Professional Summary
Education & Certifications
- Fellowship: UCLA Medical Center Obstetrics and Gynecology Fellowships (2005) CA
- Residency: UCLA Medical Center Obstetrics and Gynecology Residency (1999) CA
- Medical Education: University of Heidelberg (1989) Germany
- Board Certification: American Board of Obstetrics and Gynecology, Gynecologic Oncology (2008)
- Board Certification: American Board of Obstetrics and Gynecology, Obstetrics and Gynecology (2006)
- PhD, University of California, Los Angeles, Molecular Biology (2003)
- Residency: Ludwig Maximillians University (1992) Germany
Honors & Awards
- American Association of Cancer Research Outstanding Poster Award, Toronto, Canada, American Association of Cancer Research, Toronto, Canada (1995)
- OB/GYN Resident Teaching Award, University of California, Los Angeles (2008)
- Outstanding Podium Presentation Award, National Gynecologic Oncology Fellow’s Forum (2004)
- STOP Cancer Career Development Award, STOP Cancer (2008)
- Teaching Award, National Council on Resident Education in Obstetrics and Gynecology (2007)
Memberships
- Member, Society of Pelvic Surgeons (2016 - Present)
- Member, American Association of Cancer Research (1996 - Present)
- Member, American Gynecological and Obstetrical Society (2016 - Present)
- Member, Society of Gynecologic Investigations (2000 - Present)
- Member, American Society of Gene Therapy (2000 - Present)
- Member, Society of Gynecologic Oncology (2005 - Present)
- Member, Gynecologic Oncology Group (2005 - Present)
Administrative Appointments
- Director, Mary Lake Polan Gynecologic Oncology Research Laboratory (2013 - Present)
- Director, Stanford Gynecologic Oncology Clinical Care Program (2013 - Present)
- Director, Stanford Obstetrics and Gynecology, Division of Gynecologic Oncology (2013 - Present)
- Director, Stanford Clinical Research Group for Gynecologic Cancer Trials (2014 - Present)
- Director, Stanford Gynecologic Oncology Fellowship (2016 - Present)
Publications
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IL-2 plasmid therapy of murine ovarian carcinoma inhibits the growth of tumor ascites and alters its cytokine profile
Horton, H. M., Dorigo, O., Hernandez, P., Anderson, D., Berek, J. S., & Parker, S. E. (1999). IL-2 plasmid therapy of murine ovarian carcinoma inhibits the growth of tumor ascites and alters its cytokine profile. JOURNAL OF IMMUNOLOGY, 163(12), 6378–6385. -
A radical debulking of leiomyomatosis peritonealis disseminata from a colonic obstruction: A case report and review of the literature
Ghosh, K., Dorigo, O., Bristow, R., & Berek, J. (2000). A radical debulking of leiomyomatosis peritonealis disseminata from a colonic obstruction: A case report and review of the literature. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 191(2), 212–215. -
Specific keynote: Immunological therapy for ovarian cancer
Berek, J. S., Dorigo, O., Schultes, B., & Nicodemus, C. (2003). Specific keynote: Immunological therapy for ovarian cancer. GYNECOLOGIC ONCOLOGY, 88(1), S105–S109. -
Gene therapy for ovarian cancer: Development of novel treatment strategies
Dorigo, O., & Berek, J. S. (1997). Gene therapy for ovarian cancer: Development of novel treatment strategies. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 7(1), 1–13. -
CA125: Megadaltons of novel opportunities
Dorigo, O., & Berek, J. S. (2007). CA125: Megadaltons of novel opportunities. GYNECOLOGIC ONCOLOGY, 104(3), 505–507. -
HER-2/neu targeting for recurrent vulvar Paget's disease A case report and literature review
Karam, A., Berek, J. S., Stenson, A., Rao, J., & Dorigo, O. (2008). HER-2/neu targeting for recurrent vulvar Paget's disease A case report and literature review. GYNECOLOGIC ONCOLOGY, 111(3), 568–71. -
Personalizing CA125 Levels for Ovarian Cancer Screening
Dorigo, O., & Berek, J. S. (2011). Personalizing CA125 Levels for Ovarian Cancer Screening. CANCER PREVENTION RESEARCH, 4(9), 1356–1359. -
Combination of transforming growth factor beta antisense and interleukin-2 gene therapy in the murine ovarian teratoma model
Dorigo, O., Shawler, D. L., Royston, I., SOBOL, R. E., Berek, J. S., & Fakhrai, H. (1998). Combination of transforming growth factor beta antisense and interleukin-2 gene therapy in the murine ovarian teratoma model. GYNECOLOGIC ONCOLOGY, 71(2), 204–210. -
Development of a novel helper-dependent adenovirus-Epstein-Barr virus hybrid system for the stable transformation of mammalian cells
Dorigo, O., Gil, J. S., Gallaher, S. D., Tan, B. T., Castro, M. G., Lowenstein, P. R., … Berk, A. J. (2004). Development of a novel helper-dependent adenovirus-Epstein-Barr virus hybrid system for the stable transformation of mammalian cells. JOURNAL OF VIROLOGY, 78(12), 6556–66. -
Anti-N-methyl-aspartate receptor encephalitis in identical twin sisters: role for oophorectomy.
Masghati, S., Nosratian, M., & Dorigo, O. (2014). Anti-N-methyl-aspartate receptor encephalitis in identical twin sisters: role for oophorectomy. Obstetrics and Gynecology, 123(2), 433–35. -
Increased risk and pattern of secondary malignancies in patients with invasive extramammary Paget disease.
