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Myasthenia Gravis Treatment

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Overview
Symptoms
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Diagnosis
Treatment
Overview
Symptoms
Causes
Diagnosis
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Myasthenia Gravis Treatment at Stanford

There is no cure for myasthenia gravis, but today's treatments can effectively treat the disease to reduce symptoms. We tailor your treatment plan to address your unique health needs.

Non-surgical Treatments for Myasthenia Gravis

Most patients require ongoing medical treatments for myasthenia gravis, including:

  • Medications that control the immune system
  • Medications that improve the transmission between nerve and muscle at the neuromuscular junction
  • Plasmapheresis, a procedure that removes abnormal antibodies from the blood
  • Immunoglobulin, a blood product that reduces the immune system’s attack on the body's own tissues

Thymectomy and Myasthenia Gravis

For reasons that remain unclear, some individuals with myasthenia gravis also have an abnormal thymus gland. Here's an overview of what experts know about the connection:

  • The thymus gland lies near the heart, beneath the sternum (breastbone), and is important to the development of the immune system in infancy and childhood.
  • The thymus gland normally shrinks during adulthood.
  • In people with myasthenia gravis, the thymus gland sometimes becomes hyperactive.
  • Some people with myasthenia gravis may have a tumor of the thymus gland called thymoma.
  • Some individuals with myasthenia gravis may benefit from having the gland removed in a surgery called thymectomy.

Neurologists in the Stanford Neuromuscular Program works closely with the Stanford thoracic surgeons to provide optimal care of people who need thymectomy to control myasthenia gravis.

Before coming to Stanford, Chief of Thoracic Surgery Division, Dr. Joseph Shrager, published the world's largest series of extended transcervical thymectomy surgeries. This study demonstrated that the operation is very effective, with far fewer complications and faster recovery than thymectomy performed through a large chest incision. Patients return home the day of surgery or the following day, and they generally return to their usual activities within a week.

Learn more about receiving collaborative care for myasthenia gravis from the Stanford Neuromuscular Program and Thoracic Surgery Clinic.

Myasthenia Gravis Clinical Trials

Stanford investigators regularly participate in research studies to better understand diseases like myasthenia gravis and to investigate new treatment approaches.

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Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Open Trials Closed Trials
Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study) Myasthenia Gravis
A Phase III, Open-Label, Extension Trial of ECU-MG-301 to Evaluate the Safety and Efficacy of Eculizumab in Subjects with Refractory Generalized Myasthenia Gravis (gMG)/ Alexion ECU-MG-302 Myasthenia Gravis
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Eculizumab in Subjects with Refractory Generalized Myasthenia Gravis (gMG) Myasthenia Gravis
"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Narcolepsy" Myasthenia Gravis, Narcolepsy

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