Biography
Dr. Gubatan is a physician scientist, board-certified gastroenterologist, and instructor of medicine at Stanford University School of Medicine. He earned his medical degree from Harvard Medical School and completed his internship and residency in internal medicine at Harvard's Beth Israel Deaconess Medical Center. He completed his gastroenterology fellowship at Stanford where he served as chief fellow and was an American Gastroenterological Association (AGA) editorial fellow for Gastroenterology. Dr. Gubatan’s research is focused on translational studies using single-cell multi-omics to understand mechanisms of therapy failure, elucidate the role of host immune and gut microbiome interactions in the pathogenesis of inflammatory bowel disease (IBD), and develop precision medicine strategies to improve outcomes in patients with IBD. Dr. Gubatan’s work has been featured in Gastroenterology, Gut, American Journal of Gastroenterology, Clinical Gastroenterology and Hepatology, Alimentary Pharmacology and Therapeutics, Journal of Crohns & Colitis, and Inflammatory Bowel Diseases. Dr. Gubatan's research and career development has been supported by a Chan Zuckerberg Biohub Physician Scientist Scholar Award, a Stanford Translational Research and Applied Medicine (TRAM) Scholar Award, an NIH NIDDK LRP Award, and a Doris Duke Charitable Foundation Physician Scientist Fellowship Award.
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Professional Summary
Education & Certifications
- Fellowship: Stanford University Division of Gastroenterology and Hepatology (2021) CA
- Board Certification: American Board of Internal Medicine, Gastroenterology (2021)
- Board Certification: American Board of Internal Medicine, Internal Medicine (2017)
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- Residency: Beth Israel Deaconess Medical Center Internal Medicine Residency (2017) MA
- Medical Education: Harvard Medical School (2014) MA
- Fellowship, Stanford University School of Medicine, Gastroenterology (2021)
- Residency, Beth Israel Deaconess Medical Center, Harvard Medical School, Internal Medicine (2017)
- M.D., Harvard Medical School, Medicine (2014)
- B.S., Michigan Tech University, Biochemistry and Molecular Biology (2010)
Honors & Awards
- ACG Outstanding Poster Presenter Award, American College of Gastroenterology (ACG) (2021)
- AGA FORWARD Scholar, American Gastroenterological Association (2023-2025)
- AGA Gastroenterology Editorial Fellow, American Gastroenterological Association (AGA) (2020-2021)
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- Ambassador Award, Department of Chemistry, Michigan Tech University (2010)
- Amgen Scholarship, Stanford University School of Medicine (2009)
- Barry M. Goldwater Scholarship, The Barry Goldwater Scholarship and Excellence in Education Foundation (2009)
- Best Original Basic Science Article of 2020 Finalist, Inflammatory Bowel Diseases Journal (2020)
- Chan Zuckerberg Biohub Physician Scientist Scholar Award, Chan Zuckerberg Biohub (2020-2023)
- Chief Fellow, Division of Gastroenterology and Hepatology, Stanford University (2020-2021)
- Clinical Research Loan Repayment Program (LRP) Award, National Institutes of Health (NIH)/NIDDK (2020-2024)
- Digestive Disease Week 2024 Poster of Distinction Award, American Gastroenterological Association (2024)
- Doris Duke Physician Scientist Fellowship Award, Doris Duke Charitable Foundation (DDCF) (2021-2023)
- Early Career Investigator Recognition at Digestive Disease Week, American Gastroenterological Association (AGA) (2022)
- Gut Microbiota for Health (GMFH) World Summit Top Abstract Award, Gut Microbiota for Health (2024)
- Harvard Dean Advisory Council Meeting Immunology Research Award, Harvard University (2011)
- Harvard Medical School Class of 1951 Endowed Scholarship, Harvard Medical School (2013)
- Harvard Medical School Research Fellowship, Harvard Medical School (2011)
- Harvard Open Access Publishing Equity (HOPE) Award, Harvard University (2016)
- NCSCG Symposium 1st Place Abstract Award, Northern California Society for Clinical Gastroenterology (2021)
- Outstanding Abstract Award, Resident & Fellow Poster Competition, Beth Israel Deaconess Medical Center, Harvard (2016)
- Outstanding Reviewer Award, Experimental Biology and Medicine (2019)
- Outstanding Senior Award, Department of Chemistry, Michigan Tech University (2010)
- Robert W. Summers Grant Award, American Society for Gastrointestinal Endoscopy (ASGE) (2019)
- Senior Resident Medicine Grand Rounds Research Award, Beth Israel Deaconess Medical Center, Harvard University (2017)