Karam, A., & Dorigo, O. (2014). Increased risk and pattern of secondary malignancies in patients with invasive extramammary Paget disease. British Journal of Dermatology, 170(3), 661–71. -
Solid pseudopapillary neoplasm, pancreas type, presenting as a primary ovarian neoplasm
Stoll, L. M., Parvataneni, R., Johnson, M. W., Gui, D., Dorigo, O., & Sullivan, P. (2012). Solid pseudopapillary neoplasm, pancreas type, presenting as a primary ovarian neoplasm. HUMAN PATHOLOGY, 43(8), 1339–1343. -
Expression of thyroid transcription factor-1 in normal endometrium is associated with risk of endometrial cancer development
Sullivan, P. S., Maresh, E. L., Seligson, D. B., Habeeb, O., Wadehra, M., Goodglick, L., & Dorigo, O. (2012). Expression of thyroid transcription factor-1 in normal endometrium is associated with risk of endometrial cancer development. MODERN PATHOLOGY, 25(8), 1140–1148. -
Effect of PI3K/Akt Pathway Inhibition-Mediated G(1) Arrest on Chemosensitization in Ovarian Cancer Cells
Fekete, M., Santiskulvong, C., Eng, C., & Dorigo, O. (2012). Effect of PI3K/Akt Pathway Inhibition-Mediated G(1) Arrest on Chemosensitization in Ovarian Cancer Cells. ANTICANCER RESEARCH, 32(2), 445–452. -
Treatment outcomes in a large cohort of patients with invasive Extramammary Paget's disease
Karam, A., & Dorigo, O. (2012). Treatment outcomes in a large cohort of patients with invasive Extramammary Paget's disease. GYNECOLOGIC ONCOLOGY, 125(2), 346–51. -
MMPs in Ovarian Cancer as Therapeutic Targets
Karam, A., & Dorigo, O. (2012). MMPs in Ovarian Cancer as Therapeutic Targets. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 12(7), 764–72. -
Predictors of resolution of complex atypical hyperplasia or grade 1 endometrial adenocarcinoma in premenopausal women treated with progestin therapy
Penner, K. R., Dorigo, O., Aoyama, C., Ostrzega, N., Balzer, B. L., Rao, J., … Holschneider, C. H. (2012). Predictors of resolution of complex atypical hyperplasia or grade 1 endometrial adenocarcinoma in premenopausal women treated with progestin therapy. GYNECOLOGIC ONCOLOGY, 124(3), 542–548. -
Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells
Sharma, S., Santiskulvong, C., Bentolila, L. A., Rao, J., Dorigo, O., & Gimzewski, J. K. (2012). Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 8(5), 757–766. -
Dual targeting of mammalian target of rapamycin and phosphoinositide 3-kinase using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma
Dorigo, O., Santiskulvong, C., Fekete, M., Karam, A., Mulholland, D., Eng, C., & Wu, H. (2009). Dual targeting of mammalian target of rapamycin and phosphoinositide 3-kinase using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma. GYNECOLOGIC ONCOLOGY, 112(2), S9–S10. -
Cisplatin and PI3kinase Inhibition Decrease Invasion and Migration of Human Ovarian Carcinoma Cells and Regulate Matrix-Metalloproteinase Expression
Karam, A. K., Santiskulvong, C., Fekete, M., Zabih, S., Eng, C., & Dorigo, O. (2010). Cisplatin and PI3kinase Inhibition Decrease Invasion and Migration of Human Ovarian Carcinoma Cells and Regulate Matrix-Metalloproteinase Expression. CYTOSKELETON, 67(8), 535–44. -
Robust In Vivo Transduction of a Genetically Stable Epstein-Barr Virus Episome to Hepatocytes in Mice by a Hybrid Viral Vector
Gallaher, S. D., Gil, J. S., Dorigo, O., & Berk, A. J. (2009). Robust In Vivo Transduction of a Genetically Stable Epstein-Barr Virus Episome to Hepatocytes in Mice by a Hybrid Viral Vector. JOURNAL OF VIROLOGY, 83(7), 3249–3257. -
Death from Metastatic Donor-Derived Ovarian Cancer in a Male Kidney Transplant Recipient
Lipshutz, G. S., Mihara, N., Wong, R., Wallace, W. D., Allen-Auerbach, M., Dorigo, O., … Pham, P.-T. T. (2009). Death from Metastatic Donor-Derived Ovarian Cancer in a Male Kidney Transplant Recipient. AMERICAN JOURNAL OF TRANSPLANTATION, 9(2), 428–432. -
Enhanced expression of L9'S mutant alpha 4 nAChR in adult mice increases the loss of midbrain dopaminergic neurons
Schwarz, S. C., Dorigo, O., Labarca, C., Berk, A. J., Lester, H. A., & Schwarz, J. (2004). Enhanced expression of L9'S mutant alpha 4 nAChR in adult mice increases the loss of midbrain dopaminergic neurons. Presented at the 8th International Congress of Parkinsons Disease and Movement Disorders, ROME,ITALY: WILEY-LISS. -
Antigenic and immunologic characterization of an allogeneic colon carcinoma vaccine
Shawler, D. L., Bartholomew, R. M., Garrett, M. A., Trauger, R. J., Dorigo, O., Van Beveren, C., … SOBOL, R. E. (2002). Antigenic and immunologic characterization of an allogeneic colon carcinoma vaccine. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 129(1), 99–106. -
Sensitization of rat glioblastoma multiforme to cisplatin in vivo following restoration of wild-type p53 function
Dorigo, O., Turla, S. T., Lebedeva, S., & Gjerset, R. A. (1998). Sensitization of rat glioblastoma multiforme to cisplatin in vivo following restoration of wild-type p53 function. JOURNAL OF NEUROSURGERY, 88(3), 535–540. -
Progress and prospects in vaccine therapy for gynecologic cancers.
Gurski, K. J., & Steller, M. A. (1997). Progress and prospects in vaccine therapy for gynecologic cancers. Oncology (Williston Park, N.Y.), 11(11), 1727-? -
Construction and characterization of retroviral vectors for interleukin-2 gene therapy
Fakhrai, H., Shawler, D. L., VANBEVEREN, C., Lin, H., Dorigo, O., Solomon, M. J., … SOBOL, R. E. (1997). Construction and characterization of retroviral vectors for interleukin-2 gene therapy. JOURNAL OF IMMUNOTHERAPY, 20(6), 437–448. -
Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy
Fakhrai, H., Dorigo, O., Shawler, D. L., Lin, H., MERCOLA, D., Black, K. L., … SOBOL, R. E. (1996). Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 93(7), 2909–2914. -
