Publications

• Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice
  Aszterbaum, M., Epstein, J., Oro, A., Douglas, V., LeBoit, P. E., Scott, M. P., & Epstein, E. H. (1999). Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. NATURE MEDICINE, 5(11), 1285–1291.
• Hair cycle regulation of Hedgehog signal reception
  Oro, A. E., & Higgins, K. (2003). Hair cycle regulation of Hedgehog signal reception. DEVELOPMENTAL BIOLOGY, 255(2), 238–248.
• Laminin-10 is crucial for hair morphogenesis
  Li, J., Tzu, J., Chen, Y., Zhang, Y. P., Nguyen, N. T., Gao, J., … Marinkovich, M. P. (2003). Laminin-10 is crucial for hair morphogenesis. EMBO JOURNAL, 22(10), 2400–2410.
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• Mammalian variations on a theme: a Smo and Sufu surprise Oro, A. E. (2006). Mammalian variations on a theme: a Smo and Sufu surprise. DEVELOPMENTAL CELL, 10(2), 156–158.
  
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• The primary cilia, a 'Rab-id' transit system for hedgehog signaling Oro, A. E. (2007). The primary cilia, a 'Rab-id' transit system for hedgehog signaling. CURRENT OPINION IN CELL BIOLOGY, 19(6), 691–696.
  
• A new role for an old friend: NFAT and stem cell quiescence Oro, A. E. (2008). A new role for an old friend: NFAT and stem cell quiescence. CELL STEM CELL, 2(2), 104–106.
  
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• Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis Gao, J., DeRouen, M. C., Chen, C.-H., Nguyen, M., Nguyen, N. T., Ido, H., … Marinkovich, M. P. (2008). Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. GENES & DEVELOPMENT, 22(15), 2111–24.
  
• The Primary Cilium: A Small Yet Mighty Organelle DeRouen, M. C., & Oro, A. E. (2009). The Primary Cilium: A Small Yet Mighty Organelle. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 129(2), 264–265.
  
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• In Vivo Imaging of Human and Mouse Skin with a Handheld Dual-Axis Confocal Fluorescence Microscope Ra, H., Piyawattanametha, W., Gonzalez-Gonzalez, E., Mandella, M. J., Kino, G. S., Solgaard, O., … Contag, C. H. (2011). In Vivo Imaging of Human and Mouse Skin with a Handheld Dual-Axis Confocal Fluorescence Microscope. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 131(5), 1061–66.
  
• Role of the basement membrane zone in skin development. Oro, A. E. (2008). Role of the basement membrane zone in skin development. Journal of Investigative Dermatology, 128(E2), E11–2.
  
• Cell Migration: GSK3 beta Steers the Cytoskeleton's Tip Yucel, G., & Oro, A. E. (2011). Cell Migration: GSK3 beta Steers the Cytoskeleton's Tip. CELL, 144(3), 319–321.
  
• SnapShot: Hair Follicle Stem Cells Woo, W.-M., & Oro, A. E. (2011). SnapShot: Hair Follicle Stem Cells. CELL, 146(2), 334–U159.
  
• Neuropilins are positive regulators of Hedgehog signal transduction Hillman, R. T., Feng, B. Y., Ni, J., Woo, W.-M., Milenkovic, L., Gephart, M. G. H., … Scott, M. P. (2011). Neuropilins are positive regulators of Hedgehog signal transduction. GENES & DEVELOPMENT, 25(22), 2333–2346.
  
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• Hedgehog pathway inhibition and the race against tumor evolution Atwood, S. X., Chang, A. L. S., & Oro, A. E. (2012). Hedgehog pathway inhibition and the race against tumor evolution. JOURNAL OF CELL BIOLOGY, 199(2), 193–197.
  
• GLI activation by atypical protein kinase C ?/? regulates the growth of basal cell carcinomas. Atwood, S. X., Li, M., Lee, A., Tang, J. Y., & Oro, A. E. (2013). GLI activation by atypical protein kinase C ?/? regulates the growth of basal cell carcinomas. Nature, 494(7438), 484–488.
  
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• Hedgehog/patched signaling in animal development and disease Scott, M. P., Goodrich, L. V., Higgins, K. M., Johnson, R. L., Milenkovic, L., & Oro, A. E. (1997). Hedgehog/patched signaling in animal development and disease. FASEB JOURNAL, 11(9), A1302–A1302.
  
