Mark Nicolls

Pulmonologist

Associate Professor of Medicine (Pulmonary and Critical Care)

Center for Advanced Lung Disease

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-3633
Learn More About the Clinic Getting Here Make An Appointment

Chest Clinic

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-725-7061
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Professional Education

Residency: Stanford University School of Medicine (1996) CA

Board Certification: Internal Medicine, American Board of Internal Medicine (1996)

Board Certification, ABIM, Critical Care Medicine (1999)

Board Certification: Pulmonary Disease, American Board of Internal Medicine (1998)

Fellowship: University of Colorado School of Medicine (1999) CO

BS, University of Portland, Biology (1987)

Medical Education: Stanford University School of Medicine (1993) CA

Honors & Awards

Elected Member, The American Society for Clinical Investigation (2014-)

Administrative Appointments

Chief, Pulmonary and Critical Care Medicine (2010 - Present)

Program Director, Pulmonary and Critical Care Fellowship (2009 - 2010)

Faculty, Vera Moulton Wall Center For Pulmonary Vascular Disease (2007 - Present)

Member, Stanford Cardiovascular Institute (2007 - Present)

Director, Lung Immunology (2007 - Present)

Joint Appointment, Immunology & Rheumatology (2007 - Present)

Member, Institute for Immunity, Transplantation and Infection (2007 - Present)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Nuclear Factor ?B Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats.
Farkas, D., Alhussaini, A. A., Kraskauskas, D., Kraskauskiene, V., Cool, C. D., & Farkas, L. (2014). Nuclear Factor ?B Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats. American journal of respiratory cell and molecular biology, 51(3), 413-425.

Graft microvascular disease in solid organ transplantation.
Jiang, X., Sung, Y. K., Tian, W., Qian, J., Semenza, G. L., & Nicolls, M. R. (2014). Graft microvascular disease in solid organ transplantation. Journal of molecular medicine (Berlin, Germany), 92(8), 797-810.

Leukotrienes in pulmonary arterial hypertension
Tian, W., Jiang, X., Sung, Y. K., Qian, J., Yuan, K., & Nicolls, M. R. (2014). Leukotrienes in pulmonary arterial hypertension. IMMUNOLOGIC RESEARCH, 58(2-3), 387-393.

Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock
Beraud, A.-S., Guillamet, C. V., Hammes, J. L., Meng, L., Nicolls, M. R., & Hsu, J. L. (2014). Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 347(4), 295-298.

Application of a non-amplification-based technology to detect invasive fungal pathogens
Hsu, J. L., Binkley, J., Clemons, K. V., Stevens, D. A., Nicolls, M. R., & Holodniy, M. (2014). Application of a non-amplification-based technology to detect invasive fungal pathogens. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 78(2), 137-140.

Working toward immune tolerance in lung transplantation.
Jiang, X., & Nicolls, M. R. (2014). Working toward immune tolerance in lung transplantation. The Journal of clinical investigation, 1-4.

Impact of the Lung Allocation Score on Survival Beyond 1 Year.
Maxwell, B. G., Levitt, J. E., Goldstein, B. A., Mooney, J. J., Nicolls, M. R., & Dhillon, G. S. (2014). Impact of the Lung Allocation Score on Survival Beyond 1 Year. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Unique Predictors of Mortality in Patients With Pulmonary Arterial Hypertension Associated With Systemic Sclerosis in the Reveal Registry.
Chung, L., Farber, H. W., Benza, R., Miller, D. P., Parsons, L., & Zamanian, R. T. (2014). Unique Predictors of Mortality in Patients With Pulmonary Arterial Hypertension Associated With Systemic Sclerosis in the Reveal Registry. Chest.

Traumatic Brain Injury: Lungs in a RAGE.
Nicolls, M. R., & Laubach, V. E. (2014). Traumatic Brain Injury: Lungs in a RAGE. Science translational medicine, 6(252), 252fs34.

Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension.
Rabinovitch, M., Guignabert, C., Humbert, M., & Nicolls, M. R. (2014). Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circulation research, 115(1), 165-75.

Macrophages in solid organ transplantation.
Jiang, X., Tian, W., Sung, Y. K., Qian, J., & Nicolls, M. R. (2014). Macrophages in solid organ transplantation. Vascular cell, 6(1), 5-?.

Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles
Jiang, X., Malkovskiy, A. V., Tian, W., Sung, Y. K., Sun, W., & Nicolls, M. R. (2014). Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles. BIOMATERIALS, 35(2), 803-813.

The critical role of mRNA destabilizing protein heterogeneous nuclear ribonucleoprotein d in 3' untranslated region-mediated decay of low-density lipoprotein receptor mRNA in liver tissue.
Singh, A. B., Li, H., Kan, C. F., Dong, B., Nicolls, M. R., & Liu, J. (2014). The critical role of mRNA destabilizing protein heterogeneous nuclear ribonucleoprotein d in 3' untranslated region-mediated decay of low-density lipoprotein receptor mRNA in liver tissue. Arteriosclerosis, thrombosis, and vascular biology, 34(1), 8-16.

Complement components as potential therapeutic targets for asthma treatment.
Khan, M. A., Nicolls, M. R., Surguladze, B., & Saadoun, I. (2014). Complement components as potential therapeutic targets for asthma treatment. Respiratory medicine.

Temporal Response of the Human Virome to Immunosuppression and Antiviral Therapy
De Vlaminck, I., Khush, K. K., Strehl, C., Kohli, B., Luikart, H., & Quake, S. R. (2013). Temporal Response of the Human Virome to Immunosuppression and Antiviral Therapy. CELL, 155(5), 1178-1187.

Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia
Hsu, J. L., Khan, M. A., Sobel, R. A., Jiang, X., Clemons, K. V., & Nicolls, M. R. (2013). Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia. PLOS ONE, 8(10).

Blocking Macrophage Leukotriene B-4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension
Tian, W., Jiang, X., Tamosiuniene, R., Sung, Y. K., Qian, J., & Nicolls, M. R. (2013). Blocking Macrophage Leukotriene B-4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension. SCIENCE TRANSLATIONAL MEDICINE, 5(200).

Epithelial to mesenchymal transition in murine tracheal allotransplantation: an immunohistochemical observation.
Konoeda, C., Koinuma, D., Morishita, Y., Sano, A., Nagayama, K., & Murakawa, T. (2013). Epithelial to mesenchymal transition in murine tracheal allotransplantation: an immunohistochemical observation. Transplantation proceedings, 45(5), 1797-1801.

Targeting complement component 5a promotes vascular integrity and limits airway remodeling
Khan, M. A., Maasch, C., Vater, A., Klussmann, S., Morser, J., & Nicolls, M. R. (2013). Targeting complement component 5a promotes vascular integrity and limits airway remodeling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(15), 6061-6066.

Editorial: Developing Better Biomarkers for Connective Tissue DiseaseAssociated Interstitial Lung Disease: Citrullinated Hsp90 Autoantibodies in Rheumatoid Arthritis
Deane, K. D., & Nicolls, M. R. (2013). Editorial: Developing Better Biomarkers for Connective Tissue DiseaseAssociated Interstitial Lung Disease: Citrullinated Hsp90 Autoantibodies in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65(4), 864-868.

Complement-mediated microvascular injury leads to chronic rejection.
Khan, M. A., & Nicolls, M. R. (2013). Complement-mediated microvascular injury leads to chronic rejection. Advances in experimental medicine and biology, 735, 233-246.

Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus.
Jiang, X., Hsu, J. L., Tian, W., Yuan, K., Olcholski, M., & Nicolls, M. R. (2013). Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. Journal of molecular medicine (Berlin, Germany).

