Martin, T. G., Wolf, J. L., Ai, W. Z., Kaplan, L. D., … Olin, R. L. (2019). Limitation in Patient-Reported Function Is Associated with Inferior Survival in Older Adults Undergoing Autologous Hematopoietic Cell Transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. -
Venetoclax in Combination with Decitabine for Relapsed T-Cell Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Cell Transplant
Rahmat, L. T., Nguyen, A., Abdulhaq, H., Prakash, S., Logan, A. C., & Mannis, G. N. (2018). Venetoclax in Combination with Decitabine for Relapsed T-Cell Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Cell Transplant. CASE REPORTS IN HEMATOLOGY, 6092646. -
Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML
DiNardo, C. D., Stein, E. M., de Botton, S., Roboz, G. J., Altman, J. K., Mims, A. S., … Kantarjian, H. M. (2018). Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML. NEW ENGLAND JOURNAL OF MEDICINE, 378(25), 2386–98. -
Discussion on reply to Foley et al., 'Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation?'
Mannis, G. N. (2018). Discussion on reply to Foley et al., 'Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation?'. CANCER GENETICS, 220, 77–78. -
Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation?
Foley, N., Van Ziffle, J., Yu, J., Qi, Z., Grenert, J. P., Yeh, I., … Mannis, G. N. (2017). Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation? CANCER GENETICS, 216, 74–78. -
Regression of methotrexate-resistant AIDS-related primary central nervous system lymphoma with lenalidomide plus combination anti-retroviral therapy
Gupta, N. K., Wang, C.-C., Mannis, G. N., Yu, J.-P. J., & Rubenstein, J. L. (2017). Regression of methotrexate-resistant AIDS-related primary central nervous system lymphoma with lenalidomide plus combination anti-retroviral therapy. LEUKEMIA & LYMPHOMA, 58(11), 2748–51. -
Multigene Measurable Residual Disease Assessment Improves Acute Myeloid Leukemia Relapse Risk Stratification in Autologous Hematopoietic Cell Transplantation
Mule, M. P., Mannis, G. N., Wood, B. L., Radich, J. R., Hwang, J., Ramos, N. R., … Hourigan, C. S. (2016). Multigene Measurable Residual Disease Assessment Improves Acute Myeloid Leukemia Relapse Risk Stratification in Autologous Hematopoietic Cell Transplantation. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 22(11), 1974–82. -
Paraproteinemic keratopathy as the presenting sign of hematologic malignancy
Mannis, T. E., Mannis, G. N., Waterhouse, E. G., Aldave, A. J., & Rose-Nussbaumer, J. (2016). Paraproteinemic keratopathy as the presenting sign of hematologic malignancy. AMERICAN JOURNAL OF HEMATOLOGY, 91(9), 961–62. -
Long-term outcomes of patients with intermediate-risk acute myeloid leukemia treated with autologous hematopoietic cell transplant in first complete remission
Mannis, G. N., Martin, T. G., Damon, L. E., Logan, A. C., Olin, R. L., Flanders, M. D., … Andreadis, C. (2016). Long-term outcomes of patients with intermediate-risk acute myeloid leukemia treated with autologous hematopoietic cell transplant in first complete remission. LEUKEMIA & LYMPHOMA, 57(7), 1560–66. -
Quantification of Acute Lymphoblastic Leukemia Clonotypes in Leukapheresed Peripheral Blood Progenitor Cells Predicts Relapse Risk after Autologous Hematopoietic Stem Cell Transplantation
Mannis, G. N., Martin, T. G., Damon, L. E., Andreadis, C., Olin, R. L., Kong, K. A., … Logan, A. C. (2016). Quantification of Acute Lymphoblastic Leukemia Clonotypes in Leukapheresed Peripheral Blood Progenitor Cells Predicts Relapse Risk after Autologous Hematopoietic Stem Cell Transplantation. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 22(6), 1030–36. -
Inferior vena cava filter thrombosis
Byrne, M., Mannis, G. N., Nair, J., & Andreadis, C. (2016). Inferior vena cava filter thrombosis. CLINICAL CASE REPORTS, 4(2), 162–64. -
A Phase I Study of Targeted, Dose-Escalated Intravenous Busulfan in Combination With Etoposide as Myeloablative Therapy for Autologous Stem Cell Transplantation in Acute Myeloid Leukemia
Mannis, G. N., Andreadis, C., Logan, A. C., Damon, L. E., Benet, L. Z., Ai, W. Z., … Martin, T. G. (2015). A Phase I Study of Targeted, Dose-Escalated Intravenous Busulfan in Combination With Etoposide as Myeloablative Therapy for Autologous Stem Cell Transplantation in Acute Myeloid Leukemia. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 15(6), 377–83. -
Risk-Reducing Salpingo-oophorectomy and Ovarian Cancer Screening in 1077 Women After BRCA Testing
Mannis, G. N., Fehniger, J. E., Creasman, J. S., Jacoby, V. L., & Beattie, M. S. (2013). Risk-Reducing Salpingo-oophorectomy and Ovarian Cancer Screening in 1077 Women After BRCA Testing. JAMA INTERNAL MEDICINE, 173(2), 96–103. -
Maintenance Lenalidomide in Primary CNS Lymphoma.