- Stanford Pediatric IBD and Celiac Disease Research Award, Maternal & Child Health Research Institute (MCHRI) (2022-2024)
- Stanford Translational Research and Applied Medicine (TRAM) Scholar Award, Stanford University (2020-2022)
- Summa Cum Laude, Michigan Tech University (2010)
- Third Annual Inflammatory Bowel Disease (IBD) Summit for Fellows Travel Award, Vindico Medical Education (2019)
- Top Downloaded Paper Award in Alimentary Pharmacology & Therapeutics, Wiley Publishing (2020)
Memberships
- Member, American Gastroenterological Association (AGA) (2016 - Present)
- Member, American College of Gastroenterology (ACG) (2016 - Present)
- Member, Crohn’s & Colitis Foundation (CCF) (2019 - Present)
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- Member, European Crohn’s and Colitis Organisation (ECCO) (2016 - Present)
- Member, Cochrane Collaboration (2020 - Present)
- Member, American Society of Gastrointestinal Endoscopy (ASGE) (2018 - Present)
Publications
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Multistrain influenza protection induced by a nanoparticulate mucosal immunotherapeutic
Tai, W., Roberts, L., Seryshev, A., Gubatan, J. M., Bland, C. S., Zabriskie, R., … Corry, D. B. (2011). Multistrain influenza protection induced by a nanoparticulate mucosal immunotherapeutic. MUCOSAL IMMUNOLOGY, 4(2), 197–207. -
Cannabis Abuse Is Increasing and Associated with Increased Emergency Department Utilization in Gastroenterology Patients
Gubatan, J., Staller, K., Barshop, K., & Kuo, B. (2016). Cannabis Abuse Is Increasing and Associated with Increased Emergency Department Utilization in Gastroenterology Patients. DIGESTIVE DISEASES AND SCIENCES, 61(7), 1844–52. -
Hypercalcemia associated with isolated bone marrow sarcoidosis in a patient with underlying monoclonal gammopathy of undetermined significance: case report and review of literature.
Gubatan, J., Wang, X., Louissaint, A., Mahindra, A., & Vanderpool, J. (2016). Hypercalcemia associated with isolated bone marrow sarcoidosis in a patient with underlying monoclonal gammopathy of undetermined significance: case report and review of literature. Biomarker Research, 4, 18-? -
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Hemorrhage from Extra-Antral Gastric Antral Vascular Ectasia in a Patient with Duodenal Heterotopic Gastric Mucosa.
Gubatan, J., Raines, N., Khosravi, H., Challies, T. L., & Berzin, T. M. (2016). Hemorrhage from Extra-Antral Gastric Antral Vascular Ectasia in a Patient with Duodenal Heterotopic Gastric Mucosa. Case Reports in Gastrointestinal Medicine, 2016, 4325302-? -
Low Serum Vitamin D During Remission Increases Risk of Clinical Relapse in Patients With Ulcerative Colitis.
Gubatan, J., Mitsuhashi, S., Zenlea, T., Rosenberg, L., Robson, S., & Moss, A. C. (2017). Low Serum Vitamin D During Remission Increases Risk of Clinical Relapse in Patients With Ulcerative Colitis. Clinical Gastroenterology and Hepatology , 15(2), 240–46 e1. -
Reply.
Gubatan, J. M. B., & Moss, A. C. (2017). Reply. Clinical Gastroenterology and Hepatology . -
Higher serum vitamin D levels are associated with protective serum cytokine profiles in patients with ulcerative colitis.
Gubatan, J., Mitsuhashi, S., Longhi, M. S., Zenlea, T., Rosenberg, L., Robson, S., & Moss, A. C. (2018). Higher serum vitamin D levels are associated with protective serum cytokine profiles in patients with ulcerative colitis. Cytokine, 103, 38–45. -
Vitamin D in inflammatory bowel disease: more than just a supplement.
Gubatan, J., & Moss, A. C. (2018). Vitamin D in inflammatory bowel disease: more than just a supplement. Current Opinion in Gastroenterology, 34(4), 217–25. -
Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease.
Gubatan, J., Chou, N. D., Nielsen, O. H., & Moss, A. C. (2019). Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease. Alimentary Pharmacology & Therapeutics. -
Managing vitamin D deficiency in inflammatory bowel disease.
Nielsen, O. H., Hansen, T. I., Gubatan, J. M., Jensen, K. B., & Rejnmark, L. (2019). Managing vitamin D deficiency in inflammatory bowel disease. Frontline Gastroenterology, 10(4), 394–400. -
Double Threat: Interplay of Celiac Disease with Inflammatory Bowel Disease.
Gubatan, J., Triadafilopoulos, G., & Fernandez-Becker, N. Q. (2019). Double Threat: Interplay of Celiac Disease with Inflammatory Bowel Disease. Digestive Diseases and Sciences. -
Cathelicidin Mediates a Protective Role of Vitamin D in Ulcerative Colitis and Human Colonic Epithelial Cells.