Pathobiology of pulmonary arterial hypertension and right ventricular failure
Voelkel, N. F., Gomez-Arroyo, J., Abbate, A., Bogaard, H. J., & Nicolls, M. R. (2012). Pathobiology of pulmonary arterial hypertension and right ventricular failure. EUROPEAN RESPIRATORY JOURNAL, 40(6), 1555-1565.

Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization
Mizuno, S., Farkas, L., Al Husseini, A., Farkas, D., Gomez-Arroyo, J., & Voelkel, N. F. (2012). Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 47(5), 679-687.

New methods for monitoring dynamic airway tissue oxygenation and perfusion in experimental and clinical transplantation
Khan, M. A., Dhillon, G., Jiang, X., Lin, Y.-C., & Nicolls, M. R. (2012). New methods for monitoring dynamic airway tissue oxygenation and perfusion in experimental and clinical transplantation. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 303(10), L861-L869.

New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis.
Nicolls, M. R., Mizuno, S., Taraseviciene-Stewart, L., Farkas, L., Drake, J. I., & Bogaard, H. J. (2012). New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary circulation, 2(4), 434-442.

Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth.
Hilgendorff, A., Parai, K., Ertsey, R., Juliana Rey-Parra, G., Thébaud, B., & Bland, R. D. (2012). Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. American journal of physiology. Lung cellular and molecular physiology, 303(3), L215-27.

Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth
Hilgendorff, A., Parai, K., Ertsey, R., Rey-Parra, G. J., Thebaud, B., & Bland, R. D. (2012). Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 303(3), L215-L227.

A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects
Gomez-Arroyo, J., Saleem, S. J., Mizuno, S., Syed, A. A., Bogaard, H. J., & Voelkel, N. F. (2012). A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 302(10), L977-L991.

Potential for overuse of corticosteroids and vasopressin in septic shock.
Hsu, J. L., Liu, V., Patterson, A. J., Martin, G. S., Nicolls, M. R., & Russell, J. A. (2012). Potential for overuse of corticosteroids and vasopressin in septic shock. Critical care (London, England), 16(5), 447.

CD4(+) T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants
Khan, M. A., Jiang, X., Dhillon, G., Beilke, J., Holers, V. M., & Nicolls, M. R. (2011). CD4(+) T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants. CIRCULATION RESEARCH, 109(11), 1290-U256.

Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension
Tamosiuniene, R., Tian, W., Dhillon, G., Wang, L., Sung, Y. K., & Nicolls, M. R. (2011). Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension. CIRCULATION RESEARCH, 109(8), 867-U120.

Inhibiting Lung Elastase Activity Enables Lung Growth in Mechanically Ventilated Newborn Mice
Hilgendorff, A., Parai, K., Ertsey, R., Jain, N., Navarro, E. F., & Bland, R. D. (2011). Inhibiting Lung Elastase Activity Enables Lung Growth in Mechanically Ventilated Newborn Mice. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 184(5), 537-546.

Regulatory T Cells and Pulmonary Hypertension
Tamosiuniene, R., & Nicolls, M. R. (2011). Regulatory T Cells and Pulmonary Hypertension. TRENDS IN CARDIOVASCULAR MEDICINE, 21(6), 166-171.

Adenovirus-mediated HIF-1 alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
Jiang, X., Khan, M. A., Tian, W., Beilke, J., Natarajan, R., & Nicolls, M. R. (2011). Adenovirus-mediated HIF-1 alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection. JOURNAL OF CLINICAL INVESTIGATION, 121(6), 2336-2349.

Survival in Pulmonary Hypertension Registries The Importance of Incident Cases Response
Chung, L., Liu, J., Parsons, L. S., Hassoun, P. M., McGoon, M. D., & Zamanian, R. T. (2011). Survival in Pulmonary Hypertension Registries The Importance of Incident Cases Response. CHEST, 139(6), 1548-1549.