Rubenstein, J. L., Geng, H., Vu, K., Mannis, G., Formaker, P., Hwang, J., … Damato, B. (2019). Maintenance Lenalidomide in Primary CNS Lymphoma. Annals of Oncology : Official Journal of the European Society for Medical Oncology. -
Low-dose lenalidomide maintenance after induction therapy in older patients with primary central nervous system lymphoma.
Vu, K., Mannis, G., Hwang, J., Geng, H., & Rubenstein, J. L. (2019). Low-dose lenalidomide maintenance after induction therapy in older patients with primary central nervous system lymphoma. British Journal of Haematology. -
Advance care planning and end-of-life care for patients with hematologic malignancies who die after hematopoietic cell transplant.
Eckhert, E. E., Schoenbeck, K. L., Galligan, D., McNey, L. M., Hwang, J., & Mannis, G. N. (2017). Advance care planning and end-of-life care for patients with hematologic malignancies who die after hematopoietic cell transplant. Bone Marrow Transplantation, 52(6), 929–931. -
Ibrutinib rash in a patient with 17p del chronic lymphocytic leukemia.
Mannis, G., Wu, D., Dea, T., Mauro, T., & Hsu, G. (2015). Ibrutinib rash in a patient with 17p del chronic lymphocytic leukemia. American Journal of Hematology, 90(2), 179. -
Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.
Tallman, M. S., Wang, E. S., Altman, J. K., Appelbaum, F. R., Bhatt, V. R., Bixby, D., … Ogba, N. (2019). Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN, 17(6), 721–49. -
Functional status as measured by geriatric assessment predicts inferior survival in older allogeneic hematopoietic cell transplant recipients.
Huang, L.-W. W., Sheng, Y., Andreadis, C., Logan, A. C., Mannis, G. N., Smith, C. C., … Olin, R. L. (2019). Functional status as measured by geriatric assessment predicts inferior survival in older allogeneic hematopoietic cell transplant recipients. Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. -
Allogeneic HSCT for adult-onset leukoencephalopathy with spheroids and pigmented glia.
Gelfand, J. M., Greenfield, A. L., Barkovich, M., Mendelsohn, B. A., Van Haren, K., Hess, C. P., & Mannis, G. N. (2019). Allogeneic HSCT for adult-onset leukoencephalopathy with spheroids and pigmented glia. Brain : a Journal of Neurology. -
Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
Roboz, G. J., DiNardo, C. D., Stein, E. M., de Botton, S., Mims, A. S., Prince, G. T., … Stone, R. M. (2019). Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia. Blood. -
Hypomethylating agents super-responders: challenging the dogma of long-term remission for acute myeloid leukemia.
Maakaron, J. E., Ozga, M. P., Mannis, G. N., Pulley, W., Foster, M. C., Zeidner, J. F., & Mims, A. S. (2020). Hypomethylating agents super-responders: challenging the dogma of long-term remission for acute myeloid leukemia. Annals of Hematology. -
Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience.
Azizi, A., Ediriwickrema, A., Dutta, R., Patel, S. A., Shomali, W., Medeiros, B., … Zhang, T. (2020). Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience. Leukemia & Lymphoma, 1–8. -
Improved Outcomes of Octogenarians and Nonagenarians with Acute Myeloid Leukemia in the Era of Novel Therapies.