Gubatan, J., Mehigan, G. A., Villegas, F., Mitsuhashi, S., Longhi, M. S., Malvar, G., … Moss, A. C. (2020). Cathelicidin Mediates a Protective Role of Vitamin D in Ulcerative Colitis and Human Colonic Epithelial Cells. Inflammatory Bowel Diseases. -
Novel use of endoscopic morcellator to clear large obscuring clot in patient with upper-GI bleed.
Gubatan, J., Kwo, P., & Hwang, J. H. (2020). Novel use of endoscopic morcellator to clear large obscuring clot in patient with upper-GI bleed. VideoGIE : an Official Video Journal of the American Society for Gastrointestinal Endoscopy, 5(2), 58–60. -
Gastric Leiomyosarcoma Unmasked by Bleeding From a Percutaneous Endoscopic Gastrostomy Tube.
Gubatan, J., & Shah, N. (2020). Gastric Leiomyosarcoma Unmasked by Bleeding From a Percutaneous Endoscopic Gastrostomy Tube. ACG Case Reports Journal, 7(1), e00301. -
SARS-CoV-2 Testing, Prevalence, and Predictors of COVID-19 in Patients with Inflammatory Bowel Disease in Northern California.
Gubatan, J., Levitte, S., Balabanis, T., Patel, A., Sharma, A., & Habtezion, A. (2020). SARS-CoV-2 Testing, Prevalence, and Predictors of COVID-19 in Patients with Inflammatory Bowel Disease in Northern California. Gastroenterology. -
Prevalence, risk factors and clinical outcomes of COVID-19 in patients with a history of pancreatitis in Northern California.
Gubatan, J., Levitte, S., Patel, A., Balabanis, T., Sharma, A., Jones, E., … Habtezion, A. (2020). Prevalence, risk factors and clinical outcomes of COVID-19 in patients with a history of pancreatitis in Northern California. Gut. -
Biologics for Inflammatory Bowel Disease and their Safety in Pregnancy: A Systematic Review and Meta-analysis.
Nielsen, O. H., Gubatan, J. M., Juhl, C. B., Streett, S. E., & Maxwell, C. (2020). Biologics for Inflammatory Bowel Disease and their Safety in Pregnancy: A Systematic Review and Meta-analysis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. -
Are Proton Pump Inhibitors Contributing to SARS-COV-2 Infection?
Tarlow, B., Gubatan, J., Khan, M. A., & Cholankeril, G. (2020). Are Proton Pump Inhibitors Contributing to SARS-COV-2 Infection? The American Journal of Gastroenterology. -
Mucosal vitamin D signaling in inflammatory bowel disease.
Kellermann, L., Jensen, K. B., Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A., & Nielsen, O. H. (2020). Mucosal vitamin D signaling in inflammatory bowel disease. Autoimmunity Reviews, 102672. -
Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis.
Gubatan, J., Nielsen, O. H., Levitte, S., Juhl, C. B., Maxwell, C., Streett, S. E., & Habtezion, A. (2020). Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis. The American Journal of Gastroenterology. -
Reply to Letter to the Editor: What is the incidence of COVID-19 in patients with IBD in western countries?
Gubatan, J., Sinha, S. R., & Habtezion, A. (2021). Reply to Letter to the Editor: What is the incidence of COVID-19 in patients with IBD in western countries? Gastroenterology. -
Gastric Mucosal Immune Profiling and Dysregulation in Idiopathic Gastroparesis.
Gottfried-Blackmore, A., Namkoong, H., Adler, E., Martin, B., Gubatan, J., Fernandez-Becker, N., … Habtezion, A. (2021). Gastric Mucosal Immune Profiling and Dysregulation in Idiopathic Gastroparesis. Clinical and Translational Gastroenterology, 12(5), e00349. -
Artificial intelligence applications in inflammatory bowel disease: Emerging technologies and future directions.
Gubatan, J., Levitte, S., Patel, A., Balabanis, T., Wei, M. T., & Sinha, S. R. (2021). Artificial intelligence applications in inflammatory bowel disease: Emerging technologies and future directions. World Journal of Gastroenterology, 27(17), 1920–1935. -
Vitamin D is Associated with a4ß7+ Immunophenotypes and Predicts Vedolizumab Therapy Failure in Patients with Inflammatory Bowel Disease.
Gubatan, J., Rubin, S. J., Bai, L., Haileselassie, Y., Levitte, S., Balabanis, T., … Habtezion, A. (2021). Vitamin D is Associated with a4ß7+ Immunophenotypes and Predicts Vedolizumab Therapy Failure in Patients with Inflammatory Bowel Disease. Journal of Crohn's & Colitis. -
Gastrointestinal symptoms and healthcare utilization have increased among patients with functional gastrointestinal and motility disorders during the COVID-19 pandemic.