COMPARISON OF GENE-THERAPY WITH INTERLEUKIN-2 GENE MODIFIED FIBROBLASTS AND TUMOR-CELLS IN THE MURINE CT-26 MODEL OF COLORECTAL-CARCINOMA
Shawler, D. L., Dorigo, O., Gjerset, R. A., Royston, I., SOBOL, R. E., & Fakhrai, H. (1995). COMPARISON OF GENE-THERAPY WITH INTERLEUKIN-2 GENE MODIFIED FIBROBLASTS AND TUMOR-CELLS IN THE MURINE CT-26 MODEL OF COLORECTAL-CARCINOMA. JOURNAL OF IMMUNOTHERAPY, 17(4), 201–208. -
INTERLEUKIN-2 GENE-THERAPY IN A PATIENT WITH GLIOBLASTOMA
SOBOL, R. E., Fakhrai, H., Shawler, D., GJERSET, R., Dorigo, O., Carson, C., … Royston, I. (1995). INTERLEUKIN-2 GENE-THERAPY IN A PATIENT WITH GLIOBLASTOMA. GENE THERAPY, 2(2), 164–167. -
INJECTION OF COLON-CARCINOMA PATIENTS WITH AUTOLOGOUS IRRADIATED TUMOR-CELLS AND FIBROBLASTS GENETICALLY-MODIFIED TO SECRETE INTERLEUKIN-2 (IL-2) - A PHASE-I STUDY
SOBOL, R. E., Royston, I., Fakhrai, H., Shawler, D. L., Carson, C., Dorigo, O., … Wilson, D. (1995). INJECTION OF COLON-CARCINOMA PATIENTS WITH AUTOLOGOUS IRRADIATED TUMOR-CELLS AND FIBROBLASTS GENETICALLY-MODIFIED TO SECRETE INTERLEUKIN-2 (IL-2) - A PHASE-I STUDY. HUMAN GENE THERAPY, 6(2), 195–204. -
CHARACTERIZATION OF A NEW HUMAN GLIOBLASTOMA CELL-LINE THAT EXPRESSES MUTANT P53 AND LACKS ACTIVATION OF THE PDGF PATHWAY
Gjerset, R. A., Fakhrai, H., Shawler, D. L., Turla, S., Dorigo, O., GROVERBARDWICK, A., … SOBOL, R. E. (1995). CHARACTERIZATION OF A NEW HUMAN GLIOBLASTOMA CELL-LINE THAT EXPRESSES MUTANT P53 AND LACKS ACTIVATION OF THE PDGF PATHWAY. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 31(3), 207–214. -
A NON-LYMPHOMA IDIOTYPE IS INDICATIVE AND PREDICTIVE FOR B-CELL MALIGNANCIES IN AIDS
Herndier, B., McGrath, M., Abbey, N., Wang, H. T., Ng, V., Dorigo, O., … Kohler, H. (1993). A NON-LYMPHOMA IDIOTYPE IS INDICATIVE AND PREDICTIVE FOR B-CELL MALIGNANCIES IN AIDS. HYBRIDOMA, 12(5), 529–537. -
VALUE OF BOWEL RESECTION AND PREOPERATIVE COLOSCOPY IN OVARIAN-CANCER
Dorigo, O., Meier, W., Scheidel, P., & Hepp, H. (1993). VALUE OF BOWEL RESECTION AND PREOPERATIVE COLOSCOPY IN OVARIAN-CANCER. ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 254(1-4), 966–968. -
LYMPHOCYTE SUBPOPULATIONS IN WOMEN WITH MALIGNANT-TUMORS IN CORRELATION WITH KNOWN PROGNOSTIC FACTORS AND AS DISEASE PARAMETERS DURING CYTOKINE THERAPY
ROMISCH, M., Bauer, F., Daponte, A., Meier, W., Dorigo, O., & Eiermann, W. (1993). LYMPHOCYTE SUBPOPULATIONS IN WOMEN WITH MALIGNANT-TUMORS IN CORRELATION WITH KNOWN PROGNOSTIC FACTORS AND AS DISEASE PARAMETERS DURING CYTOKINE THERAPY. ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 254(1-4), 1091–1093. -
ACTIVATION OF NEUTROPHILS IN THE MICROVASCULATURE OF THE ISCHEMIC AND REPERFUSED MYOCARDIUM
Tillmanns, H., Neumann, F. J., Tiefenbacher, C., Dorigo, O., Parekh, N., Waas, W., … Kuebler, W. (1993). ACTIVATION OF NEUTROPHILS IN THE MICROVASCULATURE OF THE ISCHEMIC AND REPERFUSED MYOCARDIUM. Presented at the 2nd Symposium of the German-Heart-Institute - Coronary Endothelium and Smooth Muscle : Basic Aspects and Clinical Consequences, BERLIN,GERMANY: W B SAUNDERS CO LTD. -
A MONOCLONAL-ANTIBODY (IF7) SPECIFIC FOR HUMAN ANTI-HIV IG INDUCES APOPTOSIS AND INHIBITS CTL ACTIVITY IN CD8+ LYMPHOCYTES FROM HIV-1 INFECTED INDIVIDUALS
Muller, S., Collins, H., Brams, P., Wang, H., Dorigo, O., McGrath, M., … Kohler, H. (1993). A MONOCLONAL-ANTIBODY (IF7) SPECIFIC FOR HUMAN ANTI-HIV IG INDUCES APOPTOSIS AND INHIBITS CTL ACTIVITY IN CD8+ LYMPHOCYTES FROM HIV-1 INFECTED INDIVIDUALS. WILEY-BLACKWELL. -
NEW TECHNIQUES FOR THE STUDY OF THE CORONARY MICROCIRCULATION - IMPORTANCE OF MEASUREMENTS OF CORONARY FLOW RESERVE IN THE CLINICAL SETTING
Tillmanns, H., Neumann, F. J., Waas, W., Mall, G., Parekh, N., Tiefenbacher, C., … Kubler, W. (1992). NEW TECHNIQUES FOR THE STUDY OF THE CORONARY MICROCIRCULATION - IMPORTANCE OF MEASUREMENTS OF CORONARY FLOW RESERVE IN THE CLINICAL SETTING. CORONARY ARTERY DISEASE, 3(7), 586–592. -
SHORT-TERM OUTCOME IN INFANTS WITH BIRTH WEIGHTS LESS-THAN 1750-G BORN TO MOTHERS WITH HELLP SYNDROME
Gortner, L., Pohlandt, F., Bartmann, P., Terinde, R., Versmold, H., & Dorigo, O. (1992). SHORT-TERM OUTCOME IN INFANTS WITH BIRTH WEIGHTS LESS-THAN 1750-G BORN TO MOTHERS WITH HELLP SYNDROME. JOURNAL OF PERINATAL MEDICINE, 20(1), 25–28. -
PHARMACOLOGICAL EFFECTS ON CORONARY MICROVESSELS DURING MYOCARDIAL-ISCHEMIA
Tillmanns, H., Neumann, F. J., Parekh, N., Dorigo, O., Tiefenbacher, C., Zimmermann, R., … Kubler, W. (1990). PHARMACOLOGICAL EFFECTS ON CORONARY MICROVESSELS DURING MYOCARDIAL-ISCHEMIA. EUROPEAN HEART JOURNAL, 11, 10–15. -
MICROCIRCULATION IN THE HYPERTROPHIC AND ISCHEMIC HEART
Tillmanns, H., Neumann, F. J., Parekh, N., Zimmermann, R., Tiefenbacher, C., Dorigo, O., … Kubler, W. (1990). MICROCIRCULATION IN THE HYPERTROPHIC AND ISCHEMIC HEART. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 39, S9–S12. -
Apoptosis of CD4+ and CD8+ cells from HIV-1 infected individuals: role of anti-idiotypic antibodies
Muller, S., Brams, P., Collins, H., Dorigo, O., & Kohler, H. (1995). Apoptosis of CD4+ and CD8+ cells from HIV-1 infected individuals: role of anti-idiotypic antibodies. Vaccine Research, Vol 4(No 4). -
Immuno-gene therapy of colon carcinoma and central nervous tumors
Sobol, R. E., Fakhrai, H., Shawler, D. L., Dorigo, O., Gjerset, R. A., Mercola, D., … Bartholomew, R. (1996). Immuno-gene therapy of colon carcinoma and central nervous tumors. In: Gene Therapy and Cancer. -
Interleukin-2 (IL-2) gene therapy with allogenic fibroblasts in the CT-26 model of murine colorectal carcinoma
Shawler, D. L., Dorigo, O., Van Beveren, C., Bartholomew, R. M., Fakhrai, H., & Sobol, R. E. (1997). Interleukin-2 (IL-2) gene therapy with allogenic fibroblasts in the CT-26 model of murine colorectal carcinoma. Oncology Reports, 4(N1). -
Gene therapy for ovarian cancer – Molecular scissors of the new millenium?