Jeng, M. Y., Dutta, R., Tan, I. T., Zhang, T. Y., & Mannis, G. N. (2020). Improved Outcomes of Octogenarians and Nonagenarians with Acute Myeloid Leukemia in the Era of Novel Therapies. American Journal of Hematology. -
Venetoclax monotherapy for cutaneous blastic plasmacytoid dendritic cell neoplasm.
Schwede, M., Tan, I. T., Atibalentja, D. F., Dickman, M. M., Rieger, K. E., & Mannis, G. N. (2020). Venetoclax monotherapy for cutaneous blastic plasmacytoid dendritic cell neoplasm. Annals of Hematology. -
Hematopoietic Cell Transplantation in the Treatment of Newly Diagnosed Adult Acute Myeloid Leukemia: An Evidence-Based Review from the American Society of Transplantation and Cellular Therapy.
Dholaria, B., Savani, B. N., Hamilton, B. K., Oran, B., Liu, H. D., Tallman, M. S., … Nagler, A. (2020). Hematopoietic Cell Transplantation in the Treatment of Newly Diagnosed Adult Acute Myeloid Leukemia: An Evidence-Based Review from the American Society of Transplantation and Cellular Therapy. Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. -
Hepatic veno-occlusive disease in allogeneic stem cell transplant recipients with prior exposure to gemtuzumab ozogamicin or inotuzumab ozogamicin.
Ladha, A., Mannis, G., & Muffly, L. (2020). Hepatic veno-occlusive disease in allogeneic stem cell transplant recipients with prior exposure to gemtuzumab ozogamicin or inotuzumab ozogamicin. Leukemia & Lymphoma, 1–7. -
Serial comprehensive geriatric and quality of life assessments in adults age = 50 years undergoing autologous hematopoietic cell transplantation.
Nawas, M. T., Sheng, Y., Huang, C.-Y. Y., Andreadis, C., Martin, T. G., Wolf, J. L., … Olin, R. L. (2020). Serial comprehensive geriatric and quality of life assessments in adults age = 50 years undergoing autologous hematopoietic cell transplantation. Journal of Geriatric Oncology. -
NCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021.
Pollyea, D. A., Bixby, D., Perl, A., Bhatt, V. R., Altman, J. K., Appelbaum, F. R., … Tallman, M. S. (2021). NCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021. Journal of the National Comprehensive Cancer Network : JNCCN, 19(1), 16–27. -
Routine use of gemtuzumab ozogamicin in 7?+?3-based inductions for all 'non-adverse' risk AML.
Ladha, A., Hui, G., Cheung, E., Berube, C., Coutre, S. E., Gotlib, J., … Mannis, G. N. (2021). Routine use of gemtuzumab ozogamicin in 7?+?3-based inductions for all 'non-adverse' risk AML. Leukemia & Lymphoma, 1–6. -
Epstein-Barr virus-positive lymphoproliferative disorder manifesting as pulmonary disease in a patient with acute myeloid leukemia: a case report.
Dutta, R., Miao, S. Y., Phan, P., Fernandez-Pol, S., Shiraz, P., Ho, D., … Zhang, T. Y. (2021). Epstein-Barr virus-positive lymphoproliferative disorder manifesting as pulmonary disease in a patient with acute myeloid leukemia: a case report. Journal of Medical Case Reports, 15(1), 170. -
Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis.
Wang, V. E., Blaser, B. W., Patel, R. K., Behbehani, G. K., Rao, A. A., Durbin-Johnson, B., … Andreadis, C. (2021). Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis. Blood Cancer Discovery, 2(5), 434–449. -
The First-in-Class Anti-CD47 Antibody Magrolimab in Combination with Azacitidine Is Well Tolerated and Effective in AML Patients: Phase 1b Results
Sallman, D., Asch, A., Kambhampati, S., Al Malki, M., Zeidner, J., Donnellan, W., … Daver, N. (2021). The First-in-Class Anti-CD47 Antibody Magrolimab in Combination with Azacitidine Is Well Tolerated and Effective in AML Patients: Phase 1b Results. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
Feasibility Study Integrating Electronic Patient-Reported Outcomes (PROs) and Palliative Care for High-Risk Acute Myeloid Leukemia (AML) Patients
Tan, I., Choi, J. H., Cunanan, K., Fronk, J., Zhang, T., Mannis, G. N., & Ramchandran, K. (2021). Feasibility Study Integrating Electronic Patient-Reported Outcomes (PROs) and Palliative Care for High-Risk Acute Myeloid Leukemia (AML) Patients. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
Measurable Residual Disease Status and FLT3 Inhibitor Therapy in Patients with FLT3-ITD-Mutated AML Following Allogeneic Hematopoietic Cell Transplantation
Liang, E. C., Chen, C., Lu, R., Mannis, G. N., & Muffly, L. (2021). Measurable Residual Disease Status and FLT3 Inhibitor Therapy in Patients with FLT3-ITD-Mutated AML Following Allogeneic Hematopoietic Cell Transplantation. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
Measurable residual disease status and FLT3 inhibitor therapy in patients with FLT3-ITD mutated AML following allogeneic hematopoietic cell transplantation.