Gubatan, J., Zikos, T., Spear Bishop, E., Wu, J., Gottfried, A., Becker, L., … Neshatian, L. (2021). Gastrointestinal symptoms and healthcare utilization have increased among patients with functional gastrointestinal and motility disorders during the COVID-19 pandemic. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society, e14243. -
Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease.
Weingarden, A. R., Rubin, S. J., & Gubatan, J. (2021). Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease. World Journal of Gastrointestinal Oncology, 13(8), 772–798. -
Anti-Integrins for the Treatment of Inflammatory Bowel Disease: Current Evidence and Perspectives.
Gubatan, J., Keyashian, K., Rubin, S. J., Wang, J., Buckman, C. A., & Sinha, S. (2021). Anti-Integrins for the Treatment of Inflammatory Bowel Disease: Current Evidence and Perspectives. Clinical and Experimental Gastroenterology, 14, 333–342. -
Dual targeting of lymphocyte homing and retention through a4ß7 and aEß7 inhibition in inflammatory bowel disease.
Dai, B., Hackney, J. A., Ichikawa, R., Nguyen, A., Elstrott, J., Orozco, L. D., … Yi, T. (2021). Dual targeting of lymphocyte homing and retention through a4ß7 and aEß7 inhibition in inflammatory bowel disease. Cell Reports. Medicine, 2(8), 100381. -
COVID-19 PANDEMIC INCREASED HEALTHCARE UTILIZATION AMONG PATIENTS WITH FUNCTIONAL GASTROINTESTINAL DISORDERS
Gubatan, J. M., Zikos, T., Wu, J., Spear, E., Gottfried, A. C., Becker, L. S., … Nashatian, L. (2021). COVID-19 PANDEMIC INCREASED HEALTHCARE UTILIZATION AMONG PATIENTS WITH FUNCTIONAL GASTROINTESTINAL DISORDERS. GASTROENTEROLOGY. W B SAUNDERS CO-ELSEVIER INC. -
Antimicrobial peptides and the gut microbiome in inflammatory bowel disease.
Gubatan, J., Holman, D. R., Puntasecca, C. J., Polevoi, D., Rubin, S. J., & Rogalla, S. (2021). Antimicrobial peptides and the gut microbiome in inflammatory bowel disease. World Journal of Gastroenterology, 27(43), 7402–7422. -
Immune Checkpoint Inhibitor-Mediated Colitis Is Associated With Improved Cancer Overall Survival
Weingarden, A. R., Gubatan, J., Balabanis, T., Patel, A., Singh, S., & Habtezion, A. (2021). Immune Checkpoint Inhibitor-Mediated Colitis Is Associated With Improved Cancer Overall Survival. AMERICAN JOURNAL OF GASTROENTEROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Paternal Biologic and Thiopurine Exposure in Inflammatory Bowel Disease and Association With Adverse Pregnancy Outcomes and Semen Parameters: A Systematic Review and Meta-Analysis
Gubatan, J., Barber, G., Nielsen, O. H., Juhl, C., Maxwell, C., Eisenberg, M., & Streett, S. (2021). Paternal Biologic and Thiopurine Exposure in Inflammatory Bowel Disease and Association With Adverse Pregnancy Outcomes and Semen Parameters: A Systematic Review and Meta-Analysis. AMERICAN JOURNAL OF GASTROENTEROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Biologic Therapy in Patients With Perianal Crohn's Disease and Association With Long-Term Rates of Surgical and Clinical Outcomes
Gubatan, J., Frost, S., Levitte, S., & Keyashian, K. (2021). Biologic Therapy in Patients With Perianal Crohn's Disease and Association With Long-Term Rates of Surgical and Clinical Outcomes. AMERICAN JOURNAL OF GASTROENTEROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Selective tyrosine kinase 2 inhibitors in inflammatory bowel disease.
Nielsen, O. H., Boye, T. L., Chakravarti, D., & Gubatan, J. (2022). Selective tyrosine kinase 2 inhibitors in inflammatory bowel disease. Trends in Pharmacological Sciences. -
Disease exacerbation is common in inflammatory bowel disease patients treated with immune checkpoint inhibitors for malignancy.