• Induction of features of basal cell epithelioma in transgenic human skin expressing sonic Hedgehog in vivo. Fan, H., Oro, A. E., Scott, M. P., & Khavari, P. A. (1997). Induction of features of basal cell epithelioma in transgenic human skin expressing sonic Hedgehog in vivo. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 108(4), 38–38.
  
• Hedgehog pathway inhibition and the race against tumor evolution Atwood, S. X., Chang, A. L. S., & Oro, A. E. (2013). Hedgehog pathway inhibition and the race against tumor evolution. JOURNAL OF CELL BIOLOGY, 45–49.
  
• A perivascular stem cell niche in the hair follicle Xiao, Y., Woo, W., Terunuma, A., Oro, A. E., Vogel, J. C., & Brownell, I. (2012). A perivascular stem cell niche in the hair follicle. Presented at the 75th Annual Meeting of the Society-for-Investigative-Dermatology, RALEIGH,NC: NATURE PUBLISHING GROUP.
  
• Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4 Gonzalez-Quevedo, R., Shoffer, M., Horng, L., & Oro, A. E. (2005). Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 124(4), A103–A103.
  
• MOLECULAR ANALYSIS OF THE INHERITANCE AND STABILITY OF THE MITOCHONDRIAL GENOME OF AN INBRED LINE OF MAIZE Oro, A. E., Newton, K. J., & Walbot, V. (1985). MOLECULAR ANALYSIS OF THE INHERITANCE AND STABILITY OF THE MITOCHONDRIAL GENOME OF AN INBRED LINE OF MAIZE. THEORETICAL AND APPLIED GENETICS, 70(3), 287–293.
  
• Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing Whyte, J. L., Smith, A. A., Liu, B., Manzano, W. R., Evans, N. D., Dhamdhere, G. R., … Helms, J. A. (2013). Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing. PLOS ONE, 8(10).
  
• Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing ß-Catenin. Yucel, G., Van Arnam, J., Means, P. C., Huntzicker, E., Altindag, B., Lara, M. F., … Oro, A. E. (2014). Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing ß-Catenin. Stem Cells , 32(1), 85–92.
  
• "Atypical" regulation of Hedgehog-dependent cancers. Atwood, S. X., & Oro, A. E. (2014). "Atypical" regulation of Hedgehog-dependent cancers. Cancer Cell, 25(2), 133–134.
  
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• Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition. Tang, Y., Gholamin, S., Schubert, S., Willardson, M. I., Lee, A., Bandopadhayay, P., … Cho, Y.-J. (2014). Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition. Nature Medicine, 20(7), 732–740.
  
• Advanced treatment for basal cell carcinomas. Atwood, S. X., Whitson, R. J., & Oro, A. E. (2014). Advanced treatment for basal cell carcinomas. Cold Spring Harbor Perspectives in Medicine, 4(7).
  
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• Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa Sebastiano, V., Zhen, H. H., Derafshi, B. H., Bashkirova, E., Melo, S. P., Wang, P., … Oro, A. E. (2014). Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. SCIENCE TRANSLATIONAL MEDICINE, 6(264).
  
• Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration Woo, W.-M., Atwood, S. X., Zhen, H. H., & Oro, A. E. (2013). Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (72).
  
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• Rolling the Genetic Dice: Neutral and Deleterious Smoothened Mutations in Drug-Resistant Basal Cell Carcinoma. Atwood, S. X., Sarin, K. Y., Li, J. R., Yao, C. Y., Urman, N. M., Chang, A. L. S., … Oro, A. E. (2015). Rolling the Genetic Dice: Neutral and Deleterious Smoothened Mutations in Drug-Resistant Basal Cell Carcinoma. Journal of Investigative Dermatology, 135(8), 2138–2141.
  
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• Role of the Basement Membrane Zone in Skin Development. Oro, A. E. (2008). Role of the Basement Membrane Zone in Skin Development. Journal of Investigative Dermatology, 128, E11–2.
  
• Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth. Smith, A. A., Li, J., Liu, B., Hunter, D., Pyles, M., Gillette, M., … Helms, J. A. (2016). Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth. Journal of Investigative Dermatology, 136(8), 1549–1558.
  
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• Soil Primes the Seed: Epigenetic Landscape Drives Tumor Behavior. Whitson, R. J., & Oro, A. E. (2017). Soil Primes the Seed: Epigenetic Landscape Drives Tumor Behavior. Cell Stem Cell, 20(2), 149–150.
  
• Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions Urman, N. M., Mirza, A., Atwood, S. X., Whitson, R. J., Sarin, K. Y., Tang, J. Y., & Oro, A. E. (2016). Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions. PLOS ONE, 11(12).