Liang, E. C., Chen, C., Lu, R., Mannis, G. N., & Muffly, L. (2021). Measurable residual disease status and FLT3 inhibitor therapy in patients with FLT3-ITD mutated AML following allogeneic hematopoietic cell transplantation. Bone Marrow Transplantation. -
Preliminary results of V-FAST, a phase 1b master trial to investigate CPX-351 combined with targeted agents in newly diagnosed AML.
Pullarkat, V., Levis, M. J., Mannis, G. N., Strickland, S. A., Lin, T. L., Faderl, S., … Erba, H. P. (2021). Preliminary results of V-FAST, a phase 1b master trial to investigate CPX-351 combined with targeted agents in newly diagnosed AML. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Event free survival in adults with relapsed ALL who underwent front-line therapy with CALGB 10403.
Raychaudhuri, S., Yurkiewicz, I., Mannis, G. N., Medeiros, B. C., Coutre, S. E., Muffly, L. S., & Liedtke, M. (2021). Event free survival in adults with relapsed ALL who underwent front-line therapy with CALGB 10403. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Heterogeneous Definitions of Secondary Acute Myeloid Leukemia (AML) Yield Distinct Outcomes in Response to First-Line Treatment with Hypomethylating Agents (HMA) and Venetoclax (Ven)
Tan, I., Schwede, M., Phan, P., Yin, R., Zhang, T. Y., & Mannis, G. N. (2021). Heterogeneous Definitions of Secondary Acute Myeloid Leukemia (AML) Yield Distinct Outcomes in Response to First-Line Treatment with Hypomethylating Agents (HMA) and Venetoclax (Ven). -
Gilteritinib Clinical Activity in Relapsed/Refractory FLT3 Mutated AML Previously Treated with FLT3 inhibitors.
Numan, Y., Abdel Rahman, Z., Grenet, J., Boisclair, S., Bewersdorf, J. P., Collins, C., … Altman, J. K. (2022). Gilteritinib Clinical Activity in Relapsed/Refractory FLT3 Mutated AML Previously Treated with FLT3 inhibitors. American Journal of Hematology. -
Characterisation of infections in patients with acute myeloid leukaemia receiving venetoclax and a hypomethylating agent.
On, S., Rath, C. G., Lan, M., Wu, B., Lau, K. M., Cheung, E., … Saunders, I. M. (2022). Characterisation of infections in patients with acute myeloid leukaemia receiving venetoclax and a hypomethylating agent. British Journal of Haematology. -
Patterns and predictors of functional decline after alloHCT in older adults.
Huang, L.-W. W., Sheng, Y., Andreadis, C., Logan, A. C., Mannis, G. N., Smith, C. C., … Olin, R. L. (2022). Patterns and predictors of functional decline after alloHCT in older adults. Transplantation and Cellular Therapy. -
Outcomes of Allogeneic Transplantation after Hypomethylating Agents with Venetoclax in Acute Myeloid Leukemia.