Rubin, S. J., Balabanis, T., Gubatan, J., & Habtezion, A. (2022). Disease exacerbation is common in inflammatory bowel disease patients treated with immune checkpoint inhibitors for malignancy. World Journal of Clinical Cases, 10(6), 1787–1794. -
IMMUNOMODULATORY EFFECTS OF NON-INVASIVE VAGAL NERVE STIMULATION THERAPY IN IDIOPATHIC GASTROPARESIS
Gottfried, A. C., Namkoong, H., Adler, E. P., Gubatan, J. M., Lei, C., Fernandez-Becker, N., … Habtezion, A. (2021). IMMUNOMODULATORY EFFECTS OF NON-INVASIVE VAGAL NERVE STIMULATION THERAPY IN IDIOPATHIC GASTROPARESIS. GASTROENTEROLOGY. W B SAUNDERS CO-ELSEVIER INC. -
Rates and Predictors of Long-term Clinical Outcomes in Patients With Perianal Crohn's Disease on Biologic Therapy.
Gubatan, J., Frost, S., Levitte, S., & Keyashian, K. (2022). Rates and Predictors of Long-term Clinical Outcomes in Patients With Perianal Crohn's Disease on Biologic Therapy. Journal of Clinical Gastroenterology. -
p38? and p38d as biomarkers in the interplay of colon cancer and inflammatory bowel diseases.
Fajardo, P., Taskova, M., Martín-Serrano, M. A., Hansen, J., Slott, S., Jakobsen, A. K., … Cuenda, A. (2022). p38? and p38d as biomarkers in the interplay of colon cancer and inflammatory bowel diseases. Cancer Communications (London, England). -
Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-Analysis.
Gubatan, J., Barber, G. E., Nielsen, O. H., Juhl, C. B., Maxwell, C., Eisenberg, M. L., & Streett, S. E. (2022). Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-Analysis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. -
Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer.
Gubatan, J., Boye, T. L., Temby, M., Sojwal, R. S., Holman, D. R., Sinha, S. R., … Nielsen, O. H. (2022). Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer. Microorganisms, 10(7). -
The Tumor Immune Microenvironment in Pancreatic Ductal Adenocarcinoma: Neither Hot nor Cold.
Rubin, S. J., Sojwal, R. S., Gubatan, J., & Rogalla, S. (2022). The Tumor Immune Microenvironment in Pancreatic Ductal Adenocarcinoma: Neither Hot nor Cold. Cancers, 14(17). -
De Novo Diagnosis of Lymphocytic Colitis After SARS-CoV-2 Vaccination.
Lee, P., Wei, M. T., Gubatan, J., Forgó, E., Berry, G. J., Verma, R., & Friedland, S. (2022). De Novo Diagnosis of Lymphocytic Colitis After SARS-CoV-2 Vaccination. ACG Case Reports Journal, 9(9), e00849. -
Immune checkpoint inhibitor-mediated colitis is associated with cancer overall survival.
Weingarden, A. R., Gubatan, J., Singh, S., Balabanis, T. C., Patel, A., Sharma, A., & Habtezion, A. (2022). Immune checkpoint inhibitor-mediated colitis is associated with cancer overall survival. World Journal of Gastroenterology, 28(39), 5750–5763. -
Subcutaneous Sweet Syndrome Successfully Treated With Ustekinumab in a Patient With Ulcerative Colitis.
Hu, K. A., Shen, J., Rieger, K., Wei, M. T., & Gubatan, J. (2022). Subcutaneous Sweet Syndrome Successfully Treated With Ustekinumab in a Patient With Ulcerative Colitis. ACG Case Reports Journal, 9(11), e00881. -
Dietary Exposures and Interventions in Inflammatory Bowel Disease: Current Evidence and Emerging Concepts.
Gubatan, J., Kulkarni, C. V., Talamantes, S. M., Temby, M., Fardeen, T., & Sinha, S. R. (2023). Dietary Exposures and Interventions in Inflammatory Bowel Disease: Current Evidence and Emerging Concepts. Nutrients, 15(3). -
Editorial: treat-to-target in ulcerative colitis clinical management-a small price to pay?
Barber, G. E., & Gubatan, J. (2023). Editorial: treat-to-target in ulcerative colitis clinical management-a small price to pay? Alimentary Pharmacology & Therapeutics, 57(5), 569–570. -
Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis.
Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, O. H., & Seidelin, J. B. (2023). Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis. EClinicalMedicine, 57, 101866. -
Case Series of Precision Delivery of Methylprednisolone in Pediatric Inflammatory Bowel Disease: Feasibility, Clinical Outcomes, and Identification of a Vasculitic Transcriptional Program.
Levitte, S., Yarani, R., Ganguly, A., Martin, L., Gubatan, J., Nadel, H. R., … Thakor, A. S. (2023). Case Series of Precision Delivery of Methylprednisolone in Pediatric Inflammatory Bowel Disease: Feasibility, Clinical Outcomes, and Identification of a Vasculitic Transcriptional Program. Journal of Clinical Medicine, 12(6). -
Small bowel adenocarcinoma in neoterminal ileum in setting of stricturing Crohn's disease: A case report and review of literature.
