Dr. John Clarke recently joined the Gastroenterology & Hepatology Division at Stanford University as Director of the Esophageal Program. He previously spent 17 years in Baltimore, including 9 years on the faculty at Johns Hopkins University where he was an Associate Professor and at various times Director of Esophageal Motility, Director of Gastrointestinal Motility, Clinical Director of the Johns Hopkins Center for Neurogastroenterology, and Clinical Director of the Gastroenterology & Hepatology Division at Johns Hopkins Bayview Medical Center.

His career has combined research, education and clinical care. His clinical areas of expertise include achalasia, dysphagia, eosinophilic esophagitis, esophageal dysmotility, gastroesophageal reflux disease, gastroparesis, GI-manifestations of scleroderma and GI dysmotility. While at Johns Hopkins University, he was inducted into The Miller-Coulson Academy for Clinical Excellence, an institutional honor society for master clinicians at the time limited to 50 members across the entire university.

From an education standpoint, he has lectured in over a dozen countries, authored over 25 textbook chapters and serves on the educational affairs committee of the American College of Gastroenterology. He has also won several major teaching awards, including The Johns Hopkins University Alumni Association Award for Excellence in Teaching, given to one faculty member per year in the entire School of Medicine.

His research has focused on optimization and characterization of diagnostic studies to evaluate motility disorders, as well the relationship between therapeutic endoscopic techniques and treatment of motility disorders. He was an investigator on the NIH Gastroparesis Consortium and is also a former recipient of the AGA Don Castell Award.

Professional Summary

Professional Education
  • Board Certification: American Board of Internal Medicine, Gastroenterology (2007)
  • Fellowship: Johns Hopkins University Dept of Gastroenterology (2007) MD
  • Board Certification: American Board of Internal Medicine, Internal Medicine (2002)
  • Residency: Johns Hopkins Hospital Internal Medicine Residency (2002) MD
  • Medical Education: Columbia University College of Physicians and Surgeons (1999) NY

Honors & Awards
  • Award for Excellence in Teaching, John Hopkins University Alumni Association (2015)

Administrative Appointments
  • Director, Esophageal Program, Stanford Medicine (2016 - Present)


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Practice Locations

Digestive Health Center in Redwood City Redwood City, CA
Redwood City, CA

420 Broadway Street, Pavilion D, 2nd Floor

Redwood City , CA 94063

(650) 736-5555

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Esophagus Center Redwood City, CA
Redwood City, CA

420 Broadway Street, Pavilion D, 2nd Floor

Redwood City , CA 94063

(650) 736-5555

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Amyloid Center Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 725-6186

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General Endoscopy Redwood City, CA
Redwood City, CA

420 Broadway Street, Pavilion D, 2nd Floor

Redwood City , CA 94063

(650) 736-5555

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Patient Ratings

(9 Ratings)

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Patient Reviews

(88 reviews)

After 2 years, Dr. Clarke has yet to figure out what's wrong with me.
Dr. John Clarke is amazingly good - Both in "bedside manner" and understanding the medical issues and explaining them in an honest manner to the patient.
The best doctor ever!
Dr. Clarke is an excellent care giver, very professional and caring.\
amazing care, awesome Doctor. things are always explained in a way I can understand. any questions or concerns I have are always addressed.
Dr. Clarke is the best doctor that performed my colonoscopy procedure.
Genuinely concerned included me in decisions about my care. was not rushed
Best doctor ever! Friendly, listens explains any concerns. Have total trust in Dr. Clarke. Only wish there were more doctors like him.
was impressed with Dr. Clark
Dr. Clarke is fantastic and has been an exemplary example of the professionalism and world-class level of care provided by Stanford.
It was a pleasure to talk with a physician who is not only kind and considerate, but who clearly knows your situation and how best to deal with it.
Dr. Clark does an excellent job. Explains everything clearly -
Dr. Clarke is a very kind, caring and compassionate doctor. He is extremely knowledgeable in Motility and Scleroderma GI involvement which is mandatory for a patient such as myself. I feel very confident in his treatments and advice.
Dr. Clark "ROCKS." Dr. Clark - 1:1 meeting.
Dr. Clarke is always very attentive and puts you at ease.
I'm not really one of those people who marks very good for everything, but this just so happens to be the truth. This provider speaks to you as an equal, with thorough amount of in-depth information so you can make good decisions for yourself about your care. Really the best provider I have ever seen for any issue or trouble.
Dr. Clark is an amazing, caring, and knowledgeable doctor.
Dr. Clarke is amazing! I've been very ill for a long time and for the first time I've been given hope. He is very knowledgeable, caring, and thorough. I have not been this impressed with a care provider before. I am grateful to be under his care.
Dr. Clarke performed his duties above and beyond. I have utmost confident in his medical abilities.
Excellent providers. Did a wonderful job in answering all my questions.
Dr. Clarke is an exceptionally great specialist. He is also a great human being with understanding compassion and patience.
Dr. Clarke was extremely knowledgeable about my symptoms and conditions. He put me at ease with treatment options and further care. He was not in any rush and I appreciated the time and thoroughness he gave me.
Dr Clarke is the best all around!
Although he was running quite late due to the crisis, he did not make us feel hurried and answered all questions asked of him.
shared with neighbors ,friends and family what a good experience we had . Neighbor has already called and schedule a visit with the provider.
Dr. Clarke is an excellent physician.
MD and resident & intern were great. Stanford itself, though, always leaves much to be desired where support staff and such are concerned.
Dr. Clarke is wonderful. Kind and considerate of my issues and general health! He is reassuring and gives me hope.
As much as the dr. as his personnel are very nice and humanitarian.
I was pleased with the care I received. The doctor answered all questions and addressed my concerns. He was patient and did not make me feel rushed. I appreciated the amount of time he dedicated to my appointment.
Even as we were late he spent time with us as needed.
Clarke and his PAs have been great. We are working through a plan and he's been supportive of my desire and needs. I've already recommended him to others.
Dr. Clarke was very professional & informative.
Dr. Clarke is a very patient doctor.
I know that my mother is in very good hands with Dr. Clarke. He takes the time to listen to her. He asks for her opinion about other care options and is very empathetic and concerned for her health. Her health is what it is but is really helps her to deal with her issues knowing that Dr. Clarke continues to try and provide relief. He also advises of new and upcoming medications that may assist her. We are very grateful to Dr. Clarke for his care of my mother.
Best GI doc I've seen.
The doctor did NOT review my history (medical records) and I had to start again - Very unproductive.
Dr.John Clarke is very personable, helpful and knowledgeable. I am getting to know him more and as of now, I feel comfortble with his approaches.
This is when it gets GOOD!! Dr. Clarke is amazing, kind and spends a lot of time!! Dr. Alexander Podbody is amazing. He has qualities that will make him a successful doctor!!!! Both have great "beside manner."
The problem is a plan is created and then never executed. Also there have been a few times I have messaged using the online portal and no one responds.
I've never spent so much time with a gastroenterologist. Dr. Clark didn't seem to be in a rush (a common experience I've had in the past), and used the information from my esophagus biopsy (done in 2017) to inform me of another illness that I didn't know I had and that was causing a lot of my symptoms. This information and his advice have already made a difference.
Dr Clarke has always had a listening ear and provides a great bedside manner. his knowledge is vast, but he's also willing to admit when things are difficult. he's a wonderful doctor!
Dr. Clarke is a excellent doctor. He is caring and helpful.
Dr. Brian-Clark is fantastic, one of the finest physicians I have ever dealt with. Thank you!
I had a wonderful experience with him. He was very friendly and understanding and accommodating to my needs.
Dr. Clarke is patient, friendly, knowledgable and professional. THANK YOU so much Dr. Clarke.
This is my first visit... overall experience with doctor was good. follow ups and scheduling is pathetic with his staff.
Dr. Clarke epitomizes what an outstanding GI Doctor ought to be. Please keep him happy so he'll stay put.
The care providers were very patient
Dr. Clarke gave me excellent care, took the time to walk me through my questions.
Dr. Clarke and his associate doctor really listened to all my concerns. Both doctors took their time and never rushed me. It was an extremely positive first experience.
Doctor Clarke was very kind I liked him. Most doctors I deal with are arrogant he was not.
Excellent provider
Based on similar Drs I have visited in the immediate area Dr Clarke is hands down the most courteous and professional Dr I have found.
Very good!
Dr. J. O. Clarke was very understanding and answered all my questions. He offered solutions that made sense and overall I felt confident that I will get better.
Dr. Clarke was wonderful and made me feel very comfortable.
These comments refer to Dr. Clarke. I was somewhat concerned that he thought my connective tissue disorder (EDS) didn't apply to internal organs, muscles and viscera--only to skin and joints. I was pleased that he took note with my concern and correction of this perception. Overall, Dr. Clarke was a very kind and knowledgable and a good listener. I wasn't expecting him to suggest P.O.E.M. and had prepped my questions for dilatation, and so afterwards, thought of questions about P.O.E.M. I should have asked...
Excellent service from Dr. John.
Both NP and doctor were very informative and helpful. Great bedside manner!
Dr. Clarke is a very good & caring doctor.
I would recommend my care provider to my family, friends or anyone that I meet.
Dr. Clarke is very personable responsive to my needs and issues good listener and extremely well organized with a PLAN at follow up after endo/colo.
Dr. Clarke is excellent. Very knowledgeable yet humble. He listens very carefully to his patients. Best GI dr. I had every have.
I have already recommended Dr. Clarke to others.
Dr. Clarke seemed to care.
Dr. Clarke is the best.
Again really liked Dr. John Clarke. He's a caring and thoughtful Doctor!
He communicates his expertise in a way I understand and lets me know his reasoning for his decisions.
Dr. Clarke is and patient. My health issues are unusual and complicated and I have really appreciated his persistence in trying to get to the bottom of the problem even though several tests have not yielded any easy answers.
O'Brien is the best GI Doc I've ever seen; and I've seen many. He's smart, keeps up on latest research, friendly, and takes the time to brainstorm options with me.
This was my first time seeing this dr. He explained things very well.
Has better insights than other G.I. dr.'s I have seen.
I find it very easy and pleasant to discuss my care with Dr. Clarke. I have great confidence in him.
A most reassuring experience.
Very caring and thoughtful.
Easily the best doctor I have seen. Very precise, helpful. Wish there were more such doctors. When the doctor is confident, the patient feels confident. Dr. Clarke takes the time to answer questions. I trust him.
So thankful to have Dr. Clarke caring for me.
I was very impressed that he did some research/reading about my issues prior to coming in to the room and then told me about what he had learned. Taking that extra step/time did not go unnoticed
Dr. Clarke is amazing! He is very thorough and open to my questions and requests. I have seen several Gastroenterologists and he has been the one to give me the most hope.
Dr. Clarke is awesome.
Dr. O'Brien reviewed my medications and determined that some were those he would prescribe, but possibly in different doses. We agreed that if my symptoms increased again, I would contact him.
Dr. Cooke is a caring, patient, supportive doctor.

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