Kennedy, V. E., Hui, G., Azenkot, T., Gaut, D., Wieduwilt, M. J., Oliai, C., … Mannis, G. N. (2022). Outcomes of Allogeneic Transplantation after Hypomethylating Agents with Venetoclax in Acute Myeloid Leukemia. American Journal of Hematology. -
Preliminary Results By Age Group of Treatment with CPX-351 Plus Venetoclax in Adults with Newly Diagnosed AML: Subgroup Analysis of the V-FAST Phase 1b Master Trial
Pullarkat, V. A., Levis, M., Mannis, G. N., Strickland, S. A., Lin, T. L., Faderl, S., … Erba, H. P. (2021). Preliminary Results By Age Group of Treatment with CPX-351 Plus Venetoclax in Adults with Newly Diagnosed AML: Subgroup Analysis of the V-FAST Phase 1b Master Trial. BLOOD. AMER SOC HEMATOLOGY. -
AML-464 Tolerability and Efficacy of the First-In-Class Anti-CD47 Antibody Magrolimab Combined With Azacitidine in Frontline Patients With TP53-Mutated Acute Myeloid Leukemia (AML): Phase 1b Results.
Daver, N., Vyas, P., Kambhampati, S., Malki, M. A., Larson, R., Asch, A., … Sallman, D. (2022). AML-464 Tolerability and Efficacy of the First-In-Class Anti-CD47 Antibody Magrolimab Combined With Azacitidine in Frontline Patients With TP53-Mutated Acute Myeloid Leukemia (AML): Phase 1b Results. Clinical Lymphoma, Myeloma & Leukemia, 22 Suppl 2, S253–S254. -
Tolerability and efficacy of the first-in-class anti-CD47 antibody magrolimab combined with azacitidine in frontline TP53m AML patients: Phase 1b results.
Daver, N. G., Vyas, P., Kambhampati, S., Al Malki, M. M., Larson, R. A., Asch, A. S., … Sallman, D. A. (2022). Tolerability and efficacy of the first-in-class anti-CD47 antibody magrolimab combined with azacitidine in frontline TP53m AML patients: Phase 1b results. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Embedded outpatient palliative care for hematologic malignancies: Referral patterns and health care utilization.
Tsang, M., Bischoff, K. E., Schoenbeck, K. L., Berry, K., O'Riordan, D., Fakhri, B., … Rabow, M. W. (2022). Embedded outpatient palliative care for hematologic malignancies: Referral patterns and health care utilization. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
V-FAST master trial: Preliminary results of treatment with CPX-351 plus midostaurin in adults with newly diagnosed FLT3-mutated acute myeloid leukemia.
McCloskey, J. K., Pullarkat, V. A., Mannis, G. N., Lin, T. L., Strickland, S. A., Fathi, A. T., … Levis, M. J. (2022). V-FAST master trial: Preliminary results of treatment with CPX-351 plus midostaurin in adults with newly diagnosed FLT3-mutated acute myeloid leukemia. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: Position on Standards of Care and Areas of Need.
Pemmaraju, N., Kantarjian, H. M., Sweet, K. L., Wang, E. S., Senapati, J., Wilson, N. R., … Lane, A. A. (2022). North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: Position on Standards of Care and Areas of Need. Blood. -
Value of embedded palliative care: outpatient palliative care and healthcare utilization for hematologic malignancies.
Tsang, M., Bischoff, K. E., Schoenbeck, K. L., Berry, K., O'Riordan, D., Fakhri, B., … Rabow, M. (2023). Value of embedded palliative care: outpatient palliative care and healthcare utilization for hematologic malignancies. Blood Advances. -
Outcomes with Molecularly Targeted Agents As Salvage Therapy Following Frontline HMA/Venetoclax in Adults with Acute Myeloid Leukemia: A Multi-Center Retrospective Analysis
Khanna, V., Azenkot, T., Liu, S. (Q., Gilbert, J., Cheung, E., Lau, K., … Mannis, G. N. (2022). Outcomes with Molecularly Targeted Agents As Salvage Therapy Following Frontline HMA/Venetoclax in Adults with Acute Myeloid Leukemia: A Multi-Center Retrospective Analysis. BLOOD. AMER SOC HEMATOLOGY. -
Tolerability and Efficacy of the First-InClass Anti-CD47 Antibody Magrolimab Combined With Azacitidine in Frontline Patients With TP53-Mutated Acute Myeloid Leukemia (AML): Phase 1b Results
Daver, N., Vyas, P., Kambhampati, S., Al Malki, M., Larson, R., Asch, A., … Sallman, D. (2022). Tolerability and Efficacy of the First-InClass Anti-CD47 Antibody Magrolimab Combined With Azacitidine in Frontline Patients With TP53-Mutated Acute Myeloid Leukemia (AML): Phase 1b Results. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
Measurable Residual Disease Conversion Rate with Consolidation Chemotherapy in Acute Myeloid Leukemia
Gaut, D., Oliai, C., Boiarsky, J., Zhang, S., Azenkot, T., Kennedy, V. E., … Schiller, G. J. (2022). Measurable Residual Disease Conversion Rate with Consolidation Chemotherapy in Acute Myeloid Leukemia. BLOOD. AMER SOC HEMATOLOGY. -
V-FAST Master Trial: Subgroup Analysis of Outcomes with CPX-351 Plus Midostaurin in Adults with Newly Diagnosed Acute Myeloid Leukemia By FLT3 Mutation Type
McCloskey, J., Pullarkat, V. A., Mannis, G. N., Lin, T. L., Strickland, S. A., Fathi, A. T., … Levis, M. J. (2022). V-FAST Master Trial: Subgroup Analysis of Outcomes with CPX-351 Plus Midostaurin in Adults with Newly Diagnosed Acute Myeloid Leukemia By FLT3 Mutation Type. BLOOD. AMER SOC HEMATOLOGY. -
The Goldilocks Dilemma in AML: Too Young and Fit, but Not Young and Fit Enough.