Karthikeyan, S., Shen, J., Keyashian, K., & Gubatan, J. (2023). Small bowel adenocarcinoma in neoterminal ileum in setting of stricturing Crohn's disease: A case report and review of literature. World Journal of Clinical Cases, 11(9), 2021–2028. -
Selective JAK1 inhibitors for the treatment of inflammatory bowel disease.
Nielsen, O. H., Boye, T. L., Gubatan, J., Chakravarti, D., Jaquith, J. B., & LaCasse, E. C. (2023). Selective JAK1 inhibitors for the treatment of inflammatory bowel disease. Pharmacology & Therapeutics, 108402. -
Effectiveness of Non-Budesonide Therapies in Management of Microscopic Colitis: A Systematic Review and Meta-analysis.
Rehde, A., Hendel, S. K., Juhl, C. B., Gubatan, J., & Nielsen, O. H. (2023). Effectiveness of Non-Budesonide Therapies in Management of Microscopic Colitis: A Systematic Review and Meta-analysis. Drugs. -
Kinase Signaling in Colitis-Associated Colon Cancer and Inflammatory Bowel Disease.
Temby, M., Boye, T. L., Hoang, J., Nielsen, O. H., & Gubatan, J. (2023). Kinase Signaling in Colitis-Associated Colon Cancer and Inflammatory Bowel Disease. Biomolecules, 13(11). -
Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation.
Nielsen, O. H., Gubatan, J. M., Kolho, K.-L. L., Streett, S. E., & Maxwell, C. (2024). Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation. Lancet (London, England). -
Some Drugs Have Two Faces: Paradoxical Colitis in a Patient with Psoriatic Arthritis Previously Treated with Etanercept and IL-17 Inhibitors.
Huynh, S., Achalu, S., Berry, R., Lin, J., Wang, C. X., Gubatan, J., & Cheng, A. G. (2024). Some Drugs Have Two Faces: Paradoxical Colitis in a Patient with Psoriatic Arthritis Previously Treated with Etanercept and IL-17 Inhibitors. Digestive Diseases and Sciences. -
Gut Microbiome and Disorders of the Gastrointestinal Tract.
Hammerhøj, A., Gubatan, J. M., & Nielsen, O. H. (2024). Gut Microbiome and Disorders of the Gastrointestinal Tract. Microorganisms, 12(3). -
INTEGRATION OF SPATIAL MULTI-OMIC IMAGING WITH MASS CYTOMETRY IDENTIFIES RARE CELL SUBSETS IN ULCERATIVE COLITIS
Holman, D., Rogalla, S., Gubatan, J. M., Rubin, S. J., & Ferenc, M. (2022). INTEGRATION OF SPATIAL MULTI-OMIC IMAGING WITH MASS CYTOMETRY IDENTIFIES RARE CELL SUBSETS IN ULCERATIVE COLITIS. GASTROENTEROLOGY. W B SAUNDERS CO-ELSEVIER INC. -
ANTI-TNF BIOLOGICS AND 5-YEAR RISK OF EXTRAINTESTINAL MANIFESTATIONS OF INFLAMMATORY BOWEL DISEASE: A PROPENSITY-MATCHED NATIONAL DATABASE COHORT ANALYSIS
Gubatan, J. M., Kuswanto, W., Gombar, S., Peach, S. E., Limsui, D., Sinha, S. R., & Keyashian, K. (2022). ANTI-TNF BIOLOGICS AND 5-YEAR RISK OF EXTRAINTESTINAL MANIFESTATIONS OF INFLAMMATORY BOWEL DISEASE: A PROPENSITY-MATCHED NATIONAL DATABASE COHORT ANALYSIS. GASTROENTEROLOGY. W B SAUNDERS CO-ELSEVIER INC. -
SINGLE-CELL IMMUNE PROFILING AND REPERTOIRE ANALYSIS OF CONVALESCENT PATIENTS WITH INFLAMMATORY BOWEL DISEASE AND SARS-COV-2 ANTIBODY RESPONSE
Gubatan, J. M., Singh, G., Balabanis, T., Patel, A., Sharma, A., Ji, A. R., … Habtezion, A. (2022). SINGLE-CELL IMMUNE PROFILING AND REPERTOIRE ANALYSIS OF CONVALESCENT PATIENTS WITH INFLAMMATORY BOWEL DISEASE AND SARS-COV-2 ANTIBODY RESPONSE. GASTROENTEROLOGY. W B SAUNDERS CO-ELSEVIER INC. -
Differential expression of small bowel TGFß1 and TGFß3 characterizes intestinal strictures in patients with fibrostenotic Crohn's disease.
