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Genetic testing can be done on several genes that affect HIV and the course of the infection. For example, a genetic mutation causing a protein defect called CCR5 delta 32 has been shown to be resistant to the HIV virus. Mutations in the major histocompatibility complex, class I, B (HLA-B) gene is also linked to the HIV virus. There are several variations in HLA-B that can either slow the progression of HIV to AIDS or speed it up. Mutations in the killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1(KIR3DL1) gene and the chemokine (C-C motif) ligand 3-like 1 (CCL3L1) gene have also been associated with varying rates of AIDS progression.
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.