St Martin, E. C., Zhang, T. Y., & Mannis, G. N. (2023). The Goldilocks Dilemma in AML: Too Young and Fit, but Not Young and Fit Enough. Clinical Lymphoma, Myeloma & Leukemia. -
Acute Myeloid Leukemia, Version 3.2023, NCCN Clinical Practice Guidelines in Oncology.
Pollyea, D. A., Altman, J. K., Assi, R., Bixby, D., Fathi, A. T., Foran, J. M., … Stehman, K. (2023). Acute Myeloid Leukemia, Version 3.2023, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN, 21(5), 503–513. -
Older Adults With Newly Diagnosed AML: Hot Topics for the Practicing Clinician.
Lai, C., Bhansali, R. S., Kuo, E. J., Mannis, G., & Lin, R. J. (2023). Older Adults With Newly Diagnosed AML: Hot Topics for the Practicing Clinician. American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting, 43, e390018. -
Leukostasis-induced digital ischemia.
Hasty, A., Joshi, M., Lee, D., & Mannis, G. N. (2023). Leukostasis-induced digital ischemia. EJHaem, 4(2), 497–498. -
Outcomes with molecularly targeted agents as salvage therapy following frontline venetoclax + hypomethylating agent in adults with acute myeloid leukemia: A multicenter retrospective analysis.
Khanna, V., Azenkot, T., Liu, S. Q., Gilbert, J., Cheung, E., Lau, K., … Mannis, G. N. (2023). Outcomes with molecularly targeted agents as salvage therapy following frontline venetoclax + hypomethylating agent in adults with acute myeloid leukemia: A multicenter retrospective analysis. Leukemia Research, 131, 107331. -
Standardising acute myeloid leukaemia classification systems: a perspective from a panel of international experts.
Shallis, R. M., Daver, N., Altman, J. K., Komrokji, R. S., Pollyea, D. A., Badar, T., … Zeidan, A. M. (2023). Standardising acute myeloid leukaemia classification systems: a perspective from a panel of international experts. The Lancet. Haematology. -
Association of geriatric measures and global frailty with cognitive decline after allogeneic hematopoietic cell transplantation in older adults.
Huang, L.-W. W., Shi, Y., Andreadis, C., Logan, A. C., Mannis, G. N., Smith, C. C., … Olin, R. L. (2023). Association of geriatric measures and global frailty with cognitive decline after allogeneic hematopoietic cell transplantation in older adults. Journal of Geriatric Oncology, 14(8), 101623. -
Tolerability and Efficacy of the Anticluster of Differentiation 47 Antibody Magrolimab Combined With Azacitidine in Patients With Previously Untreated AML: Phase Ib Results.
Daver, N. G., Vyas, P., Kambhampati, S., Al Malki, M. M., Larson, R. A., Asch, A. S., … Sallman, D. A. (2023). Tolerability and Efficacy of the Anticluster of Differentiation 47 Antibody Magrolimab Combined With Azacitidine in Patients With Previously Untreated AML: Phase Ib Results. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2202604. -
Measurable residual disease conversion rate with consolidation chemotherapy in acute myeloid leukemia.