Levitte, S., Khan, I., Iyahen, V., Ziai, J., Gubatan, J., Sheng, R., … Keir, M. (2024). Differential expression of small bowel TGFß1 and TGFß3 characterizes intestinal strictures in patients with fibrostenotic Crohn's disease. Histochemistry and Cell Biology. -
Influence of vitamin D receptor signaling and vitamin D on colonic epithelial cell fate decisions in ulcerative colitis.
Kellermann, L., Hansen, S. L., Maciag, G., Granau, A. M., Johansen, J. V., Teves, J. M., … Nielsen, O. H. (2024). Influence of vitamin D receptor signaling and vitamin D on colonic epithelial cell fate decisions in ulcerative colitis. Journal of Crohn's & Colitis. -
Gut microbiome-based therapeutics in inflammatory bowel disease
Hu, K. A., & Gubatan, J. (2023). Gut microbiome-based therapeutics in inflammatory bowel disease. CLINICAL AND TRANSLATIONAL DISCOVERY, 3(2). -
Network meta-analysis: Comparative onset of early effect of biologics and small molecules in moderately to severely active luminal Crohn's disease.
Attauabi, M., Steenholdt, C., Poulsen, A., Gubatan, J., Burisch, J., Haagen Nielsen, O., & Seidelin, J. B. (2024). Network meta-analysis: Comparative onset of early effect of biologics and small molecules in moderately to severely active luminal Crohn's disease. Alimentary Pharmacology & Therapeutics. -
Artificial intelligence and machine learning technologies in ulcerative colitis.
Kulkarni, C., Liu, D., Fardeen, T., Dickson, E. R., Jang, H., Sinha, S. R., & Gubatan, J. (2024). Artificial intelligence and machine learning technologies in ulcerative colitis. Therapeutic Advances in Gastroenterology, 17, 17562848241272001. -
Immune effector cell-associated enterocolitis following chimeric antigen receptor T-cell therapy in multiple myeloma.
Fortuna, G. G., Banerjee, R., Savid-Frontera, C., Song, J., Morán-Segura, C. M., Nguyen, J. V., … Hansen, D. K. (2024). Immune effector cell-associated enterocolitis following chimeric antigen receptor T-cell therapy in multiple myeloma. Blood Cancer Journal, 14(1), 180. -
Immunogenicity of Therapeutic Antibodies Used for Inflammatory Bowel Disease: Treatment and Clinical Considerations.
Nielsen, O. H., Hammerhøj, A., Ainsworth, M. A., Gubatan, J., & D'Haens, G. (2024). Immunogenicity of Therapeutic Antibodies Used for Inflammatory Bowel Disease: Treatment and Clinical Considerations. Drugs. -
A Similar Mutation in the AAUU-Rich Elements of the Mouse TNF Gene Results in a Distinct Ileocolitic Phenotype: A New Strain of TNF-Overexpressing Mice.
Chilukuri, A., Kim, M., Mitra, T., Gubatan, J. M., Urrete, J., Saxon, L. D., … Rivera-Nieves, J. (2025). A Similar Mutation in the AAUU-Rich Elements of the Mouse TNF Gene Results in a Distinct Ileocolitic Phenotype: A New Strain of TNF-Overexpressing Mice. Inflammatory Bowel Diseases.
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Hemorrhage from Extra-Antral Gastric Antral Vascular Ectasia in a Patient with Duodenal Heterotopic Gastric Mucosa.
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Practice Locations
SHC- Gastro (300 Pasteur) Stanford, CA
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Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Patient Reviews
(74 reviews)
I appreciated his knowledge & recommendations.
Dr. Gubatan is a nice and caring doctor. I also feel comfortable to have him as a doctor because he cares for me as a person and as a patient.
Dr. Gubatan listened and asked good questions.
dr gubatan is great!!!
Dr. Gubatan was very cordial and attentive. He had thoroughly reviewed my case and I felt very valued and attended to. I am very confident in the care of Dr. Gubatan!
dr. gubatan is amazing!
He is very personable and friendly, including being an excellent physician.
Dr. Gubatan has always been very caring and thorough. I appreciate his patience with me and his willingness to help!
Very informed, caring and flexible.
Absolutely, Dr. Gubatan is the best!
I would like to say thank you for helping my grandson. We really appreciate it!
great doctor.
He was great!!
He is a great doctor. I am so happy that I found him and he has been my doctor for the last year and a half. We takes everything that I have to say into account and goes above and beyond to address every symptom. I like that he is proactive and attentive. I hope to be his patient for as long as possible.
Dr Gubatan was articulate, clear and spoke in enough layman's terms so I could understand his prognosis and future treatment plans.
He and his intern Dr RUbin were both affable and easy to work with.
I appreciate his professionalism and ability to make a potentially embarrassing topic comfortable
Dr. Gubatan is awesome!