Dorigo, O., & Berek, J. S. (1998). Gene therapy for ovarian cancer – Molecular scissors of the new millenium? Journal of Gynecologic Techniques, 4. -
Synergy of transforming growth factor beta (TGF-beta) antisense and IL-2 gene therapy in the murine ovarian teratoma model
Dorigo, O., Shawler, D. L., Royston, I., Sobol, R. E., Berek, J. S., & Fakhrai, H. (1998). Synergy of transforming growth factor beta (TGF-beta) antisense and IL-2 gene therapy in the murine ovarian teratoma model. Gynecologic Oncology, (71). -
Enhanced Expression of L9'S Mutant nAChR in Adult Mice Increases the Loss of Midbrain Dopaminergic Neurons
Schwarz, J., Schwarz, S. C., Dorigo, O., Labarca, C., Deshpande, P., Gil, J., … Lester, H. A. (2006). Enhanced Expression of L9'S Mutant nAChR in Adult Mice Increases the Loss of Midbrain Dopaminergic Neurons. The Journal of the Federation of American Societies for Experimental Biology, (20 (7). -
The role of Rho GTPase in cell stiffness and cisplatin resistance in ovarian cancer cells
Sharma, S., Santiskulvong, C., Rao, J., Gimzewski, J. K., & Dorigo, O. (2014). The role of Rho GTPase in cell stiffness and cisplatin resistance in ovarian cancer cells. INTEGRATIVE BIOLOGY, 6(6), 611–17. -
Cervical cancer, version 2.2015.
Koh, W.-J., Greer, B. E., Abu-Rustum, N. R., Apte, S. M., Campos, S. M., Cho, K. R., … Scavone, J. L. (2015). Cervical cancer, version 2.2015. Journal of the National Comprehensive Cancer Network , 13(4), 395–404. -
Immunotherapeutic approaches to ovarian cancer treatment.
Chester, C., Dorigo, O., Berek, J. S., & Kohrt, H. (2015). Immunotherapeutic approaches to ovarian cancer treatment. Journal for Immunotherapy of Cancer, 3, 7-? -
Uterine Sarcoma, Version 1.2016 Featured Updates to the NCCN Guidelines
Koh, W.-J., Greer, B. E., Abu-Rustum, N. R., Apte, S. M., Campos, S. M., Cho, K. R., … Scavone, J. L. (2015). Uterine Sarcoma, Version 1.2016 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 13(11), 1321–31. -
Screening cell mechanotype by parallel microfiltration
Qi, D., Gill, N. K., Santiskulvong, C., Sifuentes, J., Dorigo, O., Rao, J., … Rowat, A. C. (2015). Screening cell mechanotype by parallel microfiltration. SCIENTIFIC REPORTS, 5. -
Disseminated Intravascular Coagulation Complicating the Conservative Management of Placenta Percreta
Judy, A. E., Lyell, D. J., Druzin, M. L., & Dorigo, O. (2015). Disseminated Intravascular Coagulation Complicating the Conservative Management of Placenta Percreta. OBSTETRICS AND GYNECOLOGY, 126(5), 1016–18. -
Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer
Moughon, D. L., He, H., Schokrpur, S., Jiang, Z. K., Yaqoob, M., David, J., … Wu, L. (2015). Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer. CANCER RESEARCH, 75(22), 4742–52. -
Screening cell mechanotype by parallel microfiltration.
Qi, D., Kaur Gill, N., Santiskulvong, C., Sifuentes, J., Dorigo, O., Rao, J., … Rowat, A. C. (2015). Screening cell mechanotype by parallel microfiltration. Scientific Reports, 5, 17595-? -
Pilot prospective evaluation of F-18-FPPRGD(2) PET/CT in patients with cervical and ovarian cancer
Minamimoto, R., Karam, A., Jamali, M., Barkhodari, A., Gambhir, S. S., Dorigo, O., & Iagaru, A. (2016). Pilot prospective evaluation of F-18-FPPRGD(2) PET/CT in patients with cervical and ovarian cancer. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 43(6), 1047–55. -
Hemophagocytic lymphohistiocytosis as a paraneoplastic syndrome associated with ovarian dysgerminoma.
Nosratian-Baskovic, M., Tan, B., Folkins, A., Chisholm, K. M., & Dorigo, O. (2016). Hemophagocytic lymphohistiocytosis as a paraneoplastic syndrome associated with ovarian dysgerminoma. Gynecologic Oncology Reports, 17, 38–41. -
Cervical Cancer, Version 2.2015 Featured Updates to the NCCN Guidelines
Koh, W.-J., Greer, B. E., Abu-Rustum, N. R., Apte, S. M., Campos, S. M., Cho, K. R., … Scavone, J. L. (2015). Cervical Cancer, Version 2.2015 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 13(4), 395–404. -
Ovarian Cancer, Version 1.2016
Morgan, R. J., Armstrong, D. K., Alvarez, R. D., Bakkum-Gamez, J. N., Behbakht, K., Chen, L.-may, … Hughes, M. (2016). Ovarian Cancer, Version 1.2016. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 14(9), 1134–63. -
Enhanced expression of hypersensitive alpha 4*nAChR in adult mice increases the loss of midbrain dopaminergic neurons
Schwarz, J., Schwarz, S. C., Dorigo, O., Stuetzer, A., Wegner, F., Labarca, C., … Lester, H. A. (2006). Enhanced expression of hypersensitive alpha 4*nAChR in adult mice increases the loss of midbrain dopaminergic neurons. FASEB JOURNAL, 20(7), 935–946. -
Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma
Santiskulvong, C., Konecny, G. E., Fekete, M., Chen, K.-Y. M., Karam, A., Mulholland, D., … Dorigo, O. (2011). Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma. CLINICAL CANCER RESEARCH, 17(8), 2373–2384. -
Interleukin-2 (IL-2) gene therapy with allogeneic fibroblasts in the CT-26 model of murine colorectal carcinoma
Shawler, D. L., Dorigo, O., VANBEVEREN, C., Bartholomew, R. M., Fakhrai, H., & SOBOL, R. E. (1997). Interleukin-2 (IL-2) gene therapy with allogeneic fibroblasts in the CT-26 model of murine colorectal carcinoma. ONCOLOGY REPORTS, 4(1), 135–138. -
Imaging of Tumor-Associated Macrophages in a Transgenic Mouse Model of Orthotopic Ovarian Cancer.
He, H., Chiu, A. C., Kanada, M., Schaar, B. T., Krishnan, V., Contag, C. H., & Dorigo, O. (2017). Imaging of Tumor-Associated Macrophages in a Transgenic Mouse Model of Orthotopic Ovarian Cancer. Molecular Imaging and Biology . -
Immunotherapy in ovarian cancer.
Krishnan, V., Berek, J. S., & Dorigo, O. (2016). Immunotherapy in ovarian cancer. Current Problems in Cancer. -
Vulvar Cancer, Version 1.2017 Clinical Practice Guidelines in Oncology
Koh, W.-J., Greer, B. E., Abu-Rustum, N. R., Campos, S. M., Cho, K. R., Chon, H. S., … Scavone, J. (2017). Vulvar Cancer, Version 1.2017 Clinical Practice Guidelines in Oncology. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 15(1), 92–120. -
Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.
Morgan, R. J., Armstrong, D. K., Alvarez, R. D., Bakkum-Gamez, J. N., Behbakht, K., Chen, L.-may, … Hughes, M. (2016). Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network , 14(9), 1134–1163. -
Immunotherapy in ovarian cancer
Krishnan, V., Berek, J. S., & Dorigo, O. (2017). Immunotherapy in ovarian cancer. CURRENT PROBLEMS IN CANCER, 41(1), 48–63. -
Improving Care With a Portfolio of Physician-Led Cancer Quality Measures at an Academic Center
Porter, J. B. (2017). Improving Care With a Portfolio of Physician-Led Cancer Quality Measures at an Academic Center. Improving Care With a Portfolio of Physician-Led Cancer Quality Measures at an Academic Center, 13(8), e673–e682. -
Tumor associated macrophages in gynecologic cancers.
Krishnan, V., Schaar, B., Tallapragada, S., & Dorigo, O. (2018). Tumor associated macrophages in gynecologic cancers. Gynecologic Oncology. -
Cell-based immunotherapy in gynecologic malignancies.
Schaar, B., Krishnan, V., Tallapragada, S., & Dorigo, O. (2018). Cell-based immunotherapy in gynecologic malignancies. Current Opinion in Obstetrics & Gynecology, 30(1), 23–30. -
Uterine Neoplasms, Version 1.2018 Clinical Practice Guidelines in Oncology
Koh, W.-J., Abu-Rustum, N. R., Bean, S., Bradley, K., Campos, S. M., Cho, K. R., … Scavone, J. L. (2018). Uterine Neoplasms, Version 1.2018 Clinical Practice Guidelines in Oncology. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 16(2), 170–99. -
Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials
MacKay, H. J., Levine, D. A., Bae-Jump, V. L., Bell, D. W., McAlpine, J. N., Santin, A., … Kohn, E. C. (2017). Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials. ONCOTARGET, 8(48), 84579–94. -
Hypoxic signaling in the tumor-mesothelial niche promotes collagen remodeling and ovarian cancer metastasis.
Foreman, K., Fuh, K., SorianoJAL, M., Dorigo, O., Krishnan, V., Shehade, H., … Rankin, E. (2018). Hypoxic signaling in the tumor-mesothelial niche promotes collagen remodeling and ovarian cancer metastasis. CLINICAL CANCER RESEARCH, 24(15), 57. -
Women's cancer: Advancing molecular and immunotherapy
Dorigo, O. (2017). Women's cancer: Advancing molecular and immunotherapy. CURRENT PROBLEMS IN CANCER, 41(1), 7. -
Single cell analysis of ascites macrophages in ovarian cancer
He, H. M., Yu, F. B., Quake, S. R., & Dorigo, O. (2015). Single cell analysis of ascites macrophages in ovarian cancer. CANCER RESEARCH, 75. -
Parallel microfiltration (PMF): A novel method to screen cell mechanotype
Wiedemeyer, W.-R., Qi, D., Gi, N. K., Santiskulvong, C., Dorigo, O., Rao, J. Y., … Rowat, A. C. (2015). Parallel microfiltration (PMF): A novel method to screen cell mechanotype. CANCER RESEARCH, 75. -
Comprehensive genomic profiling (CGP) of cervical squamous cell carcinoma (cSCC) to identifiy targeted therapy options.
Elvin, J. A., Bailey, M., Carneiro, B. A., Ali, S. M., Vergilio, J.-A., Palma, N. A., … Dorigo, O. (2015). Comprehensive genomic profiling (CGP) of cervical squamous cell carcinoma (cSCC) to identifiy targeted therapy options. JOURNAL OF CLINICAL ONCOLOGY, 33(15). -
M2 macrophage inhibition reverses vascular leaks that cause malignant ascites in late-stage epithelial ovarian cancer
Moughon, D., He, H., Schokrpur, S., Jiang, Z., Yaqoob, M., David, J., … Wu, L. (2015). M2 macrophage inhibition reverses vascular leaks that cause malignant ascites in late-stage epithelial ovarian cancer. CANCER RESEARCH, 75(1). -
Mutational analysis of serous ovarian cancer using Ion Torrent sequencing
Masghati, S., Dorigo, O., & Santisvkulvong, C. (2014). Mutational analysis of serous ovarian cancer using Ion Torrent sequencing. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
The role of tumor associated macrophages in ovarian cancer
He, H., Moughon, D. L., Hillerup, C., ElMasri, W., Wu, L., & Dorigo, O. (2014). The role of tumor associated macrophages in ovarian cancer. GYNECOLOGIC ONCOLOGY, 135(2), 385. -
Cell-based immunotherapy in gynecologic malignancies.
Schaar, B., Krishnan, V., Tallapragada, S., Chanana, A., & Dorigo, O. (2018). Cell-based immunotherapy in gynecologic malignancies. Current Opinion in Obstetrics & Gynecology. -
A scalable filtration method for high throughput screening based on cell deformability.
Gill, N. K., Ly, C., Nyberg, K. D., Lee, L., Qi, D., Tofig, B., … Rowat, A. C. (2018). A scalable filtration method for high throughput screening based on cell deformability. Lab on a Chip. -
Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.
Koh, W.-J., Abu-Rustum, N. R., Bean, S., Bradley, K., Campos, S. M., Cho, K. R., … Scavone, J. L. (2019). Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN, 17(1), 64–84. -
Collagen remodeling in the hypoxic tumor-mesothelial niche promotes ovarian cancer metastasis.
Natarajan, S., Foreman, K. M., Soriano, M. I., Rossen, N. S., Shehade, H., Fregoso, D. R., … Rankin, E. B. (2019). Collagen remodeling in the hypoxic tumor-mesothelial niche promotes ovarian cancer metastasis. Cancer Research. -
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins.
Malaker, S. A., Pedram, K., Ferracane, M. J., Bensing, B. A., Krishnan, V., Pett, C., … Bertozzi, C. R. (2019). The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Proceedings of the National Academy of Sciences of the United States of America. -
Sentinel lymph node biopsies in endometrial cancer - practice patterns among Gynecologic Oncologists in the United States.
Renz, M., Diver, E., English, D., Kidd, E., Dorigo, O., & Karam, A. (2019). Sentinel lymph node biopsies in endometrial cancer - practice patterns among Gynecologic Oncologists in the United States. Journal of Minimally Invasive Gynecology. -
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
Malaker, S. A., Pedram, K., Ferracane, M. J., Bensing, B. A., Krishnan, V., Pett, C., … Bertozzi, C. R. (2019). The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(15), 7278–87. -
Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis
Natarajan, S., Foreman, K. M., Soriano, M., Rossen, N. S., Shehade, H., Fregoso, D. R., … Rankin, E. B. (2019). Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis. CANCER RESEARCH, 79(9), 2271–84. -
Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx.
Möckl, L., Pedram, K., Roy, A. R., Krishnan, V., Gustavsson, A.-K. K., Dorigo, O., … Moerner, W. E. (2019). Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx. Developmental Cell. -
Immunotherapy in Gynecologic Cancers: What We Know Now and Where We Are Headed.
Levinson, K., Dorigo, O., Rubin, K., & Moore, K. (2019). Immunotherapy in Gynecologic Cancers: What We Know Now and Where We Are Headed. American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting, (39), e126–e140. -
Omentum immune microenvironment: Metastatic niche for ovarian cancer
Krishnan, V., Raju, P. A., Vierkoetter, K., Patel, S., Youngyunpipatkul, J., Tallapragada, S., … Dorigo, O. (2018). Omentum immune microenvironment: Metastatic niche for ovarian cancer. CANCER RESEARCH, 78(13). -
ASCO 2019 meeting review.
Diver, E., Dorigo, O., & Berek, J. (2019). ASCO 2019 meeting review. Journal of Gynecologic Oncology, 30(5), e107. -
CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.
Barkal, A. A., Brewer, R. E., Markovic, M., Kowarsky, M., Barkal, S. A., Zaro, B. W., … Weissman, I. L. (2019). CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. Nature. -
DPX-Survivac and intermittent low-dose cyclophosphamide (CPA) with or without epacadostat (E) in the treatment of subjects with advanced recurrent epithelial ovarian cancer (DeCidE(1) trial): T cell responses and tumor infiltration correlate with tumor regression.
Tanyi, J. L., Dorigo, O., Oza, A. M., Strauss, J. F., Pejovic, T., Ghamande, S. A., … Rosu, G. N. (2019). DPX-Survivac and intermittent low-dose cyclophosphamide (CPA) with or without epacadostat (E) in the treatment of subjects with advanced recurrent epithelial ovarian cancer (DeCidE(1) trial): T cell responses and tumor infiltration correlate with tumor regression. JOURNAL OF CLINICAL ONCOLOGY, 37(15). -
C-C chemokine receptor type 1 is a prognostic indicator in ovarian cancer
Chanana, A. M., Krishnan, V., Tallapragada, S., & Dorigo, O. (2019). C-C chemokine receptor type 1 is a prognostic indicator in ovarian cancer. CANCER RESEARCH, 79(13). -
THE HYPOXIC TUMOR-MESOTHELIAL NICHE PROMOTES OVARIAN CANCER METASTASIS THROUGH COLLAGEN REMODELING
Natarajan, S., Foreman, K., Soriano, M., Shehade, H., Fregoso, D., Eggold, J., … Rankin, E. B. (2019). THE HYPOXIC TUMOR-MESOTHELIAL NICHE PROMOTES OVARIAN CANCER METASTASIS THROUGH COLLAGEN REMODELING. CLINICAL CANCER RESEARCH, 25(22), 168. -
OMENTAL MACROPHAGES REGULATE OVARIAN CANCER METASTATIC COLONIZATION THROUGH THE CCL6-CCR1 SIGNALING AXIS
Krishnan, V., Tallapragada, S., Schaar, B., Chanana, A., Rinker-Schaeffer, C., & Dorigo, O. (2019). OMENTAL MACROPHAGES REGULATE OVARIAN CANCER METASTATIC COLONIZATION THROUGH THE CCL6-CCR1 SIGNALING AXIS. CLINICAL CANCER RESEARCH, 25(22), 162. -
Gestational Trophoblastic Neoplasia, Version 2.2019
Abu-Rustum, N. R., Yashar, C. M., Bean, S., Bradley, K., Campos, S. M., Chon, H. S., … Scavone, J. (2019). Gestational Trophoblastic Neoplasia, Version 2.2019. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 17(11), 1374–91. -
Sentinel Lymph Node Biopsies in Endometrial Cancer: Practice Patterns among Gynecologic Oncologists in the United States
Renz, M., Diver, E., English, D., Kidd, E., Dorigo, O., & Karam, A. (2020). Sentinel Lymph Node Biopsies in Endometrial Cancer: Practice Patterns among Gynecologic Oncologists in the United States. JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY, 27(2), 482–88. -
Quantitative super-resolution microscopy of the mammalian glycocalyx
Mockl, L., Pedram, K., Roy, A., Krishnan, V., Gustavsson, A.-K., Dorigo, O., … Moerner, W. (2019). Quantitative super-resolution microscopy of the mammalian glycocalyx. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. AMER CHEMICAL SOC. -
DPX-Survivac, a novel T-cell immunotherapy, to induce robust T-cell responses in advanced ovarian cancer
Dorigo, O., Fiset, S., MacDonald, L. D., Bramhecha, Y., Hrytsenko, O., Dirk, B., … Stanford, M. (2020). DPX-Survivac, a novel T-cell immunotherapy, to induce robust T-cell responses in advanced ovarian cancer. JOURNAL OF CLINICAL ONCOLOGY, 38(5). -
Incorporating Parp-inhibitors in Primary and Recurrent Ovarian Cancer: A Meta-analysis of 12 phase II/III randomized controlled trials.
Ruscito, I., Bellati, F., Ray-Coquard, I., Mirza, M. R., du Bois, A., Gasparri, M. L., … Braicu, E. I. (2020). Incorporating Parp-inhibitors in Primary and Recurrent Ovarian Cancer: A Meta-analysis of 12 phase II/III randomized controlled trials. Cancer Treatment Reviews, 87, 102040. -
Minimally Invasive Surgery for Gynecologic Cancers-A Cautionary Tale.
Karam, A., & Dorigo, O. (2020). Minimally Invasive Surgery for Gynecologic Cancers-A Cautionary Tale. JAMA Oncology. -
Vulvar sarcoma outcomes by histologic subtype: a Surveillance, Epidemiology, and End Results (SEER) database review.
Johnson, S., Renz, M., Wheeler, L., Diver, E., Dorigo, O., Litkouhi, B., … Karam, A. (2020). Vulvar sarcoma outcomes by histologic subtype: a Surveillance, Epidemiology, and End Results (SEER) database review. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. -
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins.
Shon, D. J., Malaker, S. A., Pedram, K., Yang, E., Krishnan, V., Dorigo, O., & Bertozzi, C. R. (2020). An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. -
Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1.
Krishnan, V., Tallapragada, S., Schaar, B., Kamat, K., Chanana, A. M., Zhang, Y., … Dorigo, O. (2020). Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1. Communications Biology, 3(1), 524. -
Infiltration of tumor by T cells following treatment with DPX-Survivac and intermittent low dose cyclophosphamide (CPA) leads to clinical responses in advanced recurrent ovarian cancer (OvCa).
Dorigo, O., MacDonald, L. D., Schindler, J., Bramhecha, Y., Torrey, H., Kaliaperumal, V., … Fiset, S. (2020). Infiltration of tumor by T cells following treatment with DPX-Survivac and intermittent low dose cyclophosphamide (CPA) leads to clinical responses in advanced recurrent ovarian cancer (OvCa). JOURNAL OF CLINICAL ONCOLOGY, 38(15). -
Development of Therapeutic Vaccines for Ovarian Cancer.
Chow, S., Berek, J. S., & Dorigo, O. (2020). Development of Therapeutic Vaccines for Ovarian Cancer. Vaccines, 8(4). -
Cell-based immunotherapy in gynecologic malignancies.
Kamat, K., Krishnan, V., Berek, J. S., & Dorigo, O. (2020). Cell-based immunotherapy in gynecologic malignancies. Current Opinion in Obstetrics & Gynecology. -
Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice.
Levy, K., Natarajan, S., Wang, J., Chow, S., Eggold, J. T., Loo, P. E., … Rankin, E. B. (2020). Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice. Scientific Reports, 10(1), 21600. -
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
Shon, D. J., Malaker, S. A., Pedram, K., Yang, E., Krishnan, V., Dorigo, O., & Bertozzi, C. R. (2020). An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins. GLYCOBIOLOGY. OXFORD UNIV PRESS INC. -
Phase II trial evaluating efficacy of a Fitbit program for improving the health of endometrial cancer survivors.
Rahimy, E., Usoz, M., von Eyben, R., Fujimoto, D., Watanabe, D., Karam, A., … Kidd, E. (2021). Phase II trial evaluating efficacy of a Fitbit program for improving the health of endometrial cancer survivors. Gynecologic Oncology. -
FLASH irradiation enhances the therapeutic index of abdominal radiotherapy in mice
Natarajan, S., Levy, K., Wang, J., Chow, S., Eggold, J., Loo, P., … Rankin, E. B. (2020). FLASH irradiation enhances the therapeutic index of abdominal radiotherapy in mice. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Total abdominal ultra-rapid FLASH irradiation enhances the efficacy of PD-1 inhibition in preclinical models of ovarian cancer
Chow, S., Eggold, J. T., Levy, K., Wang, J., Manjappa, R., Breitkreutz, D. Y., … Rankin, E. B. (2020). Total abdominal ultra-rapid FLASH irradiation enhances the efficacy of PD-1 inhibition in preclinical models of ovarian cancer. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging.
Kassuhn, W., Klein, O., Darb-Esfahani, S., Lammert, H., Handzik, S., Taube, E. T., … Braicu, E. I. (2021). Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging. Cancers, 13(7). -
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2).
Swisher, E. M., Kwan, T. T., Oza, A. M., Tinker, A. V., Ray-Coquard, I., Oaknin, A., … McNeish, I. A. (2021). Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2). Nature Communications, 12(1), 2487. -
Long-term efficacy of megestrol acetate and tamoxifen in a recurrent adult granulosa cell tumor of the ovary.
Moon, A. S., & Dorigo, O. (2021). Long-term efficacy of megestrol acetate and tamoxifen in a recurrent adult granulosa cell tumor of the ovary. Gynecologic Oncology Reports, 36, 100770. -
Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling.
Qian, J., LeSavage, B. L., Hubka, K. M., Ma, C., Natarajan, S., Eggold, J. T., … Rankin, E. B. (2021). Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling. The Journal of Clinical Investigation, 131(16). -
Phase II Trial Evaluating Efficacy of a Fitbit Program for Improving the Health of Endometrial Cancer Survivors
Rahimy, E., Usoz, M., von Eyben, R., Fujimoto, D., Watanabe, D., Karam, A., … Kidd, E. (2021). Phase II Trial Evaluating Efficacy of a Fitbit Program for Improving the Health of Endometrial Cancer Survivors. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS. LIPPINCOTT WILLIAMS & WILKINS. -
Prospective molecular classification of endometrial carcinomas: institutional implementation, practice, and clinical experience.
Devereaux, K. A., Weiel, J. J., Pors, J., Steiner, D. F., Ho, C., Charu, V., … Howitt, B. E. (2021). Prospective molecular classification of endometrial carcinomas: institutional implementation, practice, and clinical experience. Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. -
Classification of molecular subtypes of high-grade serous ovarian cancer by MALDI-Imaging.
Kassuhn, W. N., Klein, O., Darb-Esfahani, S., Lammert, H., Handzik, S., Taube, E. T., … Braicu, E. I. (2021). Classification of molecular subtypes of high-grade serous ovarian cancer by MALDI-Imaging. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Abdominopelvic FLASH Irradiation Improves PD-1 Immune Checkpoint Inhibition in Preclinical Models of Ovarian Cancer.
Eggold, J. T., Chow, S., Melemenidis, S., Wang, J., Natarajan, S., Loo, P. E., … Rankin, E. B. (2021). Abdominopelvic FLASH Irradiation Improves PD-1 Immune Checkpoint Inhibition in Preclinical Models of Ovarian Cancer. Molecular Cancer Therapeutics. -
Cell-based immunotherapies in gynecologic cancers.
Lang, S. M., & Dorigo, O. (1800). Cell-based immunotherapies in gynecologic cancers. Current Opinion in Obstetrics & Gynecology, 34(1), 10–14. -
Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease.
Kibbi, N., Owen, J. L., Worley, B., Wang, J. X., Harikumar, V., Downing, M. B., … Alam, M. (2022). Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease. JAMA Oncology. -
Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.
Gershenson, D. M., Miller, A., Brady, W. E., Paul, J., Carty, K., Rodgers, W., … Gourley, C. (2022). Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial. Lancet (London, England), 399(10324), 541–553. -
Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial
Gershenson, D. M., Miller, A., Brady, W. E., Paul, J., Carty, K., Rodgers, W., … Gourley, C. (2022). Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial. LANCET, 399(10324), 541–553. -
IDENTIFICATION OF POTENTIAL RESPONSE PREDICTORS TO MAVEROPEPIMUT-S (DPX-SURVIVAC), A NOVEL T CELL ACTIVATING IMMUNOTHERAPY, IN PATIENTS WITH ADVANCED RECURRENT OVARIAN CANCER
Dorigo, O., Ebrahimizadeh, W., Kennedy, B., MacDonald, L., Fiset, S., Villella, J., … Bramhecha, Y. (2021). IDENTIFICATION OF POTENTIAL RESPONSE PREDICTORS TO MAVEROPEPIMUT-S (DPX-SURVIVAC), A NOVEL T CELL ACTIVATING IMMUNOTHERAPY, IN PATIENTS WITH ADVANCED RECURRENT OVARIAN CANCER. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
Predictive biomarker for surgical outcome in patients with advanced primary high-grade serous ovarian cancer. Are we there yet? An analysis of the prospective biobank for ovarian cancer.
Keunecke, C., Kulbe, H., Dreher, F., Taube, E. T., Chekerov, R., Horst, D., … Braicu, E. I. (2022). Predictive biomarker for surgical outcome in patients with advanced primary high-grade serous ovarian cancer. Are we there yet? An analysis of the prospective biobank for ovarian cancer. Gynecologic Oncology. -
Revealing the human mucinome.
Malaker, S. A., Riley, N. M., Shon, D. J., Pedram, K., Krishnan, V., Dorigo, O., & Bertozzi, C. R. (2022). Revealing the human mucinome. Nature Communications, 13(1), 3542. -
Macrophage-derived CCL23 upregulates expression of T-cell exhaustion markers in ovarian cancer.
Kamat, K., Krishnan, V., & Dorigo, O. (2022). Macrophage-derived CCL23 upregulates expression of T-cell exhaustion markers in ovarian cancer. British Journal of Cancer. -
Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial
Gershenson, D. M., Miller, A., Brady, W. E., Paul, J., Carty, K., Rodgers, W., … Gourley, C. (2022). Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial. LANCET, 399(10324), 541–553. -
Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.
Vergote, I., Gonzalez-Martin, A., Lorusso, D., Gourley, C., Mirza, M. R., Kurtz, J.-E., … Bookman, M. A. (2022). Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup. The Lancet. Oncology, 23(8), e374–e384. -
Technetium Tc 99m tilmanocept fails to detect sentinel lymph nodes in endometrial cancer.
Reddy, R. A., Moon, A. S., Chow, S., Heilbroner, L., Howitt, B., Diver, E., … Karam, A. (2022). Technetium Tc 99m tilmanocept fails to detect sentinel lymph nodes in endometrial cancer. Gynecologic Oncology Reports, 43, 101054. -
Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS)Consortium.
Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele, A., … Braicu, E. I. (2022). Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS)Consortium. Annals of Surgical Oncology. -
ASO Visual Abstract: Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.
Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele, A., … Braicu, E. I. (2022). ASO Visual Abstract: Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium. Annals of Surgical Oncology. -
Monocytes - A Promising New TRAIL in Ovarian Cancer Cell Therapy.
Chow, S., & Dorigo, O. (2022). Monocytes - A Promising New TRAIL in Ovarian Cancer Cell Therapy. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
A phase 1 open label, first in human trial to study safety and tolerability of NK-T cells combined with vvDD: An accelerated dose escalation in multiple tumor types.
Dorigo, O., Contag, P. R., Moser, J., Patel, S. P., & Frohlich, M. W. (2022). A phase 1 open label, first in human trial to study safety and tolerability of NK-T cells combined with vvDD: An accelerated dose escalation in multiple tumor types. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Maveropepimut-S, a DPX-based immune-educating therapy, shows promising and durable clinical benefit in patients with recurrent ovarian cancer, a phase 2 trial.
Dorigo, O., Oza, A. M., Pejovic, T., Ghatage, P., Ghamande, S., Provencher, D., … Fiset, S. (2023). Maveropepimut-S, a DPX-based immune-educating therapy, shows promising and durable clinical benefit in patients with recurrent ovarian cancer, a phase 2 trial. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Adjuvant radiation therapy in early-stage endometrial cancer with abnormal beta-catenin expression is associated with improved local control.
Hui, C., Mendoza, M. G., Snyder, J., Dorigo, O., Litkouhi, B., Renz, M., … Kidd, E. A. (2023). Adjuvant radiation therapy in early-stage endometrial cancer with abnormal beta-catenin expression is associated with improved local control. Gynecologic Oncology, 174, 42–48. -
Does lymph node assessment change the prognostic significance of substantial LVSI and p53 status in endometrial endometrioid carcinoma?
Hui, C., Mendoza, M. G., von Eyben, R., Dorigo, O., Litkouhi, B., Renz, M., … Kidd, E. (2023). Does lymph node assessment change the prognostic significance of substantial LVSI and p53 status in endometrial endometrioid carcinoma? Gynecologic Oncology, 177, 150–156. -
Aberrant nuclear ß-catenin distribution does not prognosticate recurrences of endometrioid endometrial cancers - A retrospective single-institutional study.
Beshar, I., Moon, A. S., Darji, H., Liu, C., Jennings, M. T., Dorigo, O., … Renz, M. (2023). Aberrant nuclear ß-catenin distribution does not prognosticate recurrences of endometrioid endometrial cancers - A retrospective single-institutional study. Gynecologic Oncology, 179, 85–90.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected
- A Study of Sapanisertib, Combination of Sapanisertib With MLN1117, Paclitaxel and Combination of Sapanisertib With Paclitaxel in Women With Endometrial Cancer
- Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer
- CT Antigen TCR-redirected T Cells for Ovarian Cancer.
- Veliparib With Carboplatin and Paclitaxel and as Continuation Maintenance Therapy in Adults With Newly Diagnosed Stage III or IV, High-grade Serous, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
- A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
- Cvac as Maintenance Treatment in Patients With Epithelial Ovarian Cancer in Complete Remission Following First-line Chemotherapy or Second-line Treatment
- A Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian Cancer
Practice Locations
Gynecologic Cancer Program in Palo Alto Palo Alto, CA
Palo Alto, CAGynecologic Cancer Program in Palo Alto
900 Blake Wilbur Drive, 1st Floor
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereStanford Women's Cancer Center Palo Alto, CA
Palo Alto, CAStanford Women's Cancer Center
900 Blake Wilbur Drive, 1st Floor
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereImportant Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
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Referring Physicians
PHYSICIAN HELPLINE
Fax: 650-320-9443
Monday–Friday, 8 a.m.–5 p.m.
Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
- Send referrals online
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