Gaut, D., Oliai, C., Boiarsky, J., Zhang, S., Salhotra, A., Azenkot, T., … Schiller, G. (2023). Measurable residual disease conversion rate with consolidation chemotherapy in acute myeloid leukemia. Leukemia & Lymphoma, 1–9. -
Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemia: Topline Ef cacy and Safety Results from the Pivotal Augment-101 Phase 2 Study
Aldoss, I., Issa, G. C., Thirman, M., DiPersio, J., Arellano, M., Blachly, J. S., … Stein, E. M. (2023). Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemia: Topline Ef cacy and Safety Results from the Pivotal Augment-101 Phase 2 Study. BLOOD. AMER SOC HEMATOLOGY. -
Treatment of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN): focus on the use of tagraxofusp and clinical considerations.
Pemmaraju, N., Madanat, Y. F., Rizzieri, D., Fazal, S., Rampal, R., Mannis, G., … Lane, A. A. (2024). Treatment of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN): focus on the use of tagraxofusp and clinical considerations. Leukemia & Lymphoma, 1–12. -
Analysis of Treatment Patterns and Outcomes in Patients Ages 60-74 in the PostVenetoclax Era
St Martin, E. C., Schwede, M., Fakhri, B., Gotlib, J., Liedtke, M., Shomali, W., … Mannis, G. (2023). Analysis of Treatment Patterns and Outcomes in Patients Ages 60-74 in the PostVenetoclax Era. BLOOD. AMER SOC HEMATOLOGY. -
Harnessing Artificial Intelligence for Risk Stratification in Acute Myeloid Leukemia (AML): Evaluating the Utility of Longitudinal Electronic Health Record (EHR) Data Via Graph Neural Networks
Sinha, R., Schwede, M., Ben Viggiano, Kuo, D., Henry, S., Wood, D., … Zhang, T. Y. (2023). Harnessing Artificial Intelligence for Risk Stratification in Acute Myeloid Leukemia (AML): Evaluating the Utility of Longitudinal Electronic Health Record (EHR) Data Via Graph Neural Networks. BLOOD. AMER SOC HEMATOLOGY. -
The Shifting Prognosis of FLT3 Mutations in Acute Myeloid Leukemia in the Era of Targeted Therapy: A Real-World Study Using Large-Scale Electronic Health Record Data
Schwede, M., Rodriguez, G., Henry, S., Wood, D., Mannis, G., Majeti, R., … Zhang, T. Y. (2023). The Shifting Prognosis of FLT3 Mutations in Acute Myeloid Leukemia in the Era of Targeted Therapy: A Real-World Study Using Large-Scale Electronic Health Record Data. BLOOD. AMER SOC HEMATOLOGY. -
Phase 1b/2 Trial of Enasidenib in Lower-Risk MDS and Nonproliferative CMML without Isocitrate Dehydrogenase Type 2 Mutations
Kuo, E., Santiago, V., Tanaka, K., Puram, V., Zhou, C., Tai, J. W., … Zhang, T. Y. (2023). Phase 1b/2 Trial of Enasidenib in Lower-Risk MDS and Nonproliferative CMML without Isocitrate Dehydrogenase Type 2 Mutations. BLOOD. AMER SOC HEMATOLOGY. -
Immunosuppression in Isocitrate Dehydrogenase Mutated Acute Myeloid Leukemia
Tai, J. W., Li, G., Tanaka, K., Gopakumar, J., Zhou, C., Linde, M. H., … Zhang, T. Y. (2023). Immunosuppression in Isocitrate Dehydrogenase Mutated Acute Myeloid Leukemia. BLOOD. AMER SOC HEMATOLOGY. -
Cladribine and Low-Dose Cytarabine-Based Salvage Therapy for Relapsed/Refractory AML in a Predominantly Venetoclax-Exposed Cohort
Cheung, E., Schumann, C., Zhang, T. Y., Fakhri, B., Gotlib, J., Liedtke, M., … Mannis, G. (2023). Cladribine and Low-Dose Cytarabine-Based Salvage Therapy for Relapsed/Refractory AML in a Predominantly Venetoclax-Exposed Cohort. BLOOD. AMER SOC HEMATOLOGY. -
Development of Circulating Tumor DNA (ctDNA) for Molecular Measurable Residual Disease (MRD) in Acute Myeloid Leukemia (AML)
Gunaratne, R., Zhou, C., Tai, J. W., Schwede, M., Tanaka, K., Alkaitis, M., … Zhang, T. Y. (2023). Development of Circulating Tumor DNA (ctDNA) for Molecular Measurable Residual Disease (MRD) in Acute Myeloid Leukemia (AML). BLOOD. AMER SOC HEMATOLOGY. -
Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemias: Efficacy and Safety Results from the Augment-101 Phase 1/2 Study
Aldoss, I., Issa, G. C., Thirman, M. J., DiPersio, J., Arellano, M., Blachly, J. S., … Stein, E. M. (2023). Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemias: Efficacy and Safety Results from the Augment-101 Phase 1/2 Study. BLOOD. AMER SOC HEMATOLOGY. -
Acute Myeloid Leukemia with Inv(3) or t(3;3): A Clinical and Cytogenetic Characterization of 40 Patients
Moscvin, M., Schwede, M., Mannis, G., & Zhang, T. Y. (2023). Acute Myeloid Leukemia with Inv(3) or t(3;3): A Clinical and Cytogenetic Characterization of 40 Patients. BLOOD. AMER SOC HEMATOLOGY. -
A Phase 2 Study with Volasertib for Ven-HMA Relapsed/Refractory Acute Myeloid Leukemia Patients Guided By a Predictive Precision Medicine Platform
Wagner, J., Lacher, M. D., Gu, C. J., Leonardi, C., & Mannis, G. (2023). A Phase 2 Study with Volasertib for Ven-HMA Relapsed/Refractory Acute Myeloid Leukemia Patients Guided By a Predictive Precision Medicine Platform. BLOOD. AMER SOC HEMATOLOGY. -
CD38 and BCL2 expression guides treatment with daratumumab and venetoclax in tagraxofusp-refractory blastic plasmacytoid dendritic cell neoplasm (BPDCN) featuring dynamic loss of CD123.
Hu, X., Ediriwickrema, A., Saleem, A., Tan, B., Pemmaraju, N., & Mannis, G. N. (2024). CD38 and BCL2 expression guides treatment with daratumumab and venetoclax in tagraxofusp-refractory blastic plasmacytoid dendritic cell neoplasm (BPDCN) featuring dynamic loss of CD123. Leukemia Research, 139, 107479. -
p53 immunohistochemistry as an ancillary tool for rapid assessment of residual disease in TP53-mutated acute myeloid leukemia and myelodysplastic syndromes.
Brar, N., Lawrence, L., Fung, E., Zehnder, J. L., Greenberg, P. L., Mannis, G. N., … Fernandez-Pol, S. (2024). p53 immunohistochemistry as an ancillary tool for rapid assessment of residual disease in TP53-mutated acute myeloid leukemia and myelodysplastic syndromes. American Journal of Clinical Pathology. -
Menin Inhibition With Revumenib for KMT2A-Rearranged Relapsed or Refractory Acute Leukemia (AUGMENT-101).
Issa, G. C., Aldoss, I., Thirman, M. J., DiPersio, J., Arellano, M., Blachly, J. S., … Stein, E. M. (2024). Menin Inhibition With Revumenib for KMT2A-Rearranged Relapsed or Refractory Acute Leukemia (AUGMENT-101). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2400826.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
- A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
- Feasibility of Telehealth Palliative Care and Digital Symptom Monitoring for Patients With Acute Myeloid Leukemia
- Venetoclax + Azacitidine vs. Induction Chemotherapy in AML
- Magrolimab Monotherapy or Magrolimab in Combination With Azacitidine in Participants With Hematological Malignancies
- Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia
- A Phase 1b Master Trial to Investigate CPX-351 in Subjects With Previously Untreated Acute Myeloid Leukemia
- Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN
- Study of Magrolimab Combinations in Participants With Myeloid Malignancies
- Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)
- IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML
- A Study to Assess the Effect of CC-95251 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndromes
Practice Locations
Hematologic Cancer Program Palo Alto, CA
Palo Alto, CAHematologic Cancer Program
875 Blake Wilbur Drive
Palo Alto , CA 94304
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Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
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