Dr. John Gubatan takes time to answer your questions and explains everything in terms that are easy to understand. He is very knowledgeable.
He's an excellent doctor. He took time to answer my questions and invited me to participate in decision making.
Very excellent and very good Doctor.
I feel very fortunate to have John Gubatan as my gastroenterologist.
Competent & caring.
Dr Gubatan was very courteous, helpful and knowledgeable. I enjoyed talking to him.
Thank you for making it easy to talk with you about my procedure and the future direction for my treatment
I am very happy with my Dr, he is knowledgeable and empathetic
I appreciate the doctor's approach. He is warm and always seems caring. He is prepared and I appreciate that.
Dr. Gubatan is an excellent doctor. He was very prepared with all the information about my medical history. He was easy to talk to and very thorough. I would highly recommend him. I am so happy to have him as my doctor. I feel like he is going to do everything he can to help me to get back to good GI health.
I enjoyed & got a lot out of our appt.
He was very easy to speak with and very reassuring
Empathetic and patient
Dr. Gubatan and his resident were very friendly and supportive, answered all my questions, and outlined a clear and comprehensive care plan.
Incredible doctor. Treated me with respect. Knowledgeable, compassionate, and validating
I am grateful to have Dr. Gubatan on my care team. He is patient, attentive, and sympathetic. I trust his expertise about my condition and anticipate a successful outcome after his treatment.
Dr. Gubatan has been a pleasure to work with. He immediately addressed my problem at the outset, provided test result commentaries as needed and set expectations of my progress. He and his staff have been responsive to all of my questions and concerns. He is cordial, informative and set expectations for me of what my treatment would consist of. I could not be happier with him and of the results he made possible for me.
Very friendly & makes the patient feel relax.
Wow amazing how thorough and informative Dr Gubatan is
Dr Gubatan did a fabulous job explaining my problem with Crohn's disease, Dr ordered a couple of tests for me. Felt very comfortable talking with Dr Gubatan.
I appreciate his kind words and patience. I felt very fortunate to have him as my doctor.
great visit. five stars every time.
Outstanding physician
Dr Gubatan is a wonderful doctor. He is very competent, thorough, and very friendly.
I’m very happy with the care I received and would definitely recommend this care provider.
Very helpful and knowledgeable doctor. Very professional support staff.
Dr. Gubatan has been wonderful so far and so has the whole care team! I have struggled for years to find the right care system and I am grateful for this team and clinic.
Very personable and take the time to incorporate the patient into the process.
Dr. Gubatan is so helpful and with the best advice- Thank you so much!
Dr Gubatan really listens to my concerns and provides real solutions.
Dr Guantanamo was great. Patient and gave me as much time as I needed.
He was knowledgeable and had read my history prior to my visit. He explained everything and asked me if I had questions. He was compassionate and assured me he would help restore my health.
He’s the BEST!
He’s a good Doctor ðŸ‘
positive experense
Dr. Hubs tan was great! He is very competent, thorough and kind
Dr. Gubatan was wonderful! He was prepared, he listened to me and he seemed confident that there was a plan to assess and treat my Crohn's disease. He validated the experiences that I had that led me to the Stanford referral and gave me a clear idea of what we could do next. I was very relieved after my visit because I have spent nearly a year suffering with no solutions. I am grateful to have a new plan!
Great! He was friendly and explained everything thoroughly.
Dr. Gubatan is clear, considerate and organized. In addition he has a very nice and caring way about him, which is a bonus.
Dr. Gubatan was the most professional doctor I have ever been to. His treatment plan is extensive and he seems to really care about his patients.
Very good
He was very understanding and very thorough.
One of the best medical interviews I have enjoyed during my 81 years!
Very friendly, knowledgable, articulate, and sensible. Recommend highly
Dr. Gubatan is excellent!
Buen doctor porque escucha las preguntas que se le asen y las responde bien
Friendly, good at explaining and made sure I understood. Concerned and happy to help me. I believe he is a very good doctor.
Great conversation, informative and great listener
excellent doctor
excellent care
listens very well
cares about solving my issues
one of the best doctors I've ever worked with
Very friendly and throw . I'm excited to be in his care !
visit on time receptionists friendly and the MD took his time explaining and and answering my questions all done in a professional manner .
Thanks for his listening
Excellent care and very knowledgeable.
The doctor was clear to explain any questions I needed to ask. I felt heard and am pleased that I am now apart of his patient team. He was respectful, clear to explain any questions I presented, and felt comforted by his delivery to his professional support.
My doctor was so great in explaining everything to me. He answered all my concerns. Very very good Dr. John Gubatan. And thank you so much for taking care of me ðŸ™
He was someone who finally gave me hope.
Dr Gubatan was great! He listened to me & gave me ways to help take care of my problem.
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