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Mild cognitive impairment

  • About
  • About
Overview
Causes
Types
  • Alzheimer's disease
  • Huntington's disease
  • Vascular dementia
  • Dementia with Lewy bodies
  • Frontotemporal dementia
  • Normal pressure hydrocephalus
  • Creutzfeldt-Jakob disease (prion disease)
  • Corticobasal degeneration
  • Mild cognitive impairment
Diagnosis
  • Patient history
  • Physical examination
  • Neurological evaluations
  • Cognitive and neuropsychological tests
  • Brain scans
  • Laboratory tests
  • Psychiatric evaluation
  • Presymptomatic testing
Risk Factors
Treatments
Prevention
FAQs
Overview
Causes
Types
  • Alzheimer's disease
  • Huntington's disease
  • Vascular dementia
  • Dementia with Lewy bodies
  • Frontotemporal dementia
  • Normal pressure hydrocephalus
  • Creutzfeldt-Jakob disease (prion disease)
  • Corticobasal degeneration
  • Mild cognitive impairment
Diagnosis
  • Patient history
  • Physical examination
  • Neurological evaluations
  • Cognitive and neuropsychological tests
  • Brain scans
  • Laboratory tests
  • Psychiatric evaluation
  • Presymptomatic testing
Risk Factors
Treatments
Prevention
FAQs

Mild Cognitive Impairment

Mild cognitive impairment refers to cognitive symptoms that are worse than expected for age, but not severe enough to interfere with normal activities or relationships. Like dementia, mild cognitive impairment is a descriptive term and not a specific disease; it also shares with dementia a similar list of possible underlying causes.

It is important to note that neurodegenerative diseases do not start the day that a patient can no longer drive a car, balance a checkbook, or prepare a meal. Instead, the changes that occur in the brain in Alzheimer's disease and other such illnesses begin insidiously, without any outward symptoms at first; patients progress gradually through a stage of mild cognitive impairment and then to dementia, often over a period of years. Frequently, the pattern of early symptoms is evident only in retrospect.

On the other hand, not all patients with mild cognitive impairment ever go on to develop dementia. Much research, including at the Stanford Center for Memory Disorders, focuses on how to determine which patients with mild cognitive impairment will worsen over time, and who will not. Diagnostic tests like advanced neuroimaging and the determination of certain protein levels in the blood and cerebrospinal fluid may yield valuable predictive information.

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Dr. Longo on Dementia Play Video | 3:17
Your Health: Alzheimer's Disease & Dementia Watch Video

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Closed Trials
Raloxifene for Women With Alzheimer's Disease Alzheimer's Disease, Dementia
A Study of Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD) Alzheimer's Disease, Dementia
221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease Alzheimer's Disease, Dementia
The Effect of Memantine on Brain Structure and Chemistry in Alzheimer's Disease Patients Alzheimer's Disease, Dementia
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