Immunomodulatory strategies prevent the development of autoimmune emphysema
Hanaoka, M., Nicolls, M. R., Fontenot, A. P., Kraskauskas, D., Mack, D. G., & Taraseviciene-Stewart, L. (2010). Immunomodulatory strategies prevent the development of autoimmune emphysema. RESPIRATORY RESEARCH, 11.

Strategic Plan for Lung Vascular Research An NHLBI-ORDR Workshop Report
Erzurum, S., Rounds, S. I., Stevens, T., Aldred, M., Aliotta, J., & Moore, T. M. (2010). Strategic Plan for Lung Vascular Research An NHLBI-ORDR Workshop Report. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(12), 1554-1562.

Characterization of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension From REVEAL Identifying Systemic Sclerosis as a Unique Phenotype
Chung, L., Liu, J., Parsons, L., Hassoun, P. M., McGoon, M., & Zamanian, R. T. (2010). Characterization of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension From REVEAL Identifying Systemic Sclerosis as a Unique Phenotype. CHEST, 138(6), 1383-1394.

Bronchial blood supply after lung transplantation without bronchial artery revascularization
Nicolls, M. R., & Zamora, M. R. (2010). Bronchial blood supply after lung transplantation without bronchial artery revascularization. CURRENT OPINION IN ORGAN TRANSPLANTATION, 15(5), 563-567.

Lung Transplant Airway Hypoxia A Diathesis to Fibrosis?
Dhillon, G. S., Zamora, M. R., Roos, J. E., Sheahan, D., Sista, R. R., & Nicolls, M. R. (2010). Lung Transplant Airway Hypoxia A Diathesis to Fibrosis?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(2), 230-236.

Immune Reconstitution Prevents Autoimmune Inflammation and Right Ventricular Remodeling in Immunodeficiency-Associated Pulmonary Hypertension
Tamosiuniene, R., Long, C., Ambler, K., Sung, Y., Gera, L., & Nicolls, M. (2009). Immune Reconstitution Prevents Autoimmune Inflammation and Right Ventricular Remodeling in Immunodeficiency-Associated Pulmonary Hypertension. CIRCULATION, 120(18), S1135-S1135.

Prevention of Adverse Right Ventricular Remodeling and Autoimmune Inflammation after Splenocyte Therapy in Pulmonary Hypertension: Contribution of HOX11+, C-kit+, FOXP3+Cells
Tamosiuniene, R., Long, C., Ambler, K., Wang, L., Gera, L., & Nicolls, M. (2009). Prevention of Adverse Right Ventricular Remodeling and Autoimmune Inflammation after Splenocyte Therapy in Pulmonary Hypertension: Contribution of HOX11+, C-kit+, FOXP3+Cells. CLINICAL IMMUNOLOGY, 131, S69-S70.

Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension
Ulrich, S., Nicolls, M. R., Taraseviciene, L., Speich, R., & Voelkel, N. (2008). Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension. RESPIRATION, 75(3), 272-280.

Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis
Babu, A. N., Murakawa, T., Thurman, J. M., Miller, E. J., Henson, P. M., & Nicolls, M. R. (2007). Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. JOURNAL OF CLINICAL INVESTIGATION, 117(12), 3774-3785.

Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin
El Mezayen, R., El Gazzar, M., Seeds, M. C., McCall, C. E., Dreskin, S. C., & Nicolls, M. R. (2007). Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. IMMUNOLOGY LETTERS, 111(1), 36-44.

Oxidant stress, immune dysregulation, and vascular function in type I diabetes
Nicolls, M. R., Haskins, K., & Flores, S. C. (2007). Oxidant stress, immune dysregulation, and vascular function in type I diabetes. ANTIOXIDANTS & REDOX SIGNALING, 9(7), 879-889.

Hypoxia and the lung: Beyond hypoxic vasoconstriction
Nicolls, M. R., & Voelkel, N. F. (2007). Hypoxia and the lung: Beyond hypoxic vasoconstriction. ANTIOXIDANTS & REDOX SIGNALING, 9(6), 741-743.

Transfer of allograft specific tolerance requires CD4(+)CD25(+)T cells but not interleukin-4 or transforming growth factor-beta and cannot induce tolerance to linked antigens
Hall, B. M., Plain, K. M., Verma, N. D., Tran, G. T., Boyd, R., & Hodgkinson, S. J. (2007). Transfer of allograft specific tolerance requires CD4(+)CD25(+)T cells but not interleukin-4 or transforming growth factor-beta and cannot induce tolerance to linked antigens. TRANSPLANTATION, 83(8), 1075-1084.

Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation
El Gazzar, M. A., El Mezayen, R., Nicolls, M. R., & Dreskin, S. C. (2007). Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(4), 556-564.

The matrix comes to lung transplantation
Babu, A. N., & Nicolls, M. R. (2007). The matrix comes to lung transplantation. TRANSPLANTATION, 83(6), 683-684.

Angiogenesis in chronic lung disease
Voelkel, N. F., Douglas, I. S., & Nicolls, M. (2007). Angiogenesis in chronic lung disease. CHEST, 131(3), 874-879.

Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling.
Nicolls MR*, Taraseviciene-Stewart L, Kraskauskas D, Scerbavicius R, Burns N, & Voelkel NF (*co-1st author). (2007). Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling. Am J Respir Crit Care Med, 175(12).

Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?
Taraseviciene-Stewart, L., Douglas, I. S., Nana-Sinkam, P. S., Lee, J. D., Tuder, R. M., & Voelkel, N. F. (2006). Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?. Proceedings of the American Thoracic Society, 3(8), 687-690.

Mechanisms of autoimmune emphysema.
Taraseviciene-Stewart, L., Burns, N., Kraskauskas, D., Nicolls, M. R., Tuder, R. M., & Voelkel, N. F. (2006). Mechanisms of autoimmune emphysema. Proceedings of the American Thoracic Society, 3(6), 486-487.

Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation
El Mezayen, R., El Gazzar, M., Nicolls, M. R., Marecki, J. C., Dreskin, S. C., & Nomiyama, H. (2006). Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. IMMUNOLOGY LETTERS, 106(1), 72-81.

Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma
El Gazzar, M., El Mezayen, R., Nicolls, M. R., Marecki, J. C., & Dreskin, S. C. (2006). Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1760(7), 1088-1095.

Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation
El Gazzar, M., El Mezayen, R., Marecki, J. C., Nicolls, M. R., Canastar, A., & Dreskin, S. C. (2006). Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation. INTERNATIONAL IMMUNOPHARMACOLOGY, 6(7), 1135-1142.

LFA-1 (CD11a) as a therapeutic target
Nicolls, M. R., & Gill, R. G. (2006). LFA-1 (CD11a) as a therapeutic target. AMERICAN JOURNAL OF TRANSPLANTATION, 6(1), 27-36.

Autoimmunity and pulmonary hypertension: a perspective
Nicolls, M. R., Taraseviciene-Stewart, L., Rai, P. R., Badesch, D. B., & Voelkel, N. F. (2005). Autoimmunity and pulmonary hypertension: a perspective. EUROPEAN RESPIRATORY JOURNAL, 26(6), 1110-1118.

The protective role of T-lymphocytes in pulmonary vascular remodeling
Taraseviciene-Stewart, L., Kraskauskas, D., Scerbavicins, R., Burns, N., Cool, C. D., & Voelkel, N. F. (2005). The protective role of T-lymphocytes in pulmonary vascular remodeling. CHEST, 128(6), 571S-572S.

Type 2 diabetes mellitus as a conformational disease.
Hayden, M. R., Tyagi, S. C., Kerklo, M. M., & Nicolls, M. R. (2005). Type 2 diabetes mellitus as a conformational disease. JOP : Journal of the pancreas, 6(4), 287-302.

Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibroses?
Douglas, I. S., & Nicolls, T. R. (2005). Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibroses?. JOURNAL OF CLINICAL INVESTIGATION, 115(5), 1133-1136.

Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: Implications for the role of respiratory epithelium as a modulator of fibrosis
Murakawa, T., Kerklo, M. M., Zamora, M. R., Wei, Y., Gill, R. G., & Nicolls, M. R. (2005). Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: Implications for the role of respiratory epithelium as a modulator of fibrosis. JOURNAL OF IMMUNOLOGY, 174(7), 3869-3879.

An animal model of autoimmune emphysema
Taraseviciene-Stewart, L., Scerbavicius, R., Chloe, K. H., Moore, M., Sullivan, A., & Voelkel, N. F. (2005). An animal model of autoimmune emphysema. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 171(7), 734-742.

Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation
Zamora, M. R., Nicolls, M. R., Hodges, T. N., Marquesen, J., Astor, T., & Weill, D. (2004). Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation. AMERICAN JOURNAL OF TRANSPLANTATION, 4(10), 1635-1642.

The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimer's Disease
Nicolls, M. R. (2004). The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimer's Disease. CURRENT ALZHEIMER RESEARCH, 1(1), 47-54.

Gene microarray study corroborates proteomic findings in rodent islet cells
Cardozo, A. K., Berthou, L., Kruhoffer, M., Orntoft, T., Nicolls, M. R., & Eizirik, D. L. (2003). Gene microarray study corroborates proteomic findings in rodent islet cells. JOURNAL OF PROTEOME RESEARCH, 2(5), 553-555.

Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets
Nicolls, M. R., D'Antonio, J. M., Hutton, J. C., Gill, R. G., Czwornog, J. L., & Duncan, M. W. (2003). Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets. JOURNAL OF PROTEOME RESEARCH, 2(2), 199-205.

CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways
Nicolls, M. R., Coulombe, M., Beilke, J., Gelhuas, H. C., & Gill, R. G. (2002). CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways. JOURNAL OF IMMUNOLOGY, 169(9), 4831-4839.

Interferon-gamma is not a universal requirement for islet allograft survival
Nicolls, M. R., Coulombe, M., Diamond, A. S., Beilke, J., & Gill, R. G. (2002). Interferon-gamma is not a universal requirement for islet allograft survival. TRANSPLANTATION, 74(4), 472-477.

Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4
Tran, G. T., CARTER, N., He, X. Y., Spicer, T. S., Plain, K. M., & Hodgkinson, S. J. (2001). Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4. INTERNATIONAL IMMUNOLOGY, 13(9), 1109-1120.

The basis of immunogenicity of endocrine allografts
Nicolls, M. R., Coulombe, M., & Gill, R. G. (2001). The basis of immunogenicity of endocrine allografts. CRITICAL REVIEWS IN IMMUNOLOGY, 21(1-3), 87-101.

Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4
Nicolls, M. R., Coulombe, M., Yang, H., Bolwerk, A., & Gill, R. G. (2000). Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4. JOURNAL OF IMMUNOLOGY, 164(7), 3627-3634.

Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome
Nicolls, M. R., Terada, L. S., Tuder, R. M., Prindiville, S. A., & Schwarz, M. I. (1998). Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 158(4), 1302-1305.

INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES
WOODLEY, S. L., Gurley, K. E., HOFFMANN, S. L., Nicolls, M. R., Hagberg, R., & Strober, S. (1993). INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES. TRANSPLANTATION, 56(6), 1443-1447.

INDUCTION OF LONG-TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI-CD3-LIKE MONOCLONAL-ANTIBODY
Nicolls, M. R., AVERSA, G. G., Pearce, N. W., Spinelli, A., Berger, M. F., & Hall, B. M. (1993). INDUCTION OF LONG-TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI-CD3-LIKE MONOCLONAL-ANTIBODY. TRANSPLANTATION, 55(3